Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160098815 . G A CCDS1196.1:NM_000702.3:c.1262cGa>cAa_NP_000693.1:p.421R>Q Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 ARG A:421 A:421 66.0 0.293 H -64.8 -41.1 66.0 0.293 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ARG A:416 A:416 28.0 0.124 H -65.0 -48.4 28.0 0.124 0.0 HOH
 8.692
 O
 O
ARG D:416 C:416 22.0 0.098 H -71.7 -43.4 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ARG A:416 A:416 27.0 0.12 H -61.3 -48.1 27.0 0.12 0.0 HOH
 9.088
 O
 O
ARG D:416 C:416 21.0 0.093 H -61.7 -44.5 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 ARG A:421 A:416 30.0 0.133 H -64.7 -46.1 30.0 0.133 0.0
ARG D:421 C:416 29.0 0.129 H -65.0 -46.3 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 ARG A:421 A:416 65.0 0.289 H -65.5 -40.0 65.0 0.289 0.0
ARG D:421 C:416 68.0 0.302 H -65.5 -40.2 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ARG A:421 A:416 47.0 0.209 H -58.8 -51.7 47.0 0.209 0.0
ARG D:421 C:416 46.0 0.204 H -59.2 -51.5 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ARG A:421 A:416 64.0 0.284 H -69.0 -36.3 64.0 0.284 0.0
ARG D:421 C:416 62.0 0.276 H -68.6 -36.5 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 ARG A:421 A:416 41.0 0.182 H -71.6 -38.2 41.0 0.182 0.0
ARG D:421 C:416 50.0 0.222 H -71.0 -38.4 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:416 A:416 81.0 0.36 H -67.9 -48.0 81.0 0.36 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:416 A:416 81.0 0.36 H -68.1 -45.1 81.0 0.36 0.0
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:416 A:416 40.0 0.178 H -75.0 -34.2 40.0 0.178 0.0
ARG C:416 C:416 46.0 0.204 H -74.4 -34.9 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:416 A:416 41.0 0.182 H -75.6 -34.5 41.0 0.182 0.0
ARG D:416 C:416 42.0 0.187 H -75.4 -34.5 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:416 A:416 39.0 0.173 H -74.6 -35.0 39.0 0.173 0.0
ARG D:416 C:416 52.0 0.231 H -76.0 -34.4 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:416 A:416 37.0 0.164 H -78.4 -28.3 37.0 0.164 0.0
ARG D:416 C:416 39.0 0.173 H -78.1 -28.0 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:416 A:416 54.0 0.24 H -70.6 -37.8 54.0 0.24 0.0
ARG D:416 C:416 53.0 0.236 H -71.0 -37.5 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:416 A:416 40.0 0.178 H -74.5 -34.7 40.0 0.178 0.0
ARG D:416 C:416 45.0 0.2 H -74.7 -34.9 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:416 A:416 42.0 0.187 H -72.2 -37.5 42.0 0.187 0.0
ARG D:416 C:416 43.0 0.191 H -71.8 -38.0 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:416 A:416 39.0 0.173 H -74.4 -35.2 39.0 0.173 0.0
ARG D:416 C:416 43.0 0.191 H -74.6 -34.9 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 ARG A:398 A:416 25.0 0.111 H -51.9 -50.2 25.0 0.111 0.0
ARG D:398 C:416 25.0 0.111 H -51.5 -50.4 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 ARG A:398 A:416 31.0 0.138 H -57.6 -53.3 31.0 0.138 0.0
ARG D:398 C:416 32.0 0.142 H -57.2 -53.2 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ARG A:392 A:416 49.0 0.218 H -62.0 -47.8 49.0 0.218 0.0
ARG D:392 C:416 49.0 0.218 H -61.9 -47.9 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 ARG A:428 A:423 57.0 0.253 H -69.5 -38.0 57.0 0.253 0.0 HOH
 3.024
 NE
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 ARG A:428 A:423 66.0 0.293 H -63.2 -43.8 66.0 0.293 0.0
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 58.0 0.258 H -69.5 -38.0 58.0 0.258 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 58.0 0.258 H -69.5 -38.1 58.0 0.258 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 58.0 0.258 H -69.5 -38.0 58.0 0.258 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 58.0 0.258 H -69.4 -38.0 58.0 0.258 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 58.0 0.258 H -69.5 -38.0 58.0 0.258 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 58.0 0.258 H -69.4 -38.1 58.0 0.258 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 58.0 0.258 H -69.4 -38.1 58.0 0.258 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 58.0 0.258 H -69.5 -38.0 58.0 0.258 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 58.0 0.258 H -69.5 -38.1 58.0 0.258 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 58.0 0.258 H -69.5 -38.0 58.0 0.258 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 57.0 0.253 H -69.4 -38.0 57.0 0.253 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 58.0 0.258 H -69.5 -37.9 58.0 0.258 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 57.0 0.253 H -69.5 -38.0 57.0 0.253 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 57.0 0.253 H -69.5 -38.0 57.0 0.253 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 58.0 0.258 H -69.5 -38.1 58.0 0.258 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 57.0 0.253 H -69.4 -38.1 57.0 0.253 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 58.0 0.258 H -69.5 -38.0 58.0 0.258 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 58.0 0.258 H -69.4 -38.1 58.0 0.258 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 58.0 0.258 H -69.4 -38.0 58.0 0.258 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:428 A:423 60.0 0.267 H -68.6 -44.1 60.0 0.267 0.0 HOH
 2.757
 NE
 O
1q3i 1 ? 98.07 3e-145 X-RAY
 2004-08-03 ARG A:39 A:416 29.0 0.129 H -67.0 -44.5 29.0 0.129 0.0 HOH
 3.409
 NE
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 ARG A:421 A:421 42.0 0.187 H -63.0 -45.7
af-p13637-f1 1 P13637 88.37 0.0 HIS A:413 A:413 47.0 0.241 H -63.4 -46.6
af-p05023-f1 1 P05023 86.71 0.0 ARG A:423 A:423 37.0 0.164 H -64.9 -45.1
af-q13733-f1 1 Q13733 80.48 0.0 ARG A:431 A:431 47.0 0.209 H -65.2 -43.5