Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 160105036 | . | G | A | CCDS1196.1:NM_000702.3:c.2066cGa>cAa_NP_000693.1:p.689R>Q | Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4xe5 | 1 | Q08DA1 | 86.79 | 0.0 |
X-RAY |
2016-03-09 | ARG | A:690 | A:690 | 65.0 | 0.289 | S | 55.9 | 43.2 | 65.0 | 0.289 | 0.0 | ||||||
| 3wgu | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | ARG | A:685 | A:685 | 14.0 | 0.062 | T | 57.0 | 39.8 | 14.0 | 0.062 | 0.0 |
ALF ADP HOH |
7.235 2.899 9.826 |
N NH2 NH2 |
F3 O3' O |
||
| ARG | D:685 | C:685 | 14.0 | 0.062 | S | 41.9 | 42.8 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | ARG | A:685 | A:685 | 14.0 | 0.062 | S | 47.0 | 45.3 | 14.0 | 0.062 | 0.0 |
ALF ADP |
7.611 2.865 |
N NH2 |
F3 O2' |
||
| ARG | D:685 | C:685 | 14.0 | 0.062 | S | 37.2 | 51.0 | NA | NA | NA | |||||||||||||
| 4hqj | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-10-02 | ARG | A:690 | A:685 | 11.0 | 0.049 | S | 61.8 | 27.8 | 11.0 | 0.049 | 0.0 |
ADP ALF |
2.362 6.554 |
NH2 N |
O3' F4 |
||
| ARG | D:690 | C:685 | 10.0 | 0.044 | S | 63.0 | 27.6 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-06-26 | ARG | A:690 | A:685 | 38.0 | 0.169 | S | 62.1 | 40.6 | 38.0 | 0.169 | 0.0 | ||||||
| ARG | D:690 | C:685 | 48.0 | 0.213 | S | 61.7 | 40.4 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | ARG | A:690 | A:685 | 80.0 | 0.356 | S | 64.3 | 26.9 | 80.0 | 0.356 | 0.0 | ||||||
| ARG | D:690 | C:685 | 81.0 | 0.36 | S | 64.1 | 26.9 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | ARG | A:690 | A:685 | 51.0 | 0.227 | S | 56.8 | 50.9 | 51.0 | 0.227 | 0.0 | ||||||
| ARG | D:690 | C:685 | 61.0 | 0.271 | S | 57.0 | 50.6 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2021-07-07 | ARG | A:690 | A:685 | 48.0 | 0.213 | S | 56.6 | 33.8 | 48.0 | 0.213 | 0.0 | ||||||
| ARG | D:690 | C:685 | 24.0 | 0.107 | S | 56.9 | 32.3 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:685 | A:685 | 68.0 | 0.302 | S | 54.2 | 47.4 | 68.0 | 0.302 | 0.0 | ||||||
| 7d92 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:685 | A:685 | 66.0 | 0.293 | S | 53.4 | 45.3 | 66.0 | 0.293 | 0.0 | ||||||
| 7d93 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:685 | A:685 | 55.0 | 0.244 | S | 58.0 | 38.2 | 55.0 | 0.244 | 0.0 | ||||||
| ARG | C:685 | C:685 | 32.0 | 0.142 | S | 58.9 | 38.1 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:685 | A:685 | 52.0 | 0.231 | S | 57.0 | 37.1 | 52.0 | 0.231 | 0.0 | ||||||
| ARG | D:685 | C:685 | 34.0 | 0.151 | S | 58.2 | 37.1 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:685 | A:685 | 53.0 | 0.236 | S | 59.2 | 34.6 | 53.0 | 0.236 | 0.0 | ||||||
| ARG | D:685 | C:685 | 31.0 | 0.138 | S | 58.3 | 33.0 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:685 | A:685 | 47.0 | 0.209 | S | 55.5 | 37.5 | 47.0 | 0.209 | 0.0 | ||||||
| ARG | D:685 | C:685 | 33.0 | 0.147 | S | 55.4 | 37.2 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:685 | A:685 | 45.0 | 0.2 | S | 57.2 | 33.8 | 45.0 | 0.2 | 0.0 | ||||||
| ARG | D:685 | C:685 | 27.0 | 0.12 | S | 56.8 | 32.8 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:685 | A:685 | 54.0 | 0.24 | S | 57.8 | 37.9 | 54.0 | 0.24 | 0.0 | ||||||
| ARG | D:685 | C:685 | 31.0 | 0.138 | S | 59.0 | 37.4 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:685 | A:685 | 42.0 | 0.187 | S | 56.1 | 36.4 | 42.0 | 0.187 | 0.0 | ||||||
| ARG | D:685 | C:685 | 19.0 | 0.084 | S | 56.1 | 34.7 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ARG | A:685 | A:685 | 52.0 | 0.231 | S | 57.3 | 37.2 | 52.0 | 0.231 | 0.0 | ||||||
| ARG | D:685 | C:685 | 33.0 | 0.147 | S | 57.5 | 36.9 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2007-12-18 | ARG | A:667 | A:685 | 30.0 | 0.133 | S | 37.8 | 85.1 | 30.0 | 0.133 | 0.0 |
MF4 |
6.709 |
N |
F3 |
||
| ARG | D:667 | C:685 | 27.0 | 0.12 | S | 37.6 | 85.6 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2010-02-16 | ARG | A:667 | A:685 | 33.0 | 0.147 | S | 31.8 | 95.2 | 33.0 | 0.147 | 0.0 |
MF4 |
7.062 |
NH1 |
F3 |
||
