Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 116932301 . T A CCDS887.1:NM_000701.7:c.995gTg>gAg_NP_000692.2:p.332V>E Homo sapiens ATPase Na+/K+ transporting subunit alpha 1 (ATP1A1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4hqj 1 P05024 98.14 0.0 X-RAY
 2013-10-02 VAL A:330 A:325 5.0 0.032 S -101.0 113.8 5.0 0.032 0.0 NA
NA
 2.418
5.627
 O
N
 NA
NA
VAL D:330 C:325 5.0 0.032 S -100.7 114.0 NA NA NA
4hyt 1 P05024 98.14 0.0 X-RAY
 2013-06-26 VAL A:330 A:325 5.0 0.032 S -82.9 121.7 5.0 0.032 0.0 MG
OBN
HOH
 4.635
5.369
2.958
 O
O
O
 MG
O23
O
VAL D:330 C:325 5.0 0.032 S -82.9 122.2 NA NA NA
4res 1 P05024 98.14 0.0 X-RAY
 2015-01-28 VAL A:330 A:325 5.0 0.032 S -104.8 124.1 5.0 0.032 0.0 BUF
K
K
 4.828
5.833
2.851
 O
C
O
 O24
K
K
VAL D:330 C:325 5.0 0.032 S -103.5 123.0 NA NA NA
4ret 1 P05024 98.14 0.0 X-RAY
 2015-01-28 VAL A:330 A:325 6.0 0.039 S -87.3 124.6 6.0 0.039 0.0 MG
DGX
HOH
 4.625
4.697
3.076
 O
O
O
 MG
O23
O
VAL D:330 C:325 5.0 0.032 S -87.3 124.6 NA NA NA
7evx 1 P05024 98.14 0.0 X-RAY
 2021-07-07 VAL A:330 A:325 12.0 0.077 S -102.5 121.4 12.0 0.077 0.0 MG
JEO
HOH
 4.925
9.454
3.371
 O
N
O
 MG
OAA
O
VAL D:330 C:325 8.0 0.052 S -102.5 121.4 NA NA NA
3wgu 1 I7HD36 98.62 0.0 X-RAY
 2013-10-09 VAL A:325 A:325 5.0 0.032 S -121.5 123.8 5.0 0.032 0.0 NA
NA
HOH
 2.286
5.591
3.679
 O
N
O
 NA
NA
O
VAL D:325 C:325 3.0 0.019 S -108.2 125.9 NA NA NA
3wgv 1 I7HD36 98.62 0.0 X-RAY
 2013-10-09 VAL A:325 A:325 4.0 0.026 S -122.9 124.6 4.0 0.026 0.0 NA
NA
EFO
HOH
 2.323
5.656
7.330
3.917
 O
N
CG1
O
 NA
NA
C3A
O
VAL D:325 C:325 2.0 0.013 S -111.5 124.6 NA NA NA
7d91 1 P05024 98.13 0.0 X-RAY
 2021-01-27 VAL A:325 A:325 5.0 0.032 S -104.0 118.6 5.0 0.032 0.0 MG
HOH
 4.345
4.019
 O
O
 MG
O
7d92 1 P05024 98.13 0.0 X-RAY
 2021-01-27 VAL A:325 A:325 11.0 0.071 S -107.4 123.8 11.0 0.071 0.0 MG
H0C
HOH
 4.292
6.120
3.697
 O
O
O
 MG
O9
O
7d93 1 P05024 98.13 0.0 X-RAY
 2021-01-27 VAL A:325 A:325 8.0 0.052 S -114.4 118.7 8.0 0.052 0.0 MG
H0C
HOH
 4.516
6.667
3.545
 O
O
O
 MG
O9
O
VAL C:325 C:325 11.0 0.071 S -117.3 123.5 NA NA NA
7d94 1 P05024 98.13 0.0 X-RAY
 2021-01-27 VAL A:325 A:325 8.0 0.052 S -113.7 120.0 8.0 0.052 0.0 MG
RB
BUF
HOH
 3.051
5.715
5.609
3.913
 O
O
O
O
 MG
RB
O24
O
VAL D:325 C:325 8.0 0.052 S -114.0 118.5 NA NA NA
7ddf 1 P05024 98.13 0.0 X-RAY
 2021-01-27 VAL A:325 A:325 13.0 0.084 S -101.1 122.0 13.0 0.084 0.0 MG
HOH
 4.694
3.561
 O
O
 MG
O
VAL D:325 C:325 8.0 0.052 S -102.9 117.3 NA NA NA
7ddh 1 P05024 98.13 0.0 X-RAY
