Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 110211610 | . | A | C | CCDS808.1:NM_000848.3:c.176aAt>aCt_NP_000839.1:p.59N>T | Homo sapiens glutathione S-transferase mu 2 (GSTM2), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 2c4j | 1 | P28161 | 99.54 | 3e-164 |
X-RAY |
2005-10-26 | ASN | A:59 | A:59 | 68.0 | 0.425 | -168.5 | 168.0 | 53.0 | 0.331 | 0.094 |
B:P28161:0.094 |
GSO HOH |
2.888 2.842 |
OD1 ND2 |
N3 O |
||
| ASN | B:59 | B:59 | 68.0 | 0.425 | -168.0 | 168.2 | 53.0 | 0.331 | 0.094 |
A:P28161:0.094 |
GSO HOH |
2.917 2.902 |
OD1 ND2 |
N3 O |
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| ASN | C:59 | C:59 | 69.0 | 0.431 | -168.0 | 167.8 | NA | NA | NA | ||||||||||||||
| ASN | D:59 | D:59 | 72.0 | 0.45 | -168.6 | 168.9 | NA | NA | NA | ||||||||||||||
| 1xw5 | 1 | P28161 | 100.0 | 7e-164 |
X-RAY |
2004-11-30 | ASN | A:58 | A:58 | 68.0 | 0.425 | -168.3 | 165.6 | 52.0 | 0.325 | 0.1 |
B:P28161:0.1 |
GSH HOH |
2.974 2.893 |
OD1 ND2 |
N3 O |
||
| ASN | B:58 | B:58 | 71.0 | 0.444 | -163.9 | 170.7 | 55.0 | 0.344 | 0.1 |
A:P28161:0.1 |
GSH HOH |
2.807 2.723 |
OD1 ND2 |
N3 O |
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| 1ykc | 1 | P28161 | 100.0 | 7e-164 |
X-RAY |
2005-01-25 | ASN | A:58 | A:58 | 65.0 | 0.406 | -159.2 | 169.9 | 52.0 | 0.325 | 0.081 |
B:P28161:0.081 |
GDS HOH |
2.815 3.124 |
OD1 CG |
N4 O |
||
| ASN | B:58 | B:58 | 65.0 | 0.406 | -169.0 | 169.1 | 50.0 | 0.312 | 0.094 |
A:P28161:0.094 |
GDS HOH |
2.787 3.026 |
OD1 ND2 |
N4 O |
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| 2ab6 | 1 | P28161 | 100.0 | 7e-164 |
X-RAY |
2005-08-02 | ASN | A:58 | A:58 | 64.0 | 0.4 | -168.4 | 157.4 | 48.0 | 0.3 | 0.1 |
B:P28161:0.1 |
GSM HOH |
2.951 6.429 |
OD1 N |
N3 O |
||
| ASN | B:58 | B:58 | 65.0 | 0.406 | -169.6 | 155.7 | 49.0 | 0.306 | 0.1 |
A:P28161:0.1 |
GSM HOH |
2.965 3.053 |
OD1 CG |
N3 O |
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| ASN | C:58 | C:58 | 66.0 | 0.412 | -172.8 | 155.0 | NA | NA | NA | ||||||||||||||
| ASN | D:58 | D:58 | 64.0 | 0.4 | -170.3 | 159.5 | NA | NA | NA | ||||||||||||||
| 2gtu | 1 | P28161 | 100.0 | 7e-164 |
X-RAY |
1999-03-02 | ASN | A:58 | A:58 | 69.0 | 0.431 | -168.9 | 160.6 | 57.0 | 0.356 | 0.075 |
B:P28161:0.075 |
HOH |
2.855 |
OD1 |
O |
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| ASN | B:58 | B:58 | 70.0 | 0.438 | -161.9 | 166.4 | 56.0 | 0.35 | 0.088 |
A:P28161:0.087 |
HOH |
3.488 |
CB |
O |
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| 3gtu | 1 | P28161 | 100.0 | 7e-164 |
X-RAY |
