Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 113212184 . A C CCDS30805.1:NM_006135.2:c.677aAg>aCg_NP_006126.1:p.226K>T Homo sapiens capping actin protein of muscle Z-line alpha subunit 1 (CAPZA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5nw4 13 A0PFK5 97.9 0.0 EM
 2017-08-02 LYS U:226 Y:226 136.0 0.68 H -90.9 -9.0 136.0 0.68 0.0
6f1t 4 A0PFK5 97.9 0.0 EM
 2018-01-17 LYS K:226 K:226 132.0 0.66 H -68.6 -21.6 132.0 0.66 0.0
6f1u 2 A0PFK5 97.9 0.0 EM
 2018-01-17 LYS D:226 K:226 132.0 0.66 H -68.6 -21.6 132.0 0.66 0.0
6f38 4 A0PFK5 97.9 0.0 EM
 2018-01-17 LYS K:226 K:226 65.0 NA H -62.7 -28.5 65.0 NA NA
6f3a 4 A0PFK5 97.9 0.0 EM
 2018-01-17 LYS K:226 K:226 54.0 NA H -64.3 -24.5 54.0 NA NA
6znl 4 A0PFK5 97.9 0.0 EM
 2020-07-29 LYS K:226 K:226 105.0 0.525 H -57.6 -42.5 105.0 0.525 0.0
5adx 4 A0PFK5 98.18 0.0 EM
 2015-12-30 LYS K:220 K:226 132.0 0.66 H -90.9 -9.0 132.0 0.66 0.0
5afu 8 A0PFK5 98.18 0.0 EM
 2015-03-11 LYS Q:220 K:226 132.0 0.66 H -90.9 -9.0 132.0 0.66 0.0
7ccc 3 Q5RKN9 96.5 0.0 X-RAY
 2021-02-03 LYS C:226 C:226 110.0 0.55 H -60.4 -50.7 110.0 0.55 0.0
7pdz 2 P47753 96.5 0.0 EM
 2021-09-01 LYS B:226 F:226 116.0 0.58 H -59.6 -46.0 116.0 0.58 0.0
1izn 1 P13127 92.31 0.0 X-RAY
 2003-04-08 LYS A:226 A:226 147.0 0.735 H -63.7 -22.5 147.0 0.735 0.0 HOH
 8.452
 N
 O
LYS C:226 C:226 167.0 0.835 H -47.8 -32.4 NA NA NA
2kz7 1 P13127 92.31 0.0 NMR
 2010-07-14 LYS A:226 A:226 149.0 0.745 H -63.7 -22.6 149.0 0.745 0.0
3aa0 1 P13127 92.31 0.0 X-RAY
 2010-08-04 LYS A:226 A:226 123.0 0.615 H -63.1 -42.9 123.0 0.615 0.0 HOH
 2.905
 O
 O
3aa1 1 P13127 92.31 0.0 X-RAY
 2010-08-04 LYS A:226 A:226 129.0 0.645 H -63.0 -40.4 129.0 0.645 0.0 HOH
 2.591
 O
 O
3aa6 1 P13127 92.31 0.0 X-RAY
 2010-08-04 LYS A:226 A:226 127.0 0.635 H -55.1 -49.5 127.0 0.635 0.0 HOH
 2.668
 O
 O
3aa7 1 P13127 92.31 0.0 X-RAY
 2010-08-04 LYS A:226 A:226 143.0 0.715 H -58.1 -47.0 143.0 0.715 0.0 HOH
 2.438
 NZ
 O
3aaa 1 P13127 92.31 0.0 X-RAY
 2010-08-04 LYS A:226 A:226 113.0 0.565 H -60.3 -42.9 113.0 0.565 0.0 HOH
 2.720
 O
 O
3aae 1 P13127 92.31 0.0 X-RAY
 2010-11-17 LYS A:226 A:226 157.0 0.785 H -66.4 -36.2 157.0 0.785 0.0
