Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 160097472 | . | C | A | CCDS1196.1:NM_000702.3:c.879atC>atA_NP_000693.1:p.293I>I | Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4xe5 | 1 | Q08DA1 | 86.79 | 0.0 |
X-RAY |
2016-03-09 | ILE | A:293 | A:293 | 1.0 | 0.006 | H | -58.7 | -46.4 | 1.0 | 0.006 | 0.0 |
MG HOH |
9.412 9.000 |
CG2 CG2 |
MG O |
||
| 3wgu | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | ILE | A:288 | A:288 | 11.0 | 0.063 | H | -64.1 | -36.7 | 11.0 | 0.063 | 0.0 |
NA NA PC1 PC1 HOH |
7.762 8.478 4.013 7.063 8.640 |
CG1 CD1 CD1 N CG1 |
NA NA C34 O32 O |
||
| ILE | D:288 | C:288 | 14.0 | 0.08 | H | -73.4 | -30.8 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | ILE | A:288 | A:288 | 13.0 | 0.074 | H | -64.9 | -28.5 | 13.0 | 0.074 | 0.0 |
NA NA PC1 PC1 EFO HOH |
8.456 8.839 3.939 7.073 7.349 8.865 |
CG1 CG1 CD1 N C CG1 |
NA NA C34 O32 C3B O |
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| ILE | D:288 | C:288 | 13.0 | 0.074 | H | -70.7 | -35.6 | NA | NA | NA | |||||||||||||
| 4hqj | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-10-02 | ILE | A:293 | A:288 | 6.0 | 0.034 | H | -57.0 | -49.1 | 6.0 | 0.034 | 0.0 |
NA NA |
7.496 8.784 |
CG2 CG2 |
NA NA |
||
| ILE | D:293 | C:288 | 5.0 | 0.029 | H | -56.5 | -48.7 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-06-26 | ILE | A:293 | A:288 | 1.0 | 0.006 | H | -55.2 | -50.4 | 1.0 | 0.006 | 0.0 |
MG 17F 17F HOH |
9.210 6.634 5.844 8.171 |
CG2 N N CG2 |
MG C6 O6 O |
||
| ILE | D:293 | C:288 | 1.0 | 0.006 | H | -54.8 | -50.6 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | ILE | A:293 | A:288 | 0.0 | 0.0 | H | -63.9 | -44.8 | 0.0 | 0.0 | 0.0 |
K K |
8.127 8.746 |
CD1 CG2 |
K K |
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| ILE | D:293 | C:288 | 0.0 | 0.0 | H | -64.4 | -44.7 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | ILE | A:293 | A:288 | 1.0 | 0.006 | H | -55.1 | -52.5 | 1.0 | 0.006 | 0.0 |
MG 17F 17F HOH |
9.531 5.826 6.484 8.859 |
CG2 N N CG2 |
MG O9 O1 O |
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| ILE | D:293 | C:288 | 1.0 | 0.006 | H | -55.0 | -52.6 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2021-07-07 | ILE | A:293 | A:288 | 1.0 | 0.006 | H | -59.0 | -50.8 | 1.0 | 0.006 | 0.0 |
MG PCW PCW HOH |
9.985 6.536 8.264 7.856 |
CG2 N N CG2 |
MG O11 C1 O |
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| ILE | D:293 | C:288 | 0.0 | 0.0 | H | -61.4 | -46.8 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:288 | A:288 | 1.0 | 0.006 | H | -59.1 | -49.7 | 1.0 | 0.006 | 0.0 |
MG PCW PCW HOH |
9.414 5.353 6.607 9.432 |
CD1 O N CG2 |
MG O11 O2P O |
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| 7d92 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:288 | A:288 | 0.0 | 0.0 | H | -60.4 | -47.6 | 0.0 | 0.0 | 0.0 |
MG PCW HOH |
9.847 6.525 8.283 |
CG2 O CD1 |
MG O11 O |
||
| 7d93 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:288 | A:288 | 0.0 | 0.0 | H | -59.7 | -56.7 | 0.0 | 0.0 | 0.0 |
MG PCW HOH |
9.708 8.650 7.971 |
CG2 N CG2 |
MG O31 O |
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| ILE | C:288 | C:288 | 0.0 | 0.0 | H | -60.4 | -54.3 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:288 | A:288 | 1.0 | 0.006 | H | -58.5 | -57.9 | 1.0 | 0.006 | 0.0 |
MG RB PCW HOH |
8.739 9.438 7.001 9.631 |
CG2 CD1 N CG2 |
MG RB O11 O |
||
| ILE | D:288 | C:288 | 1.0 | 0.006 | H | -60.5 | -54.9 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:288 | A:288 | 1.0 | 0.006 | H | -59.8 | -49.8 | 1.0 | 0.006 | 0.0 |
MG PCW HOH |
9.882 6.695 8.277 |
CG2 N CG2 |
MG O11 O |
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| ILE | D:288 | C:288 | 1.0 | 0.006 | H | -63.8 | -46.3 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:288 | A:288 | 1.0 | 0.006 | H | -56.9 | -58.0 | 1.0 | 0.006 | 0.0 |
