Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 116937743 . C A CCDS887.1:NM_000701.7:c.1672Ctc>Atc_NP_000692.2:p.558L>I Homo sapiens ATPase Na+/K+ transporting subunit alpha 1 (ATP1A1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4hqj 1 P05024 98.14 0.0 X-RAY
 2013-10-02 LEU A:556 A:551 28.0 0.165 E -153.1 111.3 28.0 0.165 0.0
LEU D:556 C:551 27.0 0.159 E -151.6 111.0 NA NA NA
4hyt 1 P05024 98.14 0.0 X-RAY
 2013-06-26 LEU A:556 A:551 25.0 0.147 E -145.7 131.9 25.0 0.147 0.0
LEU D:556 C:551 27.0 0.159 E -145.7 132.1 NA NA NA
4res 1 P05024 98.14 0.0 X-RAY
 2015-01-28 LEU A:556 A:551 32.0 0.188 E -142.4 128.1 32.0 0.188 0.0
LEU D:556 C:551 30.0 0.176 E -142.2 128.2 NA NA NA
4ret 1 P05024 98.14 0.0 X-RAY
 2015-01-28 LEU A:556 A:551 24.0 0.141 E -146.6 136.4 24.0 0.141 0.0
LEU D:556 C:551 22.0 0.129 E -146.4 136.6 NA NA NA
7evx 1 P05024 98.14 0.0 X-RAY
 2021-07-07 LEU A:556 A:551 21.0 0.124 E -158.3 147.2 21.0 0.124 0.0
LEU D:556 C:551 21.0 0.124 E -157.8 145.9 NA NA NA
3wgu 1 I7HD36 98.62 0.0 X-RAY
 2013-10-09 LEU A:551 A:551 24.0 0.141 E -146.2 130.1 24.0 0.141 0.0 HOH
 9.196
 CD1
 O
LEU D:551 C:551 24.0 0.141 E -171.4 129.7 NA NA NA
3wgv 1 I7HD36 98.62 0.0 X-RAY
 2013-10-09 LEU A:551 A:551 26.0 0.153 E -143.3 127.7 26.0 0.153 0.0 HOH
 9.060
 CD1
 O
LEU D:551 C:551 21.0 0.124 E -171.8 126.8 NA NA NA
7d91 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:551 A:551 28.0 0.165 E -149.3 138.8 28.0 0.165 0.0
7d92 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:551 A:551 29.0 0.171 E -152.3 136.2 29.0 0.171 0.0
7d93 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:551 A:551 24.0 0.141 E -158.0 147.1 24.0 0.141 0.0
LEU C:551 C:551 23.0 0.135 E -157.0 145.6 NA NA NA
7d94 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:551 A:551 24.0 0.141 E -158.2 147.0 24.0 0.141 0.0
LEU D:551 C:551 23.0 0.135 E -157.6 146.0 NA NA NA
7ddf 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:551 A:551 22.0 0.129 E -148.8 142.7 22.0 0.129 0.0
LEU D:551 C:551 24.0 0.141 E -148.8 142.5 NA NA NA
7ddh 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:551 A:551 22.0 0.129 E -149.8 143.6 22.0 0.129 0.0
LEU D:551 C:551 21.0 0.124 E -149.4 142.9 NA NA NA
7ddi 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:551 A:551 23.0 0.135 E -160.6 147.4 23.0 0.135 0.0
LEU D:551 C:551 21.0 0.124 E -160.3 146.5 NA NA NA
7ddj 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:551 A:551 24.0 0.141 E -158.3 147.3 24.0 0.141 0.0
LEU D:551 C:551 23.0 0.135 E -157.5 146.3 NA NA NA
7ddk 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:551 A:551 21.0 0.124 E -158.4 145.2 21.0 0.124 0.0
LEU D:551 C:551 21.0 0.124 E -158.1 144.5 NA NA NA
7ddl 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:551 A:551 24.0 0.141 E -157.9 147.2 24.0 0.141 0.0
LEU D:551 C:551 24.0 0.141 E -157.6 146.5 NA NA NA
4xe5 1 Q08DA1 97.46 0.0 X-RAY
 2016-03-09 LEU A:556 A:556 26.0 0.153 E -141.0 122.8 26.0 0.153 0.0
