Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160099144 . A C CCDS1196.1:NM_000702.3:c.1415aAc>aCc_NP_000693.1:p.472N>T Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 TYR A:472 A:472 5.0 0.022 S -96.5 126.6 5.0 0.022 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 TYR A:467 A:467 9.0 0.039 S -105.4 67.9 9.0 0.039 0.0 HOH
 9.104
 O
 O
TYR D:467 C:467 13.0 0.057 S -90.5 74.7 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 TYR A:467 A:467 11.0 0.048 T -101.8 61.8 11.0 0.048 0.0 HOH
 9.790
 O
 O
TYR D:467 C:467 13.0 0.057 T -88.8 63.2 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 TYR A:472 A:467 17.0 0.074 S -90.6 90.6 17.0 0.074 0.0
TYR D:472 C:467 17.0 0.074 S -91.8 89.6 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 TYR A:472 A:467 4.0 0.017 S -89.4 131.6 4.0 0.017 0.0
TYR D:472 C:467 4.0 0.017 S -89.4 131.7 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 TYR A:472 A:467 13.0 0.057 S -114.8 107.5 13.0 0.057 0.0
TYR D:472 C:467 12.0 0.052 S -115.3 107.6 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 TYR A:472 A:467 4.0 0.017 S -88.1 129.9 4.0 0.017 0.0
TYR D:472 C:467 5.0 0.022 S -87.7 129.8 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 TYR A:472 A:467 5.0 0.022 S -83.3 99.1 5.0 0.022 0.0
TYR D:472 C:467 5.0 0.022 S -85.2 100.0 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TYR A:467 A:467 14.0 0.061 S -117.3 85.1 14.0 0.061 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TYR A:467 A:467 12.0 0.052 S -114.1 84.5 12.0 0.052 0.0
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TYR A:467 A:467 5.0 0.022 S -112.8 92.8 5.0 0.022 0.0
TYR C:467 C:467 4.0 0.017 S -112.5 92.3 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TYR A:467 A:467 5.0 0.022 S -113.2 92.5 5.0 0.022 0.0
TYR D:467 C:467 3.0 0.013 S -113.1 92.7 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TYR A:467 A:467 4.0 0.017 S -110.1 96.1 4.0 0.017 0.0
TYR D:467 C:467 2.0 0.009 S -111.4 93.5 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TYR A:467 A:467 4.0 0.017 S -117.6 92.3 4.0 0.017 0.0
TYR D:467 C:467 5.0 0.022 S -117.5 91.8 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TYR A:467 A:467 3.0 0.013 S -112.4 89.4 3.0 0.013 0.0
TYR D:467 C:467 3.0 0.013 S -112.1 89.7 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TYR A:467 A:467 5.0 0.022 S -113.2 93.0 5.0 0.022 0.0
TYR D:467 C:467 3.0 0.013 S -112.4 92.3 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TYR A:467 A:467 4.0 0.017 S -114.7 96.5 4.0 0.017 0.0
TYR D:467 C:467 4.0 0.017 S -114.9 95.9 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 TYR A:467 A:467 4.0 0.017 S -112.7 92.5 4.0 0.017 0.0
TYR D:467 C:467 4.0 0.017 S -113.4 92.4 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 TYR A:449 A:467 17.0 0.074 S -97.5 98.4 17.0 0.074 0.0
TYR D:449 C:467 17.0 0.074 S -97.3 98.1 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 TYR A:449 A:467 18.0 0.078 S -90.0 88.3 18.0 0.078 0.0
TYR D:449 C:467 16.0 0.07 S -90.1 86.7 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 TYR A:443 A:467 22.0 0.096 S -111.7 83.1 22.0 0.096 0.0
TYR D:443 C:467 22.0 0.096 S -111.9 83.6 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 ASN A:479 A:474 0.0 0.0 S -122.3 78.6 0.0 0.0 0.0 HOH
 8.219
 OD1
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 ASN A:479 A:474 2.0 0.013 S -129.7 70.3 2.0 0.013 0.0
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.4 78.6 0.0 0.0 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.3 78.6 0.0 0.0 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.3 78.6 0.0 0.0 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.3 78.5 0.0 0.0 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.3 78.6 0.0 0.0 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.4 78.5 0.0 0.0 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.3 78.6 0.0 0.0 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.3 78.5 0.0 0.0 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.3 78.6 0.0 0.0 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.3 78.6 0.0 0.0 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.4 78.6 0.0 0.0 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.4 78.6 0.0 0.0 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.3 78.6 0.0 0.0 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.3 78.6 0.0 0.0 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.3 78.5 0.0 0.0 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.3 78.6 0.0 0.0 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.3 78.5 0.0 0.0 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.3 78.4 0.0 0.0 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -122.4 78.6 0.0 0.0 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:479 A:474 0.0 0.0 S -123.7 78.9 0.0 0.0 0.0 HOH
 7.987
 OD1
 O
1q3i 1 ? 98.07 3e-145 X-RAY
 2004-08-03 ASN A:90 A:467 0.0 0.0 S -135.3 51.0 0.0 0.0 0.0 HOH
 5.204
 OD1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 ASN A:472 A:472 8.0 0.05 S -126.1 72.3
af-p13637-f1 1 P13637 88.37 0.0 ASN A:464 A:464 4.0 0.025 S -109.0 77.5
af-p05023-f1 1 P05023 86.71 0.0 TYR A:474 A:474 25.0 0.109 S -107.7 76.5
af-q13733-f1 1 Q13733 80.48 0.0 ASN A:482 A:482 11.0 0.069 S -129.1 70.5