Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 160097429 | . | G | A | CCDS1196.1:NM_000702.3:c.836cGg>cAg_NP_000693.1:p.279R>Q | Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
4xe5 | 1 | Q08DA1 | 86.79 | 0.0 |
X-RAY |
2016-03-09 | GLN | A:279 | A:279 | 122.0 | 0.678 | -72.1 | 133.8 | 122.0 | 0.678 | 0.0 |
MG |
8.038 |
N |
MG |
|||
3wgu | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | GLN | A:274 | A:274 | 104.0 | 0.578 | -133.4 | 98.2 | 104.0 | 0.578 | 0.0 |
NA HOH |
9.218 5.533 |
N OE1 |
NA O |
|||
GLN | D:274 | C:274 | 118.0 | 0.656 | -103.4 | 112.3 | NA | NA | NA | ||||||||||||||
3wgv | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | GLN | A:274 | A:274 | 105.0 | 0.583 | -134.9 | 97.9 | 105.0 | 0.583 | 0.0 |
NA EFO HOH |
9.049 3.806 6.159 |
N OE1 O |
NA C51 O |
|||
GLN | D:274 | C:274 | 118.0 | 0.656 | -109.6 | 102.5 | NA | NA | NA | ||||||||||||||
4hqj | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-10-02 | GLN | A:279 | A:274 | 187.0 | 1.0 | -122.1 | 152.9 | 187.0 | 1.0 | 0.0 | |||||||
GLN | D:279 | C:274 | 180.0 | 1.0 | -122.6 | 152.4 | NA | NA | NA | ||||||||||||||
4hyt | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-06-26 | GLN | A:279 | A:274 | 109.0 | 0.606 | -74.4 | 123.6 | 109.0 | 0.606 | 0.0 |
MG 17F |
8.420 9.726 |
N OE1 |
MG O5 |
|||
GLN | D:279 | C:274 | 110.0 | 0.611 | -73.4 | 123.7 | NA | NA | NA | ||||||||||||||
4res | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | GLN | A:279 | A:274 | 94.0 | 0.522 | -99.3 | 126.6 | 94.0 | 0.522 | 0.0 |
K |
8.849 |
N |
K |
|||
GLN | D:279 | C:274 | 98.0 | 0.544 | -98.7 | 127.2 | NA | NA | NA | ||||||||||||||
4ret | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | GLN | A:279 | A:274 | 110.0 | 0.611 | -78.5 | 125.1 | 110.0 | 0.611 | 0.0 |
MG |
8.214 |
N |
MG |
|||
GLN | D:279 | C:274 | 114.0 | 0.633 | -77.6 | 125.1 | NA | NA | NA | ||||||||||||||
7evx | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2021-07-07 | GLN | A:279 | A:274 | 116.0 | 0.644 | -110.0 | 118.6 | 116.0 | 0.644 | 0.0 |
NA PCW |
7.905 7.257 |
N OE1 |
NA C6 |
|||
GLN | D:279 | C:274 | 110.0 | 0.611 | -112.0 | 118.7 | NA | NA | NA | ||||||||||||||
7d91 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLN | A:274 | A:274 | 121.0 | 0.672 | -94.6 | 122.0 | 121.0 | 0.672 | 0.0 |
MG HOH |
8.239 8.579 |
N N |
MG O |
|||
7d92 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLN | A:274 | A:274 | 119.0 | 0.661 | -98.6 | 118.6 | 119.0 | 0.661 | 0.0 |
MG HOH |
8.267 8.896 |
N N |
MG O |
|||
7d93 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLN | A:274 | A:274 | 106.0 | 0.589 | -122.6 | 115.7 | 106.0 | 0.589 | 0.0 |
NA |
7.422 |
N |
NA |
|||
GLN | C:274 | C:274 | 110.0 | 0.611 | -123.5 | 116.5 | NA | NA | NA | ||||||||||||||
7d94 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLN | A:274 | A:274 | 101.0 | 0.561 | -120.5 | 115.6 | 101.0 | 0.561 | 0.0 |
NA |
7.596 |
N |
NA |
|||
