Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 160105260 | . | G | A | CCDS1196.1:NM_000702.3:c.2152Gac>Aac_NP_000693.1:p.718D>N | Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4xe5 | 1 | Q08DA1 | 86.79 | 0.0 |
X-RAY |
2016-03-09 | ASP | A:719 | A:719 | 3.0 | 0.02 | G | -95.1 | -4.6 | 3.0 | 0.02 | 0.0 |
MG HOH |
3.956 3.032 |
OD2 OD2 |
MG O |
||
| 3wgu | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | ASP | A:714 | A:714 | 2.0 | 0.013 | T | -79.4 | -16.7 | 2.0 | 0.013 | 0.0 |
MG ALF MG ADP HOH |
7.360 4.087 3.822 7.073 6.274 |
OD1 OD1 OD2 OD1 OD2 |
MG F2 MG O1A O |
||
| ASP | D:714 | C:714 | 1.0 | 0.007 | G | -92.2 | -16.7 | NA | NA | NA | |||||||||||||
| 3wgv | 1 | I7HD36 | 87.32 | 0.0 |
X-RAY |
2013-10-09 | ASP | A:714 | A:714 | 2.0 | 0.013 | T | -87.0 | 0.6 | 2.0 | 0.013 | 0.0 |
MG ALF MG ADP HOH |
7.464 4.180 3.921 6.803 6.572 |
OD2 OD2 OD2 OD1 OD2 |
MG F2 MG O3A O |
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| ASP | D:714 | C:714 | 3.0 | 0.02 | G | -97.4 | -16.6 | NA | NA | NA | |||||||||||||
| 4hqj | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-10-02 | ASP | A:719 | A:714 | 3.0 | 0.02 | G | -78.4 | -30.1 | 3.0 | 0.02 | 0.0 |
ADP ALF MG |
6.333 3.977 4.230 |
OD1 OD1 OD2 |
O3B F1 MG |
||
| ASP | D:719 | C:714 | 2.0 | 0.013 | G | -80.6 | -29.3 | NA | NA | NA | |||||||||||||
| 4hyt | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2013-06-26 | ASP | A:719 | A:714 | 2.0 | 0.013 | G | -92.3 | 4.9 | 2.0 | 0.013 | 0.0 |
MG MG |
4.869 9.700 |
OD2 O |
MG MG |
||
| ASP | D:719 | C:714 | 2.0 | 0.013 | G | -92.5 | 4.1 | NA | NA | NA | |||||||||||||
| 4res | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | ASP | A:719 | A:714 | 4.0 | 0.027 | G | -95.8 | 5.6 | 4.0 | 0.027 | 0.0 |
K MG |
9.019 4.801 |
O OD2 |
K MG |
||
| ASP | D:719 | C:714 | 3.0 | 0.02 | G | -95.5 | 5.4 | NA | NA | NA | |||||||||||||
| 4ret | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2015-01-28 | ASP | A:719 | A:714 | 2.0 | 0.013 | G | -96.2 | 3.2 | 2.0 | 0.013 | 0.0 |
MG MG |
4.707 9.919 |
OD2 O |
MG MG |
||
| ASP | D:719 | C:714 | 2.0 | 0.013 | G | -96.3 | 3.0 | NA | NA | NA | |||||||||||||
| 7evx | 1 | P05024 | 86.69 | 0.0 |
X-RAY |
2021-07-07 | ASP | A:719 | A:714 | 3.0 | 0.02 | G | -85.7 | -6.6 | 3.0 | 0.02 | 0.0 |
MG NA HOH |
3.839 9.875 2.783 |
OD2 O OD2 |
MG NA O |
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| ASP | D:719 | C:714 | 2.0 | 0.013 | G | -85.2 | -4.8 | NA | NA | NA | |||||||||||||
| 7d91 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:714 | A:714 | 3.0 | 0.02 | G | -98.5 | 1.1 | 3.0 | 0.02 | 0.0 |
MG MG HOH |
3.701 9.436 2.463 |
OD2 O OD2 |
MG MG O |
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| 7d92 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:714 | A:714 | 3.0 | 0.02 | G | -100.4 | 1.0 | 3.0 | 0.02 | 0.0 |
MG MG HOH |
3.706 9.371 2.559 |
OD2 O OD2 |
MG MG O |
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| 7d93 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:714 | A:714 | 3.0 | 0.02 | G | -91.3 | -1.9 | 3.0 | 0.02 | 0.0 |
MG NA HOH |
4.051 9.814 2.587 |
OD2 O OD2 |
MG NA O |
||
| ASP | C:714 | C:714 | 3.0 | 0.02 | G | -90.9 | -1.7 | NA | NA | NA | |||||||||||||
| 7d94 | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:714 | A:714 | 3.0 | 0.02 | G | -91.1 | -1.8 | 3.0 | 0.02 | 0.0 |
MG NA HOH |
3.821 9.740 2.429 |
OD2 O OD2 |
MG NA O |
||
| ASP | D:714 | C:714 | 3.0 | 0.02 | G | -90.9 | -2.5 | NA | NA | NA | |||||||||||||
| 7ddf | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:714 | A:714 | 3.0 | 0.02 | G | -91.1 | 3.5 | 3.0 | 0.02 | 0.0 |
MG HOH |
3.798 2.532 |
OD2 OD2 |
MG O |
||
| ASP | D:714 | C:714 | 3.0 | 0.02 | G | -90.4 | 5.8 | NA | NA | NA | |||||||||||||
