Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 116943486 | . | T | A | CCDS887.1:NM_000701.7:c.2576aTg>aAg_NP_000692.2:p.859M>K | Homo sapiens ATPase Na+/K+ transporting subunit alpha 1 (ATP1A1), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4hqj | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2013-10-02 | MET | A:857 | A:852 | 83.0 | 0.449 | H | -58.8 | -44.3 | 52.0 | 0.281 | 0.168 |
B:P05027:0.168 |
NA |
8.434 |
N |
NA |
|
| MET | D:857 | C:852 | 82.0 | 0.443 | H | -58.9 | -44.6 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2013-06-26 | MET | A:857 | A:852 | 80.0 | 0.432 | H | -66.7 | -47.8 | 39.0 | 0.211 | 0.221 |
B:P05027:0.222 |
17F CE1 17F |
9.337 9.782 5.346 |
CE C CE |
O10 C1 C32 |
|
| MET | D:857 | C:852 | 80.0 | 0.432 | H | -66.5 | -47.7 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2015-01-28 | MET | A:857 | A:852 | 73.0 | 0.395 | H | -62.7 | -42.9 | 34.0 | 0.184 | 0.211 |
B:P05027:0.211 |
|||||
| MET | D:857 | C:852 | 75.0 | 0.405 | H | -63.1 | -43.0 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2015-01-28 | MET | A:857 | A:852 | 78.0 | 0.422 | H | -67.5 | -48.4 | 39.0 | 0.211 | 0.211 |
B:P05027:0.211 |
17F |
3.695 |
CE |
C31 |
|
| MET | D:857 | C:852 | 79.0 | 0.427 | H | -67.0 | -48.6 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2021-07-07 | MET | A:857 | A:852 | 75.0 | 0.405 | H | -65.1 | -42.7 | 36.0 | 0.195 | 0.21 |
B:P05027:0.211 |
CLR |
5.094 |
CE |
C18 |
|
| MET | D:857 | C:852 | 76.0 | 0.411 | H | -64.1 | -43.5 | NA | NA | NA | |||||||||||||
| 3wgu | 1 | I7HD36 | 98.62 | 0.0 |
X-RAY |
2013-10-09 | MET | A:852 | A:852 | 85.0 | 0.459 | H | -72.6 | -51.7 | 45.0 | 0.243 | 0.216 |
B:P05027:0.216 |
PC1 CLR |
6.980 3.907 |
CE CE |
C3B C23 |
|
| MET | D:852 | C:852 | 84.0 | 0.454 | H | -72.6 | -44.4 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 98.62 | 0.0 |
X-RAY |
2013-10-09 | MET | A:852 | A:852 | 84.0 | 0.454 | H | -71.8 | -50.1 | 47.0 | 0.254 | 0.2 |
B:P05027:0.2 |
CLR PC1 |
3.759 6.786 |
CE CE |
C23 C3C |
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| MET | D:852 | C:852 | 89.0 | 0.481 | H | -67.5 | -29.4 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | MET | A:852 | A:852 | 84.0 | 0.454 | H | -62.9 | -42.9 | 41.0 | 0.222 | 0.232 |
B:P05027:0.232 |
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| 7d92 | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | MET | A:852 | A:852 | 85.0 | 0.459 | H | -63.6 | -42.6 | 43.0 | 0.232 | 0.227 |
B:P05027:0.227 |
CLR |
3.808 |
CE |
C23 |
|
| 7d93 | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | MET | A:852 | A:852 | 81.0 | 0.438 | H | -65.0 | -44.7 | 38.0 | 0.205 | 0.233 |
B:P05027:0.232 |
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| MET | C:852 | C:852 | 81.0 | 0.438 | H | -64.2 | -45.2 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | MET | A:852 | A:852 | 81.0 | 0.438 | H | -65.6 | -45.2 | 41.0 | 0.222 | 0.216 |
B:P05027:0.216 |
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| MET | D:852 | C:852 | 86.0 | 0.465 | H | -64.6 | -46.2 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | MET | A:852 | A:852 | 81.0 | 0.438 | H | -66.7 | -46.6 | 38.0 | 0.205 | 0.233 |
B:P05027:0.232 |
CLR |
4.856 |
CE |
C18 |
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| MET | D:852 | C:852 | 79.0 | 0.427 | H | -66.8 | -43.6 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | MET | A:852 | A:852 | 80.0 | 0.432 | H | -66.7 | -45.1 | 41.0 | 0.222 | 0.21 |
B:P05027:0.211 |
CLR |
4.769 |
CE |
C18 |
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| MET | D:852 | C:852 | 86.0 | 0.465 | H | -66.4 | -44.3 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | MET | A:852 | A:852 | 79.0 | 0.427 | H | -65.9 | -45.9 | 41.0 | 0.222 | 0.205 |
