Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160094161 . G A CCDS1196.1:NM_000702.3:c.571Gtg>Atg_NP_000693.1:p.191V>M Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 VAL A:191 A:191 5.0 0.032 E -120.8 146.8 5.0 0.032 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 VAL A:186 A:186 3.0 0.019 E -96.3 149.1 3.0 0.019 0.0
VAL D:186 C:186 7.0 0.045 E -88.2 144.7 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 VAL A:186 A:186 7.0 0.045 E -102.8 141.0 7.0 0.045 0.0
VAL D:186 C:186 7.0 0.045 E -104.3 153.6 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 VAL A:191 A:186 6.0 0.039 -149.3 77.5 6.0 0.039 0.0
VAL D:191 C:186 5.0 0.032 -148.7 78.2 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 VAL A:191 A:186 3.0 0.019 E -119.0 148.0 3.0 0.019 0.0
VAL D:191 C:186 4.0 0.026 E -119.0 147.7 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 VAL A:191 A:186 5.0 0.032 E -118.2 141.8 5.0 0.032 0.0
VAL D:191 C:186 6.0 0.039 E -118.3 142.4 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 VAL A:191 A:186 3.0 0.019 E -117.9 144.6 3.0 0.019 0.0
VAL D:191 C:186 3.0 0.019 E -117.6 144.5 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 VAL A:191 A:186 4.0 0.026 E -133.5 136.7 4.0 0.026 0.0
VAL D:191 C:186 4.0 0.026 E -131.5 134.7 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:186 A:186 4.0 0.026 E -104.5 123.9 4.0 0.026 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:186 A:186 3.0 0.019 E -105.1 120.6 3.0 0.019 0.0
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:186 A:186 3.0 0.019 E -130.2 143.5 3.0 0.019 0.0
VAL C:186 C:186 7.0 0.045 E -128.0 142.6 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:186 A:186 3.0 0.019 E -129.9 142.7 3.0 0.019 0.0
VAL D:186 C:186 5.0 0.032 E -127.8 141.7 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:186 A:186 4.0 0.026 E -124.7 144.2 4.0 0.026 0.0
VAL D:186 C:186 6.0 0.039 E -124.4 144.3 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:186 A:186 6.0 0.039 E -128.3 146.9 6.0 0.039 0.0
VAL D:186 C:186 6.0 0.039 E -126.6 147.2 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:186 A:186 4.0 0.026 E -130.5 138.1 4.0 0.026 0.0
VAL D:186 C:186 5.0 0.032 E -129.7 137.5 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:186 A:186 4.0 0.026 E -130.2 143.5 4.0 0.026 0.0
VAL D:186 C:186 5.0 0.032 E -127.7 143.0 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:186 A:186 4.0 0.026 E -129.4 139.5 4.0 0.026 0.0
VAL D:186 C:186 5.0 0.032 E -127.3 142.1 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:186 A:186 3.0 0.019 E -128.3 141.4 3.0 0.019 0.0
VAL D:186 C:186 3.0 0.019 E -126.7 139.6 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 VAL A:168 A:186 8.0 0.052 E -129.4 124.1 8.0 0.052 0.0
VAL D:168 C:186 8.0 0.052 E -130.4 125.1 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 VAL A:168 A:186 6.0 0.039 -84.0 134.6 6.0 0.039 0.0
VAL D:168 C:186 7.0 0.045 -80.5 135.9 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 VAL A:162 A:186 9.0 0.058 E -107.2 153.4 9.0 0.058 0.0
VAL D:162 C:186 9.0 0.058 E -106.7 154.1 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 VAL A:198 A:193 5.0 0.032 E -130.3 157.0 5.0 0.032 0.0 HOH
 3.541
 CA
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 VAL A:198 A:193 4.0 0.026 E -127.7 145.7 4.0 0.026 0.0 HOH
 3.407
 CA
 O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.4 157.0 5.0 0.032 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.3 157.0 5.0 0.032 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.3 157.0 5.0 0.032 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.3 157.0 5.0 0.032 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.2 157.0 5.0 0.032 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.3 157.1 5.0 0.032 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.3 157.0 5.0 0.032 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.3 157.0 5.0 0.032 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.3 157.0 5.0 0.032 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.3 157.0 5.0 0.032 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.3 157.0 5.0 0.032 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.3 157.0 5.0 0.032 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.2 157.1 5.0 0.032 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.3 157.0 5.0 0.032 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.4 157.1 5.0 0.032 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.3 157.0 5.0 0.032 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.4 157.0 5.0 0.032 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.3 157.0 5.0 0.032 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -130.3 157.1 5.0 0.032 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:198 A:193 5.0 0.032 E -128.6 152.2 5.0 0.032 0.0 HOH
 3.636
 CA
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 VAL A:191 A:191 2.0 0.013 E -117.4 140.0
af-p13637-f1 1 P13637 88.37 0.0 ILE A:183 A:183 3.0 0.017 E -116.3 143.1
af-p05023-f1 1 P05023 86.71 0.0 VAL A:193 A:193 4.0 0.026 E -124.0 142.7
af-q13733-f1 1 Q13733 80.48 0.0 ILE A:201 A:201 3.0 0.017 E -118.5 144.2