Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 160100226 | . | A | C | CCDS1196.1:NM_000702.3:c.1666Aat>Cat_NP_000693.1:p.556N>H | Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4xe5 | 1 | Q08DA1 | 86.79 | 0.0 |
X-RAY |
2016-03-09 | LEU | A:557 | A:557 | 48.0 | 0.282 | E | -73.6 | 154.8 | 48.0 | 0.282 | 0.0 | ||||||
| 3wgu | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | PHE | A:552 | A:552 | 74.0 | 0.352 | E | -87.0 | 91.4 | 74.0 | 0.352 | 0.0 | ||||||
| PHE | D:552 | C:552 | 72.0 | 0.343 | E | -90.0 | 97.5 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | PHE | A:552 | A:552 | 80.0 | 0.381 | E | -78.7 | 94.6 | 80.0 | 0.381 | 0.0 | ||||||
| PHE | D:552 | C:552 | 73.0 | 0.348 | -90.8 | 95.6 | NA | NA | NA | ||||||||||||||
| 4hqj | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-10-02 | PHE | A:557 | A:552 | 61.0 | 0.29 | E | -75.1 | 100.2 | 61.0 | 0.29 | 0.0 | ||||||
| PHE | D:557 | C:552 | 63.0 | 0.3 | E | -74.4 | 100.3 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-06-26 | PHE | A:557 | A:552 | 75.0 | 0.357 | E | -76.4 | 159.9 | 75.0 | 0.357 | 0.0 | ||||||
| PHE | D:557 | C:552 | 78.0 | 0.371 | E | -76.5 | 159.8 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | PHE | A:557 | A:552 | 33.0 | 0.157 | E | -70.5 | 159.7 | 33.0 | 0.157 | 0.0 | ||||||
| PHE | D:557 | C:552 | 30.0 | 0.143 | E | -70.4 | 159.1 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | PHE | A:557 | A:552 | 71.0 | 0.338 | E | -74.0 | 159.6 | 71.0 | 0.338 | 0.0 | ||||||
| PHE | D:557 | C:552 | 69.0 | 0.329 | E | -74.1 | 159.6 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2021-07-07 | PHE | A:557 | A:552 | 68.0 | 0.324 | E | -90.9 | 108.3 | 68.0 | 0.324 | 0.0 | ||||||
| PHE | D:557 | C:552 | 67.0 | 0.319 | E | -88.6 | 108.2 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | PHE | A:552 | A:552 | 88.0 | 0.419 | -92.0 | 113.3 | 88.0 | 0.419 | 0.0 | |||||||
| 7d92 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | PHE | A:552 | A:552 | 88.0 | 0.419 | -89.0 | 110.9 | 88.0 | 0.419 | 0.0 | |||||||
| 7d93 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | PHE | A:552 | A:552 | 61.0 | 0.29 | E | -89.5 | 112.8 | 61.0 | 0.29 | 0.0 | ||||||
| PHE | C:552 | C:552 | 57.0 | 0.271 | E | -87.7 | 113.6 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | PHE | A:552 | A:552 | 59.0 | 0.281 | E | -89.7 | 112.8 | 59.0 | 0.281 | 0.0 | ||||||
| PHE | D:552 | C:552 | 59.0 | 0.281 | E | -88.0 | 114.2 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | PHE | A:552 | A:552 | 60.0 | 0.286 | E | -88.4 | 118.1 | 60.0 | 0.286 | 0.0 | ||||||
| PHE | D:552 | C:552 | 58.0 | 0.276 | E | -85.1 | 118.1 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | PHE | A:552 | A:552 | 71.0 | 0.338 | E | -77.8 | 140.2 | 71.0 | 0.338 | 0.0 | ||||||
| PHE | D:552 | C:552 | 69.0 | 0.329 | E | -77.4 | 140.5 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | PHE | A:552 | A:552 | 60.0 | 0.286 | E | -87.7 | 122.6 | 60.0 | 0.286 | 0.0 | ||||||
| PHE | D:552 | C:552 | 60.0 | 0.286 | E | -87.6 | 123.0 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | PHE | A:552 | A:552 | 60.0 | 0.286 | E | -89.7 | 112.9 | 60.0 | 0.286 | 0.0 | ||||||
| PHE | D:552 | C:552 | 57.0 | 0.271 | E | -88.2 | 113.7 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | PHE | A:552 | A:552 | 60.0 | 0.286 | E | -92.8 | 119.1 | 60.0 | 0.286 | 0.0 | ||||||
| PHE | D:552 | C:552 | 59.0 | 0.281 | E | -90.7 | 119.5 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | PHE | A:552 | A:552 | 60.0 | 0.286 | E | -89.7 | 112.6 | 60.0 | 0.286 | 0.0 | ||||||
| PHE | D:552 | C:552 | 59.0 | 0.281 | E | -89.3 | 113.4 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2007-12-18 | PHE | A:534 | A:552 | 55.0 | 0.262 | E | -104.1 | 104.1 | 55.0 | 0.262 | 0.0 | ||||||
