Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 110213993 . C A CCDS808.1:NM_000848.3:c.445Ctt>Att_NP_000839.1:p.149L>I Homo sapiens glutathione S-transferase mu 2 (GSTM2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2c4j 1 P28161 99.54 3e-164 X-RAY
 2005-10-26 LEU A:149 A:149 9.0 0.053 T -100.0 4.6 9.0 0.053 0.0 HOH
 2.680
 O
 O
LEU B:149 B:149 7.0 0.041 T -101.4 9.2 7.0 0.041 0.0 HOH
 2.840
 O
 O
LEU C:149 C:149 13.0 0.076 T -100.1 5.5 NA NA NA
LEU D:149 D:149 13.0 0.076 T -101.7 7.0 NA NA NA
1xw5 1 P28161 100.0 7e-164 X-RAY
 2004-11-30 LEU A:148 A:148 10.0 0.059 T -101.7 -2.0 10.0 0.059 0.0 HOH
 2.669
 O
 O
LEU B:148 B:148 6.0 0.035 T -104.6 -7.3 6.0 0.035 0.0 HOH
 2.652
 O
 O
1ykc 1 P28161 100.0 7e-164 X-RAY
 2005-01-25 LEU A:148 A:148 6.0 0.035 T -110.4 8.6 6.0 0.035 0.0 HOH
 2.885
 O
 O
LEU B:148 B:148 6.0 0.035 T -106.0 5.8 6.0 0.035 0.0 HOH
 2.660
 N
 O
2ab6 1 P28161 100.0 7e-164 X-RAY
 2005-08-02 LEU A:148 A:148 8.0 0.047 T -94.1 -0.7 8.0 0.047 0.0 HOH
 3.592
 CD1
 O
LEU B:148 B:148 9.0 0.053 T -92.9 -4.5 9.0 0.053 0.0 HOH
 5.926
 O
 O
LEU C:148 C:148 9.0 0.053 T -94.4 -4.8 NA NA NA
LEU D:148 D:148 9.0 0.053 T -90.6 -5.6 NA NA NA
2gtu 1 P28161 100.0 7e-164 X-RAY
 1999-03-02 LEU A:148 A:148 6.0 0.035 T -100.8 21.1 6.0 0.035 0.0 HOH
 2.908
 N
 O
LEU B:148 B:148 4.0 0.024 T -108.8 31.0 4.0 0.024 0.0 HOH
 2.992
 N
 O
3gtu 1 P28161 100.0 7e-164 X-RAY
 1999-07-29 LEU A:148 A:148 4.0 0.024 T -97.6 21.3 4.0 0.024 0.0
LEU C:148 C:148 5.0 0.029 T -92.6 17.5 NA NA NA
3gur 1 P28161 100.0 7e-164 X-RAY
 2009-10-27 LEU A:148 A:148 9.0 0.053 T -104.5 4.5 9.0 0.053 0.0 HOH
 2.975
 N
 O
LEU B:148 B:148 8.0 0.047 T -104.3 13.0 8.0 0.047 0.0 HOH
 2.824
 N
 O
LEU C:148 C:148 7.0 0.041 T -96.8 -11.6 NA NA NA
LEU D:148 D:148 6.0 0.035 T -100.7 11.5 NA NA NA
5hwl 1 P28161 100.0 7e-164 X-RAY
 2017-11-08 LEU A:148 A:148 16.0 0.094 T -92.8 -0.6 16.0 0.094 0.0 HOH
 2.781
 O
 O
LEU B:148 B:148 9.0 0.053 T -94.3 -6.4 9.0 0.053 0.0 HOH
 2.986
 N
 O
1hna 1 P28161 99.54 1e-162 X-RAY
 1994-01-31 LEU A:148 A:148 10.0 0.059 T -100.1 -4.2 10.0 0.059 0.0 HOH
 2.870
 N
 O
1hnb 1 P28161 99.54 1e-162 X-RAY
 1994-01-31 LEU A:148 A:148 13.0 0.076 T -86.6 -38.5 13.0 0.076 0.0
LEU B:148 B:148 11.0 0.065 T -74.7 -27.0 11.0 0.065 0.0
1hnc 1 P28161 99.54 1e-162 X-RAY
 1994-01-31 LEU A:148 A:148 3.0 0.018 B -115.4 28.6 3.0 0.018 0.0
LEU B:148 B:148 4.0 0.024 T -120.3 36.0 4.0 0.024 0.0
LEU C:148 C:148 13.0 0.076 T 90.3 2.9 NA NA NA
LEU D:148 D:148 9.0 0.053 T -99.0 -11.3 NA NA NA
1xw6 1 P09488 84.4 8e-141 X-RAY
 2004-12-21 ALA A:149 A:148 3.0 0.026 S -85.8 -17.7 3.0 0.026 0.0 HOH
