Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160105042 . C A CCDS1196.1:NM_000702.3:c.2072tCt>tAt_NP_000693.1:p.691S>Y Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 SER A:692 A:692 19.0 0.165 -73.0 162.3 19.0 0.165 0.0 HOH
 8.925
 C
 O
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 SER A:687 A:687 33.0 0.287 -75.0 163.7 33.0 0.287 0.0 ALF
ADP
 7.365
6.234
 O
CA
 F3
O2A
SER D:687 C:687 35.0 0.304 -72.4 156.4 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 SER A:687 A:687 34.0 0.296 -52.4 154.6 34.0 0.296 0.0 ALF
ADP
 7.564
6.056
 O
CA
 F3
O1A
SER D:687 C:687 34.0 0.296 -76.0 153.1 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 SER A:692 A:687 24.0 0.209 -79.0 162.9 24.0 0.209 0.0 ADP
ALF
 6.651
8.004
 CA
N
 O2A
F4
SER D:692 C:687 24.0 0.209 -78.6 162.7 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 SER A:692 A:687 11.0 0.096 -65.4 155.9 11.0 0.096 0.0
SER D:692 C:687 13.0 0.113 -65.3 155.9 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 SER A:692 A:687 9.0 0.078 -80.5 156.3 9.0 0.078 0.0
SER D:692 C:687 11.0 0.096 -81.2 156.5 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 SER A:692 A:687 12.0 0.104 -68.6 156.2 12.0 0.104 0.0
SER D:692 C:687 13.0 0.113 -68.0 156.2 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 SER A:692 A:687 8.0 0.07 -65.8 161.3 8.0 0.07 0.0 HOH
 9.443
 C
 O
SER D:692 C:687 2.0 0.017 -65.1 160.4 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 SER A:687 A:687 14.0 0.122 -67.8 159.7 14.0 0.122 0.0 HOH
 9.520
 C
 O
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 SER A:687 A:687 11.0 0.096 -66.2 160.9 11.0 0.096 0.0 HOH
 9.266
 C
 O
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 SER A:687 A:687 13.0 0.113 -73.9 161.9 13.0 0.113 0.0 HOH
 9.653
 C
 O
SER C:687 C:687 7.0 0.061 -71.8 162.2 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 SER A:687 A:687 11.0 0.096 -74.1 161.5 11.0 0.096 0.0 HOH
 9.573
 C
 O
SER D:687 C:687 6.0 0.052 -71.5 162.1 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 SER A:687 A:687 13.0 0.113 -66.8 161.8 13.0 0.113 0.0 HOH
 9.327
 C
 O
SER D:687 C:687 4.0 0.035 -67.4 161.4 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 SER A:687 A:687 10.0 0.087 -73.3 162.3 10.0 0.087 0.0 HOH
 9.646
 C
 O
SER D:687 C:687 4.0 0.035 -73.7 161.3 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 SER A:687 A:687 9.0 0.078 -69.5 162.6 9.0 0.078 0.0 HOH
 9.506
 C
 O
SER D:687 C:687 3.0 0.026 -68.7 162.3 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 SER A:687 A:687 13.0 0.113 -74.2 161.4 13.0 0.113 0.0 HOH
 9.643
 C
 O
SER D:687 C:687 6.0 0.052 -72.1 162.2 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 SER A:687 A:687 12.0 0.104 -71.2 162.2 12.0 0.104 0.0 HOH
 9.647
 C
 O
SER D:687 C:687 4.0 0.035 -69.5 161.7 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 SER A:687 A:687 12.0 0.104 -73.7 162.6 12.0 0.104 0.0 HOH
 9.592
 C
 O
SER D:687 C:687 6.0 0.052 -72.0 162.4 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 SER A:669 A:687 12.0 0.104 -78.3 145.1 12.0 0.104 0.0 MF4
 8.373
 C
 F1
SER D:669 C:687 11.0 0.096 -79.6 145.6 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 SER A:669 A:687 9.0 0.078 -53.2 164.0 9.0 0.078 0.0 MF4
 7.633
 O
 F1
SER D:669 C:687 9.0 0.078 -52.5 165.7 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 SER A:663 A:687 21.0 0.183 -78.9 151.2 21.0 0.183 0.0
SER D:663 C:687 19.0 0.165 -79.4 150.8 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 SER A:699 A:694 12.0 0.104 -83.4 170.0 12.0 0.104 0.0 MF4
HOH
 7.562
3.720
 O
CA
 F1
O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 SER A:699 A:694 9.0 0.078 -81.2 171.1 9.0 0.078 0.0 MF4
HOH
 7.503
4.365
 O
N
 F1
O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.4 169.9 12.0 0.104 0.0 MF4
 7.563
 O
 F1
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.4 169.9 12.0 0.104 0.0 MF4
 7.562
 O
 F1
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.3 170.0 12.0 0.104 0.0 MF4
 7.562
 O
 F1
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.4 169.9 12.0 0.104 0.0 MF4
 7.562
 O
 F1
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.5 170.0 12.0 0.104 0.0 MF4
 7.563
 O
 F1
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.4 170.0 12.0 0.104 0.0 MF4
 7.563
 O
 F1
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.4 170.0 12.0 0.104 0.0 MF4
 7.563
 O
 F1
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.4 170.0 12.0 0.104 0.0 MF4
 7.561
 O
 F1
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.4 170.0 12.0 0.104 0.0 MF4
 7.562
 O
 F1
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.4 170.0 12.0 0.104 0.0 MF4
 7.563
 O
 F1
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.4 170.0 12.0 0.104 0.0 MF4
 7.562
 O
 F1
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.6 170.0 12.0 0.104 0.0 MF4
 7.563
 O
 F1
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.4 170.0 12.0 0.104 0.0 MF4
 7.562
 O
 F1
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.4 170.0 12.0 0.104 0.0 MF4
 7.562
 O
 F1
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.4 169.9 12.0 0.104 0.0 MF4
 7.562
 O
 F1
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.4 169.9 12.0 0.104 0.0 MF4
 7.563
 O
 F1
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.4 169.9 12.0 0.104 0.0 MF4
 7.562
 O
 F1
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.4 169.9 12.0 0.104 0.0 MF4
 7.562
 O
 F1
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 12.0 0.104 -83.4 170.0 12.0 0.104 0.0 MF4
 7.562
 O
 F1
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 SER A:699 A:694 9.0 0.078 -84.6 166.7 9.0 0.078 0.0 MF4
HOH
 7.563
3.501
 O
CB
 F1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 SER A:691 A:691 9.0 0.078 -82.0 159.7
af-p13637-f1 1 P13637 88.37 0.0 SER A:684 A:684 14.0 0.122 -81.6 159.5
af-p05023-f1 1 P05023 86.71 0.0 SER A:694 A:694 14.0 0.122 -78.5 159.9
af-q13733-f1 1 Q13733 80.48 0.0 SER A:700 A:700 14.0 0.122 -83.5 159.7