| ARG | D:667 | C:685 | 33.0 | 0.147 | S | 31.0 | 95.5 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | ARG | A:661 | A:685 | 22.0 | 0.098 | S | 43.2 | 38.4 | 22.0 | 0.098 | 0.0 | ||||||
| ARG | D:661 | C:685 | 22.0 | 0.098 | S | 42.6 | 38.8 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-05-19 | ARG | A:697 | A:692 | 31.0 | 0.138 | S | 54.0 | 36.5 | 31.0 | 0.138 | 0.0 |
MF4 HOH |
6.423 3.158 |
NH1 NH1 |
F3 O |
||
| 3a3y | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-09-08 | ARG | A:697 | A:692 | 26.0 | 0.116 | S | 54.5 | 33.8 | 26.0 | 0.116 | 0.0 |
MF4 HOH |
6.294 3.358 |
NH1 O |
F3 O |
||
| 5avq | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 30.0 | 0.133 | S | 54.0 | 36.5 | 30.0 | 0.133 | 0.0 |
MF4 |
6.423 |
NH1 |
F3 |
||
| 5avr | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 30.0 | 0.133 | S | 54.0 | 36.5 | 30.0 | 0.133 | 0.0 |
MF4 |
6.423 |
NH1 |
F3 |
||
| 5avs | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 30.0 | 0.133 | S | 54.0 | 36.4 | 30.0 | 0.133 | 0.0 |
MF4 |
6.423 |
NH1 |
F3 |
||
| 5avt | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 31.0 | 0.138 | S | 54.1 | 36.4 | 31.0 | 0.138 | 0.0 |
MF4 |
6.423 |
NH1 |
F3 |
||
| 5avu | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 30.0 | 0.133 | S | 54.0 | 36.4 | 30.0 | 0.133 | 0.0 |
MF4 |
6.424 |
NH1 |
F3 |
||
| 5avv | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 31.0 | 0.138 | S | 54.0 | 36.5 | 31.0 | 0.138 | 0.0 |
MF4 |
6.423 |
NH1 |
F3 |
||
| 5avw | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 30.0 | 0.133 | S | 54.0 | 36.5 | 30.0 | 0.133 | 0.0 |
MF4 |
6.424 |
NH1 |
F3 |
||
| 5avx | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 31.0 | 0.138 | S | 54.0 | 36.5 | 31.0 | 0.138 | 0.0 |
MF4 |
6.423 |
NH1 |
F3 |
||
| 5avy | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 31.0 | 0.138 | S | 54.0 | 36.6 | 31.0 | 0.138 | 0.0 |
MF4 |
6.424 |
NH1 |
F3 |
||
| 5avz | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 31.0 | 0.138 | S | 54.0 | 36.5 | 31.0 | 0.138 | 0.0 |
MF4 |
6.424 |
NH1 |
F3 |
||
| 5aw0 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 30.0 | 0.133 | S | 54.0 | 36.6 | 30.0 | 0.133 | 0.0 |
MF4 |
6.424 |
NH1 |
F3 |
||
| 5aw1 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 31.0 | 0.138 | S | 54.1 | 36.5 | 31.0 | 0.138 | 0.0 |
MF4 |
6.423 |
NH1 |
F3 |
||
| 5aw2 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 31.0 | 0.138 | S | 54.0 | 36.5 | 31.0 | 0.138 | 0.0 |
MF4 |
6.424 |
NH1 |
F3 |
||
| 5aw3 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 31.0 | 0.138 | S | 54.0 | 36.5 | 31.0 | 0.138 | 0.0 |
MF4 |
6.424 |
NH1 |
F3 |
||
| 5aw4 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 30.0 | 0.133 | S | 54.0 | 36.5 | 30.0 | 0.133 | 0.0 |
MF4 |
6.424 |
NH1 |
F3 |
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| 5aw5 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 31.0 | 0.138 | S | 54.1 | 36.5 | 31.0 | 0.138 | 0.0 |
MF4 |
6.423 |
NH1 |
F3 |
||
| 5aw6 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 30.0 | 0.133 | S | 54.1 | 36.4 | 30.0 | 0.133 | 0.0 |
MF4 |
6.425 |
NH1 |
F3 |
||
| 5aw7 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 30.0 | 0.133 | S | 54.0 | 36.5 | 30.0 | 0.133 | 0.0 |
MF4 |
6.425 |
NH1 |
F3 |
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| 5aw8 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 30.0 | 0.133 | S | 54.1 | 36.4 | 30.0 | 0.133 | 0.0 |
MF4 |
6.423 |
NH1 |
F3 |
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| 5aw9 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ARG | A:697 | A:692 | 30.0 | 0.133 | S | 58.7 | 32.9 | 30.0 | 0.133 | 0.0 |
MF4 HOH |
6.317 2.992 |
NH1 NH1 |
F3 O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p50993-f1 | 1 | P50993 | 100.0 | 0.0 | ARG | A:689 | A:689 | 86.0 | 0.382 | S | 53.7 | 35.7 | |
| af-p13637-f1 | 1 | P13637 | 88.37 | 0.0 | ARG | A:682 | A:682 | 72.0 | 0.32 | S | 52.7 | 36.3 | |
| af-p05023-f1 | 1 | P05023 | 86.71 | 0.0 | ARG | A:692 | A:692 | 71.0 | 0.316 | S | 53.5 | 33.8 | |
| af-q13733-f1 | 1 | Q13733 | 80.48 | 0.0 | ARG | A:698 | A:698 | 90.0 | 0.4 | S | 52.8 | 36.3 | |