Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 116930076 . T A CCDS887.1:NM_000701.7:c.350aTc>aAc_NP_000692.2:p.117I>N Homo sapiens ATPase Na+/K+ transporting subunit alpha 1 (ATP1A1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4hqj 1 P05024 98.14 0.0 X-RAY
 2013-10-02 ILE A:115 A:110 73.0 0.417 H -61.7 -32.4 73.0 0.417 0.0
ILE D:115 C:110 73.0 0.417 H -62.2 -33.4 NA NA NA
4hyt 1 P05024 98.14 0.0 X-RAY
 2013-06-26 ILE A:115 A:110 59.0 0.337 H -69.8 -26.1 59.0 0.337 0.0 OBN
 8.913
 C
 O1
ILE D:115 C:110 61.0 0.349 H -69.7 -26.1 NA NA NA
4res 1 P05024 98.14 0.0 X-RAY
 2015-01-28 ILE A:115 A:110 52.0 0.297 H -70.1 -29.6 52.0 0.297 0.0 BUF
 9.525
 C
 C1
ILE D:115 C:110 51.0 0.291 H -69.6 -29.9 NA NA NA
4ret 1 P05024 98.14 0.0 X-RAY
 2015-01-28 ILE A:115 A:110 58.0 0.331 H -75.2 -26.6 58.0 0.331 0.0 DGX
 7.364
 O
 C6X
ILE D:115 C:110 58.0 0.331 H -74.9 -26.9 NA NA NA
7evx 1 P05024 98.14 0.0 X-RAY
 2021-07-07 ILE A:115 A:110 67.0 0.383 H -71.8 -39.8 67.0 0.383 0.0 JEO
 8.943
 C
 CAT
ILE D:115 C:110 62.0 0.354 H -70.9 -38.8 NA NA NA
3wgu 1 I7HD36 98.62 0.0 X-RAY
 2013-10-09 ILE A:110 A:110 77.0 0.44 H -72.0 -30.9 77.0 0.44 0.0
ILE D:110 C:110 72.0 0.411 H -56.3 -42.6 NA NA NA
3wgv 1 I7HD36 98.62 0.0 X-RAY
 2013-10-09 ILE A:110 A:110 82.0 0.469 H -66.6 -31.4 82.0 0.469 0.0
ILE D:110 C:110 73.0 0.417 H -52.6 -45.9 NA NA NA
7d91 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ILE A:110 A:110 59.0 0.337 H -75.1 -28.6 59.0 0.337 0.0
7d92 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ILE A:110 A:110 65.0 0.371 H -66.6 -32.0 65.0 0.371 0.0 H0C
 7.368
 O
 C37
7d93 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ILE A:110 A:110 57.0 0.326 H -62.3 -56.1 57.0 0.326 0.0 H0C
 8.552
 O
 C37
ILE C:110 C:110 60.0 0.343 H -61.6 -54.6 NA NA NA
7d94 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ILE A:110 A:110 57.0 0.326 H -67.5 -35.1 57.0 0.326 0.0 BUF
 9.800
 C
 C19
ILE D:110 C:110 59.0 0.337 H -70.0 -36.9 NA NA NA
7ddf 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ILE A:110 A:110 61.0 0.349 H -72.4 -44.1 61.0 0.349 0.0
ILE D:110 C:110 61.0 0.349 H -66.0 -45.5 NA NA NA
7ddh 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ILE A:110 A:110 56.0 0.32 H -68.1 -31.5 56.0 0.32 0.0 DGX
 8.412
 O
 C6X
ILE D:110 C:110 57.0 0.326 H -68.8 -31.3 NA NA NA
7ddi 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ILE A:110 A:110 62.0 0.354 H -66.8 -36.1 62.0 0.354 0.0 F9R
 8.137
 O
 C6X
ILE D:110 C:110 61.0 0.349 H -68.4 -30.2 NA NA NA
7ddj 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ILE A:110 A:110 61.0 0.349 H -63.1 -50.0 61.0 0.349 0.0 OBN
 9.104
 C
 O19
ILE D:110 C:110 59.0 0.337 H -62.6 -51.8 NA NA NA
7ddk 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ILE A:110 A:110 58.0 0.331 H -69.1 -24.2 58.0 0.331 0.0 E4R
 9.954
 C
 C1
ILE D:110 C:110 54.0 0.309 H -65.0 -23.3 NA NA NA
