Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 116943830 | . | G | A | CCDS887.1:NM_000701.7:c.2797Gac>Aac_NP_000692.2:p.933D>N | Homo sapiens ATPase Na+/K+ transporting subunit alpha 1 (ATP1A1), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4hqj | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2013-10-02 | ASP | A:931 | A:926 | 0.0 | 0.0 | H | -56.5 | -37.5 | 0.0 | 0.0 | 0.0 |
NA NA CLR |
9.819 2.389 8.573 |
OD2 OD2 N |
NA NA C27 |
||
| ASP | D:931 | C:926 | 0.0 | 0.0 | H | -57.3 | -36.5 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2013-06-26 | ASP | A:931 | A:926 | 1.0 | 0.007 | H | -60.3 | -42.3 | 1.0 | 0.007 | 0.0 |
HOH |
9.300 |
OD2 |
O |
||
| ASP | D:931 | C:926 | 1.0 | 0.007 | H | -59.8 | -42.7 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2015-01-28 | ASP | A:931 | A:926 | 2.0 | 0.013 | H | -58.9 | -37.7 | 2.0 | 0.013 | 0.0 |
CLR K |
9.494 9.283 |
N OD2 |
C27 K |
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| ASP | D:931 | C:926 | 2.0 | 0.013 | H | -60.1 | -36.7 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2015-01-28 | ASP | A:931 | A:926 | 1.0 | 0.007 | H | -62.2 | -35.6 | 1.0 | 0.007 | 0.0 |
HOH |
9.256 |
OD2 |
O |
||
| ASP | D:931 | C:926 | 1.0 | 0.007 | H | -62.1 | -35.9 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 98.14 | 0.0 |
X-RAY |
2021-07-07 | ASP | A:931 | A:926 | 1.0 | 0.007 | H | -62.3 | -36.5 | 1.0 | 0.007 | 0.0 |
HOH |
9.515 |
OD2 |
O |
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| ASP | D:931 | C:926 | 1.0 | 0.007 | H | -62.8 | -37.2 | NA | NA | NA | |||||||||||||
| 3wgu | 1 | I7HD36 | 98.62 | 0.0 |
X-RAY |
2013-10-09 | ASP | A:926 | A:926 | 0.0 | 0.0 | H | -60.5 | -46.7 | 0.0 | 0.0 | 0.0 |
NA NA |
9.288 3.552 |
OD2 OD2 |
NA NA |
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| ASP | D:926 | C:926 | 1.0 | 0.007 | H | -55.1 | -50.4 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 98.62 | 0.0 |
X-RAY |
2013-10-09 | ASP | A:926 | A:926 | 1.0 | 0.007 | H | -64.4 | -44.7 | 1.0 | 0.007 | 0.0 |
NA NA |
9.309 3.339 |
OD2 OD2 |
NA NA |
||
| ASP | D:926 | C:926 | 1.0 | 0.007 | H | -57.1 | -49.9 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:926 | A:926 | 0.0 | 0.0 | H | -63.9 | -37.7 | 0.0 | 0.0 | 0.0 | ||||||
| 7d92 | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:926 | A:926 | 0.0 | 0.0 | H | -64.0 | -39.8 | 0.0 | 0.0 | 0.0 |
HOH |
9.894 |
OD2 |
O |
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| 7d93 | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:926 | A:926 | 1.0 | 0.007 | H | -64.6 | -35.1 | 1.0 | 0.007 | 0.0 |
HOH |
9.881 |
OD2 |
O |
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| ASP | C:926 | C:926 | 1.0 | 0.007 | H | -64.0 | -36.1 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:926 | A:926 | 0.0 | 0.0 | H | -64.2 | -36.2 | 0.0 | 0.0 | 0.0 |
RB |
9.204 |
OD2 |
RB |
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| ASP | D:926 | C:926 | 1.0 | 0.007 | H | -63.3 | -36.0 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:926 | A:926 | 0.0 | 0.0 | H | -65.7 | -35.8 | 0.0 | 0.0 | 0.0 |
HOH |
9.741 |
OD2 |
O |
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| ASP | D:926 | C:926 | 1.0 | 0.007 | H | -64.2 | -37.4 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:926 | A:926 | 0.0 | 0.0 | H | -64.7 | -40.9 | 0.0 | 0.0 | 0.0 | ||||||