| PHE | D:534 | C:552 | 57.0 | 0.271 | E | -103.7 | 103.6 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2010-02-16 | PHE | A:534 | A:552 | 66.0 | 0.314 | E | -87.9 | 112.4 | 66.0 | 0.314 | 0.0 | ||||||
| PHE | D:534 | C:552 | 66.0 | 0.314 | E | -86.1 | 112.8 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | PHE | A:528 | A:552 | 88.0 | 0.419 | E | -94.3 | 102.8 | 88.0 | 0.419 | 0.0 | ||||||
| PHE | D:528 | C:552 | 87.0 | 0.414 | E | -92.8 | 102.1 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-05-19 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -78.9 | 102.5 | 45.0 | 0.391 | 0.0 |
HOH |
3.647 |
CB |
O |
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| 3a3y | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-09-08 | ALA | A:564 | A:559 | 46.0 | 0.4 | E | -75.1 | 98.8 | 46.0 | 0.4 | 0.0 | ||||||
| 5avq | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -78.9 | 102.5 | 45.0 | 0.391 | 0.0 | ||||||
| 5avr | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -78.9 | 102.4 | 45.0 | 0.391 | 0.0 | ||||||
| 5avs | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -79.0 | 102.6 | 45.0 | 0.391 | 0.0 | ||||||
| 5avt | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -79.0 | 102.5 | 45.0 | 0.391 | 0.0 | ||||||
| 5avu | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -78.9 | 102.5 | 45.0 | 0.391 | 0.0 | ||||||
| 5avv | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -78.9 | 102.5 | 45.0 | 0.391 | 0.0 | ||||||
| 5avw | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -78.9 | 102.5 | 45.0 | 0.391 | 0.0 | ||||||
| 5avx | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -78.9 | 102.5 | 45.0 | 0.391 | 0.0 | ||||||
| 5avy | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -78.8 | 102.5 | 45.0 | 0.391 | 0.0 | ||||||
| 5avz | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -78.9 | 102.5 | 45.0 | 0.391 | 0.0 | ||||||
| 5aw0 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -79.0 | 102.5 | 45.0 | 0.391 | 0.0 | ||||||
| 5aw1 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -78.9 | 102.5 | 45.0 | 0.391 | 0.0 | ||||||
| 5aw2 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -78.9 | 102.5 | 45.0 | 0.391 | 0.0 | ||||||
| 5aw3 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -78.9 | 102.4 | 45.0 | 0.391 | 0.0 | ||||||
| 5aw4 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -79.0 | 102.5 | 45.0 | 0.391 | 0.0 | ||||||
| 5aw5 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -78.9 | 102.6 | 45.0 | 0.391 | 0.0 | ||||||
| 5aw6 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -78.9 | 102.5 | 45.0 | 0.391 | 0.0 | ||||||
| 5aw7 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -79.0 | 102.5 | 45.0 | 0.391 | 0.0 | ||||||
| 5aw8 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 45.0 | 0.391 | E | -79.0 | 102.5 | 45.0 | 0.391 | 0.0 | ||||||
| 5aw9 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ALA | A:564 | A:559 | 43.0 | 0.374 | E | -74.6 | 107.5 | 43.0 | 0.374 | 0.0 |
HOH |
3.411 |
CB |
O |
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| 1q3i | 1 | ? | 98.07 | 3e-145 |
X-RAY |
2004-08-03 | ASN | A:174 | A:552 | 65.0 | 0.406 | E | -81.2 | 101.2 | 65.0 | 0.406 | 0.0 |
HOH |
2.881 |
OD1 |
O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p50993-f1 | 1 | P50993 | 100.0 | 0.0 | ASN | A:556 | A:556 | 60.0 | 0.375 | E | -77.1 | 112.0 | |
| af-p13637-f1 | 1 | P13637 | 88.37 | 0.0 | TYR | A:549 | A:549 | 80.0 | 0.348 | E | -87.0 | 110.4 | |
| af-p05023-f1 | 1 | P05023 | 86.71 | 0.0 | PHE | A:559 | A:559 | 44.0 | 0.21 | E | -82.0 | 115.2 | |
| af-q13733-f1 | 1 | Q13733 | 80.48 | 0.0 | ASN | A:566 | A:566 | 31.0 | 0.194 | E | -74.6 | 117.5 | |