Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 115828905 . T A CCDS882.1:NM_002506.2:c.512aAa>aTa_NP_002497.2:p.171K>I Homo sapiens nerve growth factor (NGF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6xuo 1 F6SVV7 94.62 8e-146 X-RAY
 2020-01-29 LYS A:154 A:50 106.0 0.53 E -91.9 157.8 93.0 0.465 0.065 A:F6SVV7:0.065
 ZN
 9.312
 CD
 ZN
3ij2 1 P01139 82.19 2e-135 X-RAY
 2010-01-12 ARG A:153 A:50 124.0 0.551 99.8 146.4 113.0 0.502 0.049 D:P07174:0.04
C:P01139:0.022
ARG C:153 B:50 122.0 0.542 100.9 146.4 113.0 0.502 0.04 B:P07174:0.031
A:P01139:0.018
1sg1 1 P01138 100.0 1e-87 X-RAY
 2004-06-01 LYS A:50 A:50 90.0 0.45 E -90.4 152.6 89.0 0.445 0.005 B:P01138:0.005
 HOH
 5.170
 O
 O
LYS B:50 B:50 93.0 0.465 -85.8 146.0 42.0 0.21 0.255 A:P01138:0.065
C:P07174:0.21
 HOH
 3.164
 NZ
 O
1www 1 P01138 100.0 1e-87 X-RAY
 1999-09-15 LYS A:50 V:50 89.0 0.445 E -66.2 127.4 89.0 0.445 0.0 HOH
 3.265
 CE
 O
LYS B:50 W:50 113.0 0.565 E -87.7 125.9 113.0 0.565 0.0 HOH
 3.771
 NZ
 O
2ifg 2 P01138 100.0 1e-87 X-RAY
 2007-02-13 LYS C:50 E:50 105.0 0.525 E -66.3 127.4 102.0 0.51 0.015 D:P01138:0.015
LYS D:50 F:50 114.0 0.57 E -87.6 125.9 114.0 0.57 0.0
4edw 1 P01138 100.0 1e-87 X-RAY
 2014-04-02 LYS A:50 V:50 121.0 0.605 E -79.0 136.0 115.0 0.575 0.03 C:None:0.03
 HOH
 9.572
 O
 O
4edx 1 P01138 100.0 1e-87 X-RAY
 2014-04-02 LYS A:50 W:50 143.0 0.715 E -74.2 133.5 103.0 0.515 0.2 C:None:0.19
D:P01138:0.015
 HOH
 3.852
 NZ
 O
LYS D:50 V:50 141.0 0.705 E -70.8 130.5 98.0 0.49 0.215 F:None:0.19
A:P01138:0.03
 HOH
 6.514
 NZ
 O
4zbn 2 P01138 100.0 1e-87 X-RAY
 2015-06-10 LYS C:50 A:50 100.0 0.5 E -66.3 154.2 93.0 0.465 0.035 D:P01138:0.035
 DG
DUZ
DUZ
HOH
 8.553
7.668
7.474
4.326
 NZ
CD
CE
O
 O3'
OP1
C29
O
LYS D:50 B:50 52.0 NA E -75.8 147.2 48.0 NA NA C:P01138:NA
 DG
DUZ
DUZ
 9.447
7.969
7.870
 CB
CB
O
 O3'
OP1
C30
6yw8 1 P01138 100.0 4e-86 NMR
 2021-05-12 LYS A:50 A:50 116.0 0.58 E -74.0 114.2 116.0 0.58 0.0
LYS B:50 B:50 118.0 0.59 E -74.2 113.9 118.0 0.59 0.0
4efv 1 ? 97.37 4e-81 X-RAY
 2012-08-22 LYS A:50 A:50 114.0 0.57 E -85.1 146.4 104.0 0.52 0.05 B:None:0.05
 HOH
 4.565
 O
 O
LYS B:50 B:50 125.0 0.625 E -73.7 144.5 117.0 0.585 0.04 A:None:0.04
 HOH
 2.751
 NZ
 O
5jz7 1 P01138 100.0 4e-80 X-RAY
 2017-01-11 LYS A:44 A:50 106.0 0.53 E -78.5 125.0 99.0 0.495 0.035 C:None:0.015
B:P01138:0.02
LYS B:44 B:50 106.0 0.53 E -79.3 126.1 99.0 0.495 0.035 A:P01138:0.025
H:None:0.01
LYS E:44 E:50 106.0 0.53 E -84.4 124.4 NA NA NA
LYS F:44 F:50 106.0 0.53 E -78.6 126.1 NA NA NA
4eax 1 P01139 89.17 1e-77 X-RAY
 2012-09-12 ARG A:50 A:50 121.0 0.538 E -109.0 138.5 111.0 0.493 0.045 B:P01139:0.044
 S12
HOH
 6.416
5.864
 O
CG
 C12
O
ARG B:50 B:50 74.0 0.329 E -111.4 141.9 70.0 0.311 0.018 S12
HOH
 2.748
5.923
 O
NH2
 N
O
ARG C:50 C:50 120.0 0.533 E -112.0 139.7 NA NA NA
ARG D:50 D:50 75.0 0.333 E -121.1 138.5 NA NA NA
4xpj 1 P01139 89.17 1e-77 X-RAY
 2015-07-15 ARG A:50 A:50 118.0 0.524 E -100.1 142.1 113.0 0.502 0.022 B:P01139:0.022
 LPY
HOH
 5.910
3.078
 O
NH1
 C31
O
ARG B:50 B:50 104.0 0.462 E -110.2 116.4 102.0 0.453 0.009 A:P01139:0.009
 LPY
HOH
 2.622
5.068
 N
N
 O2
O
1sgf 2 P01139 89.83 8e-77 X-RAY
 1998-05-27 ARG B:50 B:50 107.0 0.476 E -94.9 152.4 83.0 0.369 0.107 E:P01139:0.031
D:P00757:0.076
ARG E:50 Y:50 117.0 0.52 B -83.9 143.9 89.0 0.396 0.124 B:P01139:0.031
A:P00757:0.093
5lsd 1 P01139 89.83 8e-77 NMR
 2017-07-05 ARG A:50 A:50 170.0 0.756 E -80.5 105.7 156.0 0.693 0.063 B:P01139:0.062
ARG B:50 B:50 169.0 0.751 E -80.3 105.7 155.0 0.689 0.062 A:P01139:0.062
6ffy 2 P01139 90.43 4e-75 X-RAY
 2018-08-01 ARG B:50 B:171 138.0 0.613 E -100.1 133.4 49.0 0.218 0.395 C:P01139:0.013
A:Q9EPR5:0.382
ARG C:50 C:171 131.0 0.582 E -120.0 140.6 125.0 0.556 0.026 B:P01139:0.027
1btg 1 P01139 91.74 4e-71 X-RAY
 1996-03-08 ARG A:42 A:50 163.0 0.724 E -79.0 148.2 163.0 0.724 0.0 HOH
 4.944
 O
 O
ARG B:42 B:50 137.0 0.609 E -101.0 145.5 137.0 0.609 0.0 HOH
 3.397
 NH2
 O
ARG C:42 C:50 132.0 0.587 E -121.1 130.3 132.0 0.587 0.0 HOH
 6.363
 NH2
 O
1bet 1 P01139 92.52 2e-70 X-RAY
 1994-05-31 ARG A:41 A:50 90.0 0.4 E -85.8 145.2 86.0 0.382 0.018 A:P01139:0.018
 HOH
 2.841
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01138-f1 1 P01138 100.0 0.0 LYS A:171 A:171 72.0 0.36 E -113.9 155.2