Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160098787 . C A CCDS1196.1:NM_000702.3:c.1234Cga>Aga_NP_000693.1:p.412R>R Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 THR A:412 A:412 117.0 0.836 -65.9 -28.5 117.0 0.836 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 THR A:407 A:407 110.0 0.786 T -94.3 -15.3 110.0 0.786 0.0
THR D:407 C:407 118.0 0.843 T -123.3 -1.0 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 THR A:407 A:407 108.0 0.771 T -99.4 -19.9 108.0 0.771 0.0
THR D:407 C:407 115.0 0.821 T -123.5 -6.9 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 THR A:412 A:407 115.0 0.821 S -88.1 -18.6 115.0 0.821 0.0
THR D:412 C:407 115.0 0.821 T -88.5 -18.3 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 THR A:412 A:407 113.0 0.807 -63.3 -38.1 113.0 0.807 0.0
THR D:412 C:407 116.0 0.829 -63.4 -38.0 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 THR A:412 A:407 111.0 0.793 -73.0 -25.4 111.0 0.793 0.0
THR D:412 C:407 109.0 0.779 -72.4 -25.1 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 THR A:412 A:407 113.0 0.807 -63.8 -34.1 113.0 0.807 0.0
THR D:412 C:407 116.0 0.829 -63.8 -34.0 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 THR A:412 A:407 119.0 0.85 -135.8 49.4 119.0 0.85 0.0
THR D:412 C:407 114.0 0.814 -136.3 49.2 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:407 A:407 131.0 0.936 -139.7 -24.6 131.0 0.936 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:407 A:407 128.0 0.914 -136.8 -22.6 128.0 0.914 0.0
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:407 A:407 115.0 0.821 -127.7 4.8 115.0 0.821 0.0
THR C:407 C:407 112.0 0.8 -128.7 3.6 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:407 A:407 114.0 0.814 -128.1 5.0 114.0 0.814 0.0
THR D:407 C:407 113.0 0.807 -128.7 3.5 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:407 A:407 116.0 0.829 -117.8 -19.4 116.0 0.829 0.0
THR D:407 C:407 113.0 0.807 -117.7 -22.1 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:407 A:407 123.0 0.879 -137.7 41.7 123.0 0.879 0.0
THR D:407 C:407 118.0 0.843 -136.1 43.5 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:407 A:407 115.0 0.821 -135.3 3.6 115.0 0.821 0.0
THR D:407 C:407 113.0 0.807 -136.1 3.1 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:407 A:407 114.0 0.814 -127.6 4.8 114.0 0.814 0.0
THR D:407 C:407 112.0 0.8 -128.8 3.3 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:407 A:407 112.0 0.8 -132.5 -25.5 112.0 0.8 0.0
THR D:407 C:407 109.0 0.779 -132.0 -25.1 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:407 A:407 115.0 0.821 -127.7 4.9 115.0 0.821 0.0
THR D:407 C:407 113.0 0.807 -128.2 5.0 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 THR A:389 A:407 113.0 0.807 -95.0 -77.1 113.0 0.807 0.0
THR D:389 C:407 115.0 0.821 -95.0 -76.8 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 THR A:389 A:407 121.0 0.864 -47.5 -48.3 121.0 0.864 0.0
THR D:389 C:407 126.0 0.9 -47.0 -49.9 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 THR A:383 A:407 123.0 0.879 -73.8 -56.2 123.0 0.879 0.0
THR D:383 C:407 122.0 0.871 -73.8 -56.2 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 THR A:419 A:414 124.0 0.886 S -71.5 -51.3 124.0 0.886 0.0
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 THR A:419 A:414 131.0 0.936 -69.0 -43.1 131.0 0.936 0.0
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 124.0 0.886 S -71.5 -51.3 124.0 0.886 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 125.0 0.893 S -71.5 -51.4 125.0 0.893 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 124.0 0.886 S -71.5 -51.3 124.0 0.886 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 124.0 0.886 S -71.5 -51.3 124.0 0.886 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 124.0 0.886 S -71.5 -51.3 124.0 0.886 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 125.0 0.893 S -71.5 -51.2 125.0 0.893 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 125.0 0.893 S -71.5 -51.3 125.0 0.893 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 125.0 0.893 S -71.6 -51.3 125.0 0.893 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 126.0 0.9 S -71.4 -51.4 126.0 0.9 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 124.0 0.886 S -71.5 -51.3 124.0 0.886 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 124.0 0.886 S -71.6 -51.3 124.0 0.886 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 125.0 0.893 S -71.5 -51.3 125.0 0.893 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 125.0 0.893 S -71.5 -51.3 125.0 0.893 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 125.0 0.893 S -71.6 -51.3 125.0 0.893 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 124.0 0.886 S -71.5 -51.3 124.0 0.886 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 125.0 0.893 S -71.5 -51.3 125.0 0.893 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 124.0 0.886 S -71.6 -51.3 124.0 0.886 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 124.0 0.886 S -71.5 -51.3 124.0 0.886 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 124.0 0.886 S -71.5 -51.3 124.0 0.886 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:419 A:414 120.0 0.857 -68.2 -46.4 120.0 0.857 0.0
1q3i 1 ? 98.07 3e-145 X-RAY
 2004-08-03 ARG A:30 A:407 198.0 0.88 -47.3 -53.5 198.0 0.88 0.0 HOH
 3.666
 NH1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 ARG A:412 A:412 210.0 0.933 -81.5 -19.7
af-p13637-f1 1 P13637 88.37 0.0 SER A:404 A:404 95.0 0.826 -81.7 -22.6
af-p05023-f1 1 P05023 86.71 0.0 THR A:414 A:414 120.0 0.857 -85.7 -23.8
af-q13733-f1 1 Q13733 80.48 0.0 SER A:422 A:422 94.0 0.817 T -104.3 -9.9