Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 116943824 . T A CCDS887.1:NM_000701.7:c.2791Tgg>Agg_NP_000692.2:p.931W>R Homo sapiens ATPase Na+/K+ transporting subunit alpha 1 (ATP1A1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4hqj 1 P05024 98.14 0.0 X-RAY
 2013-10-02 TRP A:929 A:924 73.0 0.286 H -52.1 -59.4 73.0 0.286 0.0 NA
CLR
 7.434
3.332
 N
CG
 NA
C27
TRP D:929 C:924 71.0 0.278 H -52.0 -60.8 NA NA NA
4hyt 1 P05024 98.14 0.0 X-RAY
 2013-06-26 TRP A:929 A:924 61.0 0.239 H -61.9 -59.9 61.0 0.239 0.0 1AT
CLR
 9.281
3.549
 O
CZ3
 C4N
C24
TRP D:929 C:924 65.0 0.255 H -61.7 -59.7 NA NA NA
4res 1 P05024 98.14 0.0 X-RAY
 2015-01-28 TRP A:929 A:924 61.0 0.239 H -58.4 -61.1 61.0 0.239 0.0 CLR
 3.653
 CZ3
 C25
TRP D:929 C:924 59.0 0.231 H -57.2 -60.9 NA NA NA
4ret 1 P05024 98.14 0.0 X-RAY
 2015-01-28 TRP A:929 A:924 60.0 0.235 H -59.5 -60.3 60.0 0.235 0.0 CLR
 3.423
 CH2
 C23
TRP D:929 C:924 60.0 0.235 H -59.4 -60.1 NA NA NA
7evx 1 P05024 98.14 0.0 X-RAY
 2021-07-07 TRP A:929 A:924 54.0 0.212 H -59.7 -55.1 54.0 0.212 0.0 CLR
 3.791
 CH2
 C16
TRP D:929 C:924 57.0 0.224 H -59.0 -54.5 NA NA NA
3wgu 1 I7HD36 98.62 0.0 X-RAY
 2013-10-09 TRP A:924 A:924 62.0 0.243 H -63.0 -63.2 62.0 0.243 0.0 NA
CLR
 7.708
3.686
 N
CH2
 NA
C21
TRP D:924 C:924 65.0 0.255 H -56.2 -65.2 NA NA NA
3wgv 1 I7HD36 98.62 0.0 X-RAY
 2013-10-09 TRP A:924 A:924 64.0 0.251 H -67.2 -59.5 64.0 0.251 0.0 NA
CLR
 7.649
4.503
 N
CE3
 NA
C26
TRP D:924 C:924 70.0 0.275 H -53.7 -59.3 NA NA NA
7d91 1 P05024 98.13 0.0 X-RAY
 2021-01-27 TRP A:924 A:924 53.0 0.208 H -59.1 -56.9 53.0 0.208 0.0 CLR
 3.873
 CH2
 C16
7d92 1 P05024 98.13 0.0 X-RAY
 2021-01-27 TRP A:924 A:924 58.0 0.227 H -58.7 -57.2 58.0 0.227 0.0 CLR
 3.399
 CH2
 C16
7d93 1 P05024 98.13 0.0 X-RAY
 2021-01-27 TRP A:924 A:924 58.0 0.227 H -59.7 -55.7 58.0 0.227 0.0 CLR
 3.977
 CH2
 C16
TRP C:924 C:924 60.0 0.235 H -60.1 -54.3 NA NA NA
7d94 1 P05024 98.13 0.0 X-RAY
 2021-01-27 TRP A:924 A:924 60.0 0.235 H -58.8 -55.5 60.0 0.235 0.0 CLR
 3.919
 CH2
 C16
TRP D:924 C:924 62.0 0.243 H -59.7 -55.8 NA NA NA
7ddf 1 P05024 98.13 0.0 X-RAY
 2021-01-27 TRP A:924 A:924 65.0 0.255 H -58.6 -57.0 65.0 0.255 0.0 CLR
 3.769
 CZ3
 C24
TRP D:924 C:924 69.0 0.271 H -58.3 -57.0 NA NA NA
7ddh 1 P05024 98.13 0.0 X-RAY
 2021-01-27 TRP A:924 A:924 57.0 0.224 H -60.3 -58.7 57.0 0.224 0.0 CLR
 3.803
 CH2
 C16
TRP D:924 C:924 62.0 0.243 H -60.3 -57.2 NA NA NA
7ddi 1 P05024 98.13 0.0 X-RAY
 2021-01-27 TRP A:924 A:924 53.0 0.208 H -59.8 -62.0 53.0 0.208 0.0 CLR
 3.872
 CH2
 C16
TRP D:924 C:924 56.0 0.22 H -59.3 -62.0 NA NA NA
7ddj 1 P05024 98.13 0.0 X-RAY
 2021-01-27 TRP A:924 A:924 59.0 0.231 H -59.2 -54.8 59.0 0.231 0.0 CLR
 3.795
 CH2
 C16
TRP D:924 C:924 64.0 0.251 H -60.8 -53.7 NA NA NA
7ddk 1 P05024 98.13 0.0 X-RAY
 2021-01-27 TRP A:924 A:924 57.0 0.224 H -58.3 -60.1 57.0 0.224 0.0 CLR
 3.653
 CH2
 C16
TRP D:924 C:924 62.0 0.243 H -58.4 -60.7 NA NA NA
7ddl 1 P05024 98.13 0.0 X-RAY
 2021-01-27 TRP A:924 A:924 55.0 0.216 H -58.9 -56.4 55.0 0.216 0.0 CLR
 3.959
 CH2
 C16
TRP D:924 C:924 57.0 0.224 H -59.6 -56.1 NA NA NA
