Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160100269 . C A CCDS1196.1:NM_000702.3:c.1709aCg>aAg_NP_000693.1:p.570T>K Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 THR A:571 A:571 81.0 0.579 S -88.4 1.0 81.0 0.579 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 THR A:566 A:566 37.0 0.264 T -130.4 8.8 37.0 0.264 0.0
THR D:566 C:566 36.0 0.257 T -94.4 -4.4 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 THR A:566 A:566 38.0 0.271 T -124.0 18.0 38.0 0.271 0.0
THR D:566 C:566 36.0 0.257 T -99.6 -7.8 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 THR A:571 A:566 66.0 0.471 T -84.8 -40.2 66.0 0.471 0.0
THR D:571 C:566 65.0 0.464 T -85.3 -39.2 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 THR A:571 A:566 90.0 0.643 S -87.8 10.5 90.0 0.643 0.0
THR D:571 C:566 72.0 0.514 S -92.5 -10.0 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 THR A:571 A:566 80.0 0.571 S -92.1 4.0 80.0 0.571 0.0
THR D:571 C:566 79.0 0.564 S -84.4 4.3 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 THR A:571 A:566 85.0 0.607 S -89.7 6.1 85.0 0.607 0.0
THR D:571 C:566 87.0 0.621 S -90.0 6.3 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 THR A:571 A:566 85.0 0.607 T -73.0 86.2 85.0 0.607 0.0
THR D:571 C:566 85.0 0.607 T -72.1 84.3 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:566 A:566 86.0 0.614 S -135.6 -24.5 86.0 0.614 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:566 A:566 90.0 0.643 S -132.1 -27.3 90.0 0.643 0.0
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:566 A:566 89.0 0.636 T -73.3 79.9 89.0 0.636 0.0
THR C:566 C:566 88.0 0.629 T -71.8 83.0 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:566 A:566 89.0 0.636 T -72.9 80.0 89.0 0.636 0.0
THR D:566 C:566 86.0 0.614 T -72.7 83.3 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:566 A:566 90.0 0.643 S -82.3 76.8 90.0 0.643 0.0
THR D:566 C:566 95.0 0.679 S -81.9 74.3 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:566 A:566 97.0 0.693 S -76.8 76.1 97.0 0.693 0.0
THR D:566 C:566 98.0 0.7 S -76.1 78.8 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:566 A:566 88.0 0.629 T -72.3 85.8 88.0 0.629 0.0
THR D:566 C:566 91.0 0.65 T -72.5 81.1 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:566 A:566 88.0 0.629 T -72.2 79.4 88.0 0.629 0.0
THR D:566 C:566 86.0 0.614 T -71.6 82.4 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:566 A:566 92.0 0.657 T -72.2 82.6 92.0 0.657 0.0
THR D:566 C:566 90.0 0.643 T -71.7 82.3 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:566 A:566 90.0 0.643 T -73.5 75.3 90.0 0.643 0.0
THR D:566 C:566 89.0 0.636 T -73.9 77.0 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 THR A:548 A:566 66.0 0.471 T -41.1 -103.6 66.0 0.471 0.0
THR D:548 C:566 68.0 0.486 T -41.4 -104.1 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 THR A:548 A:566 54.0 0.386 S -120.4 7.3 54.0 0.386 0.0
THR D:548 C:566 54.0 0.386 S -121.6 4.0 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 THR A:542 A:566 55.0 0.393 T -67.2 -20.5 55.0 0.393 0.0
THR D:542 C:566 55.0 0.393 T -67.2 -20.5 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 ALA A:578 A:573 37.0 0.322 T -82.1 -27.4 37.0 0.322 0.0 HOH
 6.301
 N
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 ALA A:578 A:573 35.0 0.304 T -78.7 0.4 35.0 0.304 0.0
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -82.0 -27.4 37.0 0.322 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -82.0 -27.4 37.0 0.322 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -82.0 -27.4 37.0 0.322 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -82.1 -27.4 37.0 0.322 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -82.0 -27.4 37.0 0.322 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -82.0 -27.4 37.0 0.322 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -82.1 -27.3 37.0 0.322 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -82.1 -27.3 37.0 0.322 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -82.1 -27.3 37.0 0.322 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -82.1 -27.4 37.0 0.322 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -82.2 -27.3 37.0 0.322 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -82.0 -27.4 37.0 0.322 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -82.1 -27.4 37.0 0.322 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -82.1 -27.4 37.0 0.322 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -81.9 -27.4 37.0 0.322 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -82.1 -27.3 37.0 0.322 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -82.1 -27.3 37.0 0.322 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -82.1 -27.3 37.0 0.322 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 37.0 0.322 T -81.9 -27.3 37.0 0.322 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ALA A:578 A:573 31.0 0.27 T -76.7 -35.0 31.0 0.27 0.0 HOH
 6.553
 N
 O
1q3i 1 ? 98.07 3e-145 X-RAY
 2004-08-03 THR A:188 A:566 60.0 0.429 T -58.7 -47.7 60.0 0.429 0.0 HOH
 3.780
 CG2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 THR A:570 A:570 54.0 0.386 T -93.4 -16.6
af-p13637-f1 1 P13637 88.37 0.0 CYS A:563 A:563 41.0 0.304 T -91.8 -18.8
af-p05023-f1 1 P05023 86.71 0.0 THR A:573 A:573 56.0 0.4 T -89.0 -24.2
af-q13733-f1 1 Q13733 80.48 0.0 THR A:579 A:579 51.0 0.364 T -90.8 -17.9