Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 110212151 . C A CCDS808.1:NM_000848.3:c.318gaC>gaA_NP_000839.1:p.106D>E Homo sapiens glutathione S-transferase mu 2 (GSTM2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2c4j 1 P28161 99.54 3e-164 X-RAY
 2005-10-26 ASP A:106 A:106 81.0 0.54 H -59.7 -45.8 52.0 0.347 0.193 B:P28161:0.193
 GSO
GSO
HOH
 9.999
2.899
2.534
 N
OD2
OD2
 OT1
N
O
ASP B:106 B:106 99.0 0.66 H -60.6 -44.3 70.0 0.467 0.193 A:P28161:0.193
 GSO
HOH
 2.916
2.657
 OD2
OD2
 N
O
ASP C:106 C:106 84.0 0.56 H -58.7 -47.9 NA NA NA
ASP D:106 D:106 90.0 0.6 H -57.3 -46.2 NA NA NA
1xw5 1 P28161 100.0 7e-164 X-RAY
 2004-11-30 ASP A:105 A:105 82.0 0.547 H -63.2 -44.2 51.0 0.34 0.207 B:P28161:0.207
 GSH
HOH
 2.919
2.639
 OD2
O
 N1
O
ASP B:105 B:105 82.0 0.547 H -65.5 -45.4 49.0 0.327 0.22 A:P28161:0.22
 GSH
HOH
 2.855
2.695
 OD2
OD2
 N1
O
1ykc 1 P28161 100.0 7e-164 X-RAY
 2005-01-25 ASP A:105 A:105 89.0 0.593 H -62.3 -45.5 54.0 0.36 0.233 B:P28161:0.233
 GDS
GDS
HOH
 8.630
2.972
2.647
 O
OD2
O
 OE4
N6
O
ASP B:105 B:105 87.0 0.58 H -60.6 -43.5 54.0 0.36 0.22 A:P28161:0.22
 GDS
GDS
HOH
 2.930
8.821
2.732
 OD2
O
O
 N6
OE4
O
2ab6 1 P28161 100.0 7e-164 X-RAY
 2005-08-02 ASP A:105 A:105 90.0 0.6 H -60.6 -38.7 60.0 0.4 0.2 B:P28161:0.2
 GSM
HOH
 3.110
3.365
 OD2
OD2
 N1
O
ASP B:105 B:105 90.0 0.6 H -62.1 -42.6 58.0 0.387 0.213 A:P28161:0.213
 GSM
HOH
 2.883
4.856
 OD2
C
 N1
O
ASP C:105 C:105 89.0 0.593 H -58.9 -38.5 NA NA NA
ASP D:105 D:105 93.0 0.62 H -60.5 -40.2 NA NA NA
2gtu 1 P28161 100.0 7e-164 X-RAY
 1999-03-02 ASP A:105 A:105 94.0 0.627 H -65.7 -44.4 69.0 0.46 0.167 B:P28161:0.167
 HOH
 5.788
 O
 O
ASP B:105 B:105 95.0 0.633 H -65.9 -45.5 68.0 0.453 0.18 A:P28161:0.18
 HOH
 3.918
 OD2
 O
3gtu 1 P28161 100.0 7e-164 X-RAY
 1999-07-29 ASP A:105 A:105 100.0 0.667 H -56.4 -55.0 77.0 0.513 0.154 B:P21266:0.153
 HOH
 4.929
 OD2
 O
ASP C:105 C:105 97.0 0.647 H -54.7 -53.6 NA NA NA
3gur 1 P28161 100.0 7e-164 X-RAY
 2009-10-27 ASP A:105 A:105 78.0 0.52 H -64.3 -45.6 50.0 0.333 0.187 B:P28161:0.187
 BYG
GSH
HOH
 8.545
2.964
3.429
 O
OD2
OD1
 OA4
N1
O
ASP B:105 B:105 77.0 0.513 H -58.6 -43.4 49.0 0.327 0.186 A:P28161:0.187
 BYG
GSH
HOH
 3.350
9.914
2.546
 OD2
N
OD2
 N1
O11
O
