Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160099134 . A C CCDS1196.1:NM_000702.3:c.1405Aga>Cga_NP_000693.1:p.469R>R Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 ARG A:469 A:469 55.0 0.244 H -76.4 -37.7 55.0 0.244 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ARG A:464 A:464 46.0 0.204 H -72.1 -28.9 46.0 0.204 0.0 HOH
 6.821
 CD
 O
ARG D:464 C:464 43.0 0.191 H -65.2 -23.3 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ARG A:464 A:464 47.0 0.209 H -69.7 -35.4 47.0 0.209 0.0 HOH
 7.362
 NH1
 O
ARG D:464 C:464 42.0 0.187 H -62.9 -26.2 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 ARG A:469 A:464 39.0 0.173 H -76.8 -46.7 39.0 0.173 0.0
ARG D:469 C:464 40.0 0.178 H -76.6 -47.1 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 ARG A:469 A:464 40.0 0.178 H -78.3 -29.1 40.0 0.178 0.0
ARG D:469 C:464 41.0 0.182 H -78.1 -29.3 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ARG A:469 A:464 41.0 0.182 H -74.1 -34.2 41.0 0.182 0.0
ARG D:469 C:464 41.0 0.182 H -74.2 -34.0 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ARG A:469 A:464 42.0 0.187 H -79.1 -30.0 42.0 0.187 0.0
ARG D:469 C:464 40.0 0.178 H -79.3 -30.0 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 ARG A:469 A:464 52.0 0.231 H -88.7 -48.5 52.0 0.231 0.0
ARG D:469 C:464 58.0 0.258 H -87.8 -48.5 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:464 A:464 42.0 0.187 H -76.9 -39.8 42.0 0.187 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:464 A:464 43.0 0.191 H -80.3 -41.3 43.0 0.191 0.0
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:464 A:464 63.0 0.28 H -80.7 -43.2 63.0 0.28 0.0
ARG C:464 C:464 61.0 0.271 H -81.2 -43.3 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:464 A:464 64.0 0.284 H -81.2 -42.8 64.0 0.284 0.0
ARG D:464 C:464 65.0 0.289 H -81.8 -43.8 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:464 A:464 50.0 0.222 H -76.0 -44.2 50.0 0.222 0.0
ARG D:464 C:464 54.0 0.24 H -77.5 -47.3 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:464 A:464 55.0 0.244 H -89.3 -43.7 55.0 0.244 0.0
ARG D:464 C:464 56.0 0.249 H -89.0 -45.5 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:464 A:464 62.0 0.276 H -85.2 -40.3 62.0 0.276 0.0
ARG D:464 C:464 60.0 0.267 H -85.0 -40.4 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:464 A:464 64.0 0.284 H -80.5 -43.1 64.0 0.284 0.0
ARG D:464 C:464 63.0 0.28 H -80.9 -43.7 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:464 A:464 58.0 0.258 H -81.0 -51.1 58.0 0.258 0.0
ARG D:464 C:464 61.0 0.271 H -79.7 -51.4 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:464 A:464 61.0 0.271 H -81.7 -42.3 61.0 0.271 0.0
ARG D:464 C:464 63.0 0.28 H -81.4 -42.3 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 ARG A:446 A:464 53.0 0.236 H -72.4 -30.3 53.0 0.236 0.0
ARG D:446 C:464 55.0 0.244 H -72.5 -29.4 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 ARG A:446 A:464 62.0 0.276 T -133.8 44.8 62.0 0.276 0.0
ARG D:446 C:464 64.0 0.284 T -135.5 45.5 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ARG A:440 A:464 52.0 0.231 H -82.1 -4.3 52.0 0.231 0.0
ARG D:440 C:464 55.0 0.244 H -82.5 -4.3 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 ARG A:476 A:471 50.0 0.222 H -83.7 -5.3 50.0 0.222 0.0 HOH
 8.635
 NH1
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 ARG A:476 A:471 55.0 0.244 H -61.8 -18.2 55.0 0.244 0.0 HOH
 8.388
 NH2
 O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.7 -5.3 50.0 0.222 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.6 -5.4 50.0 0.222 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.6 -5.4 50.0 0.222 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.7 -5.3 50.0 0.222 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.7 -5.3 50.0 0.222 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.7 -5.3 50.0 0.222 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.7 -5.3 50.0 0.222 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.7 -5.3 50.0 0.222 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.8 -5.3 50.0 0.222 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.6 -5.4 50.0 0.222 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.6 -5.4 50.0 0.222 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.6 -5.3 50.0 0.222 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.6 -5.4 50.0 0.222 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.7 -5.3 50.0 0.222 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.7 -5.3 50.0 0.222 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.7 -5.3 50.0 0.222 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.7 -5.3 50.0 0.222 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.8 -5.2 50.0 0.222 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 50.0 0.222 H -83.6 -5.4 50.0 0.222 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:476 A:471 51.0 0.227 H -73.3 -16.2 51.0 0.227 0.0 HOH
 8.482
 NH1
 O
1q3i 1 ? 98.07 3e-145 X-RAY
 2004-08-03 ARG A:87 A:464 50.0 0.222 H -69.5 -25.5 50.0 0.222 0.0 HOH
 3.251
 CG
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 ARG A:469 A:469 48.0 0.213 H -68.8 -39.3
af-p13637-f1 1 P13637 88.37 0.0 ARG A:461 A:461 55.0 0.244 H -67.4 -31.2
af-p05023-f1 1 P05023 86.71 0.0 ARG A:471 A:471 54.0 0.24 H -71.0 -33.0
af-q13733-f1 1 Q13733 80.48 0.0 ARG A:479 A:479 57.0 0.253 H -70.1 -34.0