Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160091034 . T A CCDS1196.1:NM_000702.3:c.170cTg>cAg_NP_000693.1:p.57L>Q Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 LEU A:57 A:57 35.0 0.206 T -68.5 -48.3 35.0 0.206 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 LEU A:52 A:52 32.0 0.188 T -66.6 -0.1 32.0 0.188 0.0
LEU D:52 C:52 41.0 0.241 T -52.1 -25.6 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 LEU A:52 A:52 31.0 0.182 T -62.0 8.1 31.0 0.182 0.0 HOH
 9.982
 N
 O
LEU D:52 C:52 42.0 0.247 T -57.8 -16.9 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 LEU A:57 A:52 88.0 0.518 S -59.2 -38.6 88.0 0.518 0.0
LEU D:57 C:52 91.0 0.535 S -58.3 -38.1 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 LEU A:57 A:52 37.0 0.218 T -78.2 -34.7 37.0 0.218 0.0
LEU D:57 C:52 37.0 0.218 T -78.1 -35.0 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 LEU A:57 A:52 58.0 0.341 T -65.6 -54.7 58.0 0.341 0.0
LEU D:57 C:52 59.0 0.347 T -66.0 -54.5 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 LEU A:57 A:52 38.0 0.224 T -74.0 -41.8 38.0 0.224 0.0
LEU D:57 C:52 39.0 0.229 T -74.4 -41.5 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 LEU A:57 A:52 53.0 0.312 T -78.7 -34.5 53.0 0.312 0.0
LEU D:57 C:52 52.0 0.306 T -76.8 -36.6 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:52 A:52 53.0 0.312 T -77.3 -22.9 53.0 0.312 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:52 A:52 56.0 0.329 T -76.5 -17.2 56.0 0.329 0.0
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:52 A:52 51.0 0.3 T -71.3 -20.9 51.0 0.3 0.0
LEU C:52 C:52 48.0 0.282 T -70.5 -21.6 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:52 A:52 52.0 0.306 T -69.9 -21.3 52.0 0.306 0.0
LEU D:52 C:52 46.0 0.271 T -68.7 -21.8 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:52 A:52 59.0 0.347 T -80.7 -23.6 59.0 0.347 0.0
LEU D:52 C:52 46.0 0.271 T -77.9 -22.6 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:52 A:52 54.0 0.318 T -79.1 -13.3 54.0 0.318 0.0
LEU D:52 C:52 50.0 0.294 T -78.8 -15.5 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:52 A:52 57.0 0.335 T -80.5 -38.2 57.0 0.335 0.0
LEU D:52 C:52 50.0 0.294 T -80.6 -37.5 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:52 A:52 48.0 0.282 T -69.9 -21.1 48.0 0.282 0.0
LEU D:52 C:52 47.0 0.276 T -70.3 -21.4 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:52 A:52 50.0 0.294 T -76.0 -26.3 50.0 0.294 0.0
LEU D:52 C:52 51.0 0.3 T -73.3 -26.4 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:52 A:52 50.0 0.294 T -69.5 -21.0 50.0 0.294 0.0
LEU D:52 C:52 48.0 0.282 T -68.3 -21.1 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 LEU A:34 A:52 37.0 0.218 T -73.1 30.5 37.0 0.218 0.0
LEU D:34 C:52 36.0 0.212 T -71.8 30.5 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 LEU A:34 A:52 34.0 0.2 S 168.7 -49.8 34.0 0.2 0.0
LEU D:34 C:52 33.0 0.194 S 168.5 -50.4 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 LEU A:28 A:52 66.0 0.388 S -87.6 -27.4 66.0 0.388 0.0
LEU D:28 C:52 55.0 0.324 S -87.6 -26.4 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 LEU A:64 A:59 62.0 0.365 S -68.9 -21.4 62.0 0.365 0.0 HOH
 5.068
 N
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 LEU A:64 A:59 57.0 0.335 S -71.5 -28.6 57.0 0.335 0.0
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 62.0 0.365 S -68.9 -21.4 62.0 0.365 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 62.0 0.365 S -68.8 -21.4 62.0 0.365 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 62.0 0.365 S -68.9 -21.4 62.0 0.365 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 62.0 0.365 S -68.9 -21.4 62.0 0.365 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 62.0 0.365 S -69.0 -21.3 62.0 0.365 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 62.0 0.365 S -68.9 -21.4 62.0 0.365 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 62.0 0.365 S -69.0 -21.4 62.0 0.365 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 62.0 0.365 S -68.9 -21.3 62.0 0.365 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 62.0 0.365 S -68.9 -21.5 62.0 0.365 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 62.0 0.365 S -69.0 -21.3 62.0 0.365 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 62.0 0.365 S -68.9 -21.3 62.0 0.365 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 62.0 0.365 S -68.9 -21.3 62.0 0.365 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 62.0 0.365 S -69.0 -21.4 62.0 0.365 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 62.0 0.365 S -68.8 -21.5 62.0 0.365 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 62.0 0.365 S -68.9 -21.4 62.0 0.365 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 62.0 0.365 S -68.9 -21.4 62.0 0.365 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 61.0 0.359 S -68.9 -21.4 61.0 0.359 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 62.0 0.365 S -68.8 -21.4 62.0 0.365 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 62.0 0.365 S -68.9 -21.4 62.0 0.365 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:64 A:59 65.0 0.382 T -64.5 -24.5 65.0 0.382 0.0 HOH
 5.197
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 LEU A:57 A:57 53.0 0.312 T -63.1 -15.2
af-p13637-f1 1 P13637 88.37 0.0 CYS A:49 A:49 58.0 0.43 T -69.9 -13.4
af-p05023-f1 1 P05023 86.71 0.0 LEU A:59 A:59 57.0 0.335 T -65.1 -17.1
af-q13733-f1 1 Q13733 80.48 0.0 LEU A:67 A:67 45.0 0.265 T -64.5 -15.8