Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 116932304 | . | C | A | CCDS887.1:NM_000701.7:c.998cCg>cAg_NP_000692.2:p.333P>Q | Homo sapiens ATPase Na+/K+ transporting subunit alpha 1 (ATP1A1), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4hqj | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2013-10-02 | PRO | A:331 | A:326 | 7.0 | 0.048 | -70.8 | 108.6 | 7.0 | 0.048 | 0.0 |
NA NA |
3.882 6.670 |
N N |
NA NA |
|||
| PRO | D:331 | C:326 | 8.0 | 0.055 | -70.8 | 107.7 | NA | NA | NA | ||||||||||||||
| 4hyt | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2013-06-26 | PRO | A:331 | A:326 | 1.0 | 0.007 | -77.5 | 100.0 | 1.0 | 0.007 | 0.0 |
MG OBN HOH |
5.041 7.621 3.123 |
CA N CA |
MG O23 O |
|||
| PRO | D:331 | C:326 | 1.0 | 0.007 | -77.5 | 100.0 | NA | NA | NA | ||||||||||||||
| 4res | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2015-01-28 | PRO | A:331 | A:326 | 0.0 | 0.0 | -84.8 | 86.7 | 0.0 | 0.0 | 0.0 |
BUF K K |
6.918 4.026 4.421 |
N CB N |
O24 K K |
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| PRO | D:331 | C:326 | 0.0 | 0.0 | -83.8 | 86.6 | NA | NA | NA | ||||||||||||||
| 4ret | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2015-01-28 | PRO | A:331 | A:326 | 0.0 | 0.0 | -79.7 | 84.0 | 0.0 | 0.0 | 0.0 |
MG DGX HOH |
4.986 6.945 3.423 |
CA N CA |
MG O23 O |
|||
| PRO | D:331 | C:326 | 0.0 | 0.0 | -79.6 | 84.0 | NA | NA | NA | ||||||||||||||
| 7evx | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2021-07-07 | PRO | A:331 | A:326 | 0.0 | 0.0 | -69.4 | 103.3 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.785 3.734 |
CA CA |
MG O |
|||
| PRO | D:331 | C:326 | 0.0 | 0.0 | -70.2 | 102.5 | NA | NA | NA | ||||||||||||||
| 3wgu | 1 | I7HD36 | 98.62 | 0.0 |
X-RAY |
2013-10-09 | PRO | A:326 | A:326 | 4.0 | 0.028 | -84.9 | 77.5 | 4.0 | 0.028 | 0.0 |
NA NA NA PC1 HOH |
3.869 6.502 9.546 9.441 4.052 |
N N CB CG CA |
NA NA NA C32 O |
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| PRO | D:326 | C:326 | 5.0 | 0.034 | -75.0 | 82.2 | NA | NA | NA | ||||||||||||||
| 3wgv | 1 | I7HD36 | 98.62 | 0.0 |
X-RAY |
2013-10-09 | PRO | A:326 | A:326 | 5.0 | 0.034 | -85.2 | 75.9 | 5.0 | 0.034 | 0.0 |
NA NA NA PC1 EFO HOH |
4.097 6.636 9.782 9.397 7.359 4.366 |
N N CB CG O CA |
NA NA NA C32 O36 O |
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| PRO | D:326 | C:326 | 5.0 | 0.034 | -77.3 | 72.3 | NA | NA | NA | ||||||||||||||
| 7d91 | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:326 | A:326 | 0.0 | 0.0 | -69.8 | 105.2 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.761 5.697 |
CA N |
MG O |
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| 7d92 | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:326 | A:326 | 1.0 | 0.007 | -74.2 | 105.8 | 1.0 | 0.007 | 0.0 |
MG H0C HOH |
4.735 8.296 4.411 |
CA N CA |
MG O9 O |
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| 7d93 | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:326 | A:326 | 0.0 | 0.0 | -66.4 | 104.1 | 0.0 | 0.0 | 0.0 |
MG H0C HOH |
4.901 8.806 4.065 |
CA N CA |
MG O9 O |
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| PRO | C:326 | C:326 | 2.0 | 0.014 | -76.0 | 102.5 | NA | NA | NA | ||||||||||||||
| 7d94 | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:326 | A:326 | 1.0 | 0.007 | -67.7 | 102.4 | 1.0 | 0.007 | 0.0 |
MG RB BUF HOH |
4.579 5.233 7.823 5.692 |
CA CA C C |
MG RB O24 O |
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| PRO | D:326 | C:326 | 1.0 | 0.007 | -66.7 | 102.9 | NA | NA | NA | ||||||||||||||
| 7ddf | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:326 | A:326 | 0.0 | 0.0 | -68.4 | 105.6 | 0.0 | 0.0 | 0.0 |
MG HOH |
5.009 4.148 |
CA CA |
MG O |
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| PRO | D:326 | C:326 | 3.0 | 0.021 | -71.2 | 106.2 | NA | NA | NA | ||||||||||||||
