Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160100338 . G A CCDS1196.1:NM_000702.3:c.1778cGg>cAg_NP_000693.1:p.593R>Q Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 ARG A:594 A:594 38.0 0.169 -69.1 154.8 38.0 0.169 0.0 MG
HOH
 8.342
8.614
 NH2
NH2
 MG
O
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ARG A:589 A:589 25.0 0.111 -52.2 135.8 25.0 0.111 0.0 ALF
MG
HOH
 8.618
8.538
3.978
 NH2
NH2
NH1
 F4
MG
O
ARG D:589 C:589 26.0 0.116 -65.9 155.4 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ARG A:589 A:589 26.0 0.116 -64.3 137.1 26.0 0.116 0.0 ALF
MG
HOH
 8.598
7.927
3.582
 NH2
NH2
NH1
 F4
MG
O
ARG D:589 C:589 23.0 0.102 -65.2 155.3 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 ARG A:594 A:589 31.0 0.138 -66.5 147.1 31.0 0.138 0.0 ALF
MG
 9.501
8.399
 NH2
NH2
 F3
MG
ARG D:594 C:589 31.0 0.138 -67.1 148.0 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 ARG A:594 A:589 16.0 0.071 -61.3 146.7 16.0 0.071 0.0 MG
 8.741
 NH2
 MG
ARG D:594 C:589 17.0 0.076 -62.7 144.7 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ARG A:594 A:589 47.0 0.209 -73.8 150.8 47.0 0.209 0.0 MG
 8.889
 NH2
 MG
ARG D:594 C:589 48.0 0.213 -72.8 153.8 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ARG A:594 A:589 19.0 0.084 -62.8 150.3 19.0 0.084 0.0 MG
 8.589
 NH2
 MG
ARG D:594 C:589 17.0 0.076 -63.3 145.8 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 ARG A:594 A:589 17.0 0.076 -64.7 166.5 17.0 0.076 0.0 MG
HOH
 8.002
8.757
 NH2
NH2
 MG
O
ARG D:594 C:589 18.0 0.08 -65.2 164.9 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:589 A:589 17.0 0.076 -65.6 154.1 17.0 0.076 0.0 MG
HOH
 8.160
8.415
 NH2
NH2
 MG
O
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:589 A:589 17.0 0.076 -65.7 152.7 17.0 0.076 0.0 MG
HOH
 8.194
8.334
 NH2
NH2
 MG
O
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:589 A:589 17.0 0.076 -68.1 167.0 17.0 0.076 0.0 MG
HOH
 7.932
8.387
 NH2
NH2
 MG
O
ARG C:589 C:589 17.0 0.076 -70.2 168.4 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:589 A:589 19.0 0.084 -69.4 166.5 19.0 0.084 0.0 MG
HOH
 8.221
8.374
 NH2
NH2
 MG
O
ARG D:589 C:589 18.0 0.08 -70.7 168.0 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:589 A:589 18.0 0.08 -70.2 170.4 18.0 0.08 0.0 MG
HOH
 8.177
8.460
 NH2
NH2
 MG
O
ARG D:589 C:589 21.0 0.093 -70.7 171.6 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:589 A:589 17.0 0.076 -65.7 163.8 17.0 0.076 0.0 MG
HOH
 7.954
8.133
 NH2
NH2
 MG
O
ARG D:589 C:589 18.0 0.08 -66.1 162.2 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:589 A:589 19.0 0.084 -66.1 167.2 19.0 0.084 0.0 MG
HOH
 7.996
8.412
 NH2
NH2
 MG
O
ARG D:589 C:589 17.0 0.076 -66.0 167.2 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:589 A:589 19.0 0.084 -68.7 166.8 19.0 0.084 0.0 MG
HOH
 7.929
8.463
 NH2
NH2
 MG
O
ARG D:589 C:589 18.0 0.08 -70.2 169.2 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:589 A:589 20.0 0.089 -65.7 166.0 20.0 0.089 0.0 MG
HOH
 8.022
8.301
 NH2
NH2
 MG
O
ARG D:589 C:589 20.0 0.089 -65.2 165.4 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ARG A:589 A:589 19.0 0.084 -68.2 166.8 19.0 0.084 0.0 MG
HOH
 8.182
8.270
 NH2
NH2
 MG
O
ARG D:589 C:589 18.0 0.08 -68.3 167.1 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 ARG A:571 A:589 15.0 0.067 -63.4 167.0 15.0 0.067 0.0 MG
 8.898
 NH1
 MG
ARG D:571 C:589 19.0 0.084 -63.4 166.5 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 ARG A:571 A:589 26.0 0.116 -80.7 165.2 26.0 0.116 0.0 MG