1999-07-29 | ASN | A:58 | A:58 | 69.0 | 0.431 | -172.3 | 159.9 | 60.0 | 0.375 | 0.056 |
B:P21266:0.056 |
HOH |
2.700 |
ND2 |
O |
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| ASN | C:58 | C:58 | 67.0 | 0.419 | -166.7 | 156.2 | NA | NA | NA | ||||||||||||||
| 3gur | 1 | P28161 | 100.0 | 7e-164 |
X-RAY |
2009-10-27 | ASN | A:58 | A:58 | 71.0 | 0.444 | -166.1 | 167.9 | 53.0 | 0.331 | 0.113 |
B:P28161:0.113 |
BYG HOH |
2.851 2.768 |
OD1 ND2 |
N3 O |
||
| ASN | B:58 | B:58 | 67.0 | 0.419 | -162.6 | 165.5 | 53.0 | 0.331 | 0.088 |
A:P28161:0.087 |
GSH HOH |
3.120 3.029 |
OD1 ND2 |
N3 O |
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| ASN | C:58 | C:58 | 67.0 | 0.419 | -161.0 | 163.8 | NA | NA | NA | ||||||||||||||
| ASN | D:58 | D:58 | 68.0 | 0.425 | -173.6 | 158.8 | NA | NA | NA | ||||||||||||||
| 5hwl | 1 | P28161 | 100.0 | 7e-164 |
X-RAY |
2017-11-08 | ASN | A:58 | A:58 | 64.0 | 0.4 | -168.2 | 172.3 | 50.0 | 0.312 | 0.088 |
B:P28161:0.087 |
GSH NNE HOH |
2.908 7.595 3.087 |
OD1 ND2 ND2 |
N3 CAO O |
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| ASN | B:58 | B:58 | 68.0 | 0.425 | -171.3 | 170.5 | 53.0 | 0.331 | 0.094 |
A:P28161:0.094 |
GSH NNE HOH |
2.980 7.574 3.024 |
OD1 OD1 ND2 |
N3 CAM O |
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| 1hna | 1 | P28161 | 99.54 | 1e-162 |
X-RAY |
1994-01-31 | ASN | A:58 | A:58 | 73.0 | 0.456 | -176.6 | 169.6 | 56.0 | 0.35 | 0.106 |
A:P28161:0.106 |
GDN HOH |
2.904 3.283 |
OD1 ND2 |
N3 O |
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| 1hnb | 1 | P28161 | 99.54 | 1e-162 |
X-RAY |
1994-01-31 | ASN | A:58 | A:58 | 57.0 | 0.356 | 179.5 | 160.2 | 52.0 | 0.325 | 0.031 |
B:P28161:0.031 |
GDN |
2.848 |
ND2 |
OE1 |
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| ASN | B:58 | B:58 | 62.0 | 0.388 | -171.6 | 167.0 | 54.0 | 0.338 | 0.05 |
A:P28161:0.05 |
GDN |
3.028 |
ND2 |
O31 |
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| 1hnc | 1 | P28161 | 99.54 | 1e-162 |
X-RAY |
1994-01-31 | ASN | A:58 | A:58 | 79.0 | 0.494 | -165.4 | 158.0 | 63.0 | 0.394 | 0.1 |
B:P28161:0.1 |
GDN |
3.051 |
OD1 |
CG1 |
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| ASN | B:58 | B:58 | 74.0 | 0.463 | -177.1 | 150.5 | 62.0 | 0.388 | 0.075 |
A:P28161:0.075 |
GDN |
3.101 |
ND2 |
O32 |
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| ASN | C:58 | C:58 | 74.0 | 0.463 | -174.7 | 175.5 | NA | NA | NA | ||||||||||||||
| ASN | D:58 | D:58 | 72.0 | 0.45 | -177.1 | 168.7 | NA | NA | NA | ||||||||||||||
| 1xw6 | 1 | P09488 | 84.4 | 8e-141 |
X-RAY |
2004-12-21 | ASN | A:59 | A:58 | 68.0 | 0.425 | -161.1 | 169.0 | 56.0 | 0.35 | 0.075 |
