Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 160100072 | . | C | A | CCDS1196.1:NM_000702.3:c.1642Cgt>Agt_NP_000693.1:p.548R>S | Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4xe5 | 1 | Q08DA1 | 86.79 | 0.0 |
X-RAY |
2016-03-09 | ARG | A:549 | A:549 | 63.0 | 0.28 | E | -92.7 | 130.2 | 63.0 | 0.28 | 0.0 | ||||||
| 3wgu | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | ARG | A:544 | A:544 | 49.0 | 0.218 | E | -97.3 | 143.0 | 49.0 | 0.218 | 0.0 |
MG ALF MG ADP HOH |
4.827 5.837 6.828 2.214 3.436 |
NH2 NH2 NH2 NH2 NH1 |
MG F4 MG O2B O |
||
| ARG | D:544 | C:544 | 48.0 | 0.213 | E | -82.2 | 121.2 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | ARG | A:544 | A:544 | 49.0 | 0.218 | E | -85.6 | 131.4 | 49.0 | 0.218 | 0.0 |
MG ALF MG ADP HOH |
4.402 5.390 6.843 2.779 4.175 |
NH2 NH2 NH2 NH2 NH2 |
MG F4 MG O1B O |
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| ARG | D:544 | C:544 | 49.0 | 0.218 | E | -81.4 | 123.9 | NA | NA | NA | |||||||||||||
| 4hqj | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-10-02 | ARG | A:549 | A:544 | 26.0 | 0.116 | E | -72.6 | 130.9 | 26.0 | 0.116 | 0.0 |
ADP ALF MG |
3.451 6.446 7.329 |
NH1 NH1 NH1 |
O2B F3 MG |
||
| ARG | D:549 | C:544 | 24.0 | 0.107 | E | -70.7 | 130.2 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-06-26 | ARG | A:549 | A:544 | 78.0 | 0.347 | E | -102.2 | 128.5 | 78.0 | 0.347 | 0.0 | ||||||
| ARG | D:549 | C:544 | 80.0 | 0.356 | E | -102.3 | 128.5 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | ARG | A:549 | A:544 | 104.0 | 0.462 | E | -74.9 | 143.0 | 104.0 | 0.462 | 0.0 | ||||||
| ARG | D:549 | C:544 | 102.0 | 0.453 | E | -74.9 | 143.0 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | ARG | A:549 | A:544 | 74.0 | 0.329 | E | -103.5 | 125.8 | 74.0 | 0.329 | 0.0 | ||||||
| ARG | D:549 | C:544 | 88.0 | 0.391 | E | -103.1 | 125.7 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2021-07-07 | ARG | A:549 | A:544 | 61.0 | 0.271 | E | -98.4 | 123.5 | 61.0 | 0.271 | 0.0 | ||||||
| ARG | D:549 | C:544 | 59.0 | 0.262 | E | -100.0 | 124.2 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:544 | A:544 | 91.0 | 0.404 | B | -113.2 | 113.9 | 91.0 | 0.404 | 0.0 | ||||||
| 7d92 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:544 | A:544 | 110.0 | 0.489 | B | -110.1 | 109.7 | 110.0 | 0.489 | 0.0 | ||||||
| 7d93 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:544 | A:544 | 77.0 | 0.342 | E | -103.9 | 122.9 | 77.0 | 0.342 | 0.0 | ||||||
| ARG | C:544 | C:544 | 78.0 | 0.347 | E | -105.2 | 123.3 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:544 | A:544 | 79.0 | 0.351 | E | -104.5 | 122.7 | 79.0 | 0.351 | 0.0 | ||||||
| ARG | D:544 | C:544 | 78.0 | 0.347 | E | -103.6 | 122.9 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:544 | A:544 | 64.0 | 0.284 | E | -107.2 | 117.8 | 64.0 | 0.284 | 0.0 | ||||||
| ARG | D:544 | C:544 | 57.0 | 0.253 | E | -107.3 | 119.6 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:544 | A:544 | 83.0 | 0.369 | E | -108.5 | 117.7 | 83.0 | 0.369 | 0.0 | ||||||
| ARG | D:544 | C:544 | 70.0 | 0.311 | E | -108.7 | 118.3 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:544 | A:544 | 69.0 | 0.307 | E | -107.5 | 119.1 | 69.0 | 0.307 | 0.0 | ||||||
| ARG | D:544 | C:544 | 59.0 | 0.262 | E | -107.7 | 119.6 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:544 | A:544 | 79.0 | 0.351 | E | -104.0 | 122.6 | 79.0 | 0.351 | 0.0 | ||||||
| ARG | D:544 | C:544 | 75.0 | 0.333 | E | -104.5 | 123.0 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:544 | A:544 | 67.0 | 0.298 | E | -108.6 | 119.9 | 67.0 | 0.298 | 0.0 | ||||||
| ARG | D:544 | C:544 | 62.0 | 0.276 | E | -108.8 | 120.9 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:544 | A:544 | 78.0 | 0.347 | E | -104.1 | 121.9 | 78.0 | 0.347 | 0.0 | ||||||
| ARG | D:544 | C:544 | 75.0 | 0.333 | E | -104.6 | 122.7 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2007-12-18 | ARG | A:526 | A:544 | 100.0 | 0.444 | E | -80.1 | 140.9 | 100.0 | 0.444 | 0.0 | ||||||
