Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160098636 . G A CCDS1196.1:NM_000702.3:c.1212caG>caA_NP_000693.1:p.404Q>Q Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 GLN A:404 A:404 74.0 0.411 58.2 50.0 74.0 0.411 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 GLN A:399 A:399 168.0 0.933 S 57.0 9.9 168.0 0.933 0.0 HOH
 9.074
 C
 O
GLN D:399 C:399 127.0 0.706 -100.8 -143.0 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 GLN A:399 A:399 169.0 0.939 S 50.2 13.4 169.0 0.939 0.0 HOH
 8.725
 C
 O
GLN D:399 C:399 123.0 0.683 -103.6 -143.4 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 GLN A:404 A:399 2.0 0.011 -58.9 -40.5 2.0 0.011 0.0
GLN D:404 C:399 157.0 0.872 -50.7 134.5 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 GLN A:404 A:399 70.0 0.389 61.3 49.4 70.0 0.389 0.0
GLN D:404 C:399 69.0 0.383 61.2 49.5 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 GLN A:404 A:399 70.0 0.389 60.7 46.3 70.0 0.389 0.0
GLN D:404 C:399 69.0 0.383 60.5 45.6 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 GLN A:404 A:399 68.0 0.378 58.1 51.7 68.0 0.378 0.0
GLN D:404 C:399 68.0 0.378 57.5 52.3 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 GLN A:404 A:399 57.0 0.317 56.9 69.6 57.0 0.317 0.0
GLN D:404 C:399 54.0 0.3 58.3 70.4 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:399 A:399 68.0 0.378 S 60.7 63.6 68.0 0.378 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:399 A:399 69.0 0.383 S 58.3 62.9 69.0 0.383 0.0
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:399 A:399 56.0 0.311 57.4 69.7 56.0 0.311 0.0
GLN C:399 C:399 58.0 0.322 55.6 69.6 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:399 A:399 55.0 0.306 58.1 70.3 55.0 0.306 0.0
GLN D:399 C:399 59.0 0.328 56.7 69.7 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:399 A:399 60.0 0.333 55.7 63.0 60.0 0.333 0.0
GLN D:399 C:399 60.0 0.333 57.0 64.2 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:399 A:399 61.0 0.339 58.2 73.5 61.0 0.339 0.0
GLN D:399 C:399 63.0 0.35 58.2 73.5 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:399 A:399 49.0 0.272 S 59.3 75.9 49.0 0.272 0.0
GLN D:399 C:399 47.0 0.261 S 59.3 76.1 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:399 A:399 55.0 0.306 57.6 70.2 55.0 0.306 0.0
GLN D:399 C:399 58.0 0.322 55.7 69.9 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:399 A:399 63.0 0.35 58.1 69.4 63.0 0.35 0.0
GLN D:399 C:399 65.0 0.361 57.7 69.4 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:399 A:399 57.0 0.317 57.6 68.2 57.0 0.317 0.0
GLN D:399 C:399 58.0 0.322 57.4 67.5 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 GLN A:381 A:399 100.0 0.556 -148.0 -136.1 100.0 0.556 0.0
GLN D:381 C:399 101.0 0.561 -148.3 -136.1 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 GLN A:381 A:399 67.0 0.372 83.4 56.1 67.0 0.372 0.0
GLN D:381 C:399 67.0 0.372 83.2 55.5 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 GLN A:375 A:399 70.0 0.389 44.4 67.2 70.0 0.389 0.0
GLN D:375 C:399 71.0 0.394 44.6 67.7 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 GLN A:411 A:406 68.0 0.378 54.8 67.4 68.0 0.378 0.0 HOH
 7.777
 NE2
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 GLN A:411 A:406 64.0 0.356 46.0 57.3 64.0 0.356 0.0 HOH
 7.804
 NE2
 O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.8 67.5 68.0 0.378 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.8 67.4 68.0 0.378 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.8 67.4 68.0 0.378 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.7 67.5 68.0 0.378 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.9 67.4 68.0 0.378 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.7 67.5 68.0 0.378 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.7 67.5 68.0 0.378 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.7 67.5 68.0 0.378 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.7 67.5 68.0 0.378 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.9 67.5 68.0 0.378 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.8 67.4 68.0 0.378 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.7 67.5 68.0 0.378 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.8 67.5 68.0 0.378 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.8 67.4 68.0 0.378 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.8 67.4 68.0 0.378 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.7 67.5 68.0 0.378 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.8 67.5 68.0 0.378 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.7 67.5 68.0 0.378 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 68.0 0.378 54.8 67.4 68.0 0.378 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLN A:411 A:406 69.0 0.383 51.7 72.3 69.0 0.383 0.0 HOH
 7.622
 NE2
 O
1q3i 1 ? 98.07 3e-145 X-RAY
 2004-08-03 GLN A:22 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 GLN A:404 A:404 72.0 0.4 60.6 45.7
af-p13637-f1 1 P13637 88.37 0.0 GLN A:396 A:396 73.0 0.406 59.4 47.0
af-p05023-f1 1 P05023 86.71 0.0 GLN A:406 A:406 65.0 0.361 58.0 50.7
af-q13733-f1 1 Q13733 80.48 0.0 GLN A:414 A:414 73.0 0.406 57.4 46.7