Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 160104289 | . | G | A | CCDS1196.1:NM_000702.3:c.1843Ggg>Agg_NP_000693.1:p.615G>R | Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4xe5 | 1 | Q08DA1 | 86.79 | 0.0 |
X-RAY |
2016-03-09 | GLY | A:616 | A:616 | 4.0 | 0.053 | S | -99.4 | 10.1 | 4.0 | 0.053 | 0.0 |
MG HOH |
7.039 6.272 |
N N |
MG O |
||
| 3wgu | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | GLY | A:611 | A:611 | 16.0 | 0.213 | S | -88.3 | 7.8 | 16.0 | 0.213 | 0.0 |
MG ALF MG ADP HOH |
7.823 2.797 7.352 3.418 7.491 |
CA N N O N |
MG F3 MG C5' O |
||
| GLY | D:611 | C:611 | 17.0 | 0.227 | S | -108.0 | 15.0 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | GLY | A:611 | A:611 | 12.0 | 0.16 | S | -97.6 | -0.9 | 12.0 | 0.16 | 0.0 |
MG ALF MG ADP HOH |
7.949 3.232 7.371 3.420 9.151 |
N N N CA C |
MG F3 MG O3A O |
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| GLY | D:611 | C:611 | 18.0 | 0.24 | S | -106.8 | 13.2 | NA | NA | NA | |||||||||||||
| 4hqj | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-10-02 | GLY | A:616 | A:611 | 19.0 | 0.253 | S | -107.3 | 12.8 | 19.0 | 0.253 | 0.0 |
ADP ALF MG |
3.105 2.421 7.419 |
O N N |
C5' F4 MG |
||
| GLY | D:616 | C:611 | 22.0 | 0.293 | S | -107.5 | 13.7 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-06-26 | GLY | A:616 | A:611 | 2.0 | 0.027 | S | -95.8 | 1.7 | 2.0 | 0.027 | 0.0 |
MG |
6.564 |
N |
MG |
||
| GLY | D:616 | C:611 | 3.0 | 0.04 | S | -95.2 | 1.5 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | GLY | A:616 | A:611 | 11.0 | 0.147 | S | -88.4 | 2.8 | 11.0 | 0.147 | 0.0 |
MG |
6.861 |
N |
MG |
||
| GLY | D:616 | C:611 | 11.0 | 0.147 | S | -88.3 | 2.8 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | GLY | A:616 | A:611 | 4.0 | 0.053 | S | -94.5 | 4.9 | 4.0 | 0.053 | 0.0 |
MG |
6.974 |
N |
MG |
||
| GLY | D:616 | C:611 | 6.0 | 0.08 | S | -95.5 | 4.5 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2021-07-07 | GLY | A:616 | A:611 | 2.0 | 0.027 | S | -97.7 | 11.7 | 2.0 | 0.027 | 0.0 |
MG HOH |
7.995 6.941 |
N N |
MG O |
||
| GLY | D:616 | C:611 | 0.0 | 0.0 | S | -99.0 | 11.2 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:611 | A:611 | 6.0 | 0.08 | -119.8 | 8.0 | 6.0 | 0.08 | 0.0 |
MG HOH |
7.391 7.102 |
N N |
MG O |
|||
| 7d92 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:611 | A:611 | 6.0 | 0.08 | -120.3 | 13.1 | 6.0 | 0.08 | 0.0 |
MG HOH |
7.520 6.904 |
N N |
MG O |
|||
| 7d93 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:611 | A:611 | 5.0 | 0.067 | S | -92.3 | 4.9 | 5.0 | 0.067 | 0.0 |
MG HOH |
7.966 7.321 |
N N |
MG O |
||
| GLY | C:611 | C:611 | 5.0 | 0.067 | S | -91.8 | 6.0 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:611 | A:611 | 5.0 | 0.067 | S | -92.2 | 4.9 | 5.0 | 0.067 | 0.0 |
MG HOH |
7.745 7.278 |
N N |
MG O |
||
| GLY | D:611 | C:611 | 5.0 | 0.067 | S | -91.8 | 5.4 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:611 | A:611 | 7.0 | 0.093 | -113.2 | 19.3 | 7.0 | 0.093 | 0.0 |
MG HOH |
7.395 6.641 |
N N |
MG O |
|||
| GLY | D:611 | C:611 | 3.0 | 0.04 | S | -113.4 | 18.6 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:611 | A:611 | 1.0 | 0.013 | -114.5 | 31.1 | 1.0 | 0.013 | 0.0 |
MG HOH |
7.967 7.187 |
N N |
MG O |
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| GLY | D:611 | C:611 | 0.0 | 0.0 | S | -113.9 | 31.9 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:611 | A:611 | 1.0 | 0.013 | -107.6 | 22.3 | 1.0 | 0.013 | 0.0 |
MG HOH |
7.911 7.030 |
N N |
MG O |
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| GLY | D:611 | C:611 | 0.0 | 0.0 | -107.7 | 23.0 | NA | NA | NA | ||||||||||||||
| 7ddj | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:611 | A:611 | 6.0 | 0.08 | S | -92.1 | 4.7 | 6.0 | 0.08 | 0.0 |
MG HOH |
7.902 7.275 |
N N |
MG O |
||
| GLY | D:611 | C:611 | 4.0 | 0.053 | S | -91.9 | 5.0 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:611 | A:611 | 1.0 | 0.013 | -104.8 | 21.6 | 1.0 | 0.013 | 0.0 |
MG HOH |
7.957 7.029 |
N N |
MG O |
|||
| GLY | D:611 | C:611 | 0.0 | 0.0 | S | -105.9 | 21.0 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:611 | A:611 | 4.0 | 0.053 | -93.9 | 5.6 | 4.0 | 0.053 | 0.0 |
MG HOH |
7.870 7.269 |
N N |
MG O |
|||
| GLY | D:611 | C:611 | 4.0 | 0.053 | S | -94.0 | 6.0 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2007-12-18 | GLY | A:593 | A:611 | 3.0 | 0.04 | S | -86.7 | -8.3 | 3.0 | 0.04 | 0.0 |
MG MF4 |
7.462 2.820 |
N N |
MG F3 |
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| GLY | D:593 | C:611 | 3.0 | 0.04 | S | -87.8 | -7.4 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2010-02-16 | GLY | A:593 | A:611 | 3.0 | 0.04 | S | -90.2 | 21.6 | 3.0 | 0.04 | 0.0 |
MF4 MG |
3.275 7.548 |
N N |
F3 MG |
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| GLY | D:593 | C:611 | 4.0 | 0.053 | S | -92.3 | 23.7 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | GLY | A:587 | A:611 | 1.0 | 0.013 | S | -88.1 | 18.9 | 1.0 | 0.013 | 0.0 |