| 7ddh | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:326 | A:326 | 0.0 | 0.0 | -67.8 | 106.4 | 0.0 | 0.0 | 0.0 |
MG DGX HOH |
4.889 7.793 4.006 |
CA N CA |
MG O23 O |
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| PRO | D:326 | C:326 | 1.0 | 0.007 | -68.2 | 106.3 | NA | NA | NA | ||||||||||||||
| 7ddi | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:326 | A:326 | 0.0 | 0.0 | -68.7 | 103.8 | 0.0 | 0.0 | 0.0 |
MG F9R HOH |
4.770 7.750 3.838 |
CA N CA |
MG O23 O |
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| PRO | D:326 | C:326 | 1.0 | 0.007 | -69.3 | 105.1 | NA | NA | NA | ||||||||||||||
| 7ddj | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:326 | A:326 | 1.0 | 0.007 | -65.9 | 102.0 | 1.0 | 0.007 | 0.0 |
MG OBN HOH |
4.891 8.427 4.134 |
CA N CA |
MG O23 O |
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| PRO | D:326 | C:326 | 3.0 | 0.021 | -66.4 | 102.7 | NA | NA | NA | ||||||||||||||
| 7ddk | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:326 | A:326 | 1.0 | 0.007 | -67.2 | 103.9 | 1.0 | 0.007 | 0.0 |
MG E4R HOH |
4.712 9.210 3.942 |
CA N CA |
MG C24 O |
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| PRO | D:326 | C:326 | 1.0 | 0.007 | -68.3 | 102.0 | NA | NA | NA | ||||||||||||||
| 7ddl | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | PRO | A:326 | A:326 | 1.0 | 0.007 | -56.3 | 107.5 | 1.0 | 0.007 | 0.0 |
MG BUF HOH |
4.739 7.520 3.933 |
CA N CA |
MG O24 O |
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| PRO | D:326 | C:326 | 3.0 | 0.021 | -57.4 | 108.2 | NA | NA | NA | ||||||||||||||
| 4xe5 | 1 | Q08DA1 | 97.46 | 0.0 |
X-RAY |
2016-03-09 | PRO | A:331 | A:331 | 0.0 | 0.0 | -76.1 | 82.9 | 0.0 | 0.0 | 0.0 |
MG OBN HOH |
4.519 7.041 3.212 |
CA N CA |
MG O23 O |
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| 3b8e | 1 | P05024 | 98.4 | 0.0 |
X-RAY |
2007-12-18 | PRO | A:308 | A:326 | 2.0 | 0.014 | -61.0 | 76.9 | 2.0 | 0.014 | 0.0 |
RB RB |
4.949 4.188 |
CB CA |
RB RB |
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| PRO | D:308 | C:326 | 0.0 | 0.0 | -67.4 | 72.8 | NA | NA | NA | ||||||||||||||
| 3kdp | 1 | P05024 | 98.4 | 0.0 |
X-RAY |
2010-02-16 | PRO | A:308 | A:326 | 0.0 | 0.0 | -67.0 | -1.5 | 0.0 | 0.0 | 0.0 |
RB RB |
5.070 4.047 |
O CA |
RB RB |
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| PRO | D:308 | C:326 | 0.0 | 0.0 | -65.8 | 79.7 | NA | NA | NA | ||||||||||||||
| 3n23 | 1 | P05024 | 98.59 | 0.0 |
X-RAY |
2011-01-19 | PRO | A:302 | A:326 | 8.0 | 0.055 | -54.5 | 123.3 | 8.0 | 0.055 | 0.0 |
OBN |
9.185 |
N |
O23 |
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| PRO | D:302 | C:326 | 10.0 | 0.069 | -54.7 | 122.1 | NA | NA | NA | ||||||||||||||
| 2zxe | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2009-05-19 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.4 | 88.3 | 1.0 | 0.007 | 0.0 |
K K HOH |
4.845 4.076 2.550 |
CB CA O |
K K O |
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| 3a3y | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2009-09-08 | PRO | A:338 | A:333 | 0.0 | 0.0 | -73.0 | 102.4 | 0.0 | 0.0 | 0.0 |
K K OBN HOH |
5.127 4.445 8.824 3.146 |
CB CA N CA |
K K O23 O |
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| 5avq | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.4 | 88.4 | 1.0 | 0.007 | 0.0 |
K TL K TL HOH |
4.845 4.845 4.076 4.076 5.978 |
CB CB CA CA CB |
K TL K TL O |
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| 5avr | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.4 | 88.4 | 1.0 | 0.007 | 0.0 |
K TL K TL HOH |
4.845 4.845 4.076 4.076 5.980 |
CB CB CA CA CB |
K TL K TL O |
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| 5avs | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.4 | 88.2 | 1.0 | 0.007 | 0.0 |
K TL TL HOH |
4.845 4.845 4.076 5.979 |
CB CB CA CB |
K TL TL O |
