Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160094115 . G A CCDS1196.1:NM_000702.3:c.525aaG>aaA_NP_000693.1:p.175K>K Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 LYS A:175 A:175 109.0 0.545 E -78.0 120.9 109.0 0.545 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 LYS A:170 A:170 28.0 0.14 -125.4 138.3 28.0 0.14 0.0 HOH
 9.403
 C
 O
LYS D:170 C:170 23.0 0.115 E -112.1 155.5 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 LYS A:170 A:170 28.0 0.14 -122.0 141.3 28.0 0.14 0.0 HOH
 9.965
 C
 O
LYS D:170 C:170 20.0 0.1 -121.9 152.0 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 LYS A:175 A:170 18.0 0.09 E -91.9 145.9 18.0 0.09 0.0
LYS D:175 C:170 18.0 0.09 E -91.9 145.7 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 LYS A:175 A:170 128.0 0.64 E -76.2 121.7 128.0 0.64 0.0
LYS D:175 C:170 131.0 0.655 E -76.8 122.2 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 LYS A:175 A:170 110.0 0.55 E -61.9 124.8 110.0 0.55 0.0
LYS D:175 C:170 111.0 0.555 E -62.3 124.8 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 LYS A:175 A:170 119.0 0.595 E -75.8 123.7 119.0 0.595 0.0
LYS D:175 C:170 120.0 0.6 E -76.0 123.6 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 LYS A:175 A:170 117.0 0.585 E -84.2 138.5 117.0 0.585 0.0
LYS D:175 C:170 122.0 0.61 E -84.5 136.3 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:170 A:170 131.0 0.655 E -79.0 138.8 131.0 0.655 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:170 A:170 126.0 0.63 E -76.3 136.7 126.0 0.63 0.0
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:170 A:170 131.0 0.655 E -89.0 126.8 131.0 0.655 0.0
LYS C:170 C:170 128.0 0.64 E -88.7 125.3 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:170 A:170 133.0 0.665 E -87.8 127.3 133.0 0.665 0.0
LYS D:170 C:170 126.0 0.63 E -88.0 125.6 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:170 A:170 125.0 0.625 E -83.8 130.6 125.0 0.625 0.0
LYS D:170 C:170 122.0 0.61 E -82.3 124.8 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:170 A:170 130.0 0.65 E -81.0 134.2 130.0 0.65 0.0
LYS D:170 C:170 126.0 0.63 E -80.4 133.1 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:170 A:170 120.0 0.6 E -83.7 137.4 120.0 0.6 0.0
LYS D:170 C:170 122.0 0.61 E -82.4 137.5 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:170 A:170 131.0 0.655 E -88.7 126.8 131.0 0.655 0.0
LYS D:170 C:170 127.0 0.635 E -88.7 125.7 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:170 A:170 120.0 0.6 E -86.2 115.8 120.0 0.6 0.0
LYS D:170 C:170 122.0 0.61 E -86.9 114.3 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:170 A:170 132.0 0.66 E -88.3 126.6 132.0 0.66 0.0
LYS D:170 C:170 126.0 0.63 E -88.1 126.5 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 LYS A:152 A:170 116.0 0.58 E -102.2 126.5 116.0 0.58 0.0
LYS D:152 C:170 114.0 0.57 E -102.4 126.4 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 LYS A:152 A:170 112.0 0.56 E -99.7 132.6 112.0 0.56 0.0
LYS D:152 C:170 111.0 0.555 E -98.4 133.9 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 LYS A:146 A:170 107.0 0.535 E -94.7 135.0 107.0 0.535 0.0
LYS D:146 C:170 107.0 0.535 E -95.1 135.2 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 LYS A:182 A:177 96.0 0.48 E -88.9 132.0 96.0 0.48 0.0 HOH
 7.733
 NZ
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 LYS A:182 A:177 90.0 0.45 E -90.8 142.9 90.0 0.45 0.0 HOH
 7.968
 CD
 O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 96.0 0.48 E -88.8 132.0 96.0 0.48 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 96.0 0.48 E -88.9 132.1 96.0 0.48 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 96.0 0.48 E -89.0 132.1 96.0 0.48 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 96.0 0.48 E -88.9 132.0 96.0 0.48 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 96.0 0.48 E -88.9 132.1 96.0 0.48 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 95.0 0.475 E -88.8 132.0 95.0 0.475 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 96.0 0.48 E -88.8 132.0 96.0 0.48 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 94.0 0.47 E -88.9 132.0 94.0 0.47 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 95.0 0.475 E -88.9 132.1 95.0 0.475 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 96.0 0.48 E -88.9 132.0 96.0 0.48 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 96.0 0.48 E -88.8 132.0 96.0 0.48 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 95.0 0.475 E -88.9 132.0 95.0 0.475 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 96.0 0.48 E -88.8 132.1 96.0 0.48 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 96.0 0.48 E -88.9 132.0 96.0 0.48 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 96.0 0.48 E -88.9 132.0 96.0 0.48 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 96.0 0.48 E -88.9 132.0 96.0 0.48 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 96.0 0.48 E -88.9 132.1 96.0 0.48 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 96.0 0.48 E -88.9 132.0 96.0 0.48 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 96.0 0.48 E -88.9 132.0 96.0 0.48 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:182 A:177 98.0 0.49 E -87.9 132.7 98.0 0.49 0.0 HOH
 7.753
 NZ
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 LYS A:175 A:175 111.0 0.555 E -80.2 118.8
af-p13637-f1 1 P13637 88.37 0.0 LYS A:167 A:167 107.0 0.535 E -80.1 119.6
af-p05023-f1 1 P05023 86.71 0.0 LYS A:177 A:177 110.0 0.55 E -79.8 123.1
af-q13733-f1 1 Q13733 80.48 0.0 LYS A:185 A:185 106.0 0.53 E -80.6 121.9