MG |
7.124 |
N |
MG |
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| GLY | D:587 | C:611 | 1.0 | 0.013 | S | -88.0 | 18.8 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-05-19 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.7 | -7.7 | 2.0 | 0.027 | 0.0 |
MF4 MG HOH |
3.069 7.420 2.669 |
N N O |
F1 MG O |
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| 3a3y | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-09-08 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -83.5 | -7.8 | 2.0 | 0.027 | 0.0 |
MF4 MG HOH |
3.427 7.458 7.152 |
N N N |
F1 MG O |
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| 5avq | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.7 | -7.8 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.069 7.418 |
N N |
F1 MG |
||
| 5avr | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.7 | -7.7 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.069 7.419 |
N N |
F1 MG |
||
| 5avs | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.7 | -7.6 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.068 7.419 |
N N |
F1 MG |
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| 5avt | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.7 | -7.7 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.069 7.419 |
N N |
F1 MG |
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| 5avu | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.6 | -7.7 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.069 7.419 |
N N |
F1 MG |
||
| 5avv | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.6 | -7.8 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.070 7.420 |
N N |
F1 MG |
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| 5avw | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.6 | -7.7 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.068 7.419 |
N N |
F1 MG |
||
| 5avx | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.6 | -7.7 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.068 7.419 |
N N |
F1 MG |
||
| 5avy | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.7 | -7.7 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.070 7.420 |
N N |
F1 MG |
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| 5avz | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.6 | -7.7 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.070 7.420 |
N N |
F1 MG |
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| 5aw0 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.7 | -7.7 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.070 7.420 |
N N |
F1 MG |
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| 5aw1 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.6 | -7.8 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.069 7.419 |
N N |
F1 MG |
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| 5aw2 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.7 | -7.7 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.069 7.420 |
N N |
F1 MG |
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| 5aw3 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.6 | -7.7 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.069 7.418 |
N N |
F1 MG |
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| 5aw4 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.6 | -7.7 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.069 7.421 |
N N |
F1 MG |
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| 5aw5 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.7 | -7.7 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.070 7.420 |
N N |
F1 MG |
||
| 5aw6 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.8 | -7.7 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.069 7.420 |
N N |
F1 MG |
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| 5aw7 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.6 | -7.8 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.070 7.420 |
N N |
F1 MG |
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| 5aw8 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -79.7 | -7.7 | 2.0 | 0.027 | 0.0 |
MF4 MG |
3.071 7.420 |
N N |
F1 MG |
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| 5aw9 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:623 | A:618 | 2.0 | 0.027 | S | -86.6 | -3.4 | 2.0 | 0.027 | 0.0 |
MF4 MG HOH |
3.097 7.479 2.800 |
N N O |
F1 MG O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p50993-f1 | 1 | P50993 | 100.0 | 0.0 | GLY | A:615 | A:615 | 5.0 | 0.067 | S | -81.9 | -3.9 | |
| af-p13637-f1 | 1 | P13637 | 88.37 | 0.0 | GLY | A:608 | A:608 | 4.0 | 0.053 | S | -80.9 | -6.9 | |
| af-p05023-f1 | 1 | P05023 | 86.71 | 0.0 | GLY | A:618 | A:618 | 4.0 | 0.053 | S | -77.8 | -6.0 | |
| af-q13733-f1 | 1 | Q13733 | 80.48 | 0.0 | GLY | A:624 | A:624 | 6.0 | 0.08 | S | -82.4 | -4.0 | |