B:P05027:0.205 |
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| MET | D:852 | C:852 | 80.0 | 0.432 | H | -64.9 | -46.3 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | MET | A:852 | A:852 | 78.0 | 0.422 | H | -65.3 | -45.8 | 37.0 | 0.2 | 0.222 |
B:P05027:0.222 |
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| MET | D:852 | C:852 | 83.0 | 0.449 | H | -65.1 | -45.4 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | MET | A:852 | A:852 | 79.0 | 0.427 | H | -66.4 | -43.7 | 40.0 | 0.216 | 0.211 |
B:P05027:0.211 |
CLR |
5.185 |
CE |
C15 |
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| MET | D:852 | C:852 | 80.0 | 0.432 | H | -65.9 | -43.5 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | MET | A:852 | A:852 | 81.0 | 0.438 | H | -65.5 | -45.3 | 40.0 | 0.216 | 0.222 |
B:P05027:0.222 |
CLR |
5.148 |
CE |
C18 |
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| MET | D:852 | C:852 | 82.0 | 0.443 | H | -64.7 | -45.9 | NA | NA | NA | |||||||||||||
| 4xe5 | 1 | Q08DA1 | 97.46 | 0.0 |
X-RAY |
2016-03-09 | MET | A:857 | A:857 | 83.0 | 0.449 | H | -67.1 | -43.6 | 41.0 | 0.222 | 0.227 |
B:G3MWR4:0.227 |
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| 3b8e | 1 | P05024 | 98.4 | 0.0 |
X-RAY |
2007-12-18 | MET | A:834 | A:852 | 82.0 | 0.443 | H | -75.1 | -64.9 | 33.0 | 0.178 | 0.265 |
B:P05027:0.265 |
PC1 |
5.857 |
SD |
O12 |
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| MET | D:834 | C:852 | 93.0 | 0.503 | H | -85.9 | -61.0 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 98.4 | 0.0 |
X-RAY |
2010-02-16 | MET | A:834 | A:852 | 91.0 | 0.492 | H | -59.2 | -59.5 | 48.0 | 0.259 | 0.233 |
B:P05027:0.232 |
CLR |
3.962 |
CE |
C26 |
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| MET | D:834 | C:852 | 88.0 | 0.476 | H | -61.2 | -60.0 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 98.59 | 0.0 |
X-RAY |
2011-01-19 | MET | A:828 | A:852 | 76.0 | 0.411 | H | -59.0 | -50.5 | 34.0 | 0.184 | 0.227 |
B:P05027:0.227 |
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| MET | D:828 | C:852 | 77.0 | 0.416 | H | -58.4 | -50.4 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2009-05-19 | MET | A:864 | A:859 | 88.0 | 0.476 | H | -68.3 | -43.6 | 50.0 | 0.27 | 0.206 |
B:None:0.205 |
CLR |
4.043 |
CE |
C23 |
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| 3a3y | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2009-09-08 | MET | A:864 | A:859 | 80.0 | 0.432 | H | -72.3 | -42.9 | 48.0 | 0.259 | 0.173 |
B:None:0.173 |
CLR |
4.087 |
CE |
C23 |
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| 5avq | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 88.0 | 0.476 | H | -68.3 | -43.6 | 51.0 | 0.276 | 0.2 |
B:C4IX13:0.2 |
CLR |
4.043 |
CE |
C23 |
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| 5avr | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 87.0 | 0.47 | H | -68.3 | -43.6 | 51.0 | 0.276 | 0.194 |
B:C4IX13:0.195 |
CLR |
4.044 |
CE |
C23 |
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| 5avs | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 88.0 | 0.476 | H | -68.3 | -43.6 | 50.0 | 0.27 | 0.206 |
B:C4IX13:0.205 |
CLR |
4.043 |
CE |
C23 |
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| 5avt | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 88.0 | 0.476 | H | -68.3 | -43.6 | 50.0 | 0.27 | 0.206 |
B:C4IX13:0.205 |
CLR |
4.042 |
CE |
C23 |
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| 5avu | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 88.0 | 0.476 | H | -68.3 | -43.6 | 51.0 | 0.276 | 0.2 |
