Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 160105259 | . | C | A | CCDS1196.1:NM_000702.3:c.2151aaC>aaA_NP_000693.1:p.717N>K | Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4xe5 | 1 | Q08DA1 | 86.79 | 0.0 |
X-RAY |
2016-03-09 | ASN | A:718 | A:718 | 0.0 | 0.0 | G | -67.2 | -15.6 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.526 2.596 |
ND2 ND2 |
MG O |
||
| 3wgu | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | ASN | A:713 | A:713 | 23.0 | 0.144 | T | -79.1 | -14.6 | 23.0 | 0.144 | 0.0 |
MG ALF MG ADP HOH |
4.813 2.825 3.859 3.490 5.529 |
OD1 ND2 OD1 ND2 OD1 |
MG F2 MG O1A O |
||
| ASN | D:713 | C:713 | 22.0 | 0.138 | G | -79.3 | -1.6 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | ASN | A:713 | A:713 | 21.0 | 0.131 | T | -71.4 | -15.0 | 21.0 | 0.131 | 0.0 |
MG ALF MG ADP HOH |
5.226 3.092 4.582 3.241 6.509 |
ND2 OD1 OD1 ND2 OD1 |
MG F2 MG O2A O |
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| ASN | D:713 | C:713 | 20.0 | 0.125 | G | -78.9 | -0.0 | NA | NA | NA | |||||||||||||
| 4hqj | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-10-02 | ASN | A:718 | A:713 | 47.0 | 0.294 | G | -66.0 | -8.2 | 47.0 | 0.294 | 0.0 |
ADP ALF MG |
2.808 3.768 4.926 |
ND2 OD1 OD1 |
O1A F1 MG |
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| ASN | D:718 | C:713 | 48.0 | 0.3 | G | -66.7 | -6.8 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-06-26 | ASN | A:718 | A:713 | 1.0 | 0.006 | G | -69.1 | -18.8 | 1.0 | 0.006 | 0.0 |
MG |
4.983 |
ND2 |
MG |
||
| ASN | D:718 | C:713 | 1.0 | 0.006 | G | -69.0 | -18.6 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | ASN | A:718 | A:713 | 2.0 | 0.013 | G | -64.5 | -18.9 | 2.0 | 0.013 | 0.0 |
MG |
4.556 |
ND2 |
MG |
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| ASN | D:718 | C:713 | 3.0 | 0.019 | G | -64.2 | -18.8 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | ASN | A:718 | A:713 | 1.0 | 0.006 | G | -64.1 | -17.6 | 1.0 | 0.006 | 0.0 |
MG |
4.950 |
OD1 |
MG |
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| ASN | D:718 | C:713 | 1.0 | 0.006 | G | -63.8 | -17.7 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2021-07-07 | ASN | A:718 | A:713 | 0.0 | 0.0 | G | -68.0 | -20.3 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.781 2.420 |
OD1 OD1 |
MG O |
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| ASN | D:718 | C:713 | 0.0 | 0.0 | G | -69.1 | -21.9 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASN | A:713 | A:713 | 0.0 | 0.0 | G | -74.9 | -13.6 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.358 2.537 |
OD1 OD1 |
MG O |
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| 7d92 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASN | A:713 | A:713 | 0.0 | 0.0 | G | -74.2 | -14.4 | 0.0 | 0.0 | 0.0 |
MG HOH |
4.371 2.403 |
OD1 OD1 |
MG O |
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| 7d93 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASN | A:713 | A:713 | 3.0 | 0.019 | G | -67.4 | -16.4 | 3.0 | 0.019 | 0.0 |
MG HOH |
4.570 2.506 |
OD1 OD1 |
MG O |
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| ASN | C:713 | C:713 | 2.0 | 0.013 | G | -66.7 | -15.4 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASN | A:713 | A:713 | 2.0 | 0.013 | G | -66.9 | -16.5 | 2.0 | 0.013 | 0.0 |
MG HOH |
4.350 2.461 |
OD1 OD1 |
MG O |
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| ASN | D:713 | C:713 | 1.0 | 0.006 | G | -66.4 | -15.2 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASN | A:713 | A:713 | 1.0 | 0.006 | G | -68.3 | -20.9 | 1.0 | 0.006 | 0.0 |
MG HOH |
4.537 2.617 |
OD1 OD1 |
MG O |
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| ASN | D:713 | C:713 | 0.0 | 0.0 | G | -69.0 | -20.6 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASN | A:713 | A:713 | 1.0 | 0.006 | G | -67.7 | -21.0 | 1.0 | 0.006 | 0.0 |
MG HOH |
4.640 2.490 |
OD1 OD1 |
MG O |
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| ASN | D:713 | C:713 | 0.0 | 0.0 | G | -67.7 | -22.2 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASN | A:713 | A:713 | 1.0 | 0.006 | T | -65.0 | -26.4 | 1.0 | 0.006 | 0.0 |
MG HOH |
4.773 2.571 |
OD1 OD1 |
MG O |
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| ASN | D:713 | C:713 | 0.0 | 0.0 | T | -64.9 | -26.5 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASN | A:713 | A:713 | 3.0 | 0.019 | G | -67.4 | -15.6 | 3.0 | 0.019 | 0.0 |
MG HOH |
4.507 2.527 |
OD1 OD1 |
MG O |
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| ASN | D:713 | C:713 | 1.0 | 0.006 | G | -66.9 | -14.5 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASN | A:713 | A:713 | 1.0 | 0.006 | G | -67.4 | -22.7 | 1.0 | 0.006 | 0.0 |
MG HOH |
4.734 2.846 |
OD1 OD1 |
MG O |
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| ASN | D:713 | C:713 | 0.0 | 0.0 | G | -66.6 | -22.6 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASN | A:713 | A:713 | 2.0 | 0.013 | G | -67.5 | -16.2 | 2.0 | 0.013 | 0.0 |
MG HOH |
4.475 2.570 |
OD1 OD1 |
MG O |
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| ASN | D:713 | C:713 | 1.0 | 0.006 | G | -67.2 | -16.6 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2007-12-18 | ASN | A:695 | A:713 | 2.0 | 0.013 | T | -60.7 | -15.2 | 2.0 | 0.013 | 0.0 |
MG MF4 |
4.515 3.363 |
OD1 ND2 |
MG F1 |
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| ASN | D:695 | C:713 | 1.0 | 0.006 | G | -59.7 | -16.0 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2010-02-16 | ASN | A:695 | A:713 | 1.0 | 0.006 | T | -68.0 | -9.1 | 1.0 | 0.006 | 0.0 |