PCW PCW HOH |
6.652 7.650 8.315 |
N N CD1 |
O11 C1 O |
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| ILE | D:288 | C:288 | 1.0 | 0.006 | H | -58.9 | -55.5 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:288 | A:288 | 0.0 | 0.0 | H | -56.6 | -55.9 | 0.0 | 0.0 | 0.0 |
MG PCW PCW HOH |
9.867 6.494 8.412 8.046 |
CG2 N N CG2 |
MG O11 O2P O |
||
| ILE | D:288 | C:288 | 1.0 | 0.006 | H | -58.0 | -55.2 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:288 | A:288 | 0.0 | 0.0 | H | -59.2 | -57.5 | 0.0 | 0.0 | 0.0 |
MG PCW PCW HOH |
9.771 7.069 6.129 7.998 |
CG2 N N CG2 |
MG O31 O31 O |
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| ILE | D:288 | C:288 | 1.0 | 0.006 | H | -60.5 | -54.7 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:288 | A:288 | 0.0 | 0.0 | H | -59.2 | -56.2 | 0.0 | 0.0 | 0.0 |
MG PCW HOH |
9.703 6.903 7.873 |
CG2 N CG2 |
MG O11 O |
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| ILE | D:288 | C:288 | 0.0 | 0.0 | H | -61.0 | -53.7 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ILE | A:288 | A:288 | 1.0 | 0.006 | H | -59.3 | -55.2 | 1.0 | 0.006 | 0.0 |
MG PCW PCW HOH |
9.740 6.829 8.232 7.817 |
CG2 N N CG2 |
MG O11 O2P O |
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| ILE | D:288 | C:288 | 1.0 | 0.006 | H | -61.0 | -52.1 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2007-12-18 | ILE | A:270 | A:288 | 1.0 | 0.006 | H | -55.5 | -48.7 | 1.0 | 0.006 | 0.0 |
RB RB |
9.001 8.628 |
CG1 CG2 |
RB RB |
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| ILE | D:270 | C:288 | 4.0 | 0.023 | H | -51.8 | -68.5 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2010-02-16 | ILE | A:270 | A:288 | 2.0 | 0.011 | H | -39.6 | -88.0 | 2.0 | 0.011 | 0.0 |
RB RB |
8.859 8.402 |
CD1 CD1 |
RB RB |
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| ILE | D:270 | C:288 | 3.0 | 0.017 | H | -69.6 | -68.3 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | ILE | A:264 | A:288 | 4.0 | 0.023 | H | -55.2 | -67.4 | 4.0 | 0.023 | 0.0 | ||||||
| ILE | D:264 | C:288 | 4.0 | 0.023 | H | -55.2 | -67.2 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-05-19 | ILE | A:300 | A:295 | 2.0 | 0.011 | H | -66.6 | -39.7 | 2.0 | 0.011 | 0.0 |
K K HOH |
9.209 8.230 3.740 |
CG2 CG2 CG2 |
K K O |
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| 3a3y | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-09-08 | ILE | A:300 | A:295 | 2.0 | 0.011 | H | -57.4 | -57.7 | 2.0 | 0.011 | 0.0 |
K K HOH |
9.495 9.591 9.129 |
CD1 CG2 N |
K K O |
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| 5avq | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 2.0 | 0.011 | H | -66.6 | -39.7 | 2.0 | 0.011 | 0.0 |
K TL K TL |
9.209 9.209 8.231 8.231 |
CG2 CG2 CG2 CG2 |
K TL K TL |
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| 5avr | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 1.0 | 0.006 | H | -66.5 | -39.6 | 1.0 | 0.006 | 0.0 |
K TL K TL |
9.209 9.209 8.230 8.230 |
CG2 CG2 CG2 CG2 |
K TL K TL |
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| 5avs | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 2.0 | 0.011 | H | -66.6 | -39.7 | 2.0 | 0.011 | 0.0 |
K TL TL |
9.209 9.209 8.229 |
CG2 CG2 CG2 |
K TL TL |
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| 5avt | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 2.0 | 0.011 | H | -66.6 | -39.6 | 2.0 | 0.011 | 0.0 |
K TL TL |
9.210 9.210 8.231 |
CG2 CG2 CG2 |
K TL TL |
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| 5avu | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 2.0 | 0.011 | H | -66.7 | -39.6 | 2.0 | 0.011 | 0.0 |
