Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160098551 . C A CCDS1196.1:NM_000702.3:c.1127aCg>aAg_NP_000693.1:p.376T>K Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 THR A:376 A:376 0.0 0.0 I -72.7 126.3 0.0 0.0 0.0 MG
HOH
 2.133
2.965
 O
O
 MG
O
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 THR A:371 A:371 16.0 0.114 I -85.5 120.1 16.0 0.114 0.0 MG
ALF
MG
ADP
HOH
 5.841
2.321
2.892
2.293
2.590
 O
O
O
OG1
O
 MG
F4
MG
O3B
O
THR D:371 C:371 14.0 0.1 I -77.2 132.9 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 THR A:371 A:371 14.0 0.1 I -80.8 121.9 14.0 0.1 0.0 MG
ALF
MG
ADP
HOH
 5.361
2.368
2.361
2.493
3.049
 O
O
O
OG1
O
 MG
F4
MG
O3B
O
THR D:371 C:371 13.0 0.093 I -70.3 135.7 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 THR A:376 A:371 14.0 0.1 I -69.2 129.4 14.0 0.1 0.0 ADP
ALF
MG
 3.817
2.695
2.072
 CB
O
O
 O2B
F3
MG
THR D:376 C:371 13.0 0.093 I -68.6 130.4 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 THR A:376 A:371 0.0 0.0 I -74.1 129.7 0.0 0.0 0.0 MG
 2.080
 O
 MG
THR D:376 C:371 0.0 0.0 I -74.8 129.7 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 THR A:376 A:371 0.0 0.0 B -66.7 129.7 0.0 0.0 0.0 MG
 1.954
 O
 MG
THR D:376 C:371 0.0 0.0 I -67.2 129.8 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 THR A:376 A:371 0.0 0.0 I -70.6 130.7 0.0 0.0 0.0 MG
 2.036
 O
 MG
THR D:376 C:371 0.0 0.0 I -70.9 130.6 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 THR A:376 A:371 0.0 0.0 I -69.1 121.3 0.0 0.0 0.0 MG
HOH
 2.143
3.769
 O
O
 MG
O
THR D:376 C:371 0.0 0.0 I -71.2 122.9 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:371 A:371 0.0 0.0 I -72.4 117.1 0.0 0.0 0.0 MG
HOH
 2.063
3.282
 O
O
 MG
O
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:371 A:371 0.0 0.0 I -71.7 117.1 0.0 0.0 0.0 MG
HOH
 2.038
3.186
 O
O
 MG
O
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:371 A:371 0.0 0.0 I -67.5 118.5 0.0 0.0 0.0 MG
HOH
 2.078
3.619
 O
O
 MG
O
THR C:371 C:371 0.0 0.0 I -67.7 118.9 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:371 A:371 0.0 0.0 I -67.5 117.3 0.0 0.0 0.0 MG
HOH
 2.199
3.598
 O
O
 MG
O
THR D:371 C:371 0.0 0.0 I -68.8 117.4 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:371 A:371 0.0 0.0 I -68.7 118.3 0.0 0.0 0.0 MG
HOH
 2.051
3.315
 O
O
 MG
O
THR D:371 C:371 0.0 0.0 I -68.4 116.2 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:371 A:371 0.0 0.0 I -68.9 120.7 0.0 0.0 0.0 MG
HOH
 2.069
3.193
 O
O
 MG
O
THR D:371 C:371 0.0 0.0 I -68.0 120.5 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:371 A:371 0.0 0.0 I -64.9 124.6 0.0 0.0 0.0 MG
HOH
 2.155
3.936
 O
O
 MG
O
THR D:371 C:371 0.0 0.0 I -65.6 125.9 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:371 A:371 0.0 0.0 I -67.8 117.2 0.0 0.0 0.0 MG
HOH
 2.066
3.472
 O
O
 MG
O
THR D:371 C:371 0.0 0.0 I -66.4 116.7 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:371 A:371 0.0 0.0 I -70.7 117.4 0.0 0.0 0.0 MG
HOH
 2.020
3.291
 O
O
 MG
O
THR D:371 C:371 0.0 0.0 I -69.6 117.7 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:371 A:371 0.0 0.0 I -69.9 117.8 0.0 0.0 0.0 MG
HOH
 2.100
3.653
 O
O
 MG
O
THR D:371 C:371 0.0 0.0 I -69.6 118.5 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 THR A:353 A:371 1.0 0.007 I -62.6 122.0 1.0 0.007 0.0 MG
