Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 116931578 . T A CCDS887.1:NM_000701.7:c.691Ttc>Atc_NP_000692.2:p.231F>I Homo sapiens ATPase Na+/K+ transporting subunit alpha 1 (ATP1A1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4hqj 1 P05024 98.14 0.0 X-RAY
 2013-10-02 PHE A:229 A:224 76.0 0.362 -82.1 149.1 76.0 0.362 0.0
PHE D:229 C:224 77.0 0.367 -81.2 148.9 NA NA NA
4hyt 1 P05024 98.14 0.0 X-RAY
 2013-06-26 PHE A:229 A:224 91.0 0.433 -74.5 129.0 91.0 0.433 0.0
PHE D:229 C:224 91.0 0.433 -74.2 128.9 NA NA NA
4res 1 P05024 98.14 0.0 X-RAY
 2015-01-28 PHE A:229 A:224 91.0 0.433 -74.3 124.5 91.0 0.433 0.0
PHE D:229 C:224 93.0 0.443 -74.5 124.7 NA NA NA
4ret 1 P05024 98.14 0.0 X-RAY
 2015-01-28 PHE A:229 A:224 92.0 0.438 -78.2 128.9 92.0 0.438 0.0
PHE D:229 C:224 94.0 0.448 -77.8 128.9 NA NA NA
7evx 1 P05024 98.14 0.0 X-RAY
 2021-07-07 PHE A:229 A:224 88.0 0.419 -66.1 130.1 88.0 0.419 0.0
PHE D:229 C:224 86.0 0.41 -65.9 129.5 NA NA NA
3wgu 1 I7HD36 98.62 0.0 X-RAY
 2013-10-09 PHE A:224 A:224 91.0 0.433 -80.8 113.7 91.0 0.433 0.0
PHE D:224 C:224 98.0 0.467 -71.1 122.1 NA NA NA
3wgv 1 I7HD36 98.62 0.0 X-RAY
 2013-10-09 PHE A:224 A:224 95.0 0.452 -100.2 123.6 95.0 0.452 0.0
PHE D:224 C:224 97.0 0.462 -77.0 125.5 NA NA NA
7d91 1 P05024 98.13 0.0 X-RAY
 2021-01-27 PHE A:224 A:224 82.0 0.39 -64.0 130.9 82.0 0.39 0.0
7d92 1 P05024 98.13 0.0 X-RAY
 2021-01-27 PHE A:224 A:224 83.0 0.395 -63.5 129.8 83.0 0.395 0.0
7d93 1 P05024 98.13 0.0 X-RAY
 2021-01-27 PHE A:224 A:224 87.0 0.414 -68.7 129.8 87.0 0.414 0.0
PHE C:224 C:224 87.0 0.414 -70.6 127.7 NA NA NA
7d94 1 P05024 98.13 0.0 X-RAY
 2021-01-27 PHE A:224 A:224 87.0 0.414 -68.9 129.3 87.0 0.414 0.0
PHE D:224 C:224 86.0 0.41 -70.4 128.0 NA NA NA
7ddf 1 P05024 98.13 0.0 X-RAY
 2021-01-27 PHE A:224 A:224 83.0 0.395 -66.8 130.2 83.0 0.395 0.0
PHE D:224 C:224 88.0 0.419 -67.5 129.2 NA NA NA
7ddh 1 P05024 98.13 0.0 X-RAY
 2021-01-27 PHE A:224 A:224 87.0 0.414 -72.8 120.8 87.0 0.414 0.0
PHE D:224 C:224 84.0 0.4 -73.9 118.4 NA NA NA
7ddi 1 P05024 98.13 0.0 X-RAY
 2021-01-27 PHE A:224 A:224 84.0 0.4 -63.5 131.7 84.0 0.4 0.0
PHE D:224 C:224 85.0 0.405 -64.0 131.1 NA NA NA
7ddj 1 P05024 98.13 0.0 X-RAY
 2021-01-27 PHE A:224 A:224 87.0 0.414 -69.1 129.3 87.0 0.414 0.0
PHE D:224 C:224 85.0 0.405 -70.4 127.5 NA NA NA
7ddk 1 P05024 98.13 0.0 X-RAY
 2021-01-27 PHE A:224 A:224 82.0 0.39 -69.3 129.3 82.0 0.39 0.0
PHE D:224 C:224 85.0 0.405 -70.6 128.6 NA NA NA
7ddl 1 P05024 98.13 0.0 X-RAY
 2021-01-27 PHE A:224 A:224 88.0 0.419 -68.2 129.7 88.0 0.419 0.0
PHE D:224 C:224 85.0 0.405 -70.2 128.4 NA NA NA
4xe5 1 Q08DA1 97.46 0.0 X-RAY