ASP C:105 C:105 76.0 0.507 H -57.5 -54.5 NA NA NA
ASP D:105 D:105 75.0 0.5 H -55.3 -48.7 NA NA NA
5hwl 1 P28161 100.0 7e-164 X-RAY
 2017-11-08 ASP A:105 A:105 102.0 0.68 H -59.1 -43.6 71.0 0.473 0.207 B:P28161:0.207
 GSH
NNE
HOH
 2.851
3.006
2.713
 OD1
OD1
OD1
 N1
NAV
O
ASP B:105 B:105 95.0 0.633 H -59.6 -44.8 65.0 0.433 0.2 A:P28161:0.2
 GSH
NNE
HOH
 2.902
2.948
2.692
 OD1
OD1
OD2
 N1
CAP
O
1hna 1 P28161 99.54 1e-162 X-RAY
 1994-01-31 ASP A:105 A:105 96.0 0.64 H -60.8 -45.5 66.0 0.44 0.2 A:P28161:0.2
 GDN
GDN
HOH
 9.915
2.836
3.040
 N
OD2
OD1
 O11
N1
O
1hnb 1 P28161 99.54 1e-162 X-RAY
 1994-01-31 ASP A:105 A:105 78.0 0.52 H -57.2 -46.0 55.0 0.367 0.153 B:P28161:0.153
 GDN
GDN
 9.560
2.972
 N
OD2
 N1
O12
ASP B:105 B:105 98.0 0.653 H -57.4 -56.4 75.0 0.5 0.153 A:P28161:0.153
 GDN
GDN
 3.195
9.956
 OD2
N
 N1
O11
1hnc 1 P28161 99.54 1e-162 X-RAY
 1994-01-31 ASP A:105 A:105 76.0 0.507 H -59.1 -48.2 50.0 0.333 0.174 B:P28161:0.173
 GDN
 3.141
 OD2
 N1
ASP B:105 B:105 93.0 0.62 H -59.9 -51.9 69.0 0.46 0.16 A:P28161:0.16
 GDN
GDN
 2.888
9.901
 OD2
N
 N1
N1
ASP C:105 C:105 83.0 0.553 H -54.2 -38.7 NA NA NA
ASP D:105 D:105 102.0 0.68 H -67.6 -56.5 NA NA NA
1xw6 1 P09488 84.4 8e-141 X-RAY
 2004-12-21 ASP A:106 A:105 88.0 0.587 H -59.3 -52.5 58.0 0.387 0.2 B:P09488:0.2
 GSH
GSH
HOH
 9.322
2.681
2.637
 N
OD2
OD2
 N1
N1
O
ASP B:106 B:105 89.0 0.593 H -59.7 -51.4 59.0 0.393 0.2 A:P09488:0.2
 GSH
GSH
HOH
 3.092
9.688
2.620
 OD2
N
OD2
 N1
O11
O
ASP C:106 C:105 89.0 0.593 H -60.8 -51.1 NA NA NA
ASP D:106 D:105 88.0 0.587 H -60.7 -51.2 NA NA NA
1xwk 1 P09488 84.4 8e-141 X-RAY
 2004-12-21 ASP A:106 A:105 88.0 0.587 H -69.0 -66.0 55.0 0.367 0.22 C:P09488:0.22
 GDN
GDN
HOH
 8.167
2.928
4.001
 O
OD2
OD1
 O2A
N1
O
ASP B:106 B:105 88.0 0.587 H -63.3 -61.4 NA NA NA
ASP C:106 C:105 90.0 0.6 H -69.2 -63.1 53.0 0.353 0.247 A:P09488:0.247
 GDN
GDN
HOH
 2.711
8.206
5.185
 OD2
O
OD2
 N1
O2A
O
1yj6 1 P09488 84.4 8e-141 X-RAY
 2005-02-01 ASP A:106 A:105 82.0 0.547 H -65.9 -55.7 49.0 0.327 0.22 B:P09488:0.22
 GSH
ZN
GSH
HOH
 9.643
9.983
3.124
4.719
 N
OD2
OD2
OD2
 N1
ZN
N1
O
ASP B:106 B:105 76.0 0.507 H -66.9 -56.6 46.0 0.307 0.2 A:P09488:0.2
 GSH
GSH
HOH
 3.021
9.282
4.334
 OD2
N
OD2
 N1
N1
O
ASP C:106 C:105 84.0 0.56 H -62.9 -52.7 NA NA NA
