Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 110200480 . T A CCDS806.1:NM_147148.2:c.346Tac>Aac_NP_671489.1:p.116Y>N Homo sapiens glutathione S-transferase mu 4 (GSTM4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4gtu 1 Q03013 100.0 5e-165 X-RAY
 2000-01-14 TYR A:115 A:115 109.0 0.474 T -110.7 -1.5 109.0 0.474 0.0
TYR B:115 B:115 103.0 0.448 T -99.4 27.2 103.0 0.448 0.0
TYR C:115 C:115 100.0 0.435 T -102.5 -1.7 NA NA NA
TYR D:115 D:115 105.0 0.457 T -98.0 12.4 NA NA NA
TYR E:115 E:115 127.0 0.552 H -98.0 -16.4 NA NA NA
TYR F:115 F:115 97.0 0.422 H -112.7 -6.2 NA NA NA
TYR G:115 G:115 103.0 0.448 H -75.2 -39.9 NA NA NA
TYR H:115 H:115 81.0 0.352 S -105.4 -15.4 NA NA NA
1xw6 1 P09488 86.7 6e-145 X-RAY
 2004-12-21 TYR A:116 A:115 82.0 0.357 S -90.9 -14.0 82.0 0.357 0.0 GSH
HOH
 5.599
3.283
 OH
OH
 SG2
O
TYR B:116 B:115 83.0 0.361 S -90.0 -13.8 83.0 0.361 0.0 GSH
HOH
 5.612
3.132
 OH
O
 SG2
O
TYR C:116 C:115 83.0 0.361 S -90.9 -14.5 NA NA NA
TYR D:116 D:115 83.0 0.361 H -91.2 -15.0 NA NA NA
1xwk 1 P09488 86.7 6e-145 X-RAY
 2004-12-21 TYR A:116 A:115 82.0 0.357 T -108.3 -5.9 82.0 0.357 0.0 GDN
HOH
 3.159
3.124
 CD2
OH
 O4B
O
TYR B:116 B:115 83.0 0.361 S -102.5 -9.7 NA NA NA
TYR C:116 C:115 84.0 0.365 T -106.1 -8.1 84.0 0.365 0.0 GDN
HOH
 3.088
3.459
 CD2
OH
 O4B
O
1yj6 1 P09488 86.7 6e-145 X-RAY
 2005-02-01 TYR A:116 A:115 81.0 0.352 S -93.5 -11.8 81.0 0.352 0.0 ZN
GSH
HOH
 4.415
6.484
3.665
 OH
OH
OH
 ZN
SG2
O
TYR B:116 B:115 79.0 0.343 H -96.1 -14.5 79.0 0.343 0.0 ZN
GSH
HOH
 4.713
6.515
3.370
 OH
OH
OH
 ZN
SG2
O
TYR C:116 C:115 87.0 0.378 H -90.2 -14.5 NA NA NA
2f3m 1 P09488 86.7 6e-145 X-RAY
 2006-04-25 TYR A:116 A:115 84.0 0.365 T -109.3 -6.9 84.0 0.365 0.0 GTD
HOH
 2.829
3.873
 OH
CD1
 O21
O
TYR B:116 B:115 83.0 0.361 T -109.1 -8.9 83.0 0.361 0.0 GTD
HOH
 2.854
7.169
 OH
CE2
 O21
O
TYR C:116 C:115 86.0 0.374 T -106.1 -6.2 NA NA NA
TYR D:116 D:115 84.0 0.365 T -106.2 -7.4 NA NA NA
TYR E:116 E:115 83.0 0.361 T -110.0 -6.4 NA NA NA
TYR F:116 F:115 86.0 0.374 T -109.6 -7.3 NA NA NA
7beu 1 P09488 86.7 6e-145 X-RAY
 2022-01-12 TYR A:116 A:115 81.0 0.352 T -98.6 -4.3 81.0 0.352 0.0 HOH
 3.217
 OH
 O
TYR B:116 B:115 78.0 0.339 T -98.0 -0.5 NA NA NA
TYR C:116 C:115 88.0 0.383 T -97.5 -2.9 NA NA NA
TYR D:116 D:115 84.0 0.365 H -100.2 -5.4 84.0 0.365 0.0 HOH
 3.190
 OH
 O
1gtu 1 P09488 87.04 3e-144 X-RAY
 1999-02-02 TYR A:115 A:115 93.0 0.404 H -103.9 -21.4 93.0 0.404 0.0 HOH
 3.397
 OH
 O
TYR B:115 B:115 92.0 0.4 H -100.5 -22.2 92.0 0.4 0.0 HOH
 3.870
 OH
 O
TYR C:115 C:115 96.0 0.417 H -102.4 -9.5 NA NA NA
TYR D:115 D:115 93.0 0.404 H -104.0 -9.4 NA NA NA
2c4j 1 P28161 82.57 5e-139 X-RAY
 2005-10-26 TYR A:116 A:116 79.0 0.343 H -93.4 -8.9 79.0 0.343 0.0 GSO
HOH
 3.661
2.797
 OH
O
 CM1
O
TYR B:116 B:116 86.0 0.374 H -101.6 -5.9 86.0 0.374 0.0 GSO
HOH
 4.125
2.662