7ddl 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ILE A:110 A:110 59.0 0.337 H -69.8 -41.8 59.0 0.337 0.0
ILE D:110 C:110 58.0 0.331 H -67.1 -41.8 NA NA NA
4xe5 1 Q08DA1 97.46 0.0 X-RAY
 2016-03-09 ILE A:115 A:115 63.0 0.36 H -68.6 -27.9 63.0 0.36 0.0 OBN
 9.177
 C
 O19
3b8e 1 P05024 98.4 0.0 X-RAY
 2007-12-18 ILE A:92 A:110 101.0 0.577 S -64.4 64.0 101.0 0.577 0.0
ILE D:92 C:110 84.0 0.48 S -64.2 63.5 NA NA NA
3kdp 1 P05024 98.4 0.0 X-RAY
 2010-02-16 ILE A:92 A:110 67.0 0.383 H -39.9 -40.0 67.0 0.383 0.0
ILE D:92 C:110 38.0 0.217 H -35.3 -45.1 NA NA NA
3n23 1 P05024 98.59 0.0 X-RAY
 2011-01-19 ILE A:86 A:110 100.0 0.571 H -65.6 -51.1 100.0 0.571 0.0 OBN
 8.128
 C
 O19
ILE D:86 C:110 98.0 0.56 H -66.2 -50.4 NA NA NA
2zxe 1 Q4H132 87.84 0.0 X-RAY
 2009-05-19 ILE A:122 A:117 78.0 0.446 H -59.1 -31.7 78.0 0.446 0.0
3a3y 1 Q4H132 87.84 0.0 X-RAY
 2009-09-08 ILE A:122 A:117 107.0 0.611 H -67.8 -32.5 107.0 0.611 0.0
5avq 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.0 -31.8 78.0 0.446 0.0
5avr 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.1 -31.7 78.0 0.446 0.0
5avs 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.0 -31.7 78.0 0.446 0.0
5avt 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.2 -31.6 78.0 0.446 0.0
5avu 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.2 -31.7 78.0 0.446 0.0
5avv 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.0 -31.8 78.0 0.446 0.0
5avw 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.0 -31.8 78.0 0.446 0.0
5avx 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.0 -31.8 78.0 0.446 0.0
5avy 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.1 -31.6 78.0 0.446 0.0
5avz 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.0 -31.8 78.0 0.446 0.0
5aw0 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.1 -31.7 78.0 0.446 0.0
5aw1 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.1 -31.6 78.0 0.446 0.0
5aw2 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.0 -31.8 78.0 0.446 0.0
5aw3 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.1 -31.7 78.0 0.446 0.0
5aw4 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.1 -31.6 78.0 0.446 0.0
5aw5 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.1 -31.6 78.0 0.446 0.0
5aw6 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.1 -31.6 78.0 0.446 0.0
5aw7 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.1 -31.6 78.0 0.446 0.0
5aw8 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -59.0 -31.7 78.0 0.446 0.0
5aw9 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ILE A:122 A:117 78.0 0.446 H -58.2 -37.7 78.0 0.446 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05023-f1 1 P05023 100.0 0.0 ILE A:117 A:117 67.0 0.383 H -70.7 -48.9
af-p13637-f1 1 P13637 87.88 0.0 ILE A:107 A:107 76.0 0.434 H -70.2 -49.7
af-p50993-f1 1 P50993 86.71 0.0 ILE A:115 A:115 66.0 0.377 H -70.8 -46.8