Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160093193 . C A CCDS1196.1:NM_000702.3:c.368cCa>cAa_NP_000693.1:p.123P>Q Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 PRO A:123 A:123 2.0 0.014 G -50.7 -12.2 2.0 0.014 0.0 OBN
 3.129
 CG
 O19
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 PRO A:118 A:118 21.0 0.145 -75.4 -151.6 21.0 0.145 0.0
PRO D:118 C:118 15.0 0.103 -75.0 -166.7 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 PRO A:118 A:118 21.0 0.145 -75.6 -154.5 21.0 0.145 0.0
PRO D:118 C:118 14.0 0.097 -73.2 -161.7 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 PRO A:123 A:118 108.0 0.745 -65.5 -24.8 108.0 0.745 0.0
PRO D:123 C:118 105.0 0.724 -64.7 -25.1 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 PRO A:123 A:118 0.0 0.0 G -49.7 -6.2 0.0 0.0 0.0 OBN
 3.285
 CG
 O19
PRO D:123 C:118 0.0 0.0 G -49.7 -6.3 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 PRO A:123 A:118 0.0 0.0 T -54.1 -9.1 0.0 0.0 0.0 BUF
 4.884
 CG
 C19
PRO D:123 C:118 0.0 0.0 T -53.8 -8.8 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 PRO A:123 A:118 1.0 0.007 G -50.6 -8.0 1.0 0.007 0.0 DGX
 4.774
 CG
 C19
PRO D:123 C:118 1.0 0.007 G -50.5 -7.9 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 PRO A:123 A:118 53.0 0.366 -58.4 153.9 53.0 0.366 0.0 JEO
 7.100
 CA
 OAW
PRO D:123 C:118 41.0 0.283 -58.9 157.8 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:118 A:118 49.0 0.338 -64.5 -172.7 49.0 0.338 0.0 PCW
 7.198
 O
 C8
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:118 A:118 55.0 0.379 -75.9 174.6 55.0 0.379 0.0 H0C
 7.447
 CA
 O1
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:118 A:118 53.0 0.366 -59.7 152.0 53.0 0.366 0.0 H0C
 5.793
 C
 O6
PRO C:118 C:118 48.0 0.331 -60.4 154.2 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:118 A:118 49.0 0.338 -56.9 153.1 49.0 0.338 0.0 BUF
 7.381
 C
 C19
PRO D:118 C:118 44.0 0.303 -53.6 164.1 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:118 A:118 50.0 0.345 -61.5 153.6 50.0 0.345 0.0
PRO D:118 C:118 53.0 0.366 -69.6 169.1 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:118 A:118 44.0 0.303 -59.6 144.8 44.0 0.303 0.0 DGX
 7.384
 C
 C19
PRO D:118 C:118 34.0 0.234 -57.6 148.9 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:118 A:118 52.0 0.359 -61.5 155.8 52.0 0.359 0.0 F9R
 7.475
 C
 C19
PRO D:118 C:118 43.0 0.297 -71.5 156.6 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:118 A:118 51.0 0.352 -58.5 153.5 51.0 0.352 0.0 PCW
OBN
 7.080
6.989
 O
C
 C8
O19
PRO D:118 C:118 46.0 0.317 -58.9 150.3 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:118 A:118 51.0 0.352 -61.0 152.2 51.0 0.352 0.0 E4R
 7.401
 C
 C19
PRO D:118 C:118 39.0 0.269 -61.9 155.5 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 PRO A:118 A:118 50.0 0.345 -57.3 153.9 50.0 0.345 0.0 BUF
 7.769
 C
 C19
PRO D:118 C:118 36.0 0.248 -55.4 156.9 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 PRO A:100 A:118 47.0 0.324 G -55.1 -2.5 47.0 0.324 0.0
PRO D:100 C:118 46.0 0.317 G -55.1 -2.6 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 PRO A:100 A:118 101.0 0.697 -62.3 40.2 101.0 0.697 0.0
PRO D:100 C:118 101.0 0.697 -45.3 -20.3 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 PRO A:94 A:118 39.0 0.269 -87.9 83.5 39.0 0.269 0.0 OBN
 2.766
 CG
 C19
PRO D:94 C:118 39.0 0.269 -87.7 86.8 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 PRO A:130 A:125 105.0 0.724 -76.0 2.1 105.0 0.724 0.0
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 PRO A:130 A:125 117.0 0.807 -67.8 99.1 117.0 0.807 0.0
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -76.0 2.1 105.0 0.724 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -76.0 2.1 104.0 0.717 0.007 B:C4IX13:0.007
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -76.0 2.0 105.0 0.724 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -76.1 2.2 105.0 0.724 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -76.0 2.0 105.0 0.724 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -76.0 2.1 104.0 0.717 0.007 B:C4IX13:0.007
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -76.0 2.1 104.0 0.717 0.007 B:C4IX13:0.007
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -75.9 2.0 105.0 0.724 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -76.0 2.1 105.0 0.724 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -76.0 2.1 105.0 0.724 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -75.9 2.0 105.0 0.724 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -76.0 2.1 105.0 0.724 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -76.0 2.0 105.0 0.724 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -75.9 2.1 105.0 0.724 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -75.9 2.0 104.0 0.717 0.007 B:C4IX13:0.007
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -76.1 2.1 105.0 0.724 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -76.0 2.0 105.0 0.724 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -76.0 2.0 104.0 0.717 0.007 B:C4IX13:0.007
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 105.0 0.724 -75.9 2.0 105.0 0.724 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 PRO A:130 A:125 112.0 0.772 -83.0 4.2 111.0 0.766 0.006 B:C4IX13:0.007

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 PRO A:123 A:123 33.0 0.228 -67.5 143.4
af-p13637-f1 1 P13637 88.37 0.0 PRO A:115 A:115 32.0 0.221 -67.7 138.6
af-p05023-f1 1 P05023 86.71 0.0 PRO A:125 A:125 33.0 0.228 -63.3 140.9
af-q13733-f1 1 Q13733 80.48 0.0 PRO A:133 A:133 37.0 0.255 -70.0 136.6