Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 116939323 | . | G | A | CCDS887.1:NM_000701.7:c.1940cGc>cAc_NP_000692.2:p.647R>H | Homo sapiens ATPase Na+/K+ transporting subunit alpha 1 (ATP1A1), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
4hqj | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2013-10-02 | ARG | A:645 | A:640 | 142.0 | 0.631 | H | -53.8 | -39.8 | 142.0 | 0.631 | 0.0 | ||||||
ARG | D:645 | C:640 | 144.0 | 0.64 | H | -53.8 | -39.7 | NA | NA | NA | |||||||||||||
4hyt | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2013-06-26 | ARG | A:645 | A:640 | 142.0 | 0.631 | H | -59.1 | -42.9 | 142.0 | 0.631 | 0.0 | ||||||
ARG | D:645 | C:640 | 164.0 | 0.729 | H | -65.1 | -28.5 | NA | NA | NA | |||||||||||||
4res | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2015-01-28 | ARG | A:645 | A:640 | 195.0 | 0.867 | H | -72.4 | -25.0 | 195.0 | 0.867 | 0.0 | ||||||
ARG | D:645 | C:640 | 191.0 | 0.849 | H | -72.4 | -24.8 | NA | NA | NA | |||||||||||||
4ret | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2015-01-28 | ARG | A:645 | A:640 | 143.0 | 0.636 | H | -63.9 | -39.5 | 143.0 | 0.636 | 0.0 | ||||||
ARG | D:645 | C:640 | 142.0 | 0.631 | H | -63.4 | -39.9 | NA | NA | NA | |||||||||||||
7evx | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2021-07-07 | ARG | A:645 | A:640 | 152.0 | 0.676 | H | -72.8 | -27.2 | 152.0 | 0.676 | 0.0 | ||||||
ARG | D:645 | C:640 | 156.0 | 0.693 | H | -71.4 | -28.6 | NA | NA | NA | |||||||||||||
3wgu | 1 | I7HD36 | 98.62 | 0.0 |
X-RAY |
2013-10-09 | ARG | A:640 | A:640 | 140.0 | 0.622 | H | -73.9 | -39.3 | 140.0 | 0.622 | 0.0 | ||||||
ARG | D:640 | C:640 | 145.0 | 0.644 | H | -87.8 | -22.1 | NA | NA | NA | |||||||||||||
3wgv | 1 | I7HD36 | 98.62 | 0.0 |
X-RAY |
2013-10-09 | ARG | A:640 | A:640 | 141.0 | 0.627 | H | -65.1 | -39.0 | 141.0 | 0.627 | 0.0 | ||||||
ARG | D:640 | C:640 | 147.0 | 0.653 | H | -73.8 | -23.8 | NA | NA | NA | |||||||||||||
7d91 | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:640 | A:640 | 156.0 | 0.693 | H | -74.1 | -21.6 | 156.0 | 0.693 | 0.0 | ||||||
7d92 | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:640 | A:640 | 154.0 | 0.684 | H | -72.6 | -21.4 | 154.0 | 0.684 | 0.0 | ||||||
7d93 | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:640 | A:640 | 159.0 | 0.707 | H | -73.4 | -27.6 | 159.0 | 0.707 | 0.0 | ||||||
ARG | C:640 | C:640 | 147.0 | 0.653 | H | -71.9 | -24.7 | NA | NA | NA | |||||||||||||
7d94 | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:640 | A:640 | 162.0 | 0.72 | H | -73.8 | -26.9 | 162.0 | 0.72 | 0.0 | ||||||
ARG | D:640 | C:640 | 147.0 | 0.653 | H | -73.0 | -24.6 | NA | NA | NA | |||||||||||||
7ddf | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:640 | A:640 | 152.0 | 0.676 | H | -77.2 | -28.8 | 152.0 | 0.676 | 0.0 | ||||||
ARG | D:640 | C:640 | 151.0 | 0.671 | H | -76.9 | -27.9 | NA | NA | NA | |||||||||||||
7ddh | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:640 | A:640 | 161.0 | 0.716 | H | -79.2 | -26.7 | 161.0 | 0.716 | 0.0 | ||||||
ARG | D:640 | C:640 | 155.0 | 0.689 | H | -77.8 | -28.1 | NA | NA | NA | |||||||||||||
7ddi | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:640 | A:640 | 152.0 | 0.676 | H | -68.3 | -32.7 | 152.0 | 0.676 | 0.0 | ||||||
ARG | D:640 | C:640 | 145.0 | 0.644 | H | -68.0 | -32.7 | NA | NA | NA | |||||||||||||
7ddj | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:640 | A:640 | 159.0 | 0.707 | H | -72.5 | -27.2 | 159.0 | 0.707 | 0.0 | ||||||
ARG | D:640 | C:640 | 147.0 | 0.653 | H | -72.0 | -24.8 | NA | NA | NA | |||||||||||||
7ddk | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:640 | A:640 | 150.0 | 0.667 | H | -70.4 | -26.3 | 150.0 | 0.667 | 0.0 | ||||||
ARG | D:640 | C:640 | 152.0 | 0.676 | H | -71.5 | -26.9 | NA | NA | NA | |||||||||||||
7ddl | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:640 | A:640 | 158.0 | 0.702 | H | -73.8 | -27.9 | 158.0 | 0.702 | 0.0 | ||||||
ARG | D:640 | C:640 | 147.0 | 0.653 | H | -72.8 | -26.0 | NA | NA | NA | |||||||||||||
4xe5 | 1 | Q08DA1 | 97.46 | 0.0 |
X-RAY |
