Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160098476 . G A CCDS1196.1:NM_000702.3:c.1052cGg>cAg_NP_000693.1:p.351R>Q Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 ARG A:351 A:351 165.0 0.733 H -64.1 -31.3 165.0 0.733 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ARG A:346 A:346 208.0 0.924 T -67.2 -6.5 208.0 0.924 0.0
ARG D:346 C:346 187.0 0.831 H -58.3 -39.0 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ARG A:346 A:346 205.0 0.911 T -72.9 -0.6 205.0 0.911 0.0
ARG D:346 C:346 187.0 0.831 H -54.1 -41.0 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 ARG A:351 A:346 200.0 0.889 H -71.3 -29.4 200.0 0.889 0.0
ARG D:351 C:346 197.0 0.876 H -71.9 -28.3 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 ARG A:351 A:346 177.0 0.787 H -59.7 -32.5 177.0 0.787 0.0
ARG D:351 C:346 177.0 0.787 H -59.1 -32.9 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ARG A:351 A:346 199.0 0.884 H -72.0 -33.7 199.0 0.884 0.0
ARG D:351 C:346 198.0 0.88 H -72.1 -34.0 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ARG A:351 A:346 175.0 0.778 H -62.7 -33.1 175.0 0.778 0.0
ARG D:351 C:346 174.0 0.773 H -62.5 -33.4 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 ARG A:351 A:346 163.0 0.724 H -65.6 -33.8 163.0 0.724 0.0 PCW
PCW
 9.660
5.505
 NH2
NH2
 C6
C6
ARG D:351 C:346 162.0 0.72 H -66.2 -33.5 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:346 A:346 187.0 0.831 H -65.3 -33.2 187.0 0.831 0.0 PCW
PCW
PCW
 9.143
3.999
5.643
 NH2
NH2
NH2
 C6
C7
C8
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:346 A:346 174.0 0.773 H -62.6 -32.8 174.0 0.773 0.0 PCW
PCW
 9.356
3.420
 NE
NH2
 C6
C7
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:346 A:346 155.0 0.689 H -68.2 -38.2 155.0 0.689 0.0 PCW
PCW
 8.645
5.841
 NH2
NH2
 O2P
C7
ARG C:346 C:346 160.0 0.711 H -70.4 -39.8 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:346 A:346 156.0 0.693 H -69.5 -37.8 156.0 0.693 0.0 PCW
PCW
 9.617
4.382
 NH2
NH2
 C6
O2P
ARG D:346 C:346 158.0 0.702 H -71.6 -38.8 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:346 A:346 175.0 0.778 H -64.7 -38.6 175.0 0.778 0.0 PCW
PCW
 8.116
3.983
 NH2
NH2
 C6
C6
ARG D:346 C:346 154.0 0.684 H -63.6 -38.7 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:346 A:346 163.0 0.724 H -67.8 -40.4 163.0 0.724 0.0 PCW
PCW
 9.168
5.946
 NH2
NH2
 C6
O2P
ARG D:346 C:346 159.0 0.707 H -67.4 -40.5 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:346 A:346 164.0 0.729 H -65.9 -35.4 164.0 0.729 0.0 PCW
PCW
 9.529
5.134
 NH2
NH2
 O1P
O2P
ARG D:346 C:346 163.0 0.724 H -66.6 -34.2 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:346 A:346 162.0 0.72 H -69.6 -38.5 162.0 0.72 0.0 PCW
PCW
 9.274
7.071
 NH2
NH2
 O1P
O2P
ARG D:346 C:346 160.0 0.711 H -70.9 -39.0 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:346 A:346 168.0 0.747 H -67.4 -34.0 168.0 0.747 0.0 PCW
 6.191
 NH2
 O2P
ARG D:346 C:346 162.0 0.72 H -68.3 -34.3 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:346 A:346 160.0 0.711 H -69.5 -37.9 160.0 0.711 0.0 PCW
PCW
 9.096
6.619
 NH2
NH2
 C6
O2P
ARG D:346 C:346 155.0 0.689 H -70.5 -38.6 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 ARG A:328 A:346 208.0 0.924 G -72.3 -18.0 208.0 0.924 0.0
ARG D:328 C:346 198.0 0.88 G -72.0 -17.6 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 ARG A:328 A:346 195.0 0.867 T -89.6 -23.5 195.0 0.867 0.0
ARG D:328 C:346 191.0 0.849 T -88.8 -23.8 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ARG A:322 A:346 183.0 0.813 T -77.1 -22.8 183.0 0.813 0.0
ARG D:322 C:346 183.0 0.813 T -75.8 -23.1 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 ARG A:358 A:353 192.0 0.853 T -81.9 1.2 192.0 0.853 0.0 HOH
 7.571
 C
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 ARG A:358 A:353 184.0 0.818 T -67.0 -5.9 184.0 0.818 0.0 HOH
 6.879
 C
 O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 193.0 0.858 T -81.9 1.1 193.0 0.858 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 193.0 0.858 T -81.9 1.2 193.0 0.858 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 193.0 0.858 T -81.9 1.2 193.0 0.858 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 193.0 0.858 T -81.9 1.3 193.0 0.858 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 193.0 0.858 T -81.9 1.3 193.0 0.858 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 192.0 0.853 T -81.9 1.2 192.0 0.853 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 193.0 0.858 T -82.0 1.3 193.0 0.858 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 193.0 0.858 T -81.8 1.1 193.0 0.858 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 193.0 0.858 T -82.0 1.2 193.0 0.858 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 193.0 0.858 T -81.9 1.2 193.0 0.858 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 193.0 0.858 T -81.9 1.2 193.0 0.858 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 193.0 0.858 T -81.9 1.3 193.0 0.858 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 194.0 0.862 T -81.9 1.2 194.0 0.862 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 193.0 0.858 T -81.9 1.2 193.0 0.858 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 193.0 0.858 T -81.9 1.2 193.0 0.858 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 193.0 0.858 T -81.9 1.3 193.0 0.858 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 192.0 0.853 T -81.9 1.2 192.0 0.853 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 193.0 0.858 T -81.9 1.3 193.0 0.858 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 192.0 0.853 T -81.9 1.2 192.0 0.853 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:358 A:353 197.0 0.876 T -75.0 -6.9 197.0 0.876 0.0 HOH
 8.117
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 ARG A:351 A:351 215.0 0.956 T -65.3 -21.5
af-p13637-f1 1 P13637 88.37 0.0 ARG A:343 A:343 216.0 0.96 T -66.1 -21.4
af-p05023-f1 1 P05023 86.71 0.0 ARG A:353 A:353 213.0 0.947 T -65.4 -21.7
af-q13733-f1 1 Q13733 80.48 0.0 ARG A:361 A:361 191.0 0.849 H -65.9 -22.5