Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 160105251 | . | G | A | CCDS1196.1:NM_000702.3:c.2143Ggg>Agg_NP_000693.1:p.715G>R | Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4xe5 | 1 | Q08DA1 | 86.79 | 0.0 |
X-RAY |
2016-03-09 | GLY | A:716 | A:716 | 1.0 | 0.013 | S | -80.6 | -174.2 | 1.0 | 0.013 | 0.0 |
MG HOH |
4.280 4.022 |
N N |
MG O |
||
| 3wgu | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | GLY | A:711 | A:711 | 19.0 | 0.253 | S | -65.5 | 178.3 | 19.0 | 0.253 | 0.0 |
MG ALF MG ADP HOH |
5.380 5.221 3.517 6.931 4.589 |
CA CA N CA N |
MG F2 MG O1A O |
||
| GLY | D:711 | C:711 | 15.0 | 0.2 | S | -85.1 | 164.0 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | GLY | A:711 | A:711 | 20.0 | 0.267 | S | -60.1 | 174.3 | 20.0 | 0.267 | 0.0 |
MG ALF MG ADP HOH |
5.478 4.739 3.846 7.004 4.745 |
CA CA N CA N |
MG F2 MG O2A O |
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| GLY | D:711 | C:711 | 15.0 | 0.2 | S | -79.5 | 157.8 | NA | NA | NA | |||||||||||||
| 4hqj | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-10-02 | GLY | A:716 | A:711 | 11.0 | 0.147 | S | -77.1 | 165.3 | 11.0 | 0.147 | 0.0 |
ADP ALF MG |
7.195 5.718 4.150 |
CA N N |
O3A F3 MG |
||
| GLY | D:716 | C:711 | 12.0 | 0.16 | S | -77.4 | 165.4 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-06-26 | GLY | A:716 | A:711 | 1.0 | 0.013 | S | -104.2 | -167.6 | 1.0 | 0.013 | 0.0 |
MG |
5.103 |
N |
MG |
||
| GLY | D:716 | C:711 | 0.0 | 0.0 | S | -105.1 | -167.9 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | GLY | A:716 | A:711 | 1.0 | 0.013 | S | -92.5 | -174.7 | 1.0 | 0.013 | 0.0 |
MG |
4.632 |
N |
MG |
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| GLY | D:716 | C:711 | 1.0 | 0.013 | S | -92.8 | -173.7 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | GLY | A:716 | A:711 | 2.0 | 0.027 | S | -91.3 | -173.0 | 2.0 | 0.027 | 0.0 |
MG |
4.537 |
N |
MG |
||
| GLY | D:716 | C:711 | 1.0 | 0.013 | S | -91.0 | -173.1 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2021-07-07 | GLY | A:716 | A:711 | 0.0 | 0.0 | S | -73.8 | 175.2 | 0.0 | 0.0 | 0.0 |
MG HOH |
3.425 3.055 |
N N |
MG O |
||
| GLY | D:716 | C:711 | 0.0 | 0.0 | S | -73.6 | 175.5 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:711 | A:711 | 0.0 | 0.0 | S | -80.8 | 173.2 | 0.0 | 0.0 | 0.0 |
MG HOH |
3.694 2.990 |
N N |
MG O |
||
| 7d92 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:711 | A:711 | 1.0 | 0.013 | S | -81.7 | 174.0 | 1.0 | 0.013 | 0.0 |
MG HOH |
3.577 3.158 |
N N |
MG O |
||
| 7d93 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:711 | A:711 | 0.0 | 0.0 | S | -79.1 | 171.5 | 0.0 | 0.0 | 0.0 |
MG HOH |
3.600 2.959 |
N N |
MG O |
||
| GLY | C:711 | C:711 | 0.0 | 0.0 | S | -79.3 | 170.4 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:711 | A:711 | 0.0 | 0.0 | S | -79.6 | 171.5 | 0.0 | 0.0 | 0.0 |
MG HOH |
3.578 2.958 |
N N |
MG O |
||
| GLY | D:711 | C:711 | 1.0 | 0.013 | S | -80.2 | 170.3 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:711 | A:711 | 0.0 | 0.0 | S | -81.0 | 174.4 | 0.0 | 0.0 | 0.0 |
MG HOH |
3.738 3.385 |
N N |
MG O |
||
| GLY | D:711 | C:711 | 0.0 | 0.0 | S | -81.1 | 173.3 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:711 | A:711 | 0.0 | 0.0 | S | -75.9 | 178.9 | 0.0 | 0.0 | 0.0 |
MG HOH |
3.546 3.083 |
N N |
MG O |
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| GLY | D:711 | C:711 | 0.0 | 0.0 | S | -76.0 | 178.4 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:711 | A:711 | 0.0 | 0.0 | S | -71.9 | 177.4 | 0.0 | 0.0 | 0.0 |
MG HOH |
3.485 2.908 |
N N |
MG O |
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| GLY | D:711 | C:711 | 0.0 | 0.0 | S | -71.4 | 176.6 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:711 | A:711 | 0.0 | 0.0 | S | -79.1 | 171.0 | 0.0 | 0.0 | 0.0 |
MG HOH |
3.575 2.995 |
N N |
MG O |
||
| GLY | D:711 | C:711 | 1.0 | 0.013 | S | -80.0 | 169.8 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:711 | A:711 | 0.0 | 0.0 | S | -74.1 | 173.0 | 0.0 | 0.0 | 0.0 |
MG HOH |
3.489 3.139 |
N N |
MG O |
||
| GLY | D:711 | C:711 | 1.0 | 0.013 | S | -74.1 | 171.9 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | GLY | A:711 | A:711 | 0.0 | 0.0 | S | -78.9 | 172.8 | 0.0 | 0.0 | 0.0 |
MG HOH |
3.510 2.928 |
N N |
MG O |
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| GLY | D:711 | C:711 | 0.0 | 0.0 | S | -80.9 | 172.4 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2007-12-18 | GLY | A:693 | A:711 | 19.0 | 0.253 | S | -79.1 | 167.6 | 19.0 | 0.253 | 0.0 |
MG MF4 |
3.984 5.736 |
N N |
MG F2 |
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| GLY | D:693 | C:711 | 18.0 | 0.24 | S | -80.1 | 168.2 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2010-02-16 | GLY | A:693 | A:711 | 13.0 | 0.173 | S | -111.5 | 142.6 | 13.0 | 0.173 | 0.0 |
MF4 MG |
5.764 4.207 |
CA N |
F2 MG |
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| GLY | D:693 | C:711 | 13.0 | 0.173 | S | -113.7 | 144.7 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | GLY | A:687 | A:711 | 2.0 | 0.027 | S | -70.7 | 146.4 | 2.0 | 0.027 | 0.0 |