GLN | D:274 | C:274 | 105.0 | 0.583 | -122.9 | 115.9 | NA | NA | NA | ||||||||||||||
7ddf | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLN | A:274 | A:274 | 113.0 | 0.628 | -105.1 | 119.5 | 113.0 | 0.628 | 0.0 |
NA |
7.471 |
N |
NA |
|||
GLN | D:274 | C:274 | 116.0 | 0.644 | -105.4 | 120.3 | NA | NA | NA | ||||||||||||||
7ddh | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLN | A:274 | A:274 | 109.0 | 0.606 | -128.3 | 118.2 | 109.0 | 0.606 | 0.0 |
NA PCW |
7.610 7.979 |
N OE1 |
NA C6 |
|||
GLN | D:274 | C:274 | 112.0 | 0.622 | -129.7 | 118.1 | NA | NA | NA | ||||||||||||||
7ddi | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLN | A:274 | A:274 | 106.0 | 0.589 | -110.9 | 121.4 | 106.0 | 0.589 | 0.0 |
NA PCW |
7.558 6.312 |
N OE1 |
NA C6 |
|||
GLN | D:274 | C:274 | 110.0 | 0.611 | -112.6 | 121.1 | NA | NA | NA | ||||||||||||||
7ddj | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLN | A:274 | A:274 | 106.0 | 0.589 | -123.1 | 115.2 | 106.0 | 0.589 | 0.0 |
NA PCW |
7.201 9.291 |
N OE1 |
NA C6 |
|||
GLN | D:274 | C:274 | 112.0 | 0.622 | -124.4 | 116.3 | NA | NA | NA | ||||||||||||||
7ddk | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLN | A:274 | A:274 | 109.0 | 0.606 | -115.2 | 121.0 | 109.0 | 0.606 | 0.0 |
NA |
7.904 |
N |
NA |
|||
GLN | D:274 | C:274 | 115.0 | 0.639 | -116.8 | 119.6 | NA | NA | NA | ||||||||||||||
7ddl | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLN | A:274 | A:274 | 102.0 | 0.567 | -121.6 | 116.1 | 102.0 | 0.567 | 0.0 |
NA PCW |
7.446 7.568 |
N OE1 |
NA C6 |
|||
GLN | D:274 | C:274 | 106.0 | 0.589 | -123.3 | 115.6 | NA | NA | NA | ||||||||||||||
3b8e | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2007-12-18 | GLN | A:256 | A:274 | 142.0 | 0.789 | -90.8 | 118.9 | 142.0 | 0.789 | 0.0 |
RB |
8.228 |
N |
RB |
|||
GLN | D:256 | C:274 | 135.0 | 0.75 | -90.7 | 121.1 | NA | NA | NA | ||||||||||||||
3kdp | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2010-02-16 | GLN | A:256 | A:274 | 106.0 | 0.589 | -52.9 | 127.8 | 106.0 | 0.589 | 0.0 |
RB |
8.112 |
O |
RB |
|||
GLN | D:256 | C:274 | 118.0 | 0.656 | -50.3 | 126.6 | NA | NA | NA | ||||||||||||||
3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | GLN | A:250 | A:274 | 156.0 | 0.867 | -92.0 | 131.7 | 156.0 | 0.867 | 0.0 | |||||||
GLN | D:250 | C:274 | 157.0 | 0.872 | -91.3 | 132.1 | NA | NA | NA | ||||||||||||||
2zxe | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-05-19 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.6 | 138.9 | 161.0 | 0.716 | 0.0 |
K HOH |
9.107 3.451 |
O CA |
K O |
|||
3a3y | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-09-08 | ARG | A:286 | A:281 | 149.0 | 0.662 | -80.2 | 132.2 | 149.0 | 0.662 | 0.0 |
K |
8.403 |
O |
K |
|||
5avq | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.7 | 139.0 | 161.0 | 0.716 | 0.0 |
K TL |
9.107 9.107 |
O O |
K TL |
|||
5avr | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.5 | 138.9 | 161.0 | 0.716 | 0.0 |
