Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160098572 . G A CCDS1196.1:NM_000702.3:c.1148cGc>cAc_NP_000693.1:p.383R>H Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 ARG A:383 A:383 38.0 0.169 -130.2 117.2 38.0 0.169 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ARG A:378 A:378 180.0 0.8 -111.2 71.7 180.0 0.8 0.0 HOH
 3.898
 NE
 O
ARG D:378 C:378 183.0 0.813 -113.2 95.7 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ARG A:378 A:378 180.0 0.8 -114.1 69.3 180.0 0.8 0.0 HOH
 4.430
 NE
 O
ARG D:378 C:378 183.0 0.813 -115.9 84.4 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 ARG A:383 A:378 167.0 0.742 -116.9 133.0 167.0 0.742 0.0
ARG D:383 C:378 167.0 0.742 -116.9 132.3 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 ARG A:383 A:378 41.0 0.182 S -134.0 117.2 41.0 0.182 0.0 MG
 9.975
 N
 MG
ARG D:383 C:378 41.0 0.182 S -133.5 117.4 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ARG A:383 A:378 64.0 0.284 -102.2 110.0 64.0 0.284 0.0 MG
 9.882
 N
 MG
ARG D:383 C:378 61.0 0.271 -113.0 109.4 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ARG A:383 A:378 40.0 0.178 S -133.9 120.5 40.0 0.178 0.0 MG
 9.854
 N
 MG
ARG D:383 C:378 44.0 0.196 S -133.8 120.7 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 ARG A:383 A:378 49.0 0.218 S -161.0 129.5 49.0 0.218 0.0 HOH
 9.760
 N
 O
ARG D:383 C:378 53.0 0.236 S -160.3 129.0 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:378 A:378 35.0 0.156 -156.3 111.2 35.0 0.156 0.0 HOH
 9.805
 N
 O
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:378 A:378 36.0 0.16 S -153.6 114.9 36.0 0.16 0.0 HOH
 9.784
 N
 O
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:378 A:378 55.0 0.244 S -170.5 128.5 55.0 0.244 0.0 MG
HOH
 9.955
9.455
 N
N
 MG
O
ARG C:378 C:378 59.0 0.262 S -171.2 128.1 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:378 A:378 54.0 0.24 S -169.2 129.0 54.0 0.24 0.0 HOH
 9.457
 N
 O
ARG D:378 C:378 56.0 0.249 S -169.2 128.7 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:378 A:378 50.0 0.222 S -161.1 126.6 50.0 0.222 0.0 HOH
 9.707
 N
 O
ARG D:378 C:378 54.0 0.24 S -162.0 127.4 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:378 A:378 54.0 0.24 S -159.6 127.3 54.0 0.24 0.0 HOH
 9.468
 N
 O
ARG D:378 C:378 57.0 0.253 S -158.4 126.5 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:378 A:378 51.0 0.227 S -164.1 128.1 51.0 0.227 0.0 MG
HOH
 9.810
9.664
 N
N
 MG
O
ARG D:378 C:378 53.0 0.236 S -164.7 128.1 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:378 A:378 53.0 0.236 S -167.4 126.3 53.0 0.236 0.0 HOH
 9.598
 N
 O
ARG D:378 C:378 59.0 0.262 S -167.9 127.4 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:378 A:378 52.0 0.231 S -164.6 126.1 52.0 0.231 0.0 HOH
 9.610
 N
 O
ARG D:378 C:378 50.0 0.222 S -162.7 124.4 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:378 A:378 53.0 0.236 S -166.6 126.9 53.0 0.236 0.0 HOH
 9.500
 N
 O
ARG D:378 C:378 58.0 0.258 S -166.5 126.7 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 ARG A:360 A:378 48.0 0.213 S -173.7 115.1 48.0 0.213 0.0
ARG D:360 C:378 47.0 0.209 S -172.4 114.8 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 ARG A:360 A:378 37.0 0.164 -143.1 103.6 37.0 0.164 0.0
ARG D:360 C:378 40.0 0.178 -137.9 101.4 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ARG A:354 A:378 42.0 0.187 S -162.8 111.2 42.0 0.187 0.0
ARG D:354 C:378 41.0 0.182 S -163.0 111.6 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 ARG A:390 A:385 44.0 0.196 S -161.3 116.3 44.0 0.196 0.0 HOH
 2.874
 NE
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 ARG A:390 A:385 41.0 0.182 S -169.8 94.7 41.0 0.182 0.0 HOH
 2.754
 NH1
 O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 44.0 0.196 S -161.3 116.3 44.0 0.196 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 44.0 0.196 S -161.3 116.3 44.0 0.196 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 44.0 0.196 S -161.3 116.3 44.0 0.196 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 44.0 0.196 S -161.3 116.3 44.0 0.196 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 44.0 0.196 S -161.3 116.4 44.0 0.196 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 44.0 0.196 S -161.3 116.4 44.0 0.196 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 44.0 0.196 S -161.4 116.3 44.0 0.196 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 44.0 0.196 S -161.3 116.4 44.0 0.196 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 44.0 0.196 S -161.3 116.4 44.0 0.196 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 44.0 0.196 S -161.3 116.3 44.0 0.196 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 44.0 0.196 S -161.3 116.3 44.0 0.196 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 44.0 0.196 S -161.4 116.4 44.0 0.196 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 44.0 0.196 S -161.3 116.3 44.0 0.196 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 44.0 0.196 S -161.3 116.3 44.0 0.196 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 44.0 0.196 S -161.3 116.3 44.0 0.196 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 44.0 0.196 S -161.3 116.3 44.0 0.196 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 45.0 0.2 S -161.3 116.3 45.0 0.2 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 44.0 0.196 S -161.3 116.3 44.0 0.196 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 44.0 0.196 S -161.4 116.3 44.0 0.196 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:390 A:385 42.0 0.187 S -163.4 111.1 42.0 0.187 0.0 HOH
 2.898
 NE
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 ARG A:383 A:383 42.0 0.187 S -146.8 111.6
af-p13637-f1 1 P13637 88.37 0.0 ARG A:375 A:375 40.0 0.178 S -147.7 114.5
af-p05023-f1 1 P05023 86.71 0.0 ARG A:385 A:385 40.0 0.178 S -148.8 113.8
af-q13733-f1 1 Q13733 80.48 0.0 ARG A:393 A:393 43.0 0.191 S -146.6 112.9