 OH
OH
 CM1
O
TYR C:116 C:116 79.0 0.343 H -96.2 -7.0 NA NA NA
TYR D:116 D:116 79.0 0.343 T -97.3 -1.8 NA NA NA
1xw5 1 P28161 83.33 6e-139 X-RAY
 2004-11-30 TYR A:115 A:115 85.0 0.37 T -102.0 -1.6 85.0 0.37 0.0 GSH
HOH
 6.127
2.757
 OH
O
 SG2
O
TYR B:115 B:115 79.0 0.343 T -103.4 -2.7 79.0 0.343 0.0 GSH
HOH
 6.287
3.656
 OH
CB
 SG2
O
1ykc 1 P28161 83.33 6e-139 X-RAY
 2005-01-25 TYR A:115 A:115 76.0 0.33 H -97.6 -14.4 76.0 0.33 0.0 GDS
HOH
 2.856
2.777
 OH
O
 O2
O
TYR B:115 B:115 82.0 0.357 H -101.8 -17.2 82.0 0.357 0.0 GDS
HOH
 2.906
3.514
 OH
CB
 O2
O
2ab6 1 P28161 83.33 6e-139 X-RAY
 2005-08-02 TYR A:115 A:115 80.0 0.348 T -98.0 -8.9 80.0 0.348 0.0 GSM
HOH
 4.567
6.605
 OH
C
 C4
O
TYR B:115 B:115 81.0 0.352 H -98.9 -9.3 81.0 0.352 0.0 GSM
HOH
 4.681
2.974
 OH
O
 C4
O
TYR C:115 C:115 81.0 0.352 H -99.8 -11.8 NA NA NA
TYR D:115 D:115 82.0 0.357 H -101.7 -11.0 NA NA NA
2gtu 1 P28161 83.33 6e-139 X-RAY
 1999-03-02 TYR A:115 A:115 83.0 0.361 H -97.6 -9.0 83.0 0.361 0.0 HOH
 7.470
 CE2
 O
TYR B:115 B:115 80.0 0.348 H -105.7 -7.3 80.0 0.348 0.0 HOH
 6.601
 OH
 O
3gtu 1 P28161 83.33 6e-139 X-RAY
 1999-07-29 TYR A:115 A:115 77.0 0.335 H -99.0 -19.8 77.0 0.335 0.0 HOH
 2.762
 OH
 O
TYR C:115 C:115 81.0 0.352 H -98.7 -14.6 NA NA NA
3gur 1 P28161 83.33 6e-139 X-RAY
 2009-10-27 TYR A:115 A:115 76.0 0.33 T -98.5 -7.8 76.0 0.33 0.0 BYG
HOH
 3.572
6.733
 OH
OH
 CE6
O
TYR B:115 B:115 81.0 0.352 H -107.8 -19.5 81.0 0.352 0.0 GSH
HOH
 6.305
4.929
 OH
CE2
 SG2
O
TYR C:115 C:115 81.0 0.352 H -97.8 -8.2 NA NA NA
TYR D:115 D:115 79.0 0.343 H -96.7 -16.1 NA NA NA
5hwl 1 P28161 83.33 6e-139 X-RAY
 2017-11-08 TYR A:115 A:115 79.0 0.343 T -104.0 -2.9 79.0 0.343 0.0 GSH
NNE
HOH
 6.472
3.741
4.142
 OH
OH
CE2
 SG2
CBK
O
TYR B:115 B:115 77.0 0.335 T -106.8 -2.5 77.0 0.335 0.0 GSH
NNE
HOH
 6.336
3.619
4.200
 OH
OH
OH
 SG2
CAL
O
1hna 1 P28161 82.87 9e-138 X-RAY
 1994-01-31 TYR A:115 A:115 88.0 0.383 S -82.5 30.9 88.0 0.383 0.0 GDN
HOH
 5.216
2.597
 OH
OH
 SG2
O
1hnb 1 P28161 82.87 9e-138 X-RAY
 1994-01-31 TYR A:115 A:115 171.0 0.743 H -65.8 -35.7 169.0 0.735 0.008 B:P28161:0.009
 GDN
 3.006
 OH
 CB2
TYR B:115 B:115 96.0 0.417 S -84.3 -7.1 96.0 0.417 0.0 GDN
 4.413
 OH
 SG2
1hnc 1 P28161 82.87 9e-138 X-RAY
 1994-01-31 TYR A:115 A:115 82.0 0.357 T -107.4 -23.3 82.0 0.357 0.0 GDN
 8.249
 CE1
 SG2
TYR B:115 B:115 142.0 0.617 T -64.5 -6.8 142.0 0.617 0.0 GDN
 3.329
 OH
 SG2
TYR C:115 C:115 148.0 0.643 H -82.2 -41.8 NA NA NA
TYR D:115 D:115 157.0 0.683 T -81.4 26.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q03013-f1 1 Q03013 100.0 3e-166 TYR A:116 A:116 84.0 0.365 H -88.4 -12.7
af-p09488-f1 1 P09488 86.7 3e-145 TYR A:116 A:116 89.0 0.387 T -93.7 -6.4
af-p28161-f1 1 P28161 83.03 6e-140 TYR A:116 A:116 84.0 0.365 H -97.7 -5.6
af-p46439-f1 1 P46439 83.03 1e-134 TYR A:116 A:116 84.0 0.365 H -100.0 -3.0