K TL TL |
9.209 9.209 8.230 |
CG2 CG2 CG2 |
K TL TL |
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| 5avv | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 1.0 | 0.006 | H | -66.7 | -39.6 | 1.0 | 0.006 | 0.0 |
TL TL |
9.210 8.230 |
CG2 CG2 |
TL TL |
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| 5avw | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 1.0 | 0.006 | H | -66.6 | -39.7 | 1.0 | 0.006 | 0.0 |
TL TL |
9.209 8.230 |
CG2 CG2 |
TL TL |
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| 5avx | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 1.0 | 0.006 | H | -66.6 | -39.7 | 1.0 | 0.006 | 0.0 |
TL TL |
9.208 8.230 |
CG2 CG2 |
TL TL |
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| 5avy | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 1.0 | 0.006 | H | -66.5 | -39.7 | 1.0 | 0.006 | 0.0 |
TL TL |
9.208 8.230 |
CG2 CG2 |
TL TL |
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| 5avz | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 2.0 | 0.011 | H | -66.6 | -39.7 | 2.0 | 0.011 | 0.0 |
TL TL |
9.209 8.231 |
CG2 CG2 |
TL TL |
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| 5aw0 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 2.0 | 0.011 | H | -66.6 | -39.7 | 2.0 | 0.011 | 0.0 |
TL TL |
9.209 8.230 |
CG2 CG2 |
TL TL |
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| 5aw1 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 2.0 | 0.011 | H | -66.7 | -39.6 | 2.0 | 0.011 | 0.0 |
K TL TL |
9.209 9.209 8.230 |
CG2 CG2 CG2 |
K TL TL |
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| 5aw2 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 2.0 | 0.011 | H | -66.6 | -39.6 | 2.0 | 0.011 | 0.0 |
TL TL |
9.209 8.230 |
CG2 CG2 |
TL TL |
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| 5aw3 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 2.0 | 0.011 | H | -66.6 | -39.7 | 2.0 | 0.011 | 0.0 |
TL TL |
9.210 8.230 |
CG2 CG2 |
TL TL |
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| 5aw4 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 1.0 | 0.006 | H | -66.7 | -39.7 | 1.0 | 0.006 | 0.0 |
K RB K RB |
9.208 9.208 8.229 8.229 |
CG2 CG2 CG2 CG2 |
K RB K RB |
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| 5aw5 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 1.0 | 0.006 | H | -66.6 | -39.7 | 1.0 | 0.006 | 0.0 |
K RB K RB |
9.209 9.209 8.230 8.230 |
CG2 CG2 CG2 CG2 |
K RB K RB |
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| 5aw6 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 2.0 | 0.011 | H | -66.6 | -39.6 | 2.0 | 0.011 | 0.0 |
K RB K RB |
9.209 9.209 8.230 8.230 |
CG2 CG2 CG2 CG2 |
K RB K RB |
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| 5aw7 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 2.0 | 0.011 | H | -66.6 | -39.6 | 2.0 | 0.011 | 0.0 |
K RB RB |
9.210 9.210 8.231 |
CG2 CG2 CG2 |
K RB RB |
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| 5aw8 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 2.0 | 0.011 | H | -66.6 | -39.7 | 2.0 | 0.011 | 0.0 |
RB RB |
9.209 8.230 |
CG2 CG2 |
RB RB |
||
| 5aw9 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ILE | A:300 | A:295 | 0.0 | 0.0 | H | -73.0 | -43.1 | 0.0 | 0.0 | 0.0 |
K K HOH |
9.206 8.234 3.812 |
CG2 CG2 CG2 |
K K O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p50993-f1 | 1 | P50993 | 100.0 | 0.0 | ILE | A:293 | A:293 | 1.0 | 0.006 | H | -65.4 | -42.2 | |
| af-p13637-f1 | 1 | P13637 | 88.37 | 0.0 | ILE | A:285 | A:285 | 0.0 | 0.0 | H | -65.7 | -42.1 | |
| af-p05023-f1 | 1 | P05023 | 86.71 | 0.0 | ILE | A:295 | A:295 | 1.0 | 0.006 | H | -63.8 | -43.9 | |
| af-q13733-f1 | 1 | Q13733 | 80.48 | 0.0 | ILE | A:303 | A:303 | 1.0 | 0.006 | H | -65.1 | -41.1 | |