B:P09488:0.075 |
GSH HOH |
2.875 3.256 |
OD1 ND2 |
N3 O |
||
| ASN | B:59 | B:58 | 70.0 | 0.438 | -160.7 | 172.0 | 58.0 | 0.362 | 0.076 |
A:P09488:0.075 |
GSH HOH |
2.945 3.091 |
OD1 ND2 |
N3 O |
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| ASN | C:59 | C:58 | 71.0 | 0.444 | -160.8 | 172.2 | NA | NA | NA | ||||||||||||||
| ASN | D:59 | D:58 | 68.0 | 0.425 | -162.2 | 169.1 | NA | NA | NA | ||||||||||||||
| 1xwk | 1 | P09488 | 84.4 | 8e-141 |
X-RAY |
2004-12-21 | ASN | A:59 | A:58 | 71.0 | 0.444 | -167.4 | -177.2 | 58.0 | 0.362 | 0.082 |
C:P09488:0.081 |
GDN HOH |
2.703 3.074 |
OD1 ND2 |
N3 O |
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| ASN | B:59 | B:58 | 73.0 | 0.456 | -166.1 | 171.0 | NA | NA | NA | ||||||||||||||
| ASN | C:59 | C:58 | 71.0 | 0.444 | -168.6 | -178.6 | 58.0 | 0.362 | 0.082 |
A:P09488:0.081 |
GDN HOH |
2.740 4.362 |
OD1 ND2 |
N3 O |
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| 1yj6 | 1 | P09488 | 84.4 | 8e-141 |
X-RAY |
2005-02-01 | ASN | A:59 | A:58 | 72.0 | 0.45 | -168.2 | 170.9 | 60.0 | 0.375 | 0.075 |
B:P09488:0.075 |
ZN GSH HOH |
8.393 2.646 3.356 |
OD1 OD1 ND2 |
ZN N3 O |
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| ASN | B:59 | B:58 | 71.0 | 0.444 | -164.3 | 171.2 | 56.0 | 0.35 | 0.094 |
A:P09488:0.094 |
ZN GSH HOH |
8.416 2.642 5.473 |
OD1 OD1 ND2 |
ZN N3 O |
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| ASN | C:59 | C:58 | 73.0 | 0.456 | -166.8 | 166.9 | NA | NA | NA | ||||||||||||||
| 2f3m | 1 | P09488 | 84.4 | 8e-141 |
X-RAY |
2006-04-25 | ASN | A:59 | A:58 | 70.0 | 0.438 | -165.5 | 173.3 | 58.0 | 0.362 | 0.076 |
B:P09488:0.075 |
GTD HOH |
3.037 3.674 |
OD1 CB |
N3 O |
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| ASN | B:59 | B:58 | 71.0 | 0.444 | -162.5 | 174.1 | 59.0 | 0.369 | 0.075 |
A:P09488:0.075 |
GTD HOH |
2.840 3.242 |
OD1 CB |
N3 O |
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| ASN | C:59 | C:58 | 69.0 | 0.431 | -164.6 | 168.9 | NA | NA | NA | ||||||||||||||
| ASN | D:59 | D:58 | 70.0 | 0.438 | -163.2 | 169.8 | NA | NA | NA | ||||||||||||||
| ASN | E:59 | E:58 | 69.0 | 0.431 | -164.9 | 174.3 | NA | NA | NA | ||||||||||||||
| ASN | F:59 | F:58 | 72.0 | 0.45 | -160.7 | 174.7 | NA | NA | NA | ||||||||||||||
| 7beu | 1 | P09488 | 84.4 | 8e-141 |
X-RAY |
2022-01-12 | ASN | A:59 | A:58 | 74.0 | 0.463 | -171.4 | 161.7 | 61.0 | 0.381 | 0.082 |
D:P09488:0.081 |
HOH |
3.314 |
CB |
O |
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| ASN | B:59 | B:58 | 75.0 | 0.469 | -166.0 | 160.3 | NA | NA | NA | ||||||||||||||