MG |
3.610 |
N |
MG |
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| GLY | D:687 | C:711 | 2.0 | 0.027 | S | -69.6 | 146.7 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-05-19 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.3 | 168.7 | 10.0 | 0.133 | 0.0 |
MF4 MG HOH |
5.609 4.245 3.082 |
N N N |
F2 MG O |
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| 3a3y | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-09-08 | GLY | A:723 | A:718 | 9.0 | 0.12 | S | -127.0 | 170.3 | 9.0 | 0.12 | 0.0 |
MF4 MG HOH |
5.766 4.408 3.088 |
N N N |
F2 MG O |
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| 5avq | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.3 | 168.7 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.609 4.245 |
N N |
F2 MG |
||
| 5avr | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.4 | 168.7 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.610 4.246 |
N N |
F2 MG |
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| 5avs | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.4 | 168.7 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.610 4.246 |
N N |
F2 MG |
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| 5avt | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.3 | 168.7 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.608 4.245 |
N N |
F2 MG |
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| 5avu | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.3 | 168.7 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.609 4.245 |
N N |
F2 MG |
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| 5avv | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.3 | 168.7 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.609 4.245 |
N N |
F2 MG |
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| 5avw | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.4 | 168.7 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.610 4.246 |
N N |
F2 MG |
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| 5avx | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.4 | 168.7 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.609 4.244 |
N N |
F2 MG |
||
| 5avy | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.4 | 168.7 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.610 4.246 |
N N |
F2 MG |
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| 5avz | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.2 | 168.7 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.609 4.245 |
N N |
F2 MG |
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| 5aw0 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.3 | 168.8 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.608 4.245 |
N N |
F2 MG |
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| 5aw1 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.4 | 168.8 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.608 4.244 |
N N |
F2 MG |
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| 5aw2 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.3 | 168.7 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.609 4.245 |
N N |
F2 MG |
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| 5aw3 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.3 | 168.7 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.610 4.246 |
N N |
F2 MG |
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| 5aw4 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.3 | 168.7 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.609 4.245 |
N N |
F2 MG |
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| 5aw5 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.4 | 168.7 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.609 4.246 |
N N |
F2 MG |
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| 5aw6 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.3 | 168.7 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.609 4.245 |
N N |
F2 MG |
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| 5aw7 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.4 | 168.7 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.609 4.246 |
N N |
F2 MG |
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| 5aw8 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 10.0 | 0.133 | S | -107.4 | 168.7 | 10.0 | 0.133 | 0.0 |
MF4 MG |
5.610 4.246 |
N N |
F2 MG |
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| 5aw9 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | GLY | A:723 | A:718 | 9.0 | 0.12 | S | -104.3 | 170.4 | 9.0 | 0.12 | 0.0 |
MF4 MG HOH |
5.633 4.116 3.110 |
N N N |
F2 MG O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p50993-f1 | 1 | P50993 | 100.0 | 0.0 | GLY | A:715 | A:715 | 10.0 | 0.133 | S | -81.2 | 169.7 | |
| af-p13637-f1 | 1 | P13637 | 88.37 | 0.0 | GLY | A:708 | A:708 | 8.0 | 0.107 | S | -79.5 | 168.7 | |
| af-p05023-f1 | 1 | P05023 | 86.71 | 0.0 | GLY | A:718 | A:718 | 9.0 | 0.12 | S | -78.1 | 168.5 | |
| af-q13733-f1 | 1 | Q13733 | 80.48 | 0.0 | GLY | A:724 | A:724 | 9.0 | 0.12 | S | -82.2 | 170.1 | |