4xe5 1 Q08DA1 97.46 0.0 X-RAY
 2016-03-09 TRP A:929 A:929 68.0 0.267 H -58.9 -60.1 68.0 0.267 0.0 CLR
 3.498
 CH2
 C24
3b8e 1 P05024 98.4 0.0 X-RAY
 2007-12-18 TRP A:906 A:924 69.0 0.271 H -64.1 -77.1 69.0 0.271 0.0
TRP D:906 C:924 77.0 0.302 H -71.7 -72.8 NA NA NA
3kdp 1 P05024 98.4 0.0 X-RAY
 2010-02-16 TRP A:906 A:924 68.0 0.267 H -64.7 -68.3 68.0 0.267 0.0
TRP D:906 C:924 69.0 0.271 H -66.0 -67.5 NA NA NA
3n23 1 P05024 98.59 0.0 X-RAY
 2011-01-19 TRP A:900 A:924 80.0 0.314 H -59.3 -65.0 80.0 0.314 0.0
TRP D:900 C:924 79.0 0.31 H -58.8 -65.0 NA NA NA
2zxe 1 Q4H132 87.84 0.0 X-RAY
 2009-05-19 TRP A:936 A:931 61.0 0.239 H -54.8 -55.8 61.0 0.239 0.0 HOH
 4.078
 N
 O
3a3y 1 Q4H132 87.84 0.0 X-RAY
 2009-09-08 TRP A:936 A:931 62.0 0.243 H -55.2 -54.1 62.0 0.243 0.0 HOH
 3.767
 N
 O
5avq 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 61.0 0.239 H -54.8 -55.8 61.0 0.239 0.0
5avr 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 61.0 0.239 H -54.8 -55.8 61.0 0.239 0.0
5avs 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 61.0 0.239 H -54.8 -55.7 61.0 0.239 0.0
5avt 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 61.0 0.239 H -54.7 -55.8 61.0 0.239 0.0
5avu 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 61.0 0.239 H -54.8 -55.7 61.0 0.239 0.0
5avv 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 60.0 0.235 H -54.8 -55.7 60.0 0.235 0.0
5avw 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 61.0 0.239 H -54.8 -55.7 61.0 0.239 0.0
5avx 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 60.0 0.235 H -54.9 -55.7 60.0 0.235 0.0
5avy 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 60.0 0.235 H -54.7 -55.8 60.0 0.235 0.0
5avz 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 61.0 0.239 H -54.9 -55.7 61.0 0.239 0.0
5aw0 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 61.0 0.239 H -54.8 -55.8 61.0 0.239 0.0
5aw1 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 60.0 0.235 H -54.8 -55.8 60.0 0.235 0.0
5aw2 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 61.0 0.239 H -54.8 -55.7 61.0 0.239 0.0
5aw3 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 60.0 0.235 H -54.7 -55.8 60.0 0.235 0.0
5aw4 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 60.0 0.235 H -54.8 -55.7 60.0 0.235 0.0
5aw5 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 60.0 0.235 H -54.8 -55.9 60.0 0.235 0.0
5aw6 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 61.0 0.239 H -54.8 -55.7 61.0 0.239 0.0
5aw7 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 61.0 0.239 H -54.8 -55.8 61.0 0.239 0.0
5aw8 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 61.0 0.239 H -54.8 -55.8 61.0 0.239 0.0
5aw9 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 TRP A:936 A:931 62.0 0.243 H -58.3 -54.3 62.0 0.243 0.0 HOH
 3.827
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05023-f1 1 P05023 100.0 0.0 TRP A:931 A:931 54.0 0.212 H -57.6 -46.2
af-p13637-f1 1 P13637 87.88 0.0 TRP A:921 A:921 53.0 0.208 H -58.2 -46.9
af-p50993-f1 1 P50993 86.71 0.0 TRP A:928 A:928 53.0 0.208 H -58.5 -46.7