 2021-01-27 VAL A:325 A:325 8.0 0.052 S -104.4 116.0 8.0 0.052 0.0 MG
DGX
HOH
 4.566
5.604
3.521
 O
O
O
 MG
O23
O
VAL D:325 C:325 8.0 0.052 S -104.1 114.1 NA NA NA
7ddi 1 P05024 98.13 0.0 X-RAY
 2021-01-27 VAL A:325 A:325 8.0 0.052 S -105.5 115.4 8.0 0.052 0.0 MG
F9R
HOH
 4.428
5.574
3.307
 O
O
O
 MG
O23
O
VAL D:325 C:325 7.0 0.045 S -108.2 115.4 NA NA NA
7ddj 1 P05024 98.13 0.0 X-RAY
 2021-01-27 VAL A:325 A:325 9.0 0.058 S -114.5 113.1 9.0 0.058 0.0 MG
OBN
HOH
 4.488
6.278
3.551
 O
N
O
 MG
O23
O
VAL D:325 C:325 7.0 0.045 S -114.4 111.4 NA NA NA
7ddk 1 P05024 98.13 0.0 X-RAY
 2021-01-27 VAL A:325 A:325 10.0 0.065 S -108.7 115.1 10.0 0.065 0.0 MG
E4R
HOH
 4.568
7.141
3.594
 O
O
O
 MG
C24
O
VAL D:325 C:325 9.0 0.058 S -107.5 115.0 NA NA NA
7ddl 1 P05024 98.13 0.0 X-RAY
 2021-01-27 VAL A:325 A:325 7.0 0.045 S -112.9 105.2 7.0 0.045 0.0 MG
BUF
HOH
 4.661
5.507
3.669
 O
O
O
 MG
O24
O
VAL D:325 C:325 9.0 0.058 S -117.2 105.4 NA NA NA
4xe5 1 Q08DA1 97.46 0.0 X-RAY
 2016-03-09 VAL A:330 A:330 10.0 0.065 S -87.9 121.4 10.0 0.065 0.0 MG
OBN
HOH
 4.563
4.789
3.158
 O
O
O
 MG
O23
O
3b8e 1 P05024 98.4 0.0 X-RAY
 2007-12-18 VAL A:307 A:325 2.0 0.013 S -78.0 109.0 2.0 0.013 0.0 RB
RB
 6.438
3.572
 O
O
 RB
RB
VAL D:307 C:325 1.0 0.006 S -72.8 97.6 NA NA NA
3kdp 1 P05024 98.4 0.0 X-RAY
 2010-02-16 VAL A:307 A:325 1.0 0.006 S -56.8 116.5 1.0 0.006 0.0 RB
RB
 6.573
3.095
 O
O
 RB
RB
VAL D:307 C:325 0.0 0.0 S -90.3 106.2 NA NA NA
3n23 1 P05024 98.59 0.0 X-RAY
 2011-01-19 VAL A:301 A:325 24.0 0.155 S -120.7 112.9 24.0 0.155 0.0 OBN
 6.873
 N
 O23
VAL D:301 C:325 26.0 0.168 S -120.8 113.7 NA NA NA
2zxe 1 Q4H132 87.84 0.0 X-RAY
 2009-05-19 VAL A:337 A:332 1.0 0.006 S -77.1 122.5 1.0 0.006 0.0 K
K
HOH
 5.843
2.758
4.798
 O
O
N
 K
K
O
3a3y 1 Q4H132 87.84 0.0 X-RAY
 2009-09-08 VAL A:337 A:332 2.0 0.013 S -92.5 111.6 2.0 0.013 0.0 K
K
OBN
HOH
 6.296
3.502
5.923
5.131
 O
O
N
O
 K
K
O23
O
5avq 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -77.1 122.5 1.0 0.006 0.0 K
TL
K
TL
HOH
 5.843
5.843
2.758
2.758
7.404
 O
O
O
O
O
 K
TL
K
TL
O
5avr 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -77.1 122.5 1.0 0.006 0.0 K
TL
K
TL
HOH
 5.844
5.844
2.759
2.759
7.405
 O
O
O
O
O
 K
TL
K
TL
O
5avs 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -77.1 122.6 1.0 0.006 0.0 K
TL
TL
HOH
 5.843
5.843
2.758
7.404
 O
O
O
O
 K
TL
TL
O
5avt 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -77.0 122.5 1.0 0.006 0.0 K
TL
TL
HOH
 5.843
5.843
2.758
7.404
 O
O
O
