Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 160098554 | . | G | A | CCDS1196.1:NM_000702.3:c.1130gGc>gAc_NP_000693.1:p.377G>D | Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4xe5 | 1 | Q08DA1 | 86.79 | 0.0 |
X-RAY |
2016-03-09 | GLY | A:377 | A:377 | 0.0 | 0.0 | I | 96.4 | -19.8 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.374 4.797 |
N N |
MG O |
||
| 3wgu | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | GLY | A:372 | A:372 | 0.0 | 0.0 | I | 80.3 | 16.7 | 0.0 | 0.0 | 0.0 |
MG ALF MG ADP HOH |
7.647 4.354 5.184 6.572 4.377 |
N N N N CA |
MG F4 MG O3B O |
||
| GLY | D:372 | C:372 | 0.0 | 0.0 | I | 87.9 | -50.7 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | GLY | A:372 | A:372 | 0.0 | 0.0 | I | 83.2 | 16.2 | 0.0 | 0.0 | 0.0 |
MG ALF MG ADP HOH |
7.073 4.400 4.585 6.474 4.305 |
N N N N CA |
MG F4 MG O3B O |
||
| GLY | D:372 | C:372 | 0.0 | 0.0 | I | 85.7 | -40.4 | NA | NA | NA | |||||||||||||
| 4hqj | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-10-02 | GLY | A:377 | A:372 | 0.0 | 0.0 | I | 87.6 | -18.2 | 0.0 | 0.0 | 0.0 |
ADP ALF MG |
6.538 4.688 4.229 |
N N N |
O2B F3 MG |
||
| GLY | D:377 | C:372 | 0.0 | 0.0 | I | 86.6 | -18.0 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-06-26 | GLY | A:377 | A:372 | 0.0 | 0.0 | I | 86.3 | -20.4 | 0.0 | 0.0 | 0.0 |
MG |
4.267 |
N |
MG |
||
| GLY | D:377 | C:372 | 0.0 | 0.0 | I | 86.4 | -20.1 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | GLY | A:377 | A:372 | 1.0 | 0.013 | T | 75.6 | 4.6 | 1.0 | 0.013 | 0.0 |
MG |
4.141 |
N |
MG |
||
| GLY | D:377 | C:372 | 1.0 | 0.013 | I | 76.1 | 4.6 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | GLY | A:377 | A:372 | 0.0 | 0.0 | I | 79.2 | -13.0 | 0.0 | 0.0 | 0.0 |
MG |
4.153 |
N |
MG |
||
| GLY | D:377 | C:372 | 1.0 | 0.013 | I | 79.4 | -13.2 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2021-07-07 | GLY | A:377 | A:372 | 1.0 | 0.013 | I | 93.7 | -40.2 | 1.0 | 0.013 | 0.0 |
MG HOH |
4.040 5.038 |
CA CA |
MG O |
||
| GLY | D:377 | C:372 | 0.0 | 0.0 | I | 96.8 | -40.2 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:372 | A:372 | 0.0 | 0.0 | I | 100.4 | -41.4 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.186 4.745 |
N CA |
MG O |
||
| 7d92 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:372 | A:372 | 0.0 | 0.0 | I | 97.7 | -43.0 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.164 4.614 |
N CA |
MG O |
||
| 7d93 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:372 | A:372 | 0.0 | 0.0 | I | 85.1 | -19.1 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.164 5.031 |
N N |
MG O |
||
| GLY | C:372 | C:372 | 0.0 | 0.0 | I | 85.6 | -18.5 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:372 | A:372 | 0.0 | 0.0 | I | 86.7 | -18.4 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.368 5.065 |
N CA |
MG O |
||
| GLY | D:372 | C:372 | 0.0 | 0.0 | I | 87.6 | -17.8 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:372 | A:372 | 0.0 | 0.0 | I | 93.7 | -30.3 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.194 4.787 |
N CA |
MG O |
||
| GLY | D:372 | C:372 | 0.0 | 0.0 | I | 93.7 | -29.4 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:372 | A:372 | 0.0 | 0.0 | I | 95.8 | -34.7 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.049 4.495 |
CA CA |
MG O |
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| GLY | D:372 | C:372 | 0.0 | 0.0 | I | 94.0 | -34.3 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:372 | A:372 | 0.0 | 0.0 | I | 92.5 | -45.6 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.058 4.926 |
CA CA |
MG O |
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| GLY | D:372 | C:372 | 0.0 | 0.0 | I | 92.6 | -46.3 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:372 | A:372 | 0.0 | 0.0 | I | 86.4 | -18.6 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.211 5.035 |
N N |
MG O |
||
| GLY | D:372 | C:372 | 0.0 | 0.0 | I | 86.5 | -18.4 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:372 | A:372 | 0.0 | 0.0 | I | 98.8 | -44.2 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.031 4.626 |
CA CA |
MG O |
||
| GLY | D:372 | C:372 | 1.0 | 0.013 | I | 98.8 | -42.4 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:372 | A:372 | 0.0 | 0.0 | I | 89.3 | -20.2 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.220 4.928 |
N CA |
MG O |
||
| GLY | D:372 | C:372 | 0.0 | 0.0 | I | 87.8 | -20.5 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2007-12-18 | GLY | A:354 | A:372 | 2.0 | 0.027 | I | 97.1 | -29.8 | 2.0 | 0.027 | 0.0 |
MG MF4 |