2f3m 1 P09488 84.4 8e-141 X-RAY
 2006-04-25 ASP A:106 A:105 68.0 0.453 H -70.5 -53.8 40.0 0.267 0.186 B:P09488:0.187
 GTD
GTD
HOH
 7.490
3.161
6.541
 O
OD2
OD2
 O41
N1
O
ASP B:106 B:105 71.0 0.473 H -65.1 -54.8 34.0 0.227 0.246 A:P09488:0.247
 GTD
GTD
HOH
 2.908
7.554
3.972
 OD2
O
OD2
 N1
O41
O
ASP C:106 C:105 75.0 0.5 H -71.0 -52.5 NA NA NA
ASP D:106 D:105 78.0 0.52 H -66.4 -54.5 NA NA NA
ASP E:106 E:105 72.0 0.48 H -68.3 -51.7 NA NA NA
ASP F:106 F:105 66.0 0.44 H -64.3 -54.3 NA NA NA
7beu 1 P09488 84.4 8e-141 X-RAY
 2022-01-12 ASP A:106 A:105 88.0 0.587 H -54.5 -51.8 54.0 0.36 0.227 D:P09488:0.227
 HOH
 2.656
 OD2
 O
ASP B:106 B:105 86.0 0.573 H -59.5 -48.4 NA NA NA
ASP C:106 C:105 90.0 0.6 H -61.1 -48.0 NA NA NA
ASP D:106 D:105 73.0 0.487 H -54.9 -49.4 44.0 0.293 0.194 A:P09488:0.193
 HOH
 4.904
 OD1
 O
2dc5 1 30354091 83.41 1e-140 X-RAY
 2006-06-28 ASP A:113 A:113 94.0 0.627 H -59.2 -48.8 48.0 0.32 0.307 B:30354091:0.307
 HOH
 2.732
 O
 O
ASP B:113 B:113 96.0 0.64 H -59.3 -44.7 56.0 0.373 0.267 A:30354091:0.267
 HOH
 3.602
 OD2
 O
1gtu 1 P09488 84.33 6e-140 X-RAY
 1999-02-02 ASP A:105 A:105 83.0 0.553 H -65.2 -58.2 49.0 0.327 0.226 B:P09488:0.227
 HOH
 4.157
 OD1
 O
ASP B:105 B:105 75.0 0.5 H -62.2 -59.6 43.0 0.287 0.213 A:P09488:0.213
 HOH
 2.726
 OD1
 O
ASP C:105 C:105 85.0 0.567 H -60.3 -56.2 NA NA NA
ASP D:105 D:105 81.0 0.54 H -59.1 -59.7 NA NA NA
4gtu 1 Q03013 83.33 7e-139 X-RAY
 2000-01-14 ASP A:105 A:105 72.0 0.48 H -67.5 -52.9 49.0 0.327 0.153 B:Q03013:0.153
ASP B:105 B:105 74.0 0.493 H -67.2 -44.1 50.0 0.333 0.16 A:Q03013:0.16
ASP C:105 C:105 90.0 0.6 H -64.4 -53.3 NA NA NA
ASP D:105 D:105 75.0 0.5 H -56.4 -38.0 NA NA NA
ASP E:105 E:105 70.0 0.467 H -44.5 -56.1 NA NA NA
ASP F:105 F:105 64.0 0.427 H -54.0 -38.2 NA NA NA
ASP G:105 G:105 64.0 0.427 H -59.1 -36.2 NA NA NA
ASP H:105 H:105 48.0 0.32 H -65.9 -40.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p28161-f1 1 P28161 100.0 3e-165 ASP A:106 A:106 94.0 0.627 H -59.9 -50.5
af-p09488-f1 1 P09488 84.4 3e-141 ASP A:106 A:106 102.0 0.68 H -57.3 -45.2
af-q03013-f1 1 Q03013 83.03 6e-140 ASP A:106 A:106 95.0 0.633 H -60.1 -44.9
af-p46439-f1 1 P46439 81.19 6e-134 ASP A:106 A:106 96.0 0.64 H -59.0 -48.8