LYS C:226 C:226 159.0 0.795 H -65.2 -38.5 NA NA NA
LYS E:226 E:226 156.0 0.78 H -64.1 -37.1 NA NA NA
LYS G:226 G:226 157.0 0.785 H -66.5 -36.4 NA NA NA
LYS I:226 I:226 160.0 0.8 H -67.0 -37.2 NA NA NA
3lk2 1 P13127 92.31 0.0 X-RAY
 2010-04-07 LYS A:226 A:226 109.0 0.545 H -59.7 -34.1 109.0 0.545 0.0 HOH
 2.787
 O
 O
3lk3 1 P13127 92.31 0.0 X-RAY
 2010-04-07 LYS A:226 A:226 97.0 0.485 H -64.1 -38.4 97.0 0.485 0.0 HOH
 2.834
 O
 O
3lk4 1 P13127 92.31 0.0 X-RAY
 2010-04-07 LYS A:226 A:226 117.0 0.585 H -60.2 -43.9 117.0 0.585 0.0 HOH
 2.920
 O
 O
LYS D:226 D:226 119.0 0.595 H -61.4 -43.5 NA NA NA
LYS G:226 G:226 116.0 0.58 H -57.9 -44.2 NA NA NA
LYS J:226 J:226 117.0 0.585 H -60.8 -43.7 NA NA NA
LYS M:226 M:226 117.0 0.585 H -58.2 -43.3 NA NA NA
LYS P:226 P:226 117.0 0.585 H -59.8 -43.8 NA NA NA
LYS S:226 S:226 117.0 0.585 H -60.6 -43.5 NA NA NA
LYS V:226 V:226 116.0 0.58 H -58.2 -44.4 NA NA NA
LYS Y:226 Y:226 116.0 0.58 H -60.2 -43.9 NA NA NA
LYS BA:226 1:226 117.0 0.585 H -60.9 -43.0 NA NA NA
LYS EA:226 4:226 117.0 0.585 H -60.6 -44.1 NA NA NA
LYS HA:226 7:226 118.0 0.59 H -58.8 -43.2 NA NA NA
7ds2 1 P13127 92.31 0.0 X-RAY
 2021-03-03 LYS A:226 A:226 110.0 0.55 H -56.7 -41.8 110.0 0.55 0.0 HOH
 2.720
 O
 O
7ds3 1 P13127 92.31 0.0 X-RAY
 2021-03-03 LYS A:226 A:226 109.0 0.545 H -70.2 -39.1 109.0 0.545 0.0 HOH
 8.264
 O
 O
7ds4 1 P13127 92.31 0.0 X-RAY
 2021-03-03 LYS A:226 A:226 54.0 NA H -71.2 -31.3 54.0 NA NA HOH
 2.854
 O
 O
7ds6 1 P13127 92.31 0.0 X-RAY
 2021-03-03 LYS A:226 A:226 137.0 0.685 H -61.9 -45.3 137.0 0.685 0.0 HOH
 2.786
 O
 O
7ds8 1 P13127 92.31 0.0 X-RAY
 2021-03-03 LYS A:226 A:226 61.0 NA H -61.8 -43.8 61.0 NA NA HOH
 2.694
 O
 O
7dsa 1 P13127 92.31 0.0 X-RAY
 2021-03-03 LYS A:226 A:226 78.0 NA H -68.0 -24.6 78.0 NA NA
7dsb 1 P13127 92.31 0.0 X-RAY
 2021-03-03 LYS A:226 A:226 115.0 0.575 H -64.2 -39.0 115.0 0.575 0.0 HOH
 3.769
 CA
 O
2kxp 1 P13127 92.36 0.0 NMR
 2010-06-09 LYS A:220 A:226 145.0 0.725 H -57.1 -30.5 145.0 0.725 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p52907-f1 1 P52907 100.0 0.0 LYS A:226 A:226 135.0 0.675 H -63.4 -41.7
af-p47755-f1 1 P47755 86.71 0.0 LYS A:226 A:226 116.0 0.58 H -62.9 -46.4