B:C4IX13:0.2 |
CLR |
4.043 |
CE |
C23 |
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| 5avv | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 87.0 | 0.47 | H | -68.2 | -43.7 | 50.0 | 0.27 | 0.2 |
B:C4IX13:0.2 |
CLR |
4.043 |
CE |
C23 |
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| 5avw | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 87.0 | 0.47 | H | -68.3 | -43.6 | 51.0 | 0.276 | 0.194 |
B:C4IX13:0.195 |
CLR |
4.043 |
CE |
C23 |
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| 5avx | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 87.0 | 0.47 | H | -68.4 | -43.5 | 50.0 | 0.27 | 0.2 |
B:C4IX13:0.2 |
CLR |
4.044 |
CE |
C23 |
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| 5avy | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 87.0 | 0.47 | H | -68.3 | -43.6 | 49.0 | 0.265 | 0.205 |
B:C4IX13:0.205 |
CLR |
4.042 |
CE |
C23 |
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| 5avz | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 88.0 | 0.476 | H | -68.3 | -43.4 | 49.0 | 0.265 | 0.211 |
B:C4IX13:0.211 |
CLR |
4.042 |
CE |
C23 |
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| 5aw0 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 87.0 | 0.47 | H | -68.2 | -43.6 | 50.0 | 0.27 | 0.2 |
B:C4IX13:0.2 |
CLR |
4.043 |
CE |
C23 |
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| 5aw1 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 87.0 | 0.47 | H | -68.3 | -43.6 | 50.0 | 0.27 | 0.2 |
B:C4IX13:0.2 |
CLR |
4.044 |
CE |
C23 |
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| 5aw2 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 87.0 | 0.47 | H | -68.3 | -43.6 | 52.0 | 0.281 | 0.189 |
B:C4IX13:0.189 |
CLR |
4.043 |
CE |
C23 |
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| 5aw3 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 87.0 | 0.47 | H | -68.4 | -43.6 | 49.0 | 0.265 | 0.205 |
B:C4IX13:0.205 |
CLR |
4.042 |
CE |
C23 |
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| 5aw4 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 87.0 | 0.47 | H | -68.3 | -43.6 | 52.0 | 0.281 | 0.189 |
B:C4IX13:0.189 |
CLR |
4.042 |
CE |
C23 |
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| 5aw5 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 87.0 | 0.47 | H | -68.3 | -43.6 | 52.0 | 0.281 | 0.189 |
B:C4IX13:0.189 |
CLR |
4.042 |
CE |
C23 |
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| 5aw6 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 88.0 | 0.476 | H | -68.2 | -43.6 | 52.0 | 0.281 | 0.195 |
B:C4IX13:0.195 |
CLR |
4.041 |
CE |
C23 |
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| 5aw7 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 87.0 | 0.47 | H | -68.3 | -43.6 | 52.0 | 0.281 | 0.189 |
B:C4IX13:0.189 |
CLR |
4.042 |
CE |
C23 |
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| 5aw8 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 88.0 | 0.476 | H | -68.3 | -43.6 | 52.0 | 0.281 | 0.195 |
B:C4IX13:0.195 |
CLR |
4.043 |
CE |
C23 |
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| 5aw9 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | MET | A:864 | A:859 | 86.0 | 0.465 | H | -65.5 | -47.5 | 48.0 | 0.259 | 0.206 |
B:C4IX13:0.205 |
CLR |
3.690 |
CE |
C23 |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05023-f1 | 1 | P05023 | 100.0 | 0.0 | MET | A:859 | A:859 | 90.0 | 0.486 | H | -67.7 | -40.4 | |
| af-p13637-f1 | 1 | P13637 | 87.88 | 0.0 | MET | A:849 | A:849 | 93.0 | 0.503 | H | -68.1 | -39.9 | |
| af-p50993-f1 | 1 | P50993 | 86.71 | 0.0 | MET | A:856 | A:856 | 91.0 | 0.492 | H | -67.9 | -40.0 | |