Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 110214179 | . | C | A | CCDS808.1:NM_000848.3:c.541Ctg>Atg_NP_000839.1:p.181L>M | Homo sapiens glutathione S-transferase mu 2 (GSTM2), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 2c4j | 1 | P28161 | 99.54 | 3e-164 |
X-RAY |
2005-10-26 | LEU | A:181 | A:181 | 0.0 | 0.0 | H | -70.9 | -41.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.880 |
N |
O |
||
| LEU | B:181 | B:181 | 0.0 | 0.0 | H | -71.5 | -41.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.846 |
N |
O |
|||||||||
| LEU | C:181 | C:181 | 0.0 | 0.0 | H | -71.4 | -45.2 | NA | NA | NA | |||||||||||||
| LEU | D:181 | D:181 | 0.0 | 0.0 | H | -76.7 | -39.3 | NA | NA | NA | |||||||||||||
| 1xw5 | 1 | P28161 | 100.0 | 7e-164 |
X-RAY |
2004-11-30 | LEU | A:180 | A:180 | 0.0 | 0.0 | H | -72.6 | -37.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.809 |
N |
O |
||
| LEU | B:180 | B:180 | 0.0 | 0.0 | H | -75.7 | -33.8 | 0.0 | 0.0 | 0.0 |
HOH |
4.672 |
N |
O |
|||||||||
| 1ykc | 1 | P28161 | 100.0 | 7e-164 |
X-RAY |
2005-01-25 | LEU | A:180 | A:180 | 0.0 | 0.0 | H | -73.9 | -29.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.801 |
N |
O |
||
| LEU | B:180 | B:180 | 0.0 | 0.0 | H | -75.3 | -33.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.659 |
N |
O |
|||||||||
| 2ab6 | 1 | P28161 | 100.0 | 7e-164 |
X-RAY |
2005-08-02 | LEU | A:180 | A:180 | 0.0 | 0.0 | H | -75.1 | -38.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.366 |
N |
O |
||
| LEU | B:180 | B:180 | 0.0 | 0.0 | H | -77.9 | -37.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.826 |
N |
O |
|||||||||
| LEU | C:180 | C:180 | 0.0 | 0.0 | H | -73.3 | -40.5 | NA | NA | NA | |||||||||||||
| LEU | D:180 | D:180 | 0.0 | 0.0 | H | -73.5 | -41.3 | NA | NA | NA | |||||||||||||
| 2gtu | 1 | P28161 | 100.0 | 7e-164 |
X-RAY |
1999-03-02 | LEU | A:180 | A:180 | 0.0 | 0.0 | H | -77.4 | -39.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.717 |
N |
O |
||
| LEU | B:180 | B:180 | 0.0 | 0.0 | H | -74.0 | -43.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.752 |
N |
O |
|||||||||
| 3gtu | 1 | P28161 | 100.0 | 7e-164 |
X-RAY |
1999-07-29 | LEU | A:180 | A:180 | 0.0 | 0.0 | H | -72.2 | -37.8 | 0.0 | 0.0 | 0.0 |
HOH |
9.397 |
CD1 |
O |
||
| LEU | C:180 | C:180 | 0.0 | 0.0 | H | -73.8 | -33.4 | NA | NA | NA | |||||||||||||
| 3gur | 1 | P28161 | 100.0 | 7e-164 |
X-RAY |
2009-10-27 | LEU | A:180 | A:180 | 0.0 | 0.0 | H | -71.2 | -46.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.615 |
N |
O |
||
| LEU | B:180 | B:180 | 0.0 | 0.0 | H | -62.0 | -48.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.915 |
N |
O |
|||||||||