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| 5avt | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.3 | 88.3 | 1.0 | 0.007 | 0.0 |
K TL TL HOH |
4.846 4.846 4.077 5.979 |
CB CB CA CB |
K TL TL O |
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| 5avu | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.3 | 88.3 | 1.0 | 0.007 | 0.0 |
K TL TL HOH |
4.846 4.846 4.076 5.979 |
CB CB CA CB |
K TL TL O |
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| 5avv | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.5 | 88.3 | 1.0 | 0.007 | 0.0 |
TL TL HOH |
4.845 4.076 5.979 |
CB CA CB |
TL TL O |
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| 5avw | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.4 | 88.3 | 1.0 | 0.007 | 0.0 |
TL TL HOH |
4.846 4.077 5.979 |
CB CA CB |
TL TL O |
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| 5avx | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.4 | 88.4 | 1.0 | 0.007 | 0.0 |
TL TL HOH |
4.846 4.077 5.979 |
CB CA CB |
TL TL O |
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| 5avy | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.4 | 88.3 | 1.0 | 0.007 | 0.0 |
TL TL HOH |
4.845 4.076 5.979 |
CB CA CB |
TL TL O |
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| 5avz | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.3 | 88.3 | 1.0 | 0.007 | 0.0 |
TL TL HOH |
4.846 4.077 5.980 |
CB CA CB |
TL TL O |
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| 5aw0 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.3 | 88.3 | 1.0 | 0.007 | 0.0 |
TL TL HOH |
4.845 4.076 5.979 |
CB CA CB |
TL TL O |
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| 5aw1 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.4 | 88.3 | 1.0 | 0.007 | 0.0 |
K TL TL HOH |
4.845 4.845 4.076 5.979 |
CB CB CA CB |
K TL TL O |
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| 5aw2 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.4 | 88.3 | 1.0 | 0.007 | 0.0 |
TL TL HOH |
4.845 4.076 5.979 |
CB CA CB |
TL TL O |
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| 5aw3 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.4 | 88.4 | 1.0 | 0.007 | 0.0 |
TL TL HOH |
4.845 4.075 5.979 |
CB CA CB |
TL TL O |
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| 5aw4 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.4 | 88.4 | 1.0 | 0.007 | 0.0 |
K RB K RB HOH |
4.844 4.844 4.076 4.076 5.977 |
CB CB CA CA CB |
K RB K RB O |
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| 5aw5 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.3 | 88.3 | 1.0 | 0.007 | 0.0 |
K RB K RB HOH |
4.844 4.844 4.077 4.077 5.978 |
CB CB CA CA CB |
K RB K RB O |
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| 5aw6 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.4 | 88.3 | 1.0 | 0.007 | 0.0 |
K RB K RB HOH |
4.845 4.845 4.078 4.078 5.978 |
CB CB CA CA CB |
K RB K RB O |
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| 5aw7 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.4 | 88.4 | 1.0 | 0.007 | 0.0 |
K RB RB HOH |
4.846 4.846 4.076 5.979 |
CB CB CA CB |
K RB RB O |
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| 5aw8 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -80.4 | 88.3 | 1.0 | 0.007 | 0.0 |
RB RB HOH |
4.844 4.077 5.978 |
CB CA CB |
RB RB O |
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| 5aw9 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | PRO | A:338 | A:333 | 1.0 | 0.007 | -78.5 | 86.3 | 1.0 | 0.007 | 0.0 |
K K HOH |
4.784 4.129 2.802 |
CB CA O |
K K O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05023-f1 | 1 | P05023 | 100.0 | 0.0 | PRO | A:333 | A:333 | 2.0 | 0.014 | -78.2 | 91.5 | ||
| af-p13637-f1 | 1 | P13637 | 87.88 | 0.0 | PRO | A:323 | A:323 | 1.0 | 0.007 | -76.5 | 92.2 | ||
| af-p50993-f1 | 1 | P50993 | 86.71 | 0.0 | PRO | A:331 | A:331 | 1.0 | 0.007 | -76.3 | 92.3 | ||