 2016-03-09 PHE A:229 A:229 89.0 0.424 -79.5 121.2 89.0 0.424 0.0
3b8e 1 P05024 98.4 0.0 X-RAY
 2007-12-18 PHE A:206 A:224 56.0 0.267 86.2 -179.3 56.0 0.267 0.0
PHE D:206 C:224 56.0 0.267 86.5 -178.5 NA NA NA
3kdp 1 P05024 98.4 0.0 X-RAY
 2010-02-16 PHE A:206 A:224 89.0 0.424 -55.3 131.1 89.0 0.424 0.0
PHE D:206 C:224 90.0 0.429 -54.1 132.3 NA NA NA
3n23 1 P05024 98.59 0.0 X-RAY
 2011-01-19 PHE A:200 A:224 81.0 0.386 -66.0 138.0 81.0 0.386 0.0
PHE D:200 C:224 79.0 0.376 -62.1 139.7 NA NA NA
2zxe 1 Q4H132 87.84 0.0 X-RAY
 2009-05-19 PHE A:236 A:231 68.0 0.324 -72.6 132.9 68.0 0.324 0.0 HOH
 4.944
 CZ
 O
3a3y 1 Q4H132 87.84 0.0 X-RAY
 2009-09-08 PHE A:236 A:231 70.0 0.333 -58.4 141.4 70.0 0.333 0.0 HOH
 5.495
 CZ
 O
5avq 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.6 132.9 68.0 0.324 0.0
5avr 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.6 132.9 68.0 0.324 0.0
5avs 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.6 132.9 68.0 0.324 0.0
5avt 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.5 132.8 68.0 0.324 0.0
5avu 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.6 132.8 68.0 0.324 0.0
5avv 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.7 132.8 68.0 0.324 0.0
5avw 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.6 132.8 68.0 0.324 0.0
5avx 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.5 132.9 68.0 0.324 0.0
5avy 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.6 132.8 68.0 0.324 0.0
5avz 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.5 132.8 68.0 0.324 0.0
5aw0 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.5 132.8 68.0 0.324 0.0
5aw1 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.6 132.9 68.0 0.324 0.0
5aw2 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.6 132.9 68.0 0.324 0.0
5aw3 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.7 132.9 68.0 0.324 0.0
5aw4 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.6 132.9 68.0 0.324 0.0
5aw5 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.5 132.8 68.0 0.324 0.0
5aw6 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.5 132.9 68.0 0.324 0.0
5aw7 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.5 132.8 68.0 0.324 0.0
5aw8 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 68.0 0.324 -72.6 132.8 68.0 0.324 0.0
5aw9 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:236 A:231 70.0 0.333 -66.9 136.7 70.0 0.333 0.0 HOH
 4.973
 CZ
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05023-f1 1 P05023 100.0 0.0 PHE A:231 A:231 84.0 0.4 -65.5 130.1
af-p13637-f1 1 P13637 87.88 0.0 CYS A:221 A:221 58.0 0.43 -72.1 119.8
af-p50993-f1 1 P50993 86.71 0.0 PHE A:229 A:229 83.0 0.395 -66.4 123.6