Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160100000 . G A CCDS1196.1:NM_000702.3:c.1570Gag>Aag_NP_000693.1:p.524E>K Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 GLU A:525 A:525 110.0 0.579 E -82.5 -175.1 110.0 0.579 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 GLU A:520 A:520 103.0 0.542 E -79.5 135.0 103.0 0.542 0.0 HOH
 8.894
 CA
 O
GLU D:520 C:520 112.0 0.589 E -76.5 120.8 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 GLU A:520 A:520 106.0 0.558 E -90.1 135.4 106.0 0.558 0.0 HOH
 8.786
 CA
 O
GLU D:520 C:520 112.0 0.589 E -85.7 123.2 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 GLU A:525 A:520 102.0 0.537 E -61.8 153.4 102.0 0.537 0.0
GLU D:525 C:520 99.0 0.521 E -62.5 153.3 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 GLU A:525 A:520 96.0 0.505 E -81.5 -178.2 96.0 0.505 0.0
GLU D:525 C:520 96.0 0.505 E -81.4 -178.1 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 GLU A:525 A:520 100.0 0.526 -72.2 -178.1 100.0 0.526 0.0
GLU D:525 C:520 102.0 0.537 -72.0 -177.5 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 GLU A:525 A:520 91.0 0.479 E -82.0 -174.0 91.0 0.479 0.0
GLU D:525 C:520 92.0 0.484 E -82.6 -173.9 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 GLU A:525 A:520 73.0 0.384 E -100.3 153.2 73.0 0.384 0.0
GLU D:525 C:520 72.0 0.379 E -100.6 152.1 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLU A:520 A:520 94.0 0.495 E -112.4 150.4 94.0 0.495 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLU A:520 A:520 99.0 0.521 E -110.6 151.0 99.0 0.521 0.0
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLU A:520 A:520 81.0 0.426 E -110.3 160.4 81.0 0.426 0.0
GLU C:520 C:520 80.0 0.421 E -110.8 161.3 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLU A:520 A:520 80.0 0.421 E -110.7 160.3 80.0 0.421 0.0
GLU D:520 C:520 83.0 0.437 E -110.1 162.3 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLU A:520 A:520 83.0 0.437 E -105.7 152.2 83.0 0.437 0.0
GLU D:520 C:520 84.0 0.442 E -106.2 151.8 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLU A:520 A:520 87.0 0.458 E -109.3 158.2 87.0 0.458 0.0
GLU D:520 C:520 83.0 0.437 E -109.8 158.3 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLU A:520 A:520 78.0 0.411 E -98.9 155.6 78.0 0.411 0.0
GLU D:520 C:520 78.0 0.411 E -99.3 155.8 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLU A:520 A:520 85.0 0.447 E -110.9 160.6 85.0 0.447 0.0
GLU D:520 C:520 83.0 0.437 E -110.5 162.3 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLU A:520 A:520 79.0 0.416 E -103.8 157.7 79.0 0.416 0.0
GLU D:520 C:520 81.0 0.426 E -103.6 158.1 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLU A:520 A:520 82.0 0.432 E -110.6 160.3 82.0 0.432 0.0
GLU D:520 C:520 81.0 0.426 E -110.5 161.3 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 GLU A:502 A:520 113.0 0.595 -148.6 50.3 113.0 0.595 0.0
GLU D:502 C:520 113.0 0.595 -148.7 50.3 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 GLU A:502 A:520 101.0 0.532 -53.0 159.8 101.0 0.532 0.0
GLU D:502 C:520 101.0 0.532 -53.0 159.1 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 GLU A:496 A:520 72.0 0.379 -65.2 177.6 72.0 0.379 0.0
GLU D:496 C:520 74.0 0.389 -65.7 177.6 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 GLU A:532 A:527 101.0 0.532 -69.4 168.1 101.0 0.532 0.0 HOH
 6.930
 OE2
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 GLU A:532 A:527 94.0 0.495 -59.6 175.1 94.0 0.495 0.0
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 101.0 0.532 -69.5 168.1 101.0 0.532 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 101.0 0.532 -69.4 168.1 101.0 0.532 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 101.0 0.532 -69.4 168.0 101.0 0.532 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 101.0 0.532 -69.4 168.1 101.0 0.532 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 101.0 0.532 -69.4 168.1 101.0 0.532 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 101.0 0.532 -69.3 168.1 101.0 0.532 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 101.0 0.532 -69.5 168.1 101.0 0.532 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 102.0 0.537 -69.4 168.1 102.0 0.537 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 102.0 0.537 -69.5 168.1 102.0 0.537 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 101.0 0.532 -69.4 168.1 101.0 0.532 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 101.0 0.532 -69.4 168.1 101.0 0.532 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 100.0 0.526 -69.4 168.1 100.0 0.526 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 100.0 0.526 -69.5 168.1 100.0 0.526 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 100.0 0.526 -69.4 168.1 100.0 0.526 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 101.0 0.532 -69.5 168.1 101.0 0.532 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 101.0 0.532 -69.6 168.1 101.0 0.532 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 101.0 0.532 -69.5 168.1 101.0 0.532 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 101.0 0.532 -69.5 168.1 101.0 0.532 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 101.0 0.532 -69.6 168.1 101.0 0.532 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:532 A:527 105.0 0.553 E -61.2 154.5 105.0 0.553 0.0 HOH
 6.579
 OE2
 O
1q3i 1 ? 98.07 3e-145 X-RAY
 2004-08-03 GLU A:142 A:520 98.0 0.516 E -87.6 122.2 98.0 0.516 0.0 HOH
 3.839
 CG
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 GLU A:524 A:524 105.0 0.553 E -81.6 118.8
af-p13637-f1 1 P13637 88.37 0.0 GLU A:517 A:517 106.0 0.558 E -75.3 127.2
af-p05023-f1 1 P05023 86.71 0.0 GLU A:527 A:527 108.0 0.568 E -75.6 128.5
af-q13733-f1 1 Q13733 80.48 0.0 GLU A:534 A:534 105.0 0.553 E -85.9 121.0