MF4 MG |
3.617 4.273 |
ND2 OD1 |
F1 MG |
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| ASN | D:695 | C:713 | 2.0 | 0.013 | T | -70.6 | -8.5 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | ASN | A:689 | A:713 | 0.0 | 0.0 | G | -74.4 | 16.3 | 0.0 | 0.0 | 0.0 |
MG |
4.238 |
OD1 |
MG |
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| ASN | D:689 | C:713 | 0.0 | 0.0 | G | -73.0 | 16.0 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-05-19 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.5 | -1.3 | 0.0 | 0.0 | 0.0 |
MF4 MG HOH |
2.917 5.069 2.753 |
ND2 OD1 O |
F1 MG O |
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| 3a3y | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-09-08 | ASN | A:725 | A:720 | 0.0 | 0.0 | T | -83.8 | -9.2 | 0.0 | 0.0 | 0.0 |
MF4 MG HOH |
2.943 4.966 2.922 |
ND2 OD1 OD1 |
F1 MG O |
||
| 5avq | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.4 | -1.3 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.918 5.069 |
ND2 OD1 |
F1 MG |
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| 5avr | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.4 | -1.3 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.917 5.069 |
ND2 OD1 |
F1 MG |
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| 5avs | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.5 | -1.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.917 5.070 |
ND2 OD1 |
F1 MG |
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| 5avt | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.5 | -1.3 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.917 5.069 |
ND2 OD1 |
F1 MG |
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| 5avu | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.6 | -1.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.918 5.069 |
ND2 OD1 |
F1 MG |
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| 5avv | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.4 | -1.4 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.917 5.070 |
ND2 OD1 |
F1 MG |
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| 5avw | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.5 | -1.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.918 5.069 |
ND2 OD1 |
F1 MG |
||
| 5avx | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.5 | -1.3 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.918 5.069 |
ND2 OD1 |
F1 MG |
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| 5avy | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.5 | -1.1 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.917 5.070 |
ND2 OD1 |
F1 MG |
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| 5avz | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.5 | -1.3 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.918 5.070 |
ND2 OD1 |
F1 MG |
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| 5aw0 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.5 | -1.3 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.917 5.069 |
ND2 OD1 |
F1 MG |
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| 5aw1 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.5 | -1.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.917 5.069 |
ND2 OD1 |
F1 MG |
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| 5aw2 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.5 | -1.3 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.917 5.070 |
ND2 OD1 |
F1 MG |
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| 5aw3 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.5 | -1.3 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.916 5.069 |
ND2 OD1 |
F1 MG |
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| 5aw4 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.5 | -1.3 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.917 5.070 |
ND2 OD1 |
F1 MG |
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| 5aw5 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.5 | -1.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.917 5.070 |
ND2 OD1 |
F1 MG |
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| 5aw6 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.4 | -1.3 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.918 5.069 |
ND2 OD1 |
F1 MG |
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| 5aw7 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.6 | -1.2 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.917 5.070 |
ND2 OD1 |
F1 MG |
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| 5aw8 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -75.3 | -1.4 | 0.0 | 0.0 | 0.0 |
MF4 MG |
2.917 5.070 |
ND2 OD1 |
F1 MG |
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| 5aw9 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASN | A:725 | A:720 | 0.0 | 0.0 | G | -67.9 | -3.3 | 0.0 | 0.0 | 0.0 |
MF4 MG HOH |
2.833 4.844 2.935 |
ND2 OD1 O |
F1 MG O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p50993-f1 | 1 | P50993 | 100.0 | 0.0 | ASN | A:717 | A:717 | 2.0 | 0.013 | G | -57.6 | -25.7 | |
| af-p13637-f1 | 1 | P13637 | 88.37 | 0.0 | ASN | A:710 | A:710 | 2.0 | 0.013 | G | -55.9 | -26.0 | |
| af-p05023-f1 | 1 | P05023 | 86.71 | 0.0 | ASN | A:720 | A:720 | 1.0 | 0.006 | G | -56.0 | -25.7 | |
| af-q13733-f1 | 1 | Q13733 | 80.48 | 0.0 | ASN | A:726 | A:726 | 3.0 | 0.019 | G | -56.9 | -28.1 | |