| LEU | C:180 | C:180 | 0.0 | 0.0 | H | -73.6 | -41.7 | NA | NA | NA | |||||||||||||
| LEU | D:180 | D:180 | 0.0 | 0.0 | H | -67.2 | -38.5 | NA | NA | NA | |||||||||||||
| 5hwl | 1 | P28161 | 100.0 | 7e-164 |
X-RAY |
2017-11-08 | LEU | A:180 | A:180 | 0.0 | 0.0 | H | -67.5 | -42.8 | 0.0 | 0.0 | 0.0 |
HOH |
4.842 |
N |
O |
||
| LEU | B:180 | B:180 | 0.0 | 0.0 | H | -77.0 | -34.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.952 |
N |
O |
|||||||||
| 1hna | 1 | P28161 | 99.54 | 1e-162 |
X-RAY |
1994-01-31 | LEU | A:180 | A:180 | 0.0 | 0.0 | H | -72.8 | -40.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.851 |
N |
O |
||
| 1hnb | 1 | P28161 | 99.54 | 1e-162 |
X-RAY |
1994-01-31 | LEU | A:180 | A:180 | 0.0 | 0.0 | H | -66.7 | -48.2 | 0.0 | 0.0 | 0.0 | ||||||
| LEU | B:180 | B:180 | 0.0 | 0.0 | H | -63.1 | -37.6 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 1hnc | 1 | P28161 | 99.54 | 1e-162 |
X-RAY |
1994-01-31 | LEU | A:180 | A:180 | 0.0 | 0.0 | H | -67.2 | -51.0 | 0.0 | 0.0 | 0.0 | ||||||
| LEU | B:180 | B:180 | 0.0 | 0.0 | H | -78.9 | -43.0 | 0.0 | 0.0 | 0.0 | |||||||||||||
| LEU | C:180 | C:180 | 0.0 | 0.0 | H | -68.1 | -44.4 | NA | NA | NA | |||||||||||||
| LEU | D:180 | D:180 | 0.0 | 0.0 | H | -70.8 | -38.2 | NA | NA | NA | |||||||||||||
| 1xw6 | 1 | P09488 | 84.4 | 8e-141 |
X-RAY |
2004-12-21 | LEU | A:181 | A:180 | 0.0 | 0.0 | H | -75.1 | -36.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.033 |
N |
O |
||
| LEU | B:181 | B:180 | 0.0 | 0.0 | H | -75.9 | -35.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.806 |
N |
O |
|||||||||
| LEU | C:181 | C:180 | 0.0 | 0.0 | H | -76.2 | -36.1 | NA | NA | NA | |||||||||||||
| LEU | D:181 | D:180 | 0.0 | 0.0 | H | -76.2 | -33.8 | NA | NA | NA | |||||||||||||
| 1xwk | 1 | P09488 | 84.4 | 8e-141 |
X-RAY |
2004-12-21 | LEU | A:181 | A:180 | 0.0 | 0.0 | H | -70.5 | -43.0 | 0.0 | 0.0 | 0.0 |
HOH |
8.379 |
O |
O |
||
| LEU | B:181 | B:180 | 0.0 | 0.0 | H | -74.5 | -45.4 | NA | NA | NA | |||||||||||||
| LEU | C:181 | C:180 | 0.0 | 0.0 | H | -78.3 | -37.3 | 0.0 | 0.0 | 0.0 |
HOH |
5.389 |
N |
O |
|||||||||
| 1yj6 | 1 | P09488 | 84.4 | 8e-141 |
X-RAY |
2005-02-01 | LEU | A:181 | A:180 | 0.0 | 0.0 | H | -72.2 | -38.4 | 0.0 | 0.0 | 0.0 |
HOH |
5.681 |
N |
O |
||
| LEU | B:181 | B:180 | 0.0 | 0.0 | H | -77.2 | -31.5 | 0.0 | 0.0 | 0.0 |
HOH |
5.957 |
N |
O |
|||||||||
| LEU | C:181 | C:180 | 0.0 | 0.0 | H | -72.9 | -36.0 | NA | NA | NA | |||||||||||||
| 2f3m | 1 | P09488 | 84.4 | 8e-141 |
X-RAY |
2006-04-25 | LEU | A:181 | A:180 | 0.0 | 0.0 | H | -75.0 | -39.2 | 0.0 | 0.0 | 0.0 |
HOH |
9.053 |
CD1 |
O |
||
| LEU | B:181 | B:180 | 0.0 | 0.0 | H | -75.4 | -40.2 | 0.0 | 0.0 | 0.0 | |||||||||||||