 8.961
 NH2
 MG
ARG D:571 C:589 31.0 0.138 -81.3 165.4 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ARG A:565 A:589 26.0 0.116 -76.2 -170.4 26.0 0.116 0.0 MG
 9.935
 NH2
 MG
ARG D:565 C:589 27.0 0.12 -76.2 -170.4 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 ARG A:601 A:596 23.0 0.102 -70.6 146.0 23.0 0.102 0.0 MF4
MG
HOH
 9.430
7.996
2.969
 NH2
NH2
NH1
 F2
MG
O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 ARG A:601 A:596 23.0 0.102 -62.6 151.5 23.0 0.102 0.0 MF4
MG
HOH
 9.844
8.418
3.191
 NH2
NH2
NH2
 F2
MG
O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 23.0 0.102 -70.6 146.0 23.0 0.102 0.0 MF4
MG
 9.430
7.997
 NH2
NH2
 F2
MG
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 22.0 0.098 -70.6 146.0 22.0 0.098 0.0 MF4
MG
 9.430
7.996
 NH2
NH2
 F2
MG
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 22.0 0.098 -70.5 146.0 22.0 0.098 0.0 MF4
MG
 9.431
7.995
 NH2
NH2
 F2
MG
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 23.0 0.102 -70.5 146.0 23.0 0.102 0.0 MF4
MG
 9.431
7.995
 NH2
NH2
 F2
MG
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 23.0 0.102 -70.6 146.0 23.0 0.102 0.0 MF4
MG
 9.430
7.996
 NH2
NH2
 F2
MG
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 22.0 0.098 -70.5 146.0 22.0 0.098 0.0 MF4
MG
 9.430
7.995
 NH2
NH2
 F2
MG
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 22.0 0.098 -70.5 146.0 22.0 0.098 0.0 MF4
MG
 9.430
7.995
 NH2
NH2
 F2
MG
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 22.0 0.098 -70.6 146.0 22.0 0.098 0.0 MF4
MG
 9.431
7.996
 NH2
NH2
 F2
MG
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 22.0 0.098 -70.5 146.0 22.0 0.098 0.0 MF4
MG
 9.429
7.996
 NH2
NH2
 F2
MG
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 23.0 0.102 -70.6 146.0 23.0 0.102 0.0 MF4
MG
 9.431
7.995
 NH2
NH2
 F2
MG
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 22.0 0.098 -70.6 145.9 22.0 0.098 0.0 MF4
MG
 9.431
7.996
 NH2
NH2
 F2
MG
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 22.0 0.098 -70.6 146.0 22.0 0.098 0.0 MF4
MG
 9.429
7.996
 NH2
NH2
 F2
MG
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 22.0 0.098 -70.5 146.0 22.0 0.098 0.0 MF4
MG
 9.430
7.995
 NH2
NH2
 F2
MG
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 22.0 0.098 -70.6 146.0 22.0 0.098 0.0 MF4
MG
 9.430
7.996
 NH2
NH2
 F2
MG
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 22.0 0.098 -70.5 146.0 22.0 0.098 0.0 MF4
MG
 9.430
7.995
 NH2
NH2
 F2
MG
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 22.0 0.098 -70.5 146.0 22.0 0.098 0.0 MF4
MG
 9.429
7.995
 NH2
NH2
 F2
MG
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 23.0 0.102 -70.5 146.0 23.0 0.102 0.0 MF4
MG
 9.429
7.994
 NH2
NH2
 F2
MG
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 22.0 0.098 -70.6 146.0 22.0 0.098 0.0 MF4
MG
 9.430
7.995
 NH2
NH2
 F2
MG
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 23.0 0.102 -70.6 146.0 23.0 0.102 0.0 MF4
MG
 9.431
7.996
 NH2
NH2
 F2
MG
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:601 A:596 25.0 0.111 -67.3 143.0 25.0 0.111 0.0 MF4
MG
HOH
 9.529
8.136
2.953
 NH2
NH2
NH1
 F2
MG
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 ARG A:593 A:593 17.0 0.076 -70.4 148.4
af-p13637-f1 1 P13637 88.37 0.0 ARG A:586 A:586 16.0 0.071 -69.8 148.8
af-p05023-f1 1 P05023 86.71 0.0 ARG A:596 A:596 17.0 0.076 -70.0 149.4
af-q13733-f1 1 Q13733 80.48 0.0 ARG A:602 A:602 23.0 0.102 -70.3 146.2