K TL |
9.108 9.108 |
O O |
K TL |
|||
5avs | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.6 | 138.9 | 161.0 | 0.716 | 0.0 |
K TL |
9.108 9.108 |
O O |
K TL |
|||
5avt | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.5 | 138.9 | 161.0 | 0.716 | 0.0 |
K TL |
9.107 9.107 |
O O |
K TL |
|||
5avu | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.5 | 138.9 | 161.0 | 0.716 | 0.0 |
K TL |
9.108 9.108 |
O O |
K TL |
|||
5avv | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.7 | 138.9 | 161.0 | 0.716 | 0.0 |
K TL |
9.107 9.107 |
O O |
K TL |
|||
5avw | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.6 | 138.8 | 161.0 | 0.716 | 0.0 |
K TL |
9.107 9.107 |
O O |
K TL |
|||
5avx | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.6 | 138.9 | 161.0 | 0.716 | 0.0 |
K TL |
9.106 9.106 |
O O |
K TL |
|||
5avy | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.5 | 138.9 | 161.0 | 0.716 | 0.0 |
K TL |
9.108 9.108 |
O O |
K TL |
|||
5avz | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.5 | 138.9 | 161.0 | 0.716 | 0.0 |
K TL |
9.108 9.108 |
O O |
K TL |
|||
5aw0 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.4 | 138.9 | 161.0 | 0.716 | 0.0 |
K TL |
9.108 9.108 |
O O |
K TL |
|||
5aw1 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.6 | 139.0 | 161.0 | 0.716 | 0.0 |
K TL |
9.107 9.107 |
O O |
K TL |
|||
5aw2 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.6 | 138.9 | 161.0 | 0.716 | 0.0 |
K TL |
9.108 9.108 |
O O |
K TL |
|||
5aw3 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.5 | 138.9 | 161.0 | 0.716 | 0.0 |
K TL |
9.107 9.107 |
O O |
K TL |
|||
5aw4 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 160.0 | 0.711 | -82.5 | 138.9 | 160.0 | 0.711 | 0.0 |
K RB |
9.108 9.108 |
O O |
K RB |
|||
5aw5 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.5 | 138.9 | 161.0 | 0.716 | 0.0 |
K RB |
9.107 9.107 |
O O |
K RB |
|||
5aw6 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.6 | 138.9 | 161.0 | 0.716 | 0.0 |
K RB |
9.109 9.109 |
O O |
K RB |
|||
5aw7 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.7 | 138.9 | 161.0 | 0.716 | 0.0 |
K RB |
9.109 9.109 |
O O |
K RB |
|||
5aw8 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 161.0 | 0.716 | -82.5 | 138.9 | 161.0 | 0.716 | 0.0 |
RB |
9.107 |
O |
RB |
|||
5aw9 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:286 | A:281 | 158.0 | 0.702 | -82.7 | 137.9 | 158.0 | 0.702 | 0.0 |
K HOH |
9.299 3.585 |
O CA |
K O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p50993-f1 | 1 | P50993 | 100.0 | 0.0 | ARG | A:279 | A:279 | 159.0 | 0.707 | -72.6 | 130.6 | ||
af-p13637-f1 | 1 | P13637 | 88.37 | 0.0 | LYS | A:271 | A:271 | 122.0 | 0.61 | -71.1 | 132.7 | ||
af-p05023-f1 | 1 | P05023 | 86.71 | 0.0 | GLN | A:281 | A:281 | 123.0 | 0.683 | -87.4 | 134.8 | ||
af-q13733-f1 | 1 | Q13733 | 80.48 | 0.0 | GLN | A:289 | A:289 | 127.0 | 0.706 | -74.0 | 131.6 |