O
 K
TL
TL
O
5avu 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -77.1 122.5 1.0 0.006 0.0 K
TL
TL
HOH
 5.843
5.843
2.758
7.405
 O
O
O
O
 K
TL
TL
O
5avv 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -77.1 122.6 1.0 0.006 0.0 TL
TL
HOH
 5.843
2.758
7.406
 O
O
O
 TL
TL
O
5avw 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -77.1 122.6 1.0 0.006 0.0 TL
TL
HOH
 5.843
2.759
7.405
 O
O
O
 TL
TL
O
5avx 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -77.1 122.5 1.0 0.006 0.0 TL
TL
HOH
 5.843
2.759
7.405
 O
O
O
 TL
TL
O
5avy 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -77.0 122.4 1.0 0.006 0.0 TL
TL
HOH
 5.843
2.758
7.405
 O
O
O
 TL
TL
O
5avz 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -77.1 122.5 1.0 0.006 0.0 TL
TL
HOH
 5.842
2.758
7.405
 O
O
O
 TL
TL
O
5aw0 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -77.1 122.5 1.0 0.006 0.0 TL
TL
HOH
 5.842
2.757
7.405
 O
O
O
 TL
TL
O
5aw1 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -77.1 122.5 1.0 0.006 0.0 K
TL
TL
HOH
 5.843
5.843
2.758
7.405
 O
O
O
O
 K
TL
TL
O
5aw2 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -77.1 122.6 1.0 0.006 0.0 TL
TL
HOH
 5.842
2.758
7.404
 O
O
O
 TL
TL
O
5aw3 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -77.1 122.6 1.0 0.006 0.0 TL
TL
HOH
 5.843
2.758
7.405
 O
O
O
 TL
TL
O
5aw4 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -77.0 122.5 1.0 0.006 0.0 K
RB
K
RB
HOH
 5.842
5.842
2.758
2.758
7.404
 O
O
O
O
O
 K
RB
K
RB
O
5aw5 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -77.1 122.5 1.0 0.006 0.0 K
RB
K
RB
HOH
 5.842
5.842
2.758
2.758
7.405
 O
O
O
O
O
 K
RB
K
RB
O
5aw6 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -77.1 122.6 1.0 0.006 0.0 K
RB
K
RB
HOH
 5.842
5.842
2.758
2.758
7.404
 O
O
O
O
O
 K
RB
K
RB
O
5aw7 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -76.9 122.5 1.0 0.006 0.0 K
RB
RB
HOH
 5.843
5.843
2.758
7.405
 O
O
O
O
 K
RB
RB
O
5aw8 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -77.0 122.6 1.0 0.006 0.0 RB
RB
HOH
 5.841
2.756
7.403
 O
O
O
 RB
RB
O
5aw9 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 VAL A:337 A:332 1.0 0.006 S -74.1 119.7 1.0 0.006 0.0 K
K
HOH
 5.859
2.927
4.849
 O
O
N
 K
K
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05023-f1 1 P05023 100.0 0.0 VAL A:332 A:332 3.0 0.019 S -92.3 116.6
af-p13637-f1 1 P13637 87.88 0.0 VAL A:322 A:322 1.0 0.006 S -93.9 113.0
af-p50993-f1 1 P50993 86.71 0.0 VAL A:330 A:330 1.0 0.006 S -94.0 112.4