Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 110211933 . A C CCDS808.1:NM_000848.3:c.199Act>Cct_NP_000839.1:p.67T>P Homo sapiens glutathione S-transferase mu 2 (GSTM2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2c4j 1 P28161 99.54 3e-164 X-RAY
 2005-10-26 THR A:67 A:67 124.0 0.886 T -81.9 -20.9 116.0 0.829 0.057 B:P28161:0.057
 HOH
 3.031
 N
 O
THR B:67 B:67 125.0 0.893 T -90.7 -11.5 118.0 0.843 0.05 A:P28161:0.05
 HOH
 3.360
 O
 O
THR C:67 C:67 123.0 0.879 T -65.8 -21.6 NA NA NA
THR D:67 D:67 133.0 0.95 T -79.4 -10.0 NA NA NA
1xw5 1 P28161 100.0 7e-164 X-RAY
 2004-11-30 THR A:66 A:66 131.0 0.936 T -76.1 -9.5 119.0 0.85 0.086 B:P28161:0.086
 HOH
 2.799
 N
 O
THR B:66 B:66 129.0 0.921 T -75.3 -11.4 118.0 0.843 0.078 A:P28161:0.079
 HOH
 2.637
 N
 O
1ykc 1 P28161 100.0 7e-164 X-RAY
 2005-01-25 THR A:66 A:66 130.0 0.929 T -76.2 -18.3 112.0 0.8 0.129 B:P28161:0.129
 HOH
 2.606
 N
 O
THR B:66 B:66 126.0 0.9 T -79.3 -17.3 113.0 0.807 0.093 A:P28161:0.093
 HOH
 2.971
 O
 O
2ab6 1 P28161 100.0 7e-164 X-RAY
 2005-08-02 THR A:66 A:66 127.0 0.907 T -68.4 -35.6 116.0 0.829 0.078 B:P28161:0.079
 HOH
 8.777
 O
 O
THR B:66 B:66 130.0 0.929 T -73.3 -32.2 118.0 0.843 0.086 A:P28161:0.086
 HOH
 4.985
 O
 O
THR C:66 C:66 130.0 0.929 T -71.9 -31.2 NA NA NA
THR D:66 D:66 130.0 0.929 T -69.8 -32.7 NA NA NA
2gtu 1 P28161 100.0 7e-164 X-RAY
 1999-03-02 THR A:66 A:66 126.0 0.9 T -73.7 -9.1 108.0 0.771 0.129 B:P28161:0.129
 HOH
 7.700
 O
 O
THR B:66 B:66 128.0 0.914 T -81.2 -16.3 113.0 0.807 0.107 A:P28161:0.107
 HOH
 7.627
 O
 O
3gtu 1 P28161 100.0 7e-164 X-RAY
 1999-07-29 THR A:66 A:66 123.0 0.879 T -87.7 -10.9 123.0 0.879 0.0 HOH
 9.523
 O
 O
THR C:66 C:66 123.0 0.879 T -85.1 -16.7 NA NA NA
3gur 1 P28161 100.0 7e-164 X-RAY
 2009-10-27 THR A:66 A:66 122.0 0.871 T -69.9 -21.2 122.0 0.871 0.0 HOH
 3.708
 O
 O
THR B:66 B:66 124.0 0.886 T -86.4 5.0 124.0 0.886 0.0 HOH
 4.446
 O
 O
THR C:66 C:66 126.0 0.9 T -101.5 -11.7 NA NA NA
THR D:66 D:66 125.0 0.893 T -75.5 -12.5 NA NA NA
5hwl 1 P28161 100.0 7e-164 X-RAY
 2017-11-08 THR A:66 A:66 93.0 NA T -88.1 -1.3 87.0 NA NA B:P28161:NA
 HOH
 5.504
 O
 O
THR B:66 B:66 90.0 NA T -82.4 -17.4 90.0 NA NA HOH
 8.072
 O
 O
1hna 1 P28161 99.54 1e-162 X-RAY
 1994-01-31 THR A:66 A:66 133.0 0.95 T -88.2 -12.5 131.0 0.936 0.014 A:P28161:0.014
 HOH
 3.097
 O
 O
1hnb 1 P28161 99.54 1e-162 X-RAY
 1994-01-31 THR A:66 A:66 121.0 0.864 S -97.0 44.4 102.0 0.729 0.135 B:P28161:0.136
THR B:66 B:66 120.0 0.857 T -96.3 -46.4 117.0 0.836 0.021 A:P28161:0.021
1hnc 1 P28161 99.54 1e-162 X-RAY
 1994-01-31 THR A:66 A:66 124.0 0.886 T -90.7 -18.3 124.0 0.886 0.0
THR B:66 B:66 127.0 0.907 T -110.8 7.3 111.0 0.793 0.114 A:P28161:0.114
THR C:66 C:66 129.0 0.921 T -113.5 26.0 NA NA NA