4.379 5.762 |
N N |
MG F4 |
||
| GLY | D:354 | C:372 | 1.0 | 0.013 | I | 96.5 | -29.5 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2010-02-16 | GLY | A:354 | A:372 | 0.0 | 0.0 | I | 85.7 | -30.3 | 0.0 | 0.0 | 0.0 |
MF4 MG |
5.556 4.465 |
N N |
F2 MG |
||
| GLY | D:354 | C:372 | 1.0 | 0.013 | I | 86.1 | -29.4 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | GLY | A:348 | A:372 | 0.0 | 0.0 | I | 85.0 | -22.9 | 0.0 | 0.0 | 0.0 |
MG |
4.835 |
N |
MG |
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| GLY | D:348 | C:372 | 0.0 | 0.0 | I | 84.9 | -23.1 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-05-19 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.2 | -4.2 | 0.0 | 0.0 | 0.0 |
MF4 MG HOH |
4.923 4.178 4.697 |
N N N |
F2 MG O |
||
| 3a3y | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-09-08 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 84.6 | -3.3 | 0.0 | 0.0 | 0.0 |
MF4 MG HOH |
5.140 4.439 5.073 |
N N N |
F2 MG O |
||
| 5avq | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.2 | -4.3 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.923 4.178 |
N N |
F2 MG |
||
| 5avr | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.3 | -4.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.923 4.178 |
N N |
F2 MG |
||
| 5avs | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.2 | -4.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.924 4.177 |
N N |
F2 MG |
||
| 5avt | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.2 | -4.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.924 4.178 |
N N |
F2 MG |
||
| 5avu | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.2 | -4.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.923 4.178 |
N N |
F2 MG |
||
| 5avv | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.1 | -4.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.925 4.179 |
N N |
F2 MG |
||
| 5avw | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.1 | -4.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.923 4.178 |
N N |
F2 MG |
||
| 5avx | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.1 | -4.1 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.924 4.179 |
N N |
F2 MG |
||
| 5avy | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.1 | -4.3 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.922 4.178 |
N N |
F2 MG |
||
| 5avz | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.1 | -4.1 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.924 4.177 |
N N |
F2 MG |
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| 5aw0 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.2 | -4.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.923 4.178 |
N N |
F2 MG |
||
| 5aw1 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.2 | -4.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.923 4.179 |
N N |
F2 MG |
||
| 5aw2 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.2 | -4.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.924 4.178 |
N N |
F2 MG |
||
| 5aw3 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.1 | -4.1 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.924 4.179 |
N N |
F2 MG |
||
| 5aw4 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.1 | -4.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.923 4.178 |
N N |
F2 MG |
||
| 5aw5 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.2 | -4.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.922 4.177 |
N N |
F2 MG |
||
| 5aw6 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.1 | -4.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.922 4.177 |
N N |
F2 MG |
||
| 5aw7 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.3 | -4.4 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.924 4.178 |
N N |
F2 MG |
||
| 5aw8 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | I | 88.1 | -4.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
4.923 4.178 |
N N |
F2 MG |
||
| 5aw9 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:384 | A:379 | 0.0 | 0.0 | T | 88.7 | -7.1 | 0.0 | 0.0 | 0.0 |
MF4 MG HOH |
4.974 4.333 4.723 |
N N N |
F2 MG O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p50993-f1 | 1 | P50993 | 100.0 | 0.0 | GLY | A:377 | A:377 | 0.0 | 0.0 | I | 68.9 | -9.8 | |
| af-p13637-f1 | 1 | P13637 | 88.37 | 0.0 | GLY | A:369 | A:369 | 0.0 | 0.0 | I | 69.7 | -15.4 | |
| af-p05023-f1 | 1 | P05023 | 86.71 | 0.0 | GLY | A:379 | A:379 | 0.0 | 0.0 | I | 70.2 | -15.1 | |
| af-q13733-f1 | 1 | Q13733 | 80.48 | 0.0 | GLY | A:387 | A:387 | 0.0 | 0.0 | I | 67.6 | -8.5 | |