Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 160098580 | . | G | A | CCDS1196.1:NM_000702.3:c.1156Gtc>Atc_NP_000693.1:p.386V>I | Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4xe5 | 1 | Q08DA1 | 86.79 | 0.0 |
X-RAY |
2016-03-09 | VAL | A:386 | A:386 | 5.0 | 0.032 | E | -62.9 | 128.6 | 5.0 | 0.032 | 0.0 | ||||||
| 3wgu | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | VAL | A:381 | A:381 | 12.0 | 0.077 | E | -59.0 | 127.4 | 12.0 | 0.077 | 0.0 | ||||||
| VAL | D:381 | C:381 | 2.0 | 0.013 | E | -59.3 | 135.3 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | VAL | A:381 | A:381 | 10.0 | 0.065 | E | -19.5 | 127.3 | 10.0 | 0.065 | 0.0 |
HOH |
9.734 |
O |
O |
||
| VAL | D:381 | C:381 | 4.0 | 0.026 | E | -65.2 | 127.8 | NA | NA | NA | |||||||||||||
| 4hqj | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-10-02 | VAL | A:386 | A:381 | 1.0 | 0.006 | E | -66.0 | 127.2 | 1.0 | 0.006 | 0.0 | ||||||
| VAL | D:386 | C:381 | 3.0 | 0.019 | E | -64.9 | 127.6 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-06-26 | VAL | A:386 | A:381 | 4.0 | 0.026 | E | -60.7 | 125.5 | 4.0 | 0.026 | 0.0 | ||||||
| VAL | D:386 | C:381 | 3.0 | 0.019 | E | -60.5 | 125.4 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | VAL | A:386 | A:381 | 10.0 | 0.065 | E | -69.5 | 123.4 | 10.0 | 0.065 | 0.0 | ||||||
| VAL | D:386 | C:381 | 10.0 | 0.065 | E | -69.3 | 123.5 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | VAL | A:386 | A:381 | 4.0 | 0.026 | E | -59.8 | 127.3 | 4.0 | 0.026 | 0.0 | ||||||
| VAL | D:386 | C:381 | 4.0 | 0.026 | E | -59.4 | 127.1 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2021-07-07 | VAL | A:386 | A:381 | 4.0 | 0.026 | E | -60.9 | 116.1 | 4.0 | 0.026 | 0.0 | ||||||
| VAL | D:386 | C:381 | 4.0 | 0.026 | E | -60.1 | 116.5 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:381 | A:381 | 3.0 | 0.019 | E | -65.6 | 115.9 | 3.0 | 0.019 | 0.0 | ||||||
| 7d92 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:381 | A:381 | 5.0 | 0.032 | E | -66.4 | 110.8 | 5.0 | 0.032 | 0.0 | ||||||
| 7d93 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:381 | A:381 | 3.0 | 0.019 | E | -62.5 | 110.5 | 3.0 | 0.019 | 0.0 | ||||||
| VAL | C:381 | C:381 | 5.0 | 0.032 | E | -63.4 | 108.9 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:381 | A:381 | 3.0 | 0.019 | E | -62.1 | 110.5 | 3.0 | 0.019 | 0.0 | ||||||
| VAL | D:381 | C:381 | 6.0 | 0.039 | E | -63.3 | 108.9 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:381 | A:381 | 4.0 | 0.026 | E | -63.1 | 122.6 | 4.0 | 0.026 | 0.0 | ||||||
| VAL | D:381 | C:381 | 5.0 | 0.032 | E | -62.6 | 119.6 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:381 | A:381 | 5.0 | 0.032 | E | -60.8 | 111.1 | 5.0 | 0.032 | 0.0 | ||||||
| VAL | D:381 | C:381 | 5.0 | 0.032 | E | -60.8 | 109.9 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:381 | A:381 | 4.0 | 0.026 | E | -60.9 | 116.2 | 4.0 | 0.026 | 0.0 | ||||||
| VAL | D:381 | C:381 | 4.0 | 0.026 | E | -60.7 | 115.2 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:381 | A:381 | 4.0 | 0.026 | E | -61.8 | 110.5 | 4.0 | 0.026 | 0.0 | ||||||
| VAL | D:381 | C:381 | 5.0 | 0.032 | E | -64.0 | 107.9 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:381 | A:381 | 5.0 | 0.032 | E | -62.0 | 116.0 | 5.0 | 0.032 | 0.0 | ||||||
| VAL | D:381 | C:381 | 4.0 | 0.026 | E | -60.3 | 115.9 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | VAL | A:381 | A:381 | 3.0 | 0.019 | E | -62.6 | 110.9 | 3.0 | 0.019 | 0.0 | ||||||
| VAL | D:381 | C:381 | 6.0 | 0.039 | E | -62.3 | 109.5 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2007-12-18 | VAL | A:363 | A:381 | 3.0 | 0.019 | E | -63.0 | 115.4 | 3.0 | 0.019 | 0.0 | ||||||