| 7ddh | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:714 | A:714 | 2.0 | 0.013 | G | -90.4 | 2.3 | 2.0 | 0.013 | 0.0 |
MG HOH |
3.916 2.878 |
OD2 OD2 |
MG O |
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| ASP | D:714 | C:714 | 2.0 | 0.013 | G | -88.3 | 3.6 | NA | NA | NA | |||||||||||||
| 7ddi | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:714 | A:714 | 3.0 | 0.02 | H | -83.5 | 3.3 | 3.0 | 0.02 | 0.0 |
MG HOH |
3.969 2.612 |
OD2 OD2 |
MG O |
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| ASP | D:714 | C:714 | 3.0 | 0.02 | H | -82.2 | 3.0 | NA | NA | NA | |||||||||||||
| 7ddj | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:714 | A:714 | 2.0 | 0.013 | G | -91.2 | -2.0 | 2.0 | 0.013 | 0.0 |
MG HOH |
3.983 2.742 |
OD2 OD2 |
MG O |
||
| ASP | D:714 | C:714 | 3.0 | 0.02 | G | -91.9 | -2.0 | NA | NA | NA | |||||||||||||
| 7ddk | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:714 | A:714 | 3.0 | 0.02 | G | -86.6 | 0.5 | 3.0 | 0.02 | 0.0 |
MG NA HOH |
3.743 9.915 2.814 |
OD2 O OD2 |
MG NA O |
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| ASP | D:714 | C:714 | 2.0 | 0.013 | G | -85.0 | 0.0 | NA | NA | NA | |||||||||||||
| 7ddl | 1 | P05024 | 86.82 | 0.0 |
X-RAY |
2021-01-27 | ASP | A:714 | A:714 | 3.0 | 0.02 | G | -90.5 | -0.3 | 3.0 | 0.02 | 0.0 |
MG NA HOH |
3.961 9.922 2.367 |
OD2 O OD2 |
MG NA O |
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| ASP | D:714 | C:714 | 3.0 | 0.02 | G | -90.1 | 0.3 | NA | NA | NA | |||||||||||||
| 3b8e | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2007-12-18 | ASP | A:696 | A:714 | 1.0 | 0.007 | T | -83.4 | -38.6 | 1.0 | 0.007 | 0.0 |
MG MF4 |
4.795 4.353 |
OD2 OD1 |
MG F1 |
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| ASP | D:696 | C:714 | 0.0 | 0.0 | G | -83.2 | -38.7 | NA | NA | NA | |||||||||||||
| 3kdp | 1 | P05024 | 87.56 | 0.0 |
X-RAY |
2010-02-16 | ASP | A:696 | A:714 | 3.0 | 0.02 | T | -98.1 | -31.9 | 3.0 | 0.02 | 0.0 |
MF4 MG |
4.571 4.420 |
OD1 OD2 |
F1 MG |
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| ASP | D:696 | C:714 | 4.0 | 0.027 | T | -99.0 | -33.9 | NA | NA | NA | |||||||||||||
| 3n23 | 1 | P05024 | 87.8 | 0.0 |
X-RAY |
2011-01-19 | ASP | A:690 | A:714 | 1.0 | 0.007 | G | -117.4 | -22.4 | 1.0 | 0.007 | 0.0 |
MG |
3.732 |
OD2 |
MG |
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| ASP | D:690 | C:714 | 1.0 | 0.007 | G | -118.1 | -22.7 | NA | NA | NA | |||||||||||||
| 2zxe | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-05-19 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.7 | -7.3 | 2.0 | 0.013 | 0.0 |
MF4 MG K HOH |
4.255 4.194 8.866 2.722 |
OD1 OD2 O OD2 |
F1 MG K O |
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| 3a3y | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2009-09-08 | ASP | A:726 | A:721 | 1.0 | 0.007 | S | -92.1 | -8.3 | 1.0 | 0.007 | 0.0 |
MF4 MG K HOH |
3.872 4.188 9.599 2.549 |
OD1 OD2 O OD2 |
F1 MG K O |
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| 5avq | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.7 | -7.3 | 2.0 | 0.013 | 0.0 |
MF4 MG K TL |
4.255 4.195 8.865 8.865 |
OD1 OD2 O O |
F1 MG K TL |
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| 5avr | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.7 | -7.3 | 2.0 | 0.013 | 0.0 |
MF4 MG K TL |
4.255 4.194 8.865 8.865 |
OD1 OD2 O O |
F1 MG K TL |
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| 5avs | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.7 | -7.2 | 2.0 | 0.013 | 0.0 |
MF4 MG K TL |
4.255 4.195 8.867 8.867 |
OD1 OD2 O O |
F1 MG K TL |
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| 5avt | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.7 | -7.3 | 2.0 | 0.013 | 0.0 |
MF4 MG K TL |
4.255 4.194 8.866 8.866 |
OD1 OD2 O O |
F1 MG K TL |