| ASP | D:926 | C:926 | 1.0 | 0.007 | H | -64.8 | -41.8 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:926 | A:926 | 0.0 | 0.0 | H | -65.6 | -37.8 | 0.0 | 0.0 | 0.0 |
HOH |
9.998 |
OD2 |
O |
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| ASP | D:926 | C:926 | 1.0 | 0.007 | H | -65.5 | -37.2 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:926 | A:926 | 1.0 | 0.007 | H | -65.3 | -34.7 | 1.0 | 0.007 | 0.0 | ||||||
| ASP | D:926 | C:926 | 1.0 | 0.007 | H | -64.5 | -36.4 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:926 | A:926 | 0.0 | 0.0 | H | -63.8 | -38.2 | 0.0 | 0.0 | 0.0 | ||||||
| ASP | D:926 | C:926 | 1.0 | 0.007 | H | -63.8 | -38.3 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 98.13 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:926 | A:926 | 0.0 | 0.0 | H | -63.1 | -36.5 | 0.0 | 0.0 | 0.0 |
HOH |
9.929 |
OD2 |
O |
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| ASP | D:926 | C:926 | 1.0 | 0.007 | H | -62.6 | -36.6 | NA | NA | NA | |||||||||||||
| 4xe5 | 1 | Q08DA1 | 97.46 | 0.0 |
X-RAY |
2016-03-09 | ASP | A:931 | A:931 | 1.0 | 0.007 | H | -61.6 | -38.7 | 1.0 | 0.007 | 0.0 |
HOH |
9.093 |
OD2 |
O |
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| 3b8e | 1 | P05024 | 98.4 | 0.0 |
X-RAY |
2007-12-18 | ASP | A:908 | A:926 | 1.0 | 0.007 | H | -77.1 | -56.0 | 1.0 | 0.007 | 0.0 |
RB |
8.407 |
OD2 |
RB |
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| ASP | D:908 | C:926 | 3.0 | 0.02 | H | -73.9 | -56.3 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 98.4 | 0.0 |
X-RAY |
2010-02-16 | ASP | A:908 | A:926 | 1.0 | 0.007 | H | -75.2 | -60.4 | 1.0 | 0.007 | 0.0 |
RB |
8.295 |
OD2 |
RB |
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| ASP | D:908 | C:926 | 1.0 | 0.007 | H | -74.4 | -61.3 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 98.59 | 0.0 |
X-RAY |
2011-01-19 | ASP | A:902 | A:926 | 0.0 | 0.0 | H | -52.3 | -44.7 | 0.0 | 0.0 | 0.0 | ||||||
| ASP | D:902 | C:926 | 1.0 | 0.007 | H | -53.5 | -44.3 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2009-05-19 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.5 | -43.4 | 0.0 | 0.0 | 0.0 |
K HOH |
8.813 6.199 |
OD2 C |
K O |
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| 3a3y | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2009-09-08 | ASP | A:938 | A:933 | 2.0 | 0.013 | H | -51.1 | -38.1 | 2.0 | 0.013 | 0.0 |
K HOH |
8.595 6.088 |
OD2 C |
K O |
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| 5avq | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.5 | -43.5 | 0.0 | 0.0 | 0.0 |
K TL HOH |
8.812 8.812 8.617 |
OD2 OD2 OD2 |
K TL O |
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| 5avr | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.5 | -43.5 | 0.0 | 0.0 | 0.0 |
K TL HOH |
8.811 8.811 8.617 |
OD2 OD2 OD2 |
K TL O |
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| 5avs | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.5 | -43.5 | 0.0 | 0.0 | 0.0 |
K TL HOH |
8.812 8.812 8.617 |
OD2 OD2 OD2 |
K TL O |
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| 5avt | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.4 | -43.5 | 0.0 | 0.0 | 0.0 |
K TL HOH |
8.812 8.812 8.617 |
OD2 OD2 OD2 |
K TL O |
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| 5avu | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.5 | -43.5 | 0.0 | 0.0 | 0.0 |