| ASN | C:59 | C:58 | 70.0 | 0.438 | -171.4 | 160.9 | NA | NA | NA | ||||||||||||||
| ASN | D:59 | D:58 | 73.0 | 0.456 | -172.5 | 160.1 | 59.0 | 0.369 | 0.087 |
A:P09488:0.087 |
HOH |
3.034 |
ND2 |
O |
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| 2dc5 | 1 | 30354091 | 83.41 | 1e-140 |
X-RAY |
2006-06-28 | ASN | A:66 | A:66 | 69.0 | 0.431 | -167.1 | 170.0 | 65.0 | 0.406 | 0.025 |
B:30354091:0.025 |
HOH |
2.715 |
ND2 |
O |
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| ASN | B:66 | B:66 | 74.0 | 0.463 | -170.1 | 168.7 | 67.0 | 0.419 | 0.044 |
A:30354091:0.044 |
HOH |
2.985 |
ND2 |
O |
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| 1gtu | 1 | P09488 | 84.33 | 6e-140 |
X-RAY |
1999-02-02 | ASN | A:58 | A:58 | 66.0 | 0.412 | -168.3 | 162.8 | 55.0 | 0.344 | 0.068 |
B:P09488:0.069 |
HOH |
3.242 |
CB |
O |
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| ASN | B:58 | B:58 | 70.0 | 0.438 | -171.6 | 165.9 | 57.0 | 0.356 | 0.082 |
A:P09488:0.081 |
HOH |
3.101 |
ND2 |
O |
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| ASN | C:58 | C:58 | 72.0 | 0.45 | -167.5 | 159.9 | NA | NA | NA | ||||||||||||||
| ASN | D:58 | D:58 | 70.0 | 0.438 | -167.0 | 166.1 | NA | NA | NA | ||||||||||||||
| 4gtu | 1 | Q03013 | 83.33 | 7e-139 |
X-RAY |
2000-01-14 | ASN | A:58 | A:58 | 73.0 | 0.456 | -143.9 | 160.9 | 60.0 | 0.375 | 0.081 |
B:Q03013:0.081 |
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| ASN | B:58 | B:58 | 66.0 | 0.412 | 173.1 | 161.9 | 62.0 | 0.388 | 0.024 |
A:Q03013:0.025 |
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| ASN | C:58 | C:58 | 67.0 | 0.419 | -156.8 | 162.9 | NA | NA | NA | ||||||||||||||
| ASN | D:58 | D:58 | 62.0 | 0.388 | -175.2 | 153.3 | NA | NA | NA | ||||||||||||||
| ASN | E:58 | E:58 | 56.0 | 0.35 | -163.4 | 145.7 | NA | NA | NA | ||||||||||||||
| ASN | F:58 | F:58 | 70.0 | 0.438 | -167.3 | 157.0 | NA | NA | NA | ||||||||||||||
| ASN | G:58 | G:58 | 72.0 | 0.45 | -176.0 | 163.9 | NA | NA | NA | ||||||||||||||
| ASN | H:58 | H:58 | 72.0 | 0.45 | -172.8 | 163.3 | NA | NA | NA | ||||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p28161-f1 | 1 | P28161 | 100.0 | 3e-165 | ASN | A:59 | A:59 | 75.0 | 0.469 | -154.0 | 172.0 | ||
| af-p09488-f1 | 1 | P09488 | 84.4 | 3e-141 | ASN | A:59 | A:59 | 75.0 | 0.469 | -153.5 | 171.6 | ||
| af-q03013-f1 | 1 | Q03013 | 83.03 | 6e-140 | ASN | A:59 | A:59 | 72.0 | 0.45 | -153.0 | 171.2 | ||
| af-p46439-f1 | 1 | P46439 | 81.19 | 6e-134 | ASN | A:59 | A:59 | 74.0 | 0.463 | -154.3 | 171.9 | ||