Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 116937809 . A C CCDS887.1:NM_000701.7:c.1738Atc>Ctc_NP_000692.2:p.580I>L Homo sapiens ATPase Na+/K+ transporting subunit alpha 1 (ATP1A1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4hqj 1 P05024 98.14 0.0 X-RAY
 2013-10-02 LEU A:578 A:573 21.0 0.124 -99.5 4.0 21.0 0.124 0.0
LEU D:578 C:573 21.0 0.124 -99.3 4.4 NA NA NA
4hyt 1 P05024 98.14 0.0 X-RAY
 2013-06-26 LEU A:578 A:573 42.0 0.247 S -57.4 -10.3 42.0 0.247 0.0
LEU D:578 C:573 34.0 0.2 -99.6 -6.2 NA NA NA
4res 1 P05024 98.14 0.0 X-RAY
 2015-01-28 LEU A:578 A:573 48.0 0.282 -96.2 -3.7 48.0 0.282 0.0
LEU D:578 C:573 47.0 0.276 -77.6 -7.8 NA NA NA
4ret 1 P05024 98.14 0.0 X-RAY
 2015-01-28 LEU A:578 A:573 41.0 0.241 S -58.9 -12.1 41.0 0.241 0.0
LEU D:578 C:573 41.0 0.241 S -59.1 -11.9 NA NA NA
7evx 1 P05024 98.14 0.0 X-RAY
 2021-07-07 LEU A:578 A:573 76.0 0.447 S -60.6 -42.8 76.0 0.447 0.0
LEU D:578 C:573 82.0 0.482 S -60.5 -43.0 NA NA NA
3wgu 1 I7HD36 98.62 0.0 X-RAY
 2013-10-09 LEU A:573 A:573 39.0 0.229 S -107.6 -9.7 39.0 0.229 0.0 HOH
 8.506
 C
 O
LEU D:573 C:573 32.0 0.188 S -108.5 2.8 NA NA NA
3wgv 1 I7HD36 98.62 0.0 X-RAY
 2013-10-09 LEU A:573 A:573 41.0 0.241 -104.0 -11.8 41.0 0.241 0.0 HOH
 8.346
 C
 O
LEU D:573 C:573 34.0 0.2 S -107.4 3.8 NA NA NA
7d91 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:573 A:573 46.0 0.271 S -64.0 -32.8 46.0 0.271 0.0
7d92 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:573 A:573 50.0 0.294 S -67.3 -31.7 50.0 0.294 0.0
7d93 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:573 A:573 82.0 0.482 S -62.6 -42.9 82.0 0.482 0.0
LEU C:573 C:573 88.0 0.518 S -61.9 -44.9 NA NA NA
7d94 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:573 A:573 82.0 0.482 S -62.3 -43.7 82.0 0.482 0.0
LEU D:573 C:573 85.0 0.5 S -61.3 -44.1 NA NA NA
7ddf 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:573 A:573 75.0 0.441 S -63.7 -39.1 75.0 0.441 0.0
LEU D:573 C:573 89.0 0.524 S -62.6 -41.3 NA NA NA
7ddh 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:573 A:573 74.0 0.435 S -63.9 -38.3 74.0 0.435 0.0
LEU D:573 C:573 78.0 0.459 S -63.5 -38.7 NA NA NA
7ddi 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:573 A:573 73.0 0.429 S -62.1 -37.2 73.0 0.429 0.0
LEU D:573 C:573 78.0 0.459 S -61.7 -38.1 NA NA NA
7ddj 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:573 A:573 83.0 0.488 S -62.1 -43.1 83.0 0.488 0.0
LEU D:573 C:573 84.0 0.494 S -61.7 -44.3 NA NA NA
7ddk 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:573 A:573 83.0 0.488 S -59.8 -41.8 83.0 0.488 0.0
LEU D:573 C:573 87.0 0.512 S -59.5 -42.7 NA NA NA
7ddl 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:573 A:573 81.0 0.476 S -62.2 -43.4 81.0 0.476 0.0
LEU D:573 C:573 83.0 0.488 S -61.2 -44.1 NA NA NA
4xe5 1 Q08DA1 97.46 0.0 X-RAY
 2016-03-09 VAL A:578 A:578 30.0 0.194 S -52.5 -26.4 30.0 0.194 0.0
3b8e 1 P05024 98.4 0.0 X-RAY
 2007-12-18 LEU A:555 A:573 36.0 0.212 -142.0 -30.8 36.0 0.212 0.0
LEU D:555 C:573 37.0 0.218 -141.4 -30.2 NA NA NA
3kdp 1 P05024 98.4 0.0 X-RAY
 2010-02-16 LEU A:555 A:573 22.0 0.129 -137.5 18.6 22.0 0.129 0.0
LEU D:555 C:573 22.0 0.129 -136.5 20.7 NA NA NA
3n23 1 P05024 98.59 0.0 X-RAY
 2011-01-19 LEU A:549 A:573 28.0 0.165 -109.0 -21.8 28.0 0.165 0.0
LEU D:549 C:573 28.0 0.165 -109.4 -21.3 NA NA NA
2zxe 1 Q4H132 87.84 0.0 X-RAY
 2009-05-19 THR A:585 A:580 21.0 0.15 -122.7 14.2 21.0 0.15 0.0
3a3y 1 Q4H132 87.84 0.0 X-RAY
 2009-09-08 THR A:585 A:580 18.0 0.129 -128.3 10.3 18.0 0.129 0.0
5avq 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 21.0 0.15 -122.6 14.1 21.0 0.15 0.0
5avr 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 21.0 0.15 -122.6 14.2 21.0 0.15 0.0
5avs 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 21.0 0.15 -122.7 14.2 21.0 0.15 0.0
5avt 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 21.0 0.15 -122.7 14.2 21.0 0.15 0.0
5avu 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 21.0 0.15 -122.7 14.2 21.0 0.15 0.0
5avv 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 21.0 0.15 -122.7 14.1 21.0 0.15 0.0
5avw 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 21.0 0.15 -122.7 14.2 21.0 0.15 0.0
5avx 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 22.0 0.157 -122.6 14.2 22.0 0.157 0.0
5avy 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 22.0 0.157 -122.7 14.2 22.0 0.157 0.0
5avz 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 21.0 0.15 -122.7 14.2 21.0 0.15 0.0
5aw0 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 21.0 0.15 -122.6 14.2 21.0 0.15 0.0
5aw1 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 22.0 0.157 -122.7 14.1 22.0 0.157 0.0
5aw2 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 21.0 0.15 -122.7 14.2 21.0 0.15 0.0
5aw3 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 21.0 0.15 -122.7 14.3 21.0 0.15 0.0
5aw4 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 21.0 0.15 -122.8 14.2 21.0 0.15 0.0
5aw5 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 21.0 0.15 -122.7 14.1 21.0 0.15 0.0
5aw6 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 21.0 0.15 -122.7 14.1 21.0 0.15 0.0
5aw7 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 21.0 0.15 -122.7 14.3 21.0 0.15 0.0
5aw8 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 21.0 0.15 -122.7 14.1 21.0 0.15 0.0
5aw9 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 THR A:585 A:580 19.0 0.136 -122.1 6.3 19.0 0.136 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05023-f1 1 P05023 100.0 0.0 ILE A:580 A:580 42.0 0.24 -111.4 -4.3
af-p13637-f1 1 P13637 87.88 0.0 THR A:570 A:570 23.0 0.164 -111.0 1.4
af-p50993-f1 1 P50993 86.71 0.0 THR A:577 A:577 23.0 0.164 -116.5 13.4