Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160097466 . G A CCDS1196.1:NM_000702.3:c.873caG>caA_NP_000693.1:p.291Q>Q Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 HIS A:291 A:291 117.0 0.6 H -57.5 -39.7 117.0 0.6 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 HIS A:286 A:286 126.0 0.646 H -62.6 -35.0 126.0 0.646 0.0 PC1
PC1
HOH
 7.823
7.976
7.938
 N
C
NE2
 O32
O32
O
HIS D:286 C:286 114.0 0.585 H -59.6 -70.6 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 HIS A:286 A:286 128.0 0.656 H -61.3 -46.0 128.0 0.656 0.0 PC1
PC1
EFO
 7.890
8.118
4.568
 N
C
CD2
 O32
O32
C3B
HIS D:286 C:286 113.0 0.579 H -64.6 -69.1 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 HIS A:291 A:286 130.0 0.667 H -63.8 -44.2 130.0 0.667 0.0
HIS D:291 C:286 128.0 0.656 H -62.4 -44.9 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 HIS A:291 A:286 110.0 0.564 H -54.6 -43.0 110.0 0.564 0.0 17F
17F
 6.804
3.259
 O
ND1
 O1
O5
HIS D:291 C:286 109.0 0.559 H -54.4 -42.7 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 HIS A:291 A:286 114.0 0.585 H -71.5 -25.9 114.0 0.585 0.0
HIS D:291 C:286 115.0 0.59 H -71.7 -25.2 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 HIS A:291 A:286 112.0 0.574 H -56.6 -43.4 112.0 0.574 0.0 17F
17F
 4.414
2.655
 O
ND1
 O9
O5
HIS D:291 C:286 113.0 0.579 H -56.3 -43.4 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 HIS A:291 A:286 111.0 0.569 H -58.2 -27.7 111.0 0.569 0.0 PCW
PCW
 4.648
2.705
 O
ND1
 O11
O2P
HIS D:291 C:286 110.0 0.564 H -60.9 -34.9 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 HIS A:286 A:286 111.0 0.569 H -61.8 -46.8 106.0 0.544 0.025 B:P05027:0.026
 PCW
PCW
 5.414
2.919
 O
CB
 O11
O2P
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 HIS A:286 A:286 114.0 0.585 H -61.6 -43.5 112.0 0.574 0.011 B:P05027:0.01
 PCW
 6.629
 O
 O11
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 HIS A:286 A:286 134.0 0.687 H -58.8 -42.3 134.0 0.687 0.0 PCW
 7.429
 O
 O11
HIS C:286 C:286 133.0 0.682 H -58.8 -42.0 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 HIS A:286 A:286 116.0 0.595 H -59.5 -42.2 116.0 0.595 0.0 PCW
 5.495
 O
 O11
HIS D:286 C:286 113.0 0.579 H -60.4 -40.6 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 HIS A:286 A:286 111.0 0.569 H -59.8 -40.5 107.0 0.549 0.02 B:P05027:0.021
 PCW
 5.270
 O
 O11
HIS D:286 C:286 109.0 0.559 H -63.9 -38.9 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 HIS A:286 A:286 109.0 0.559 H -60.1 -46.5 109.0 0.559 0.0 PCW
PCW
 5.270
2.740
 O
ND1
 O11
O2P
HIS D:286 C:286 117.0 0.6 H -60.6 -45.9 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 HIS A:286 A:286 110.0 0.564 H -59.5 -46.0 110.0 0.564 0.0 PCW
PCW
 5.223
2.848
 O
ND1
 O11
O2P
HIS D:286 C:286 108.0 0.554 H -59.2 -45.6 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 HIS A:286 A:286 111.0 0.569 H -59.7 -42.8 111.0 0.569 0.0 PCW
PCW
 6.943
3.591
 O
O
 O31
O3
HIS D:286 C:286 111.0 0.569 H -61.5 -41.2 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 HIS A:286 A:286 108.0 0.554 H -57.9 -46.8 108.0 0.554 0.0 PCW
 5.264
 O
 O11
HIS D:286 C:286 107.0 0.549 H -59.6 -44.3 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 HIS A:286 A:286 114.0 0.585 H -61.2 -44.5 114.0 0.585 0.0 PCW
PCW
 5.379
3.359
 O
ND1
 O11
O2P
HIS D:286 C:286 115.0 0.59 H -61.5 -42.1 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 HIS A:268 A:286 111.0 0.569 H -80.4 -55.1 111.0 0.569 0.0
HIS D:268 C:286 106.0 0.544 H -73.0 -57.7 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 HIS A:268 A:286 129.0 0.662 H -60.7 -34.0 129.0 0.662 0.0
HIS D:268 C:286 125.0 0.641 H -57.1 -63.9 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 HIS A:262 A:286 119.0 0.61 H -46.0 -36.8 119.0 0.61 0.0
HIS D:262 C:286 117.0 0.6 H -46.4 -37.2 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 HIS A:298 A:293 132.0 0.677 H -58.4 -46.2 132.0 0.677 0.0 HOH
 2.706
 ND1
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 HIS A:298 A:293 109.0 0.559 H -68.1 -48.0 109.0 0.559 0.0 HOH
 8.187
 N
 O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 132.0 0.677 H -58.3 -46.1 132.0 0.677 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 132.0 0.677 H -58.4 -46.2 132.0 0.677 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 132.0 0.677 H -58.4 -46.2 132.0 0.677 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 132.0 0.677 H -58.5 -46.1 132.0 0.677 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 132.0 0.677 H -58.4 -46.1 132.0 0.677 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 132.0 0.677 H -58.4 -46.1 132.0 0.677 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 132.0 0.677 H -58.3 -46.2 132.0 0.677 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 132.0 0.677 H -58.3 -46.1 132.0 0.677 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 132.0 0.677 H -58.3 -46.3 132.0 0.677 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 132.0 0.677 H -58.3 -46.2 132.0 0.677 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 131.0 0.672 H -58.4 -46.2 131.0 0.672 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 132.0 0.677 H -58.4 -46.2 132.0 0.677 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 132.0 0.677 H -58.3 -46.2 132.0 0.677 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 132.0 0.677 H -58.4 -46.2 132.0 0.677 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 132.0 0.677 H -58.3 -46.2 132.0 0.677 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 132.0 0.677 H -58.3 -46.2 132.0 0.677 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 132.0 0.677 H -58.3 -46.2 132.0 0.677 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 132.0 0.677 H -58.3 -46.2 132.0 0.677 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 132.0 0.677 H -58.3 -46.2 132.0 0.677 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 HIS A:298 A:293 126.0 0.646 H -58.9 -47.7 126.0 0.646 0.0 HOH
 2.683
 ND1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 GLN A:291 A:291 118.0 0.656 H -61.9 -42.4
af-p13637-f1 1 P13637 88.37 0.0 GLN A:283 A:283 116.0 0.644 H -61.6 -41.7
af-p05023-f1 1 P05023 86.71 0.0 HIS A:293 A:293 116.0 0.595 H -62.8 -39.7
af-q13733-f1 1 Q13733 80.48 0.0 HIS A:301 A:301 109.0 0.559 H -61.7 -43.2