K TL HOH |
8.812 8.812 8.617 |
OD2 OD2 OD2 |
K TL O |
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| 5avv | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.5 | -43.5 | 0.0 | 0.0 | 0.0 |
TL HOH |
8.813 8.617 |
OD2 OD2 |
TL O |
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| 5avw | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.5 | -43.4 | 0.0 | 0.0 | 0.0 |
TL HOH |
8.813 8.618 |
OD2 OD2 |
TL O |
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| 5avx | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.5 | -43.4 | 0.0 | 0.0 | 0.0 |
TL HOH |
8.812 8.617 |
OD2 OD2 |
TL O |
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| 5avy | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.5 | -43.5 | 0.0 | 0.0 | 0.0 |
TL HOH |
8.811 8.616 |
OD2 OD2 |
TL O |
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| 5avz | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.6 | -43.4 | 0.0 | 0.0 | 0.0 |
TL HOH |
8.813 8.617 |
OD2 OD2 |
TL O |
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| 5aw0 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.5 | -43.5 | 0.0 | 0.0 | 0.0 |
TL HOH |
8.813 8.617 |
OD2 OD2 |
TL O |
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| 5aw1 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.6 | -43.4 | 0.0 | 0.0 | 0.0 |
K TL HOH |
8.812 8.812 8.616 |
OD2 OD2 OD2 |
K TL O |
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| 5aw2 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.5 | -43.4 | 0.0 | 0.0 | 0.0 |
TL HOH |
8.813 8.617 |
OD2 OD2 |
TL O |
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| 5aw3 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.6 | -43.4 | 0.0 | 0.0 | 0.0 |
TL HOH |
8.813 8.618 |
OD2 OD2 |
TL O |
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| 5aw4 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.6 | -43.3 | 0.0 | 0.0 | 0.0 |
K RB HOH |
8.813 8.813 8.617 |
OD2 OD2 OD2 |
K RB O |
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| 5aw5 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.5 | -43.4 | 0.0 | 0.0 | 0.0 |
K RB HOH |
8.814 8.814 8.618 |
OD2 OD2 OD2 |
K RB O |
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| 5aw6 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.6 | -43.4 | 0.0 | 0.0 | 0.0 |
K RB HOH |
8.813 8.813 8.618 |
OD2 OD2 OD2 |
K RB O |
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| 5aw7 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.5 | -43.4 | 0.0 | 0.0 | 0.0 |
K RB HOH |
8.812 8.812 8.618 |
OD2 OD2 OD2 |
K RB O |
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| 5aw8 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -54.5 | -43.4 | 0.0 | 0.0 | 0.0 |
RB HOH |
8.814 8.618 |
OD2 OD2 |
RB O |
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| 5aw9 | 1 | Q4H132 | 87.84 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:938 | A:933 | 0.0 | 0.0 | H | -61.8 | -45.5 | 0.0 | 0.0 | 0.0 |
K HOH |
8.631 6.046 |
OD2 C |
K O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05023-f1 | 1 | P05023 | 100.0 | 0.0 | ASP | A:933 | A:933 | 1.0 | 0.007 | H | -58.8 | -47.5 | |
| af-p13637-f1 | 1 | P13637 | 87.88 | 0.0 | ASP | A:923 | A:923 | 1.0 | 0.007 | H | -59.1 | -45.5 | |
| af-p50993-f1 | 1 | P50993 | 86.71 | 0.0 | ASP | A:930 | A:930 | 1.0 | 0.007 | H | -59.1 | -44.8 | |