2016-03-09 | ARG | A:645 | A:645 | 146.0 | 0.649 | H | -74.7 | -33.5 | 146.0 | 0.649 | 0.0 | ||||||
3b8e | 1 | P05024 | 98.4 | 0.0 |
X-RAY |
2007-12-18 | ARG | A:622 | A:640 | 158.0 | 0.702 | S | -54.3 | 56.0 | 158.0 | 0.702 | 0.0 | ||||||
ARG | D:622 | C:640 | 160.0 | 0.711 | S | -54.0 | 55.8 | NA | NA | NA | |||||||||||||
3kdp | 1 | P05024 | 98.4 | 0.0 |
X-RAY |
2010-02-16 | ARG | A:622 | A:640 | 142.0 | 0.631 | T | -113.8 | 11.1 | 142.0 | 0.631 | 0.0 | ||||||
ARG | D:622 | C:640 | 138.0 | 0.613 | T | -114.3 | 11.7 | NA | NA | NA | |||||||||||||
3n23 | 1 | P05024 | 98.59 | 0.0 |
X-RAY |
2011-01-19 | ARG | A:616 | A:640 | 139.0 | 0.618 | H | -62.4 | -58.1 | 139.0 | 0.618 | 0.0 | ||||||
ARG | D:616 | C:640 | 138.0 | 0.613 | H | -62.3 | -58.3 | NA | NA | NA | |||||||||||||
2zxe | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2009-05-19 | ARG | A:652 | A:647 | 152.0 | 0.676 | H | -61.5 | -54.1 | 152.0 | 0.676 | 0.0 |
HOH |
6.986 |
N |
O |
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3a3y | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2009-09-08 | ARG | A:652 | A:647 | 150.0 | 0.667 | H | -58.6 | -50.9 | 150.0 | 0.667 | 0.0 |
HOH |
6.367 |
N |
O |
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5avq | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 152.0 | 0.676 | H | -61.5 | -54.2 | 152.0 | 0.676 | 0.0 | ||||||
5avr | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 152.0 | 0.676 | H | -61.4 | -54.1 | 152.0 | 0.676 | 0.0 | ||||||
5avs | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 152.0 | 0.676 | H | -61.4 | -54.0 | 152.0 | 0.676 | 0.0 | ||||||
5avt | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 152.0 | 0.676 | H | -61.5 | -54.1 | 152.0 | 0.676 | 0.0 | ||||||
5avu | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 153.0 | 0.68 | H | -61.5 | -54.0 | 153.0 | 0.68 | 0.0 | ||||||
5avv | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 152.0 | 0.676 | H | -61.6 | -54.1 | 152.0 | 0.676 | 0.0 | ||||||
5avw | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 152.0 | 0.676 | H | -61.5 | -54.1 | 152.0 | 0.676 | 0.0 | ||||||
5avx | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 152.0 | 0.676 | H | -61.5 | -54.2 | 152.0 | 0.676 | 0.0 | ||||||
5avy | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 152.0 | 0.676 | H | -61.4 | -54.2 | 152.0 | 0.676 | 0.0 | ||||||
5avz | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 152.0 | 0.676 | H | -61.4 | -54.2 | 152.0 | 0.676 | 0.0 | ||||||
5aw0 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 152.0 | 0.676 | H | -61.5 | -54.1 | 152.0 | 0.676 | 0.0 | ||||||
5aw1 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 151.0 | 0.671 | H | -61.6 | -54.0 | 151.0 | 0.671 | 0.0 | ||||||
5aw2 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 152.0 | 0.676 | H | -61.5 | -54.1 | 152.0 | 0.676 | 0.0 | ||||||
5aw3 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 152.0 | 0.676 | H | -61.5 | -54.2 | 152.0 | 0.676 | 0.0 | ||||||
5aw4 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 152.0 | 0.676 | H | -61.5 | -54.2 | 152.0 | 0.676 | 0.0 | ||||||
5aw5 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 152.0 | 0.676 | H | -61.5 | -54.1 | 152.0 | 0.676 | 0.0 | ||||||
5aw6 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 152.0 | 0.676 | H | -61.4 | -54.2 | 152.0 | 0.676 | 0.0 | ||||||
5aw7 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 152.0 | 0.676 | H | -61.4 | -54.2 | 152.0 | 0.676 | 0.0 | ||||||
5aw8 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 153.0 | 0.68 | H | -61.5 | -54.1 | 153.0 | 0.68 | 0.0 | ||||||
5aw9 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:652 | A:647 | 151.0 | 0.671 | H | -54.2 | -55.9 | 151.0 | 0.671 | 0.0 |
HOH |
6.919 |
N |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p05023-f1 | 1 | P05023 | 100.0 | 0.0 | ARG | A:647 | A:647 | 142.0 | 0.631 | H | -64.4 | -41.4 | |
af-p13637-f1 | 1 | P13637 | 87.88 | 0.0 | ARG | A:637 | A:637 | 143.0 | 0.636 | H | -64.5 | -41.2 | |
af-p50993-f1 | 1 | P50993 | 86.71 | 0.0 | ARG | A:644 | A:644 | 144.0 | 0.64 | H | -64.9 | -42.3 |