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| 5avu | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.7 | -7.3 | 2.0 | 0.013 | 0.0 |
MF4 MG K TL |
4.254 4.194 8.866 8.866 |
OD1 OD2 O O |
F1 MG K TL |
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| 5avv | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.7 | -7.3 | 2.0 | 0.013 | 0.0 |
MF4 MG K TL |
4.256 4.195 8.866 8.866 |
OD1 OD2 O O |
F1 MG K TL |
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| 5avw | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.7 | -7.3 | 2.0 | 0.013 | 0.0 |
MF4 MG K TL |
4.256 4.195 8.866 8.866 |
OD1 OD2 O O |
F1 MG K TL |
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| 5avx | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.6 | -7.4 | 2.0 | 0.013 | 0.0 |
MF4 MG K TL |
4.255 4.194 8.866 8.866 |
OD1 OD2 O O |
F1 MG K TL |
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| 5avy | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.8 | -7.3 | 2.0 | 0.013 | 0.0 |
MF4 MG K TL |
4.254 4.195 8.865 8.865 |
OD1 OD2 O O |
F1 MG K TL |
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| 5avz | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.7 | -7.3 | 2.0 | 0.013 | 0.0 |
MF4 MG K TL |
4.255 4.194 8.866 8.866 |
OD1 OD2 O O |
F1 MG K TL |
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| 5aw0 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.7 | -7.2 | 2.0 | 0.013 | 0.0 |
MF4 MG K TL |
4.256 4.194 8.865 8.865 |
OD1 OD2 O O |
F1 MG K TL |
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| 5aw1 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.7 | -7.4 | 2.0 | 0.013 | 0.0 |
MF4 MG K TL |
4.255 4.194 8.867 8.867 |
OD1 OD2 O O |
F1 MG K TL |
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| 5aw2 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.7 | -7.3 | 2.0 | 0.013 | 0.0 |
MF4 MG K TL |
4.254 4.195 8.866 8.866 |
OD1 OD2 O O |
F1 MG K TL |
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| 5aw3 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.7 | -7.3 | 2.0 | 0.013 | 0.0 |
MF4 MG K TL |
4.253 4.195 8.866 8.866 |
OD1 OD2 O O |
F1 MG K TL |
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| 5aw4 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.8 | -7.3 | 2.0 | 0.013 | 0.0 |
MF4 MG K RB |
4.255 4.195 8.866 8.866 |
OD1 OD2 O O |
F1 MG K RB |
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| 5aw5 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.8 | -7.3 | 2.0 | 0.013 | 0.0 |
MF4 MG K RB |
4.255 4.196 8.866 8.866 |
OD1 OD2 O O |
F1 MG K RB |
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| 5aw6 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.8 | -7.2 | 2.0 | 0.013 | 0.0 |
MF4 MG K RB |
4.254 4.195 8.864 8.864 |
OD1 OD2 O O |
F1 MG K RB |
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| 5aw7 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.8 | -7.2 | 2.0 | 0.013 | 0.0 |
MF4 MG K RB |
4.254 4.195 8.865 8.865 |
OD1 OD2 O O |
F1 MG K RB |
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| 5aw8 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -100.7 | -7.3 | 2.0 | 0.013 | 0.0 |
MF4 MG RB |
4.255 4.196 8.866 |
OD1 OD2 O |
F1 MG RB |
||
| 5aw9 | 1 | Q4H132 | 84.65 | 0.0 |
X-RAY |
2015-09-02 | ASP | A:726 | A:721 | 2.0 | 0.013 | G | -101.2 | -4.3 | 2.0 | 0.013 | 0.0 |
MF4 MG K HOH |
4.336 4.200 8.821 2.705 |
OD1 OD2 O OD2 |
F1 MG K O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p50993-f1 | 1 | P50993 | 100.0 | 0.0 | ASP | A:718 | A:718 | 2.0 | 0.013 | G | -82.9 | -14.5 | |
| af-p13637-f1 | 1 | P13637 | 88.37 | 0.0 | ASP | A:711 | A:711 | 3.0 | 0.02 | G | -84.0 | -15.6 | |
| af-p05023-f1 | 1 | P05023 | 86.71 | 0.0 | ASP | A:721 | A:721 | 2.0 | 0.013 | G | -83.3 | -16.1 | |
| af-q13733-f1 | 1 | Q13733 | 80.48 | 0.0 | ASP | A:727 | A:727 | 3.0 | 0.02 | G | -82.6 | -15.7 | |