THR D:66 D:66 131.0 0.936 T -92.0 12.3 NA NA NA
1xw6 1 P09488 84.4 8e-141 X-RAY
 2004-12-21 ALA A:67 A:66 95.0 0.826 T -71.3 -22.1 95.0 0.826 0.0 HOH
 2.634
 O
 O
ALA B:67 B:66 92.0 0.8 T -71.5 -23.8 92.0 0.8 0.0 HOH
 2.620
 O
 O
ALA C:67 C:66 94.0 0.817 T -72.6 -23.7 NA NA NA
ALA D:67 D:66 93.0 0.809 T -70.9 -25.5 NA NA NA
1xwk 1 P09488 84.4 8e-141 X-RAY
 2004-12-21 ALA A:67 A:66 94.0 0.817 T -91.7 -9.4 94.0 0.817 0.0 HOH
 4.399
 O
 O
ALA B:67 B:66 91.0 0.791 T -76.0 -19.8 NA NA NA
ALA C:67 C:66 92.0 0.8 T -83.2 -14.0 92.0 0.8 0.0 HOH
 3.819
 O
 O
1yj6 1 P09488 84.4 8e-141 X-RAY
 2005-02-01 ALA A:67 A:66 90.0 0.783 T -91.1 -6.8 90.0 0.783 0.0 HOH
 4.081
 O
 O
ALA B:67 B:66 91.0 0.791 T -85.7 -11.0 91.0 0.791 0.0 HOH
 4.091
 O
 O
ALA C:67 C:66 91.0 0.791 T -82.8 -13.9 NA NA NA
2f3m 1 P09488 84.4 8e-141 X-RAY
 2006-04-25 ALA A:67 A:66 91.0 0.791 T -69.4 -32.0 91.0 0.791 0.0
ALA B:67 B:66 88.0 0.765 T -70.5 -32.1 87.0 0.757 0.008 A:P09488:0.009
ALA C:67 C:66 89.0 0.774 T -63.8 -35.6 NA NA NA
ALA D:67 D:66 88.0 0.765 T -64.8 -36.0 NA NA NA
ALA E:67 E:66 89.0 0.774 T -67.1 -34.9 NA NA NA
ALA F:67 F:66 90.0 0.783 T -68.6 -32.9 NA NA NA
7beu 1 P09488 84.4 8e-141 X-RAY
 2022-01-12 ALA A:67 A:66 93.0 0.809 T -75.0 -14.5 93.0 0.809 0.0 HOH
 2.988
 O
 O
ALA B:67 B:66 98.0 0.852 T -74.7 -12.7 NA NA NA
ALA C:67 C:66 92.0 0.8 T -75.0 -15.5 NA NA NA
ALA D:67 D:66 90.0 0.783 T -79.3 -12.5 90.0 0.783 0.0 HOH
 4.059
 O
 O
2dc5 1 30354091 83.41 1e-140 X-RAY
 2006-06-28 SER A:74 A:74 100.0 0.87 T -78.3 -9.7 95.0 0.826 0.044 B:30354091:0.043
 HOH
 3.095
 N
 O
SER B:74 B:74 104.0 0.904 T -74.9 -8.9 98.0 0.852 0.052 A:30354091:0.052
 HOH
 2.781
 O
 O
1gtu 1 P09488 84.33 6e-140 X-RAY
 1999-02-02 ALA A:66 A:66 91.0 0.791 T -89.7 2.9 91.0 0.791 0.0 HOH
 9.033
 O
 O
ALA B:66 B:66 92.0 0.8 T -91.2 -2.9 92.0 0.8 0.0
ALA C:66 C:66 94.0 0.817 T -76.2 -11.6 NA NA NA
ALA D:66 D:66 94.0 0.817 T -80.0 -17.7 NA NA NA
4gtu 1 Q03013 83.33 7e-139 X-RAY
 2000-01-14 ALA A:66 A:66 88.0 0.765 S -110.6 37.2 88.0 0.765 0.0
ALA B:66 B:66 103.0 0.896 S -82.3 31.6 103.0 0.896 0.0
ALA C:66 C:66 91.0 0.791 T -113.6 -21.5 NA NA NA
ALA D:66 D:66 94.0 0.817 T -99.6 -3.9 NA NA NA
ALA E:66 E:66 93.0 0.809 T -88.6 -5.7 NA NA NA
ALA F:66 F:66 89.0 0.774 T -93.9 -5.1 NA NA NA
ALA G:66 G:66 93.0 0.809 T -101.6 2.5 NA NA NA
ALA H:66 H:66 95.0 0.826 T -88.0 -25.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p28161-f1 1 P28161 100.0 3e-165 THR A:67 A:67 120.0 0.857 T -83.3 -19.5
af-p09488-f1 1 P09488 84.4 3e-141 ALA A:67 A:67 85.0 0.739 T -78.6 -21.6
af-q03013-f1 1 Q03013 83.03 6e-140 ALA A:67 A:67 86.0 0.748 T -78.7 -20.1
af-p46439-f1 1 P46439 81.19 6e-134 ALA A:67 A:67 88.0 0.765 T -78.9 -18.7