| LEU | C:181 | C:180 | 0.0 | 0.0 | H | -73.9 | -40.0 | NA | NA | NA | |||||||||||||
| LEU | D:181 | D:180 | 0.0 | 0.0 | H | -74.7 | -39.4 | NA | NA | NA | |||||||||||||
| LEU | E:181 | E:180 | 0.0 | 0.0 | H | -77.0 | -37.5 | NA | NA | NA | |||||||||||||
| LEU | F:181 | F:180 | 0.0 | 0.0 | H | -60.9 | -52.0 | NA | NA | NA | |||||||||||||
| 7beu | 1 | P09488 | 84.4 | 8e-141 |
X-RAY |
2022-01-12 | LEU | A:181 | A:180 | 0.0 | 0.0 | H | -74.6 | -37.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.947 |
N |
O |
||
| LEU | B:181 | B:180 | 0.0 | 0.0 | H | -73.9 | -36.9 | NA | NA | NA | |||||||||||||
| LEU | C:181 | C:180 | 0.0 | 0.0 | H | -74.7 | -38.0 | NA | NA | NA | |||||||||||||
| LEU | D:181 | D:180 | 0.0 | 0.0 | H | -75.8 | -39.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.737 |
N |
O |
|||||||||
| 2dc5 | 1 | 30354091 | 83.41 | 1e-140 |
X-RAY |
2006-06-28 | LEU | A:188 | A:188 | 0.0 | 0.0 | H | -74.2 | -34.7 | 0.0 | 0.0 | 0.0 |
HOH |
4.769 |
N |
O |
||
| LEU | B:188 | B:188 | 0.0 | 0.0 | H | -78.0 | -33.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.902 |
N |
O |
|||||||||
| 1gtu | 1 | P09488 | 84.33 | 6e-140 |
X-RAY |
1999-02-02 | LEU | A:180 | A:180 | 0.0 | 0.0 | H | -69.6 | -45.2 | 0.0 | 0.0 | 0.0 | ||||||
| LEU | B:180 | B:180 | 0.0 | 0.0 | H | -74.8 | -38.1 | 0.0 | 0.0 | 0.0 | |||||||||||||
| LEU | C:180 | C:180 | 0.0 | 0.0 | H | -72.2 | -40.1 | NA | NA | NA | |||||||||||||
| LEU | D:180 | D:180 | 0.0 | 0.0 | H | -75.1 | -37.3 | NA | NA | NA | |||||||||||||
| 4gtu | 1 | Q03013 | 83.33 | 7e-139 |
X-RAY |
2000-01-14 | LEU | A:180 | A:180 | 0.0 | 0.0 | H | -70.6 | -41.5 | 0.0 | 0.0 | 0.0 | ||||||
| LEU | B:180 | B:180 | 0.0 | 0.0 | H | -72.1 | -24.4 | 0.0 | 0.0 | 0.0 | |||||||||||||
| LEU | C:180 | C:180 | 0.0 | 0.0 | H | -60.6 | -46.8 | NA | NA | NA | |||||||||||||
| LEU | D:180 | D:180 | 0.0 | 0.0 | H | -79.1 | -37.2 | NA | NA | NA | |||||||||||||
| LEU | E:180 | E:180 | 0.0 | 0.0 | H | -70.1 | -40.4 | NA | NA | NA | |||||||||||||
| LEU | F:180 | F:180 | 0.0 | 0.0 | H | -69.9 | -41.1 | NA | NA | NA | |||||||||||||
| LEU | G:180 | G:180 | 0.0 | 0.0 | H | -71.4 | -36.7 | NA | NA | NA | |||||||||||||
| LEU | H:180 | H:180 | 0.0 | 0.0 | H | -72.3 | -27.2 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p28161-f1 | 1 | P28161 | 100.0 | 3e-165 | LEU | A:181 | A:181 | 0.0 | 0.0 | H | -75.0 | -39.7 | |
| af-p09488-f1 | 1 | P09488 | 84.4 | 3e-141 | LEU | A:181 | A:181 | 0.0 | 0.0 | H | -74.6 | -37.4 | |
| af-q03013-f1 | 1 | Q03013 | 83.03 | 6e-140 | LEU | A:181 | A:181 | 0.0 | 0.0 | H | -74.0 | -38.4 | |
| af-p46439-f1 | 1 | P46439 | 81.19 | 6e-134 | LEU | A:181 | A:181 | 0.0 | 0.0 | H | -73.7 | -38.1 | |