| VAL | D:363 | C:381 | 4.0 | 0.026 | E | -63.2 | 117.0 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2010-02-16 | VAL | A:363 | A:381 | 8.0 | 0.052 | E | -62.6 | 117.0 | 8.0 | 0.052 | 0.0 | ||||||
| VAL | D:363 | C:381 | 9.0 | 0.058 | E | -60.2 | 119.0 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | VAL | A:357 | A:381 | 3.0 | 0.019 | E | -62.7 | 113.5 | 3.0 | 0.019 | 0.0 | ||||||
| VAL | D:357 | C:381 | 4.0 | 0.026 | E | -61.7 | 113.9 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-05-19 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.4 | 126.4 | 4.0 | 0.026 | 0.0 |
HOH |
2.920 |
N |
O |
||
| 3a3y | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-09-08 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -67.3 | 126.0 | 4.0 | 0.026 | 0.0 |
HOH |
2.871 |
N |
O |
||
| 5avq | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.4 | 126.4 | 4.0 | 0.026 | 0.0 | ||||||
| 5avr | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.4 | 126.4 | 4.0 | 0.026 | 0.0 | ||||||
| 5avs | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.5 | 126.4 | 4.0 | 0.026 | 0.0 | ||||||
| 5avt | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.4 | 126.4 | 4.0 | 0.026 | 0.0 | ||||||
| 5avu | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.3 | 126.4 | 4.0 | 0.026 | 0.0 | ||||||
| 5avv | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.3 | 126.4 | 4.0 | 0.026 | 0.0 | ||||||
| 5avw | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.4 | 126.4 | 4.0 | 0.026 | 0.0 | ||||||
| 5avx | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.4 | 126.5 | 4.0 | 0.026 | 0.0 | ||||||
| 5avy | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.3 | 126.4 | 4.0 | 0.026 | 0.0 | ||||||
| 5avz | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.4 | 126.4 | 4.0 | 0.026 | 0.0 | ||||||
| 5aw0 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.4 | 126.4 | 4.0 | 0.026 | 0.0 | ||||||
| 5aw1 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.4 | 126.4 | 4.0 | 0.026 | 0.0 | ||||||
| 5aw2 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.4 | 126.4 | 4.0 | 0.026 | 0.0 | ||||||
| 5aw3 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.4 | 126.4 | 4.0 | 0.026 | 0.0 | ||||||
| 5aw4 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.5 | 126.4 | 4.0 | 0.026 | 0.0 | ||||||
| 5aw5 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.4 | 126.4 | 4.0 | 0.026 | 0.0 | ||||||
| 5aw6 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.4 | 126.4 | 4.0 | 0.026 | 0.0 | ||||||
| 5aw7 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.3 | 126.5 | 4.0 | 0.026 | 0.0 | ||||||
| 5aw8 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 4.0 | 0.026 | E | -61.4 | 126.5 | 4.0 | 0.026 | 0.0 | ||||||
| 5aw9 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | VAL | A:393 | A:388 | 3.0 | 0.019 | E | -61.3 | 123.9 | 3.0 | 0.019 | 0.0 |
HOH |
3.006 |
N |
O |
||
| 1q3i | 1 | ? | 98.07 | 3e-145 |
X-RAY |
2004-08-03 | VAL | A:4 | A:381 | 16.0 | 0.103 | E | -65.6 | 123.0 | 16.0 | 0.103 | 0.0 |
NI HOH |
8.787 2.717 |
O N |
NI O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p50993-f1 | 1 | P50993 | 100.0 | 0.0 | VAL | A:386 | A:386 | 4.0 | 0.026 | E | -65.5 | 125.5 | |
| af-p13637-f1 | 1 | P13637 | 88.37 | 0.0 | VAL | A:378 | A:378 | 3.0 | 0.019 | E | -64.9 | 127.4 | |
| af-p05023-f1 | 1 | P05023 | 86.71 | 0.0 | VAL | A:388 | A:388 | 4.0 | 0.026 | E | -63.6 | 127.9 | |
| af-q13733-f1 | 1 | Q13733 | 80.48 | 0.0 | VAL | A:396 | A:396 | 1.0 | 0.006 | E | -63.6 | 128.4 | |