Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160100230 . T A CCDS1196.1:NM_000702.3:c.1670cTg>cAg_NP_000693.1:p.557L>Q Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 LEU A:558 A:558 8.0 0.047 -110.8 152.6 8.0 0.047 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 LEU A:553 A:553 0.0 0.0 E -47.9 119.3 0.0 0.0 0.0 HOH
 9.466
 O
 O
LEU D:553 C:553 0.0 0.0 -58.3 116.3 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 LEU A:553 A:553 0.0 0.0 -52.2 117.5 0.0 0.0 0.0 HOH
 9.281
 O
 O
LEU D:553 C:553 0.0 0.0 -55.4 115.6 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 LEU A:558 A:553 9.0 0.053 -60.6 144.4 9.0 0.053 0.0
LEU D:558 C:553 8.0 0.047 -61.3 144.3 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 LEU A:558 A:553 3.0 0.018 -111.5 149.3 3.0 0.018 0.0
LEU D:558 C:553 3.0 0.018 -111.5 149.2 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 LEU A:558 A:553 0.0 0.0 E -110.9 150.1 0.0 0.0 0.0
LEU D:558 C:553 0.0 0.0 E -110.9 150.0 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 LEU A:558 A:553 3.0 0.018 -112.8 148.3 3.0 0.018 0.0
LEU D:558 C:553 2.0 0.012 -112.9 148.1 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 LEU A:558 A:553 0.0 0.0 E -69.7 136.9 0.0 0.0 0.0
LEU D:558 C:553 0.0 0.0 E -69.7 135.5 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:553 A:553 8.0 0.047 -76.0 115.8 8.0 0.047 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:553 A:553 2.0 0.012 -74.6 115.7 2.0 0.012 0.0
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:553 A:553 0.0 0.0 E -74.8 131.3 0.0 0.0 0.0
LEU C:553 C:553 0.0 0.0 E -75.0 130.2 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:553 A:553 0.0 0.0 E -74.6 131.6 0.0 0.0 0.0
LEU D:553 C:553 0.0 0.0 E -75.1 130.4 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:553 A:553 0.0 0.0 -80.3 142.3 0.0 0.0 0.0
LEU D:553 C:553 0.0 0.0 -80.0 140.4 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:553 A:553 0.0 0.0 E -101.6 127.3 0.0 0.0 0.0
LEU D:553 C:553 0.0 0.0 E -101.4 127.3 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:553 A:553 0.0 0.0 E -82.2 139.4 0.0 0.0 0.0
LEU D:553 C:553 0.0 0.0 E -82.0 140.2 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:553 A:553 0.0 0.0 E -75.1 131.4 0.0 0.0 0.0
LEU D:553 C:553 0.0 0.0 E -75.4 130.3 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:553 A:553 0.0 0.0 E -82.3 140.8 0.0 0.0 0.0
LEU D:553 C:553 0.0 0.0 E -82.1 140.9 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LEU A:553 A:553 0.0 0.0 E -74.3 130.7 0.0 0.0 0.0
LEU D:553 C:553 0.0 0.0 E -74.3 130.7 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 LEU A:535 A:553 1.0 0.006 E -65.8 117.5 1.0 0.006 0.0
LEU D:535 C:553 1.0 0.006 -65.4 117.5 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 LEU A:535 A:553 1.0 0.006 -71.1 114.1 1.0 0.006 0.0
LEU D:535 C:553 1.0 0.006 -70.6 114.7 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 LEU A:529 A:553 2.0 0.012 -53.3 159.8 2.0 0.012 0.0
LEU D:529 C:553 1.0 0.006 -52.8 159.6 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 LEU A:565 A:560 0.0 0.0 -61.9 142.4 0.0 0.0 0.0 HOH
 5.537
 O
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 LEU A:565 A:560 2.0 0.012 -57.4 141.2 2.0 0.012 0.0
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.9 142.4 0.0 0.0 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.8 142.5 0.0 0.0 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.9 142.5 0.0 0.0 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.9 142.4 0.0 0.0 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.8 142.4 0.0 0.0 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.9 142.4 0.0 0.0 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.9 142.4 0.0 0.0 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.9 142.5 0.0 0.0 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.9 142.4 0.0 0.0 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.8 142.4 0.0 0.0 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.9 142.4 0.0 0.0 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.9 142.4 0.0 0.0 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.9 142.5 0.0 0.0 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.9 142.4 0.0 0.0 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.9 142.4 0.0 0.0 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.9 142.4 0.0 0.0 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.9 142.5 0.0 0.0 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.9 142.4 0.0 0.0 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -61.9 142.5 0.0 0.0 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LEU A:565 A:560 0.0 0.0 -69.0 133.2 0.0 0.0 0.0 HOH
 5.641
 O
 O
1q3i 1 ? 98.07 3e-145 X-RAY
 2004-08-03 LEU A:175 A:553 4.0 0.024 E -61.7 131.5 4.0 0.024 0.0 HOH
 2.473
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 LEU A:557 A:557 4.0 0.024 E -72.6 131.2
af-p13637-f1 1 P13637 88.37 0.0 LEU A:550 A:550 0.0 0.0 E -66.4 130.2
af-p05023-f1 1 P05023 86.71 0.0 LEU A:560 A:560 0.0 0.0 E -76.0 128.2
af-q13733-f1 1 Q13733 80.48 0.0 LEU A:567 A:567 1.0 0.006 -70.9 142.1