Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160104334 . A C CCDS1196.1:NM_000702.3:c.1888Atc>Ctc_NP_000693.1:p.630I>L Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 ILE A:631 A:631 0.0 0.0 S -66.7 -40.6 0.0 0.0 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ILE A:626 A:626 0.0 0.0 S -64.6 -37.3 0.0 0.0 0.0
ILE D:626 C:626 1.0 0.006 S -77.5 -25.8 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ILE A:626 A:626 1.0 0.006 S -69.7 -35.1 1.0 0.006 0.0
ILE D:626 C:626 1.0 0.006 S -75.8 -30.1 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 ILE A:631 A:626 1.0 0.006 S -74.6 -34.1 1.0 0.006 0.0
ILE D:631 C:626 1.0 0.006 S -74.7 -33.2 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 ILE A:631 A:626 0.0 0.0 S -80.3 -36.4 0.0 0.0 0.0
ILE D:631 C:626 0.0 0.0 S -79.3 -35.8 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ILE A:631 A:626 0.0 0.0 S -68.6 -47.3 0.0 0.0 0.0
ILE D:631 C:626 0.0 0.0 S -68.2 -47.8 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ILE A:631 A:626 0.0 0.0 S -73.0 -42.8 0.0 0.0 0.0
ILE D:631 C:626 0.0 0.0 S -73.5 -42.5 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 ILE A:631 A:626 0.0 0.0 S -69.2 -30.6 0.0 0.0 0.0
ILE D:631 C:626 0.0 0.0 S -67.9 -32.4 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:626 A:626 0.0 0.0 S -62.6 -23.7 0.0 0.0 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:626 A:626 0.0 0.0 S -65.7 -24.9 0.0 0.0 0.0
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:626 A:626 0.0 0.0 S -66.9 -40.7 0.0 0.0 0.0
ILE C:626 C:626 0.0 0.0 S -66.5 -41.9 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:626 A:626 0.0 0.0 S -68.0 -40.2 0.0 0.0 0.0
ILE D:626 C:626 0.0 0.0 S -67.1 -42.5 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:626 A:626 0.0 0.0 S -71.2 -37.5 0.0 0.0 0.0
ILE D:626 C:626 0.0 0.0 S -68.6 -38.0 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:626 A:626 0.0 0.0 S -68.9 -22.4 0.0 0.0 0.0
ILE D:626 C:626 0.0 0.0 S -68.7 -23.0 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:626 A:626 0.0 0.0 S -70.9 -31.5 0.0 0.0 0.0
ILE D:626 C:626 0.0 0.0 S -69.6 -32.0 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:626 A:626 0.0 0.0 S -66.6 -41.5 0.0 0.0 0.0
ILE D:626 C:626 0.0 0.0 S -66.8 -43.8 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:626 A:626 0.0 0.0 S -75.0 -25.8 0.0 0.0 0.0
ILE D:626 C:626 0.0 0.0 S -70.1 -26.6 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:626 A:626 0.0 0.0 S -65.8 -39.5 0.0 0.0 0.0
ILE D:626 C:626 0.0 0.0 S -66.7 -40.3 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 ILE A:608 A:626 5.0 0.029 S -36.7 -26.7 5.0 0.029 0.0
ILE D:608 C:626 5.0 0.029 S -36.8 -26.8 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 ILE A:608 A:626 2.0 0.011 S -72.7 -14.8 2.0 0.011 0.0
ILE D:608 C:626 2.0 0.011 S -69.0 -17.1 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ILE A:602 A:626 1.0 0.006 S -67.6 -33.0 1.0 0.006 0.0
ILE D:602 C:626 1.0 0.006 S -68.4 -32.7 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 ILE A:638 A:633 0.0 0.0 S -64.5 -43.8 0.0 0.0 0.0 HOH
 2.652
 O
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 ILE A:638 A:633 1.0 0.006 S -52.9 -41.0 1.0 0.006 0.0 MF4
HOH
 9.797
2.705
 CD1
O
 F4
O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 0.0 0.0 S -64.5 -43.8 0.0 0.0 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 0.0 0.0 S -64.4 -43.7 0.0 0.0 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 0.0 0.0 S -64.5 -43.8 0.0 0.0 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 0.0 0.0 S -64.4 -43.8 0.0 0.0 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 0.0 0.0 S -64.5 -43.8 0.0 0.0 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 1.0 0.006 S -64.4 -43.8 1.0 0.006 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 0.0 0.0 S -64.4 -43.7 0.0 0.0 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 1.0 0.006 S -64.5 -43.8 1.0 0.006 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 1.0 0.006 S -64.5 -43.8 1.0 0.006 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 0.0 0.0 S -64.5 -43.8 0.0 0.0 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 0.0 0.0 S -64.5 -43.8 0.0 0.0 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 1.0 0.006 S -64.6 -43.7 1.0 0.006 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 0.0 0.0 S -64.5 -43.7 0.0 0.0 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 0.0 0.0 S -64.6 -43.7 0.0 0.0 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 1.0 0.006 S -64.5 -43.8 1.0 0.006 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 1.0 0.006 S -64.5 -43.7 1.0 0.006 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 1.0 0.006 S -64.6 -43.8 1.0 0.006 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 0.0 0.0 S -64.5 -43.7 0.0 0.0 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 1.0 0.006 S -64.6 -43.7 1.0 0.006 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:638 A:633 0.0 0.0 S -63.8 -45.2 0.0 0.0 0.0 HOH
 2.675
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 ILE A:630 A:630 2.0 0.011 S -71.3 -46.4
af-p13637-f1 1 P13637 88.37 0.0 ILE A:623 A:623 2.0 0.011 S -70.7 -46.2
af-p05023-f1 1 P05023 86.71 0.0 ILE A:633 A:633 2.0 0.011 S -71.9 -46.5
af-q13733-f1 1 Q13733 80.48 0.0 ILE A:639 A:639 2.0 0.011 S -71.0 -45.0