 2.888
 N
 O
ALA B:149 B:148 4.0 0.035 S -85.9 -16.5 4.0 0.035 0.0 HOH
 2.693
 N
 O
ALA C:149 C:148 3.0 0.026 S -87.2 -16.2 NA NA NA
ALA D:149 D:148 4.0 0.035 S -85.3 -16.6 NA NA NA
1xwk 1 P09488 84.4 8e-141 X-RAY
 2004-12-21 ALA A:149 A:148 4.0 0.035 S -65.9 -38.8 4.0 0.035 0.0 HOH
 6.204
 O
 O
ALA B:149 B:148 4.0 0.035 S -76.0 -28.5 NA NA NA
ALA C:149 C:148 4.0 0.035 S -66.6 -33.7 4.0 0.035 0.0 HOH
 8.048
 O
 O
1yj6 1 P09488 84.4 8e-141 X-RAY
 2005-02-01 ALA A:149 A:148 4.0 0.035 S -64.7 -37.9 4.0 0.035 0.0 HOH
 4.485
 O
 O
ALA B:149 B:148 3.0 0.026 S -67.2 -35.2 3.0 0.026 0.0 HOH
 8.410
 O
 O
ALA C:149 C:148 4.0 0.035 S -66.2 -35.4 NA NA NA
2f3m 1 P09488 84.4 8e-141 X-RAY
 2006-04-25 ALA A:149 A:148 4.0 0.035 S -71.8 -32.2 4.0 0.035 0.0 HOH
 6.736
 CB
 O
ALA B:149 B:148 4.0 0.035 S -73.1 -30.6 4.0 0.035 0.0 HOH
 2.599
 CB
 O
ALA C:149 C:148 4.0 0.035 S -73.9 -32.1 NA NA NA
ALA D:149 D:148 3.0 0.026 S -73.4 -32.1 NA NA NA
ALA E:149 E:148 4.0 0.035 S -71.7 -33.4 NA NA NA
ALA F:149 F:148 4.0 0.035 S -72.9 -31.7 NA NA NA
7beu 1 P09488 84.4 8e-141 X-RAY
 2022-01-12 ALA A:149 A:148 4.0 0.035 T -85.9 -11.2 4.0 0.035 0.0 HOH
 2.653
 O
 O
ALA B:149 B:148 1.0 0.009 T -87.7 -9.8 NA NA NA
ALA C:149 C:148 4.0 0.035 T -88.1 -13.4 NA NA NA
ALA D:149 D:148 3.0 0.026 T -85.1 -14.8 3.0 0.026 0.0 HOH
 2.586
 O
 O
2dc5 1 30354091 83.41 1e-140 X-RAY
 2006-06-28 ALA A:156 A:156 4.0 0.035 T -89.3 -15.0 4.0 0.035 0.0 HOH
 2.707
 O
 O
ALA B:156 B:156 3.0 0.026 T -90.3 -12.7 3.0 0.026 0.0 HOH
 2.621
 O
 O
1gtu 1 P09488 84.33 6e-140 X-RAY
 1999-02-02 ALA A:148 A:148 3.0 0.026 T -85.4 -15.5 3.0 0.026 0.0
ALA B:148 B:148 3.0 0.026 T -77.8 -20.1 3.0 0.026 0.0
ALA C:148 C:148 4.0 0.035 S -83.4 -22.7 NA NA NA
ALA D:148 D:148 2.0 0.017 T -80.9 -10.4 NA NA NA
4gtu 1 Q03013 83.33 7e-139 X-RAY
 2000-01-14 VAL A:148 A:148 5.0 0.032 T -86.1 -37.3 5.0 0.032 0.0
VAL B:148 B:148 10.0 0.065 T -106.1 -29.6 10.0 0.065 0.0
VAL C:148 C:148 6.0 0.039 T -66.8 -23.5 NA NA NA
VAL D:148 D:148 3.0 0.019 T -97.6 -21.5 NA NA NA
VAL E:148 E:148 3.0 0.019 T -81.5 -32.6 NA NA NA
VAL F:148 F:148 2.0 0.013 T -97.0 16.9 NA NA NA
VAL G:148 G:148 6.0 0.039 T -78.7 -38.3 NA NA NA
VAL H:148 H:148 4.0 0.026 T -79.1 -29.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p28161-f1 1 P28161 100.0 3e-165 LEU A:149 A:149 9.0 0.053 T -98.3 -6.6
af-p09488-f1 1 P09488 84.4 3e-141 ALA A:149 A:149 3.0 0.026 S -75.6 -36.7
af-q03013-f1 1 Q03013 83.03 6e-140 VAL A:149 A:149 6.0 0.039 S -91.2 -30.9
af-p46439-f1 1 P46439 81.19 6e-134 ALA A:149 A:149 3.0 0.026 S -77.2 -33.5