MF4
 2.371
3.086
 O
N
 MG
F4
THR D:353 C:371 0.0 0.0 I -62.1 121.8 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 THR A:353 A:371 0.0 0.0 I -58.8 123.2 0.0 0.0 0.0 MF4
MG
 2.892
2.481
 N
O
 F4
MG
THR D:353 C:371 1.0 0.007 I -58.6 121.4 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 THR A:347 A:371 1.0 0.007 I -77.5 132.6 1.0 0.007 0.0 MG
 2.733
 O
 MG
THR D:347 C:371 1.0 0.007 I -76.9 132.4 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 THR A:383 A:378 1.0 0.007 I -71.0 114.3 1.0 0.007 0.0 MF4
MG
HOH
 2.846
1.939
2.822
 N
O
O
 F4
MG
O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 THR A:383 A:378 0.0 0.0 I -72.4 117.3 0.0 0.0 0.0 MF4
MG
HOH
 2.599
2.179
3.027
 N
O
OG1
 F4
MG
O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.0 114.3 1.0 0.007 0.0 MF4
MG
 2.847
1.939
 N
O
 F4
MG
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.1 114.3 1.0 0.007 0.0 MF4
MG
 2.847
1.939
 N
O
 F4
MG
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.1 114.3 1.0 0.007 0.0 MF4
MG
 2.847
1.939
 N
O
 F4
MG
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.0 114.3 1.0 0.007 0.0 MF4
MG
 2.847
1.939
 N
O
 F4
MG
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.0 114.3 1.0 0.007 0.0 MF4
MG
 2.847
1.939
 N
O
 F4
MG
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.1 114.4 1.0 0.007 0.0 MF4
MG
 2.847
1.939
 N
O
 F4
MG
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.0 114.3 1.0 0.007 0.0 MF4
MG
 2.846
1.940
 N
O
 F4
MG
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.1 114.4 1.0 0.007 0.0 MF4
MG
 2.847
1.939
 N
O
 F4
MG
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.0 114.4 1.0 0.007 0.0 MF4
MG
 2.846
1.939
 N
O
 F4
MG
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.1 114.3 1.0 0.007 0.0 MF4
MG
 2.846
1.939
 N
O
 F4
MG
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.0 114.3 1.0 0.007 0.0 MF4
MG
 2.846
1.939
 N
O
 F4
MG
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.1 114.3 1.0 0.007 0.0 MF4
MG
 2.847
1.940
 N
O
 F4
MG
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.0 114.3 1.0 0.007 0.0 MF4
MG
 2.847
1.939
 N
O
 F4
MG
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.1 114.3 1.0 0.007 0.0 MF4
MG
 2.847
1.939
 N
O
 F4
MG
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.0 114.4 1.0 0.007 0.0 MF4
MG
 2.846
1.939
 N
O
 F4
MG
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.0 114.3 1.0 0.007 0.0 MF4
MG
 2.846
1.938
 N
O
 F4
MG
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.1 114.4 1.0 0.007 0.0 MF4
MG
 2.845
1.939
 N
O
 F4
MG
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.1 114.4 1.0 0.007 0.0 MF4
MG
 2.846
1.939
 N
O
 F4
MG
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 I -71.1 114.4 1.0 0.007 0.0 MF4
MG
 2.846
1.938
 N
O
 F4
MG
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:383 A:378 1.0 0.007 T -68.4 114.5 1.0 0.007 0.0 MF4
MG
HOH
 2.772
2.105
2.672
 N
O
OG1
 F4
MG
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 THR A:376 A:376 1.0 0.007 I -70.5 126.0
af-p13637-f1 1 P13637 88.37 0.0 THR A:368 A:368 5.0 0.036 I -73.4 129.8
af-p05023-f1 1 P05023 86.71 0.0 THR A:378 A:378 5.0 0.036 I -74.4 129.3
af-q13733-f1 1 Q13733 80.48 0.0 THR A:386 A:386 1.0 0.007 I -69.2 127.7