Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160093793 . C A CCDS1196.1:NM_000702.3:c.442Cag>Aag_NP_000693.1:p.148Q>K Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 GLN A:148 A:148 25.0 0.139 H -65.3 -52.5 25.0 0.139 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 GLN A:143 A:143 12.0 0.067 H -61.5 -55.7 12.0 0.067 0.0 PC1
 3.719
 OE1
 O11
GLN D:143 C:143 5.0 0.028 H -71.5 -27.6 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 GLN A:143 A:143 11.0 0.061 H -62.6 -62.8 11.0 0.061 0.0 PC1
EFO
 3.967
9.599
 OE1
C
 O11
C1D
GLN D:143 C:143 7.0 0.039 H -74.9 -25.8 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 GLN A:148 A:143 4.0 0.022 H -68.0 -29.5 4.0 0.022 0.0
GLN D:148 C:143 4.0 0.022 H -68.6 -29.7 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 GLN A:148 A:143 22.0 0.122 H -62.2 -56.0 22.0 0.122 0.0
GLN D:148 C:143 20.0 0.111 H -61.6 -57.1 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 GLN A:148 A:143 28.0 0.156 H -68.7 -46.0 28.0 0.156 0.0
GLN D:148 C:143 28.0 0.156 H -68.0 -46.2 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 GLN A:148 A:143 22.0 0.122 H -64.5 -54.6 22.0 0.122 0.0
GLN D:148 C:143 20.0 0.111 H -64.6 -54.7 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 GLN A:148 A:143 23.0 0.128 H -73.4 -44.4 23.0 0.128 0.0 PCW
 2.849
 NE2
 O1P
GLN D:148 C:143 23.0 0.128 H -73.5 -43.0 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:143 A:143 28.0 0.156 H -64.1 -50.1 28.0 0.156 0.0 PCW
PCW
PCW
 3.605
9.766
4.619
 NE2
NE2
NE2
 O1P
O1P
O1P
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:143 A:143 28.0 0.156 H -64.8 -48.3 28.0 0.156 0.0 PCW
PCW
 3.349
7.534
 NE2
NE2
 O1P
O1P
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:143 A:143 21.0 0.117 H -71.8 -48.5 21.0 0.117 0.0 PCW
PCW
 3.875
8.408
 NE2
NE2
 O1P
C7
GLN C:143 C:143 23.0 0.128 H -71.6 -48.8 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:143 A:143 23.0 0.128 H -71.1 -50.7 23.0 0.128 0.0 PCW
PCW
PCW
 2.743
7.598
7.319
 NE2
NE2
N
 O1P
O1P
O4P
GLN D:143 C:143 25.0 0.139 H -69.6 -49.1 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:143 A:143 25.0 0.139 H -72.0 -47.5 25.0 0.139 0.0 PCW
PCW
 4.051
9.620
 NE2
O
 O1P
O2P
GLN D:143 C:143 28.0 0.156 H -71.2 -48.0 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:143 A:143 20.0 0.111 H -71.4 -55.0 20.0 0.111 0.0 PCW
PCW
 2.431
7.897
 NE2
O
 O1P
C5
GLN D:143 C:143 21.0 0.117 H -71.5 -53.5 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:143 A:143 24.0 0.133 H -67.2 -52.2 24.0 0.133 0.0 PCW
PCW
 3.506
7.175
 NE2
N
 O1P
O2P
GLN D:143 C:143 24.0 0.133 H -67.4 -51.6 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:143 A:143 22.0 0.122 H -71.1 -49.3 22.0 0.122 0.0 PCW
PCW
 4.237
6.665
 NE2
N
 O31
C5
GLN D:143 C:143 29.0 0.161 H -70.5 -50.1 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:143 A:143 22.0 0.122 H -69.3 -50.7 22.0 0.122 0.0 PCW
PCW
 2.427
8.029
 NE2
N
 O1P
O4P
GLN D:143 C:143 22.0 0.122 H -70.1 -49.5 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:143 A:143 22.0 0.122 H -70.5 -50.0 22.0 0.122 0.0 PCW
PCW
 2.877
7.432
 NE2
N
 O1P
O4P
GLN D:143 C:143 26.0 0.144 H -70.0 -48.7 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 GLN A:125 A:143 24.0 0.133 T -87.8 -15.8 24.0 0.133 0.0
GLN D:125 C:143 21.0 0.117 T -88.0 -15.5 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 GLN A:125 A:143 10.0 0.056 S -131.9 -66.8 10.0 0.056 0.0
GLN D:125 C:143 10.0 0.056 G -72.4 -36.1 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 GLN A:119 A:143 32.0 0.178 H -69.6 -63.6 32.0 0.178 0.0
GLN D:119 C:143 34.0 0.189 H -70.6 -63.2 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 GLN A:155 A:150 14.0 0.078 H -77.5 -34.9 14.0 0.078 0.0 HOH
 2.722
 OE1
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 GLN A:155 A:150 14.0 0.078 H -79.0 -30.0 14.0 0.078 0.0 HOH
 2.622
 OE1
 O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 14.0 0.078 H -77.6 -34.9 14.0 0.078 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 15.0 0.083 H -77.6 -34.9 15.0 0.083 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 15.0 0.083 H -77.6 -34.9 15.0 0.083 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 15.0 0.083 H -77.5 -34.9 15.0 0.083 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 14.0 0.078 H -77.6 -34.9 14.0 0.078 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 15.0 0.083 H -77.6 -34.9 15.0 0.083 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 14.0 0.078 H -77.5 -35.0 14.0 0.078 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 15.0 0.083 H -77.6 -34.9 15.0 0.083 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 15.0 0.083 H -77.4 -35.0 15.0 0.083 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 15.0 0.083 H -77.5 -34.9 15.0 0.083 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 15.0 0.083 H -77.5 -35.0 15.0 0.083 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 15.0 0.083 H -77.6 -34.9 15.0 0.083 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 15.0 0.083 H -77.5 -34.9 15.0 0.083 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 15.0 0.083 H -77.6 -34.9 15.0 0.083 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 14.0 0.078 H -77.5 -34.9 14.0 0.078 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 15.0 0.083 H -77.7 -34.9 15.0 0.083 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 14.0 0.078 H -77.6 -34.9 14.0 0.078 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 14.0 0.078 H -77.5 -35.0 14.0 0.078 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 14.0 0.078 H -77.5 -34.9 14.0 0.078 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:155 A:150 12.0 0.067 H -75.8 -32.3 12.0 0.067 0.0 HOH
 2.777
 OE1
 O
1bg5 1 P08515 96.0 2e-06 X-RAY
 1999-01-13 GLN A:230 A:230 120.0 0.667 T 164.5 83.0 120.0 0.667 0.0 HOH
 2.461
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 GLN A:148 A:148 19.0 0.106 H -65.0 -42.5
af-p13637-f1 1 P13637 88.37 0.0 GLN A:140 A:140 36.0 0.2 H -71.8 -43.3
af-p05023-f1 1 P05023 86.71 0.0 GLN A:150 A:150 33.0 0.183 H -70.7 -44.7
af-q13733-f1 1 Q13733 80.48 0.0 GLN A:158 A:158 27.0 0.15 H -62.2 -45.0