Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160099907 . C A CCDS1196.1:NM_000702.3:c.1477Cga>Aga_NP_000693.1:p.493R>R Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 ASN A:493 A:493 34.0 0.212 -104.8 132.5 34.0 0.212 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ASN A:488 A:488 2.0 0.013 -102.7 128.1 2.0 0.013 0.0 HOH
 6.401
 O
 O
ASN D:488 C:488 2.0 0.013 -125.1 120.2 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ASN A:488 A:488 2.0 0.013 -104.7 128.8 2.0 0.013 0.0 HOH
 6.395
 O
 O
ASN D:488 C:488 2.0 0.013 -109.7 124.8 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 ASN A:493 A:488 41.0 0.256 -106.9 81.2 41.0 0.256 0.0
ASN D:493 C:488 40.0 0.25 -107.3 81.4 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 ASN A:493 A:488 43.0 0.269 -87.1 132.6 43.0 0.269 0.0
ASN D:493 C:488 45.0 0.281 -87.0 132.6 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ASN A:493 A:488 28.0 0.175 -117.3 114.7 28.0 0.175 0.0
ASN D:493 C:488 28.0 0.175 -117.7 114.9 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ASN A:493 A:488 41.0 0.256 -105.2 116.5 41.0 0.256 0.0
ASN D:493 C:488 41.0 0.256 -105.2 116.6 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 ASN A:493 A:488 20.0 0.125 -103.4 108.7 20.0 0.125 0.0
ASN D:493 C:488 24.0 0.15 -103.1 109.3 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:488 A:488 41.0 0.256 -83.1 145.3 41.0 0.256 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:488 A:488 34.0 0.212 -87.5 145.5 34.0 0.212 0.0
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:488 A:488 24.0 0.15 -106.7 119.7 24.0 0.15 0.0
ASN C:488 C:488 25.0 0.156 -106.8 119.1 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:488 A:488 24.0 0.15 -106.2 119.3 24.0 0.15 0.0
ASN D:488 C:488 26.0 0.163 -106.6 118.7 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:488 A:488 24.0 0.15 -95.9 118.7 24.0 0.15 0.0
ASN D:488 C:488 28.0 0.175 -95.9 117.4 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:488 A:488 22.0 0.138 -116.9 107.8 22.0 0.138 0.0
ASN D:488 C:488 22.0 0.138 -117.0 108.3 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:488 A:488 20.0 0.125 -106.9 114.7 20.0 0.125 0.0
ASN D:488 C:488 20.0 0.125 -107.5 113.9 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:488 A:488 23.0 0.144 -106.5 119.3 23.0 0.144 0.0
ASN D:488 C:488 25.0 0.156 -106.8 119.6 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:488 A:488 26.0 0.163 -122.3 115.8 26.0 0.163 0.0
ASN D:488 C:488 27.0 0.169 -122.8 115.5 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASN A:488 A:488 23.0 0.144 -105.7 119.1 23.0 0.144 0.0
ASN D:488 C:488 25.0 0.156 -106.0 117.9 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 ASN A:470 A:488 8.0 0.05 -78.4 130.3 8.0 0.05 0.0
ASN D:470 C:488 7.0 0.044 -77.6 130.6 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 ASN A:470 A:488 7.0 0.044 -52.8 140.5 7.0 0.044 0.0
ASN D:470 C:488 8.0 0.05 -51.9 140.1 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ASN A:464 A:488 19.0 0.119 -52.0 133.7 19.0 0.119 0.0
ASN D:464 C:488 18.0 0.113 -52.1 133.6 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 ASN A:500 A:495 15.0 0.094 -49.3 125.4 15.0 0.094 0.0 HOH
 6.881
 ND2
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 ASN A:500 A:495 14.0 0.087 -78.6 132.1 14.0 0.087 0.0
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 16.0 0.1 -49.4 125.4 16.0 0.1 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 16.0 0.1 -49.3 125.4 16.0 0.1 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 16.0 0.1 -49.3 125.4 16.0 0.1 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 16.0 0.1 -49.2 125.4 16.0 0.1 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 16.0 0.1 -49.3 125.4 16.0 0.1 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 16.0 0.1 -49.4 125.4 16.0 0.1 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 16.0 0.1 -49.3 125.4 16.0 0.1 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 16.0 0.1 -49.3 125.4 16.0 0.1 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 16.0 0.1 -49.3 125.3 16.0 0.1 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 16.0 0.1 -49.3 125.4 16.0 0.1 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 16.0 0.1 -49.4 125.4 16.0 0.1 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 16.0 0.1 -49.3 125.5 16.0 0.1 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 16.0 0.1 -49.3 125.4 16.0 0.1 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 16.0 0.1 -49.3 125.4 16.0 0.1 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 16.0 0.1 -49.3 125.3 16.0 0.1 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 16.0 0.1 -49.4 125.5 16.0 0.1 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 16.0 0.1 -49.3 125.4 16.0 0.1 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 16.0 0.1 -49.3 125.3 16.0 0.1 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 15.0 0.094 -49.4 125.4 15.0 0.094 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASN A:500 A:495 15.0 0.094 -65.8 128.6 15.0 0.094 0.0 HOH
 6.990
 ND2
 O
1q3i 1 ? 98.07 3e-145 X-RAY
 2004-08-03 ARG A:111 A:488 50.0 0.222 -49.7 130.3 50.0 0.222 0.0 HOH
 3.153
 NH1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 ARG A:493 A:493 51.0 0.227 -82.0 138.7
af-p13637-f1 1 P13637 88.37 0.0 THR A:485 A:485 24.0 0.171 -69.5 151.9
af-p05023-f1 1 P05023 86.71 0.0 ASN A:495 A:495 14.0 0.087 -88.5 119.2
af-q13733-f1 1 Q13733 80.48 0.0 ARG A:503 A:503 61.0 0.271 -102.2 124.0