| ARG | D:526 | C:544 | 102.0 | 0.453 | E | -79.7 | 140.8 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2010-02-16 | ARG | A:526 | A:544 | 100.0 | 0.444 | E | -71.6 | 127.5 | 100.0 | 0.444 | 0.0 | ||||||
| ARG | D:526 | C:544 | 103.0 | 0.458 | E | -70.8 | 126.5 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | ARG | A:520 | A:544 | 82.0 | 0.364 | E | -75.7 | 136.9 | 82.0 | 0.364 | 0.0 | ||||||
| ARG | D:520 | C:544 | 82.0 | 0.364 | E | -75.3 | 136.9 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-05-19 | ARG | A:556 | A:551 | 100.0 | 0.444 | E | -81.5 | 121.7 | 100.0 | 0.444 | 0.0 |
HOH |
3.603 |
NH2 |
O |
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| 3a3y | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-09-08 | ARG | A:556 | A:551 | 117.0 | 0.52 | E | -80.4 | 131.8 | 117.0 | 0.52 | 0.0 |
HOH |
6.628 |
CG |
O |
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| 5avq | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 100.0 | 0.444 | E | -81.5 | 121.7 | 100.0 | 0.444 | 0.0 | ||||||
| 5avr | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 99.0 | 0.44 | E | -81.5 | 121.7 | 99.0 | 0.44 | 0.0 | ||||||
| 5avs | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 99.0 | 0.44 | E | -81.4 | 121.7 | 99.0 | 0.44 | 0.0 | ||||||
| 5avt | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 99.0 | 0.44 | E | -81.5 | 121.7 | 99.0 | 0.44 | 0.0 | ||||||
| 5avu | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 99.0 | 0.44 | E | -81.5 | 121.7 | 99.0 | 0.44 | 0.0 | ||||||
| 5avv | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 99.0 | 0.44 | E | -81.5 | 121.8 | 99.0 | 0.44 | 0.0 | ||||||
| 5avw | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 99.0 | 0.44 | E | -81.5 | 121.7 | 99.0 | 0.44 | 0.0 | ||||||
| 5avx | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 99.0 | 0.44 | E | -81.6 | 121.7 | 99.0 | 0.44 | 0.0 | ||||||
| 5avy | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 99.0 | 0.44 | E | -81.5 | 121.8 | 99.0 | 0.44 | 0.0 | ||||||
| 5avz | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 99.0 | 0.44 | E | -81.5 | 121.8 | 99.0 | 0.44 | 0.0 | ||||||
| 5aw0 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 99.0 | 0.44 | E | -81.5 | 121.7 | 99.0 | 0.44 | 0.0 | ||||||
| 5aw1 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 99.0 | 0.44 | E | -81.6 | 121.8 | 99.0 | 0.44 | 0.0 | ||||||
| 5aw2 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 99.0 | 0.44 | E | -81.6 | 121.7 | 99.0 | 0.44 | 0.0 | ||||||
| 5aw3 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 99.0 | 0.44 | E | -81.5 | 121.7 | 99.0 | 0.44 | 0.0 | ||||||
| 5aw4 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 99.0 | 0.44 | E | -81.5 | 121.7 | 99.0 | 0.44 | 0.0 | ||||||
| 5aw5 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 99.0 | 0.44 | E | -81.5 | 121.6 | 99.0 | 0.44 | 0.0 | ||||||
| 5aw6 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 100.0 | 0.444 | E | -81.5 | 121.6 | 100.0 | 0.444 | 0.0 | ||||||
| 5aw7 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 99.0 | 0.44 | E | -81.5 | 121.7 | 99.0 | 0.44 | 0.0 | ||||||
| 5aw8 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 99.0 | 0.44 | E | -81.5 | 121.7 | 99.0 | 0.44 | 0.0 | ||||||
| 5aw9 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:556 | A:551 | 97.0 | 0.431 | E | -86.4 | 124.0 | 97.0 | 0.431 | 0.0 |
HOH |
3.198 |
NH2 |
O |
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| 1q3i | 1 | ? | 98.07 | 3e-145 |
X-RAY |
2004-08-03 | ARG | A:166 | A:544 | 122.0 | 0.542 | E | -75.3 | 119.8 | 122.0 | 0.542 | 0.0 |
HOH |
3.103 |
NH1 |
O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p50993-f1 | 1 | P50993 | 100.0 | 0.0 | ARG | A:548 | A:548 | 110.0 | 0.489 | E | -83.2 | 116.1 | |
| af-p13637-f1 | 1 | P13637 | 88.37 | 0.0 | ARG | A:541 | A:541 | 111.0 | 0.493 | E | -84.4 | 115.8 | |
| af-p05023-f1 | 1 | P05023 | 86.71 | 0.0 | ARG | A:551 | A:551 | 112.0 | 0.498 | E | -83.5 | 117.3 | |
| af-q13733-f1 | 1 | Q13733 | 80.48 | 0.0 | ARG | A:558 | A:558 | 104.0 | 0.462 | E | -84.6 | 118.1 | |