3b8e 1 P05024 98.4 0.0 X-RAY
 2007-12-18 LEU A:533 A:551 27.0 0.159 E -151.7 143.0 27.0 0.159 0.0
LEU D:533 C:551 28.0 0.165 E -152.1 143.0 NA NA NA
3kdp 1 P05024 98.4 0.0 X-RAY
 2010-02-16 LEU A:533 A:551 25.0 0.147 E -145.7 130.4 25.0 0.147 0.0
LEU D:533 C:551 25.0 0.147 E -142.1 128.1 NA NA NA
3n23 1 P05024 98.59 0.0 X-RAY
 2011-01-19 LEU A:527 A:551 26.0 0.153 E -149.2 138.8 26.0 0.153 0.0
LEU D:527 C:551 25.0 0.147 E -143.5 134.3 NA NA NA
2zxe 1 Q4H132 87.84 0.0 X-RAY
 2009-05-19 PHE A:563 A:558 52.0 0.248 E -155.7 117.2 52.0 0.248 0.0 HOH
 6.716
 N
 O
3a3y 1 Q4H132 87.84 0.0 X-RAY
 2009-09-08 PHE A:563 A:558 47.0 0.224 E -154.1 117.6 47.0 0.224 0.0
5avq 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 52.0 0.248 E -155.7 117.2 52.0 0.248 0.0
5avr 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 52.0 0.248 E -155.7 117.2 52.0 0.248 0.0
5avs 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 51.0 0.243 E -155.7 117.3 51.0 0.243 0.0
5avt 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 51.0 0.243 E -155.7 117.2 51.0 0.243 0.0
5avu 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 51.0 0.243 E -155.7 117.3 51.0 0.243 0.0
5avv 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 51.0 0.243 E -155.7 117.2 51.0 0.243 0.0
5avw 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 51.0 0.243 E -155.7 117.3 51.0 0.243 0.0
5avx 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 51.0 0.243 E -155.7 117.2 51.0 0.243 0.0
5avy 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 51.0 0.243 E -155.7 117.2 51.0 0.243 0.0
5avz 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 51.0 0.243 E -155.7 117.2 51.0 0.243 0.0
5aw0 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 51.0 0.243 E -155.7 117.2 51.0 0.243 0.0
5aw1 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 51.0 0.243 E -155.7 117.2 51.0 0.243 0.0
5aw2 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 51.0 0.243 E -155.6 117.2 51.0 0.243 0.0
5aw3 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 51.0 0.243 E -155.7 117.3 51.0 0.243 0.0
5aw4 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 52.0 0.248 E -155.7 117.3 52.0 0.248 0.0
5aw5 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 51.0 0.243 E -155.7 117.2 51.0 0.243 0.0
5aw6 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 52.0 0.248 E -155.7 117.2 52.0 0.248 0.0
5aw7 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 52.0 0.248 E -155.7 117.3 52.0 0.248 0.0
5aw8 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 52.0 0.248 E -155.7 117.3 52.0 0.248 0.0
5aw9 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 PHE A:563 A:558 49.0 0.233 E -151.7 115.8 49.0 0.233 0.0 HOH
 6.704
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05023-f1 1 P05023 100.0 0.0 LEU A:558 A:558 32.0 0.188 E -148.6 132.3
af-p13637-f1 1 P13637 87.88 0.0 TYR A:548 A:548 64.0 0.278 E -155.5 133.2
af-p50993-f1 1 P50993 86.71 0.0 LEU